Dr. Awomolo studies various aspects of maternal health and blood-related conditions. Her research includes examining cortisol levels in pregnant women to understand stress effects, especially among Black women and single mothers. She also investigates how bedsharing among breastfeeding mothers influences the duration of breastfeeding, revealing that bedsharing can lead to longer breastfeeding periods and better health for children. Furthermore, Dr. Awomolo evaluates risk assessment tools for preventing blood clots in pregnant women, aiming to enhance patient safety and care during hospitalization.
Key findings
Cortisol levels in hair increased during pregnancy, peaked in the third trimester, and decreased postpartum, with Black women and single mothers having notably higher levels during the postpartum period.
68% of surveyed breastfeeding physicians shared beds with their babies, leading to an average breastfeeding duration of 18 months, compared to 14 months for those who did not.
Using the RCOG guidelines effectively identified 20% of pregnant women at risk of blood clots antepartum and 53% postpartum, compared to only 12% and 24% with ACOG guidelines.
A case study highlighted a rare rectal laceration occurring during childbirth without anal sphincter injury, emphasizing the importance of recognizing this condition.
A 50% reduction in megakaryocyte migration was observed when dynamins were blocked, crucial for understanding blood clotting mechanisms.
Frequently asked questions
Does Dr. Awomolo study pregnancy-related health issues?
Yes, she focuses on maternal health, including stress during pregnancy and risks related to blood clots.
What impact does Dr. Awomolo's research have on breastfeeding?
Her findings show that bedsharing among breastfeeding mothers can lead to longer breastfeeding duration, which positively affects child health.
How does Dr. Awomolo's work help patients?
Her research helps identify at-risk pregnant women for conditions like blood clots, ensuring they receive appropriate preventive care.
What is the significance of Dr. Awomolo's work on blood platelets?
Her research investigates how specific proteins affect platelet production, which is essential for patients requiring blood clotting support.
What types of injuries related to childbirth does Dr. Awomolo study?
She studies rare childbirth injuries, such as rectal lacerations occurring without anal sphincter injuries, to improve treatment approaches.
Publications in plain English
Bedsharing among breastfeeding physicians: Results of a nationwide survey.
2024
PloS one
Louis-Jacques AF, Bartick M, Awomolo A, Zhang J, Feldman-Winter L +4 more
Plain English This study looked at whether doctors who breastfeed share their beds with their babies and how this affects breastfeeding duration. Among the 546 physicians surveyed, 68% reported that they shared beds with their babies, and those who did breastfed for an average of 18 months, compared to 14 months for non-bedsharers. This finding is important because longer breastfeeding can lead to better health outcomes for children, and it highlights a gap in communication between parents and healthcare providers about safe bedsharing practices.
Who this helps: This helps parents and healthcare providers.
Trends in hair cortisol from preconception to the postpartum period.
2024
Psychoneuroendocrinology
Louis-Jacques AF, Villarreal XP, Campos A, Urmi S, Dutra SVO +4 more
Plain English This study looked at cortisol levels in hair to understand stress in women before and after childbirth. Researchers found that cortisol levels increased during pregnancy, peaked in the third trimester, and then decreased after birth. Notably, Black women and single mothers showed higher cortisol levels during the postpartum period, which may contribute to understanding racial disparities in maternal health.
Who this helps: This information helps healthcare providers and researchers work towards better support and care for mothers, especially those in high-stress situations.
A comparison of pregnancy-specific risk scoring systems for venous thromboembolic pharmacoprophylaxis in hospitalized maternity patients.
2022
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Gomez D, Orfanelli T, Awomolo A, Doulaveris G, Rosen T +1 more
Plain English This study looked at two different scoring systems to identify pregnant women who might need medication to prevent dangerous blood clots during and after hospital stays. Researchers found that using the Royal College of Obstetricians & Gynecologists (RCOG) guidelines identified more at-risk women—20% for antepartum (before birth) and 53% for postpartum (after birth)—compared to the American College of Obstetricians and Gynecologists (ACOG) guidelines, which identified only 12% and 24%, respectively. This is important because using the ACOG guidelines at a slightly higher threshold could have potentially prevented all cases of blood clots related to hospitalization without causing too much bleeding.
Who this helps: This helps pregnant patients by identifying those at risk for blood clots, ensuring they receive necessary preventive care.
Obstetric rectal laceration in the absence of an anal sphincter injury.
2021
BMJ case reports
Awomolo A, Hardman D, Louis-Jacques A
Plain English This study looked at a rare type of injury that can occur during childbirth, called a rectal laceration, which happens without damage to the anal sphincter muscle. The research focused on a 30-year-old woman who, after a challenging labor complicated by high blood pressure, delivered a healthy baby but had a problem where stool was found in her vagina. The medical team successfully repaired the injury and she recovered well, highlighting the importance of recognizing and treating this unusual condition.
Who this helps: This helps doctors by improving their understanding of rare childbirth injuries and informing their treatment approaches.
Trends in invasive prenatal diagnostic testing at a single institution.
2018
Prenatal diagnosis
Awomolo A, Palomares K, Garcia GH, Rosen T, Duzyj C +1 more
Plain English This study looked at trends in invasive prenatal testing, which are medical procedures used to diagnose potential genetic issues in unborn babies, between 2006 and 2015. Researchers found that the number of amniocentesis tests has steadily decreased, while the number of chorionic villus sampling (CVS) tests has increased and is now similar in frequency; importantly, the rate of abnormal results from these tests rose from 11.4% to 27%. These changes matter because they reflect how testing practices have shifted over time and indicate that fewer women are tested solely due to advanced maternal age.
Who this helps: This information benefits patients and their doctors by providing insights into evolving prenatal testing practices.
Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity.
2018
Blood advances
Suraneni PK, Corey SJ, Hession MJ, Ishaq R, Awomolo A +8 more
Plain English Researchers studied how certain proteins called dynamins affect the movement of megakaryocytes, which are cells that produce blood platelets. They found that blocking the action of dynamins reduced the cells' ability to migrate, as seen by a 50% drop in their directional movement in experiments. This is important because understanding how megakaryocytes move can help improve platelet production, which is vital for blood clotting and healing.
Who this helps: This helps patients who need improved platelet production, such as those undergoing chemotherapy or with blood disorders.
Functionality of the three-site ferroxidase center of Escherichia coli bacterial ferritin (EcFtnA).
2014
Biochemistry
Bou-Abdallah F, Yang H, Awomolo A, Cooper B, Woodhall MR +2 more
Plain English This study focused on a protein in E. coli called EcFtnA, which helps manage iron within the bacteria. Researchers found that EcFtnA has a special area that slows down iron oxidation and reduces harmful byproducts, specifically demonstrating that for every 3 iron ions used, roughly 1 molecule of oxygen is produced as a waste product. This matters because understanding how EcFtnA works can help in developing better treatments for bacterial infections by targeting their iron management systems.
Who this helps: Patients with bacterial infections.
Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling.
2013
Blood
Chen Y, Aardema J, Kale S, Whichard ZL, Awomolo A +17 more
Plain English This study looked at the role of a protein called CIP4 in the production of platelets, which are vital for blood clotting. Researchers found that mice without CIP4 had fewer protrusions needed to form platelets, leading to a lower platelet count. Specifically, the number of these platelet-forming protrusions was reduced, showing that CIP4 is crucial for normal platelet production.
Who this helps: This benefits patients with low platelet counts, helping researchers understand how to improve treatments for conditions like thrombocytopenia.