DR. ALLAN M. GRANT, M.D.

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This study looked at opioid-related deaths in Nova Scotia from 2009 to 2023, focusing on trends before, during, and after the COVID-19 pandemic. Researchers found that while opioid deaths were decreasing during the pandemic, they sharply increased afterward, especially for non-prescription opioids, which rose significantly after 2021. The findings highlight the need for targeted public health strategies, especially since deaths from prescribed opioids are still high and vary across different regions in the province. Who this helps: This information benefits public health officials and policymakers.

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This study looked at how effective a specific treatment called SABR is for different types of kidney cancer, focusing on less common subtypes. Researchers analyzed data from 211 patients and found that the chance of the cancer returning locally after 5 years was very low at 1.5% for clear cell kidney cancer and 2.4% for non-clear cell types. Additionally, both groups had similar high cancer-specific survival rates of 96.4%, showing that SABR works well for these kidney cancer types. Who this helps: This information is useful for patients with uncommon kidney cancer subtypes and their doctors in making treatment decisions.

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Researchers studied a new imaging method to capture detailed pictures of brain activity using a powerful MRI machine operating at 10.5 Tesla. They found that this advanced technique improved image quality significantly by reducing motion-related blur, which resulted in an 11% increase in the clarity of brain images. This improvement allows for better understanding of how the brain works and its networks, which is important for both treatment and research. Who this helps: Patients, doctors, and researchers studying brain function.

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This study introduced a new approach to improve the measurement of magnetic fields used in MRI scans. The researchers tested this method on two types of MRI machines, one operating at a very high field strength of 10.5 Tesla and another at 7 Tesla. They found that their method produced accurate field measurements even when traditional methods failed, leading to better image quality, particularly in brain scans. This is important because it allows for clearer MRI images, which can help in diagnosing various medical conditions. Who this helps: This helps patients who need precise MRI scans, especially for brain imaging.

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This study looked at cancer screening rates among Black immigrants in the Washington, D.C. area, specifically focusing on breast, cervical, colorectal, lung, and prostate cancers. The findings showed that 70% of Black immigrant men had never been screened for colorectal or prostate cancer, while women had higher screening rates for breast (76%) and cervical (71%) cancers. The results highlight a significant gap in cancer screening for certain cancers among Black immigrant men compared to U.S.-born Blacks, indicating a need for better education and prevention efforts in this community. Who this helps: This benefits Black immigrant patients and healthcare providers.

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This study looked at how HIV care is managed for residents in care homes across the UK and Ireland. They found that of 62 residents, 92% were effectively managing their HIV and had been living with the virus for an average of 21 years. However, care approaches varied widely between locations, showing that some residents might not be getting the best possible support for their complex health needs. Who this helps: This helps care home residents living with HIV and the healthcare providers who support them.

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This study looked at a man who was born with HIV and faced serious treatment challenges, including high levels of the virus in his blood and resistance to standard HIV medications. After starting a long-acting injectable treatment along with some oral medications, his viral load dropped to undetectable levels within four weeks, and he has maintained this suppression for over a year, despite difficulties sticking to oral medications. This is important because it shows that long-acting injections can effectively manage HIV in patients with complicated cases and treatment resistance. Who this helps: This helps patients with perinatally acquired HIV, particularly those struggling with treatment adherence.

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This research studied how a specialized team, called the Advanced Cardiogenic-Shock Team (ACT), cared for patients experiencing cardiogenic shock due to heart attacks in comparison to standard care. Among 82 patients treated by the ACT, there was a 47% lower risk of dying within a year compared to 83 patients who received standard treatment (a significant difference). These findings highlight the importance of specialized, coordinated care in improving survival rates for these critically ill patients after heart attacks. Who this helps: Patients suffering from cardiogenic shock and their healthcare teams.

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This study looked at how a special type of laser therapy, called nano-pulsed laser therapy (NPLT), can help brain cells resist damage from toxic substances linked to Alzheimer's disease. The researchers discovered that brain cells treated with NPLT were better able to resist these toxins and showed increased activity of genes that help protect cells. This is important because it suggests that NPLT might be a useful non-invasive treatment to help prevent or slow down cognitive decline in Alzheimer's patients. Who this helps: Patients with Alzheimer's disease and their families.

