ALEXANDRA M. BURGAR, M.D.

PLEASANTON, CA

Research Active
Orthopaedic Surgery - Hand Surgery NPI registered 21+ years 2 publications 1999 – 2003 NPI: 1801891932
Orthopaedic Surgery - Hand Surgery
Polymerase Chain ReactionBiomarkersImmunohistochemistryCervical VertebraeAntigensLumbar VertebraeDNA, NeoplasmMicrowavesAnthropometryFormaldehydeParaffin EmbeddingSpinal CanalFixativesMicrodissectionSex Distribution

Practice Location

4626 WILLOW RD
PLEASANTON, CA 94588-8517

Phone: (925) 463-0470

What does ALEXANDRA BURGAR research?

Dr. Burgar studies methods for analyzing tissue samples and the structural elements of the spine. She developed a new protocol for examining tissue preserved in formalin, a common preservation method, allowing researchers to better study both proteins and genetic materials within the same sample. This innovation is particularly useful in diagnosing and treating various diseases where accurate tissue analysis is crucial. Additionally, she has investigated the sizes of spine parts, known as laminas, which helps surgeons plan and perform spinal surgeries more effectively by providing essential anatomical data.

Key findings

  • Dr. Burgar's new antigen unmasking protocol preserved tissue structure better and produced higher yields of usable DNA, improving genetic testing accuracy.
  • The study of spinal laminas revealed that men generally have larger laminas than women, with the tallest lamina measuring 25.1 mm at T11.
  • Her research includes 37 adult spine samples, providing crucial data that can assist in surgical planning and interventions for spinal procedures.

Frequently asked questions

Does Dr. Burgar study tissue analysis?
Yes, she has developed a new method for analyzing tissue samples, which improves the accuracy of diagnostic tests.
What anatomical features does Dr. Burgar research?
She researches the sizes of laminas in the spine, which are important for spinal surgeries.
Is Dr. Burgar's work relevant to patients with spinal issues?
Yes, her findings about spinal anatomy can help surgeons in planning effective treatments for patients with spinal conditions.

Publications in plain English

An antigen unmasking protocol that satisfies both immunohistochemistry and subsequent PCR amplification.

2003

Pathology, research and practice

Man YG, Burgar A

Plain English
This study focused on improving a process for examining tissue samples that are preserved in formalin, which is commonly used in medical research. Researchers developed a new method to prepare these samples so that both the protein and genetic material could be studied without damaging them. Their results showed that this new protocol preserved the structure of the tissue better and produced more usable DNA for genetic testing; specifically, it resulted in higher yields and larger DNA fragments compared to traditional methods. Who this helps: This helps researchers and doctors who need accurate information from tissue samples for diagnosing and treating diseases.

PubMed

The quantitative anatomy of the laminas of the spine.

1999

Spine

Xu R, Burgar A, Ebraheim NA, Yeasting RA

Plain English
This study looked at the sizes of specific parts of the spine, called laminas, from the second cervical vertebra (C2) to the fifth lumbar vertebra (L5) using 37 adult spine samples. The researchers found that men generally had larger laminas than women, with the tallest lamina measuring 25.1 mm at T11 and the widest at L5 measuring 15.7 mm. Knowing these measurements is important because it can help doctors with spinal surgeries by providing accurate data about the anatomy of this area. Who this helps: This helps surgeons and other healthcare providers involved in spinal surgery.

PubMed

Frequent Co-Authors

Yan-Gao Man R Xu N A Ebraheim R A Yeasting

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.