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This study looked at AVATAR therapy, a new psychological treatment that helps people cope with distressing voices by letting them interact with a digital version of the voice. Researchers interviewed 19 participants, including some who dropped out of therapy, and found that while many faced challenges at first, most reported feeling more in control and empowered as they engaged in conversations with their digital voice. The study highlights the strong bond between therapists and participants, which helped people feel safe despite initial difficulties and can improve the therapy's effectiveness when it's used in healthcare settings. Who this helps: This benefits patients who hear distressing voices and their healthcare providers.

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This study looked at the cost-effectiveness of COVID-19 treatments and preventive measures for people who have had organ transplants, as they are at a higher risk for severe illness. Researchers reviewed 60 relevant studies and found that the cost for tixagevimab-cilgavimab as a preventive treatment was about $76,000 for each additional year of healthy life gained, while other treatments had costs ranging from $440 to $126,676 for the same benefit. Understanding these costs can help healthcare providers make better decisions about which treatments to use for transplant patients to keep them safe from COVID-19. Who this helps: This helps patients who have received organ transplants and their doctors.

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This study looked at how the 2022 formula shortage affected the feeding plans of newborns chosen by new parents. Out of 163 parents surveyed, 55% planned to exclusively breastfeed, while 37% planned to use a mix of breastmilk and formula, and only 7% intended to use formula only. While most (84%) were aware of the shortage, only 17% felt it impacted their feeding decisions, suggesting that parents prioritized other factors over the shortage when deciding how to feed their babies. Who this helps: This helps new parents and healthcare providers understand the impact of the formula shortage on feeding choices.

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This study looked at patients with head and neck cancer in Ontario who chose Medical Assistance in Dying (MAiD) from 2016 to 2022. Out of 356 patients, most were men with an average age of 72, and many chose MAiD due to poor symptom control, including pain. The use of MAiD is rising steadily, and more people in wealthier urban areas are accessing this option. Who this helps: This helps head and neck cancer patients and their families.

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This study looked at a web-based app called Summit, which is designed to help veterans safely reduce their long-term use of opioids. Out of 44 participants enrolled in the study, about one-third managed to lower their opioid doses, and most found the program acceptable, even though overall use of the app was low. These findings are important because they show that while the Summit program has potential, improvements are needed to better engage patients in reducing opioid use. Who this helps: This helps veterans seeking to lower their opioid use and manage their pain more effectively.

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This research looked at how working memory relates to a thinking bias called "jumping to conclusions," which can lead to false beliefs. The study analyzed 23 different pieces of research involving over 2,000 people and found that those with weaker working memory were more likely to jump to conclusions. Specifically, the analysis showed that people with these biases had lower working memory scores compared to those without them. Who this helps: This helps patients who experience delusions and their doctors by providing insights into how cognitive functions affect their reasoning.

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This study looked at how families experience the process of genetic testing when a child is newly diagnosed with cancer. Researchers found that many parents felt satisfied with the testing process, giving it a high satisfaction score of 98 out of 100, although some parents struggled with understanding consent due to emotional stress or lack of knowledge about genetics. Overall, clear communication from doctors is crucial to making this process easier for families. Who this helps: This benefits families of children with cancer and the doctors who support them.

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This study looked at complications related to inserting chest drains, which are used to treat different types of chest injuries, in over 100 trauma patients at Townsville University Hospital from 2020 to 2025. Researchers found that the overall complication rate was 40.2% when using traditional definitions, but dropped to 16.2% when using a more standardized method called the Clavien-Dindo classification. This matters because it highlights that many complications reported might not be serious and that a better way to classify them could lead to more accurate assessments of patient safety and care. Who this helps: This benefits doctors and trauma patients by improving treatment methods and safety assessments.

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This study looked at how to effectively change health and social systems to better support families affected by a parent's mental illness. Researchers gathered insights from 103 experts in 17 countries and found that successful system change depends on collaboration among different services, leadership support, and the ability to adapt to changes. This matters because improving these systems can lead to better outcomes for parents and their children. Who this helps: This helps families dealing with parental mental illness, health and social service providers, and policymakers.

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This study developed a new method to estimate safety risks related to radio frequency (RF) coils used in medical imaging, specifically at high magnetic fields (10.5T). The new technique showed to be safer and more reliable than traditional temperature measurements, leading to improved safety in human studies. It demonstrated a more cautious approach, which helped get regulatory approval for advanced head imaging and resulted in better quality imaging results. Who this helps: This benefits patients undergoing high-resolution imaging, as well as doctors who rely on accurate and safe MRI technology.

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This study looked at how brain stimulation can help reduce motion sickness during virtual reality experiences. Researchers found that using a specific type of brain stimulation (20 Hz vestibular brain stimulation) led to an increase in eye movement instability, which helped reduce motion sickness while participants were in VR. This is important because it shows a new, effective way to tackle motion sickness without changing VR settings, making the experience more enjoyable for users. Who this helps: This helps patients who experience motion sickness, particularly those using virtual reality technology.

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This study looked at a new way to use a very strong MRI machine (10.5 Tesla) to create detailed images of the whole brain and measure certain properties of brain tissue. The researchers found that they could get clear images and measure specific characteristics of brain tissues better than with a previous lower strength MRI machine (7 Tesla), including a 12% increase in contrast between different areas of the brain. This improved imaging technique is important because it can help doctors see fine details in the brain, which could enhance diagnosis and treatment planning for various neurological conditions. Who this helps: Patients with brain disorders and their doctors.

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This study looked at why autistic people in the UK often don’t attend cervical screening tests, which are important for preventing cervical cancer. Out of 97 participants, it found that while factors like pain and knowledge of cancer didn't directly affect attendance, poor communication with healthcare providers and negative past experiences played a significant role in making people hesitant to attend. Improving how healthcare workers communicate and support autistic individuals could help increase screening participation and possibly save lives. Who this helps: This research benefits autistic patients and healthcare providers.

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This study looked at what really matters to people when they visit a Rapid Access Addiction Medicine (RAAM) clinic in Canada for help with alcohol use. Out of nearly 160 participants, the most important aspects they agreed on included compassionate care, teamwork among staff, and prompt service. These findings can help improve addiction care by highlighting what patients value most, ultimately leading to better support for those facing alcohol use issues. Who this helps: Patients seeking help for alcohol use.

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This study looked at people living with HIV in South Africa to find out how many were secretly taking their HIV medication, known as antiretroviral therapy (ART), even though they said they weren’t. Using a urine test, researchers found that 79 out of 404 participants (20%) had been taking ART without disclosing it, and those individuals had higher immune cell counts (466 compared to 322) suggesting they were in better health. Understanding who is actually taking their medication can help healthcare providers offer better support and resources, ultimately improving the quality of care for patients. Who this helps: This helps patients with HIV and healthcare providers in South Africa.

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The study focused on how ultrasound can be used to see and evaluate the radial nerve, which can get trapped and cause pain or weakness. Researchers identified five specific spots where this entrapment might occur, and using ultrasound is a quick and affordable way to check these areas for problems. This matters because it can help doctors diagnose issues more easily and decide on effective treatments to ease patients' discomfort. Who this helps: Patients experiencing symptoms related to radial nerve entrapment.

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This study looked at using a new type of brain imaging called T*-weighted MRI at a very high magnetic field strength of 10.5 Tesla, which is more powerful than the current standard of 7 Tesla. The researchers found that the images produced at 10.5 T had a 42% better signal quality and allowed for much faster imaging without losing detail, achieving up to 12 times faster scans with advanced equipment. This is important because it could lead to clearer brain images and better understanding of brain structures, helping with diagnosis and research. Who this helps: Patients and researchers studying brain conditions.

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This study focused on improving how scientists classify and identify different types of Archaea, a group of microorganisms, by creating a new reference database called KSGP. The researchers found that using their new approach, they could increase the accuracy of taxonomic assignments by up to 4.2 times compared to existing databases, significantly enhancing our understanding of these microbes. This improvement matters because it allows for better identification of Archaea communities, which is important for ecological research and understanding microbial roles in the environment. Who this helps: This benefits researchers studying ecological and environmental microbiology.

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This study looked at different antibiotic treatments for adults with moderate-to-severe pneumonia caused by community-acquired infections. It analyzed 143 trials involving over 29,000 patients and found that no specific antibiotic regimen was significantly better than others in preventing treatment failure, hospital stays, or causing side effects. This is important because it suggests that doctors can choose between various antibiotics without worrying that one is clearly more effective than the others. Who this helps: This helps doctors determine suitable antibiotic options for their patients with pneumonia.

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This study introduced a new way to check the safety of equipment used in MRI machines, specifically focusing on multi-channel radiofrequency (RF) coils that operate at very high fields (10.5T). The researchers found that their new method, which uses computer simulations to estimate safety limits, worked better and was more reliable than the traditional method based on MRI temperature measurements. This is important because it allows for safer and more effective MRI scans on patients without exceeding safety limits. Who this helps: This benefits patients undergoing MRI scans, particularly those with advanced imaging needs.

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This study looked at how new types of pain related to Long Covid affect people's daily lives and overall well-being. Researchers found that 69.5% of Long Covid patients experienced new pain, primarily musculoskeletal pain, and 38% reported issues like post-traumatic stress disorder. Understanding these experiences is important because it can lead to better pain management and support services for those affected. Who this helps: This helps patients suffering from Long Covid and their healthcare providers.

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This study looked at the social and economic challenges faced by Canadians living with neuromuscular diseases (NMDs), which can cause muscle weakness and loss of sensation. Researchers surveyed patients and their caregivers to measure how these diseases affect education, quality of life, and employment. The findings will help shape policies and support programs for patients, highlighting the significant burden of NMDs on individuals and society. Who this helps: This benefits patients, their families, and healthcare providers.

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This study looked at when surgical residents in Canada move from junior to senior status and what factors influence that decision. It found that most programs make this transition in July of the third year of training, and those with a structured training program tend to promote residents earlier. Understanding the timing of this transition is important because it helps ensure that residents are adequately prepared for their responsibilities as senior surgeons. Who this helps: This helps surgical residents and program directors.

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This research looked at how police and healthcare workers respond to people experiencing mental distress who are not necessarily facing severe mental health issues or criminal charges. The study reviewed 41 articles and identified common issues, such as inconsistent care, negative experiences related to self-harm and intoxication, and significant gaps in emergency services. The findings show that many individuals in distress face unhelpful experiences, indicating a need for better coordination between police and health services, especially for those who are intoxicated but do not require hospitalization. Who this helps: This benefits patients experiencing mental distress and the professionals supporting them.

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This study looked at the financial challenges faced by people with neuromuscular disorders in Canada and their caregivers. They found that 70% of the 1,426 respondents experienced moderate to severe financial stress, with an average financial toxicity score of 17.2, which is lower than scores found in other chronic conditions like cancer. This matters because it highlights the significant financial burden these individuals face, especially those who are caregivers or belong to minority groups, and suggests that improving financial support and healthcare coverage could help alleviate these issues. Who this helps: This helps patients with neuromuscular disorders and their caregivers.

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This study looked at veterans with chronic overlapping pain conditions (COPCs) and how they differ from veterans with other types of chronic pain. Out of 811 veterans studied, 54% had COPCs, with common issues including chronic lower back pain (71%) and migraines (28%). Veterans with COPCs tended to be younger and more often female, and they experienced worse mental health issues, higher pain severity, and a lower quality of life compared to those without COPCs. Who this helps: This research benefits veterans, particularly those with chronic overlapping pain conditions, by highlighting their unique challenges and mental health needs.

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This study examined how a specific type of MRI (quantitative MRI) can show changes in the structure and strength of rotator cuff tendons that have been torn. Researchers found that torn tendons are much less stiff and can fail under less force compared to intact ones, and the MRI results indicated longer relaxation times, suggesting significant changes in the tendons' condition. These findings are important because they indicate that this type of MRI can help in assessing the severity of tendon injuries and could guide better treatment options. Who this helps: Patients with rotator cuff injuries.

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This research looked at the challenges faced by young caregivers under the age of 25, who often go unnoticed and unsupported in healthcare, education, and job settings. The study found that young carers need much more recognition and assistance, emphasizing three main areas: understanding that young people can take on caregiving roles, the need for resources and support for both caregivers and those they care for, and the necessity of having reliable primary healthcare available to them. This matters because improving support for young carers can lead to better health outcomes and wellbeing for both them and those they care for. Who this helps: Young caregivers and their families benefit from these improvements.

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This study looked at how 11 major autism charities in England and Wales communicate about Autistic people in their annual reports. It found that these charities often focus on the challenges and impairments associated with autism, framing themselves as the solution to these issues, while portraying government efforts as inadequate. This matters because the negative language may reinforce societal barriers for Autistic individuals instead of promoting a better understanding of their experiences and needs. Who this helps: This helps Autistic individuals and their families.

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This study looked at why people in New Zealand often ignore rules designed to prevent the spread of kauri dieback, a disease that kills kauri trees. Researchers surveyed 451 residents who had visited a kauri forest, finding that those who felt a stronger connection to the environment and were closer to the forests were more likely to follow cleaning guidelines — specifically, a 14% increase in compliance for every unit increase in their environmental awareness. Understanding these psychological factors can help develop better strategies to encourage people to take action to protect these trees. Who this helps: This helps environmental groups and policymakers aiming to protect kauri forests.

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This research looked at how people with autism experience menopause, which typically happens between ages 45 and 55. It found that many autistic individuals lack knowledge about menopause symptoms and often face severe symptoms that impact their mental health and daily life, such as increased stress at work and challenges in relationships. The study highlights the urgent need for better support and information tailored for autistic individuals about menopause to improve their healthcare experiences. Who this helps: Autistic individuals going through menopause, their families, and healthcare professionals.

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The study looked at how common chronic kidney disease (CKD) is in Jamaica and what factors might contribute to it. Researchers found that about 15% of the population studied has CKD, with nearly 7% having more severe stages of the disease. People with CKD tended to be older and had higher blood pressure and blood sugar levels, while those with more education were less likely to have the disease. Who this helps: This information benefits patients and healthcare providers in Jamaica, helping with prevention and treatment strategies.

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Researchers studied how increasing the magnetic field strength to 10.5 Tesla improves brain imaging using a technique called fMRI. They found that this higher strength provides clearer images with better detail, specifically enhancing the ability to see how different brain layers are activated during activities. The improvements lead to more precise brain activity measurements, making it easier to understand how the brain works. Who this helps: This helps patients and researchers studying brain functions and disorders.

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This study looked at ways to improve a sensory test used to detect nerve damage caused by chemotherapy, a condition known as chemotherapy-induced peripheral neuropathy (CIPN). The researchers found that testing sensitivity at the thenar eminence (the base of the thumb) was more effective than testing on the feet, showing clear differences in sensitivity between healthy individuals and those with CIPN. This new approach makes the testing quicker and easier, potentially leading to earlier and more reliable detection of nerve damage in patients undergoing chemotherapy. Who this helps: Patients undergoing chemotherapy who might develop neuropathy.

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This study looked at how different factors like age, gender, and severity of symptoms affect people’s willingness to participate in a method of assessing mental health called Experience Sampling Method (ESM) during a larger trial on psychosis. Researchers found that these factors did not significantly affect how often participants completed the assessments, but feedback from interviews highlighted that participants liked ESM because it helped them understand their mental health better. However, concerns about privacy and ease of use were barriers to engagement, leading to suggestions for improving the method. Who this helps: This helps patients with psychosis by making mental health assessments more accessible and user-friendly.

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This research looked at how community-engaged research programs in Cincinnati impact health and society over time. The study analyzed progress reports from three different programs and found that they mainly provided benefits to community health, but also had positive effects on the economy and policies. This is important because it helps create a clear way to measure and understand the lasting benefits of these community programs, making it easier to compare their outcomes in the future. Who this helps: This helps community organizations, healthcare providers, and policymakers.

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This research studied the difficulties young people with eating disorders face when eating in cafes, as well as the views of their parents and doctors. The researchers interviewed 25 participants and found six main challenges, including dealing with unexpected situations, handling difficult emotions, and managing social interactions. Understanding these challenges is crucial for creating better support and tools to help individuals with eating disorders feel more comfortable in social eating settings. Who this helps: This helps young people with eating disorders and their families.

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This study examined the financial burdens faced by people with neuromuscular diseases (NMDs) and their families. Researchers talked to 58 individuals and found that, beyond medical expenses, families also deal with hidden costs like time spent seeking support, lost job opportunities, and emotional stress, leading to significant out-of-pocket expenses. Specifically, participants reported that these factors combined created overwhelming financial and emotional pressure, which traditional cost studies don’t fully capture, highlighting the need for better healthcare support and resources. Who this helps: This benefits patients with neuromuscular diseases and their families, as well as healthcare providers looking to improve support systems.

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This study looked at a new educational program aimed at helping nursing students better support families affected by a parent's mental illness. About 80% of the students reported feeling more knowledgeable and confident in family-focused care after completing the module, and 85% were satisfied with the learning experience. This is important because it shows that training on family-focused approaches can improve healthcare practices, ultimately benefiting families dealing with mental illness. Who this helps: This helps nursing students and their future patients.

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This study looked at how effective COVID-19 vaccines were at preventing death from the virus in Jamaica between April and December 2021. Out of nearly 46,000 analyzed COVID-19 cases, only 1.5% of vaccinated people died compared to 4.1% of unvaccinated people, showing that vaccines are 68% effective at reducing the risk of death. This is important because it highlights the vaccines' role in saving lives, especially in a country where many people were still unvaccinated. Who this helps: This helps patients by demonstrating the importance of vaccination in reducing severe outcomes from COVID-19.