DR. CARL M. JOHNSON, M.D.

PADUCAH, KY

Research Active
Thoracic Surgery (Cardiothoracic Vascular Surgery) NPI registered 21+ years 50 publications 2026 – 2026 NPI: 1073519070
Wounds and InjuriesSurveys and QuestionnairesBlack or African AmericanCanadaPractice Guidelines as TopicStudents, PharmacyAlcohol DrinkingAlcoholismMass ScreeningSubstance-Related DisordersSubstance Withdrawal SyndromePatient SatisfactionBritish ColumbiaWhiteAlcohol-Related Disorders

Practice Location

2601 KENTUCKY AVE
PADUCAH, KY 42003-3826

Phone: (270) 443-5564

What does CARL JOHNSON research?

Dr. Johnson studies several key areas in healthcare, particularly the effective management and treatment of substance use disorders, including alcohol and opioid dependency. He works to streamline screening processes for alcohol use, ensuring that individuals at risk receive timely support. Additionally, he investigates new treatment modalities for severe skin conditions and evaluates the patient experience in withdrawal management programs. His research emphasizes practical applications and improvements in patient care, aiming to enhance recovery outcomes for those suffering from addiction and related health issues.

Key findings

  • 91% of participants in a new withdrawal management program rated care as 'good' or 'excellent'.
  • 53% of patients with generalized pustular psoriasis showed significant improvement with the new treatment imsidolimab within four weeks.
  • Emergency department visits for asthma dropped from 17.8% to 6% after a home visiting program in Illinois.
  • 80% of cervical cancer patients faced high financial stress during radiation treatment, with average out-of-pocket costs of $1,814 NZD.
  • 30% of patients in a wound therapy study could have transitioned to a newer treatment sooner, improving healing times.

Frequently asked questions

Does Dr. Johnson study alcohol use disorders?
Yes, he focuses on screening and treatment for individuals at risk of alcohol use disorders.
What treatments has Dr. Johnson researched for substance use disorders?
He has researched benzodiazepine treatments for opioid withdrawal and the effectiveness of new withdrawal management programs.
Is Dr. Johnson's work relevant to patients with generalized pustular psoriasis?
Yes, he studies innovative treatments like imsidolimab for this severe skin disease.
How does Dr. Johnson's work help cancer patients?
His research highlights the financial burdens that cervical cancer patients face during treatment, aiming to improve their support systems.
Are there programs Dr. Johnson has evaluated for asthma patients?
Yes, he evaluated a home visiting program in Illinois that significantly improved asthma management outcomes.

Publications in plain English

Localizing Sports-related Concussion and Characterizing Recovery Trajectories with Multimodal Brain Imaging.

2026

AJNR. American journal of neuroradiology

Bell NM, Holcomb JM, Holmes SG, Broughton MR, Johnson C +6 more

Plain English
This study looked at two high-school soccer-playing twins to understand how a recent concussion affects the brain. One twin had a concussion just 72 hours before testing, while the other did not. The concussed twin showed immediate issues like reduced brain activity and low blood flow in certain areas, while the uninjured twin had stable brain function. Over time, the concussed twin's brain function improved, indicating that brain imaging can help track recovery and make better decisions about when it's safe to return to sports. Who this helps: This research helps athletes, coaches, and doctors manage concussions more effectively.

PubMed

Organizational readiness for implementing infection control in European hospitals: insights from Coincidence Analysis.

2026

Implementation science communications

Caci L, Blum K, Johnson C, Albers B, Clack L +1 more

Plain English
This study looked at how ready hospitals in Europe are to implement strategies for preventing infections that patients may get while receiving care (known as healthcare-associated infections or HAIs). Researchers found that in 12 out of the 24 hospitals (50%), effective infection control practices were put into place; this happened mainly in complex situations where strong organizational readiness for change was necessary. However, in simpler cases, hospitals could successfully implement infection control by focusing on matching specific barriers with the right strategies instead of needing to build organizational readiness. Who this helps: This helps hospital administrators and healthcare workers who are trying to improve infection control practices.

PubMed

Identity and diet: Politics, religion, social class and vegetarian diet.

2026

Appetite

Johnson C, Schreer G

Plain English
This study looked at how people’s political views, religion, and social class relate to their attitudes towards vegetarian diets in the U.S. Researchers surveyed almost 600 participants and found that people generally connect vegetarianism with Democrats and the upper class while associating negative attitudes towards it with Republicans and Christians. This matters because understanding these connections can help develop better strategies to promote plant-based diets among different groups. Who this helps: This helps individuals and organizations that aim to encourage healthier eating habits among diverse communities.

PubMed

The Impact of Climate Vulnerability on Cancer Incidence Among U.S. Women.

2026

Cureus

Johnson C, Liao CI, Jiang RL, Tran N, Duong K +3 more

Plain English
This study looked at how climate change affects cancer rates among women in the U.S., especially focusing on racial and ethnic minority groups. Researchers found that women in states with high climate impacts saw greater increases in melanoma (2.82% annually), breast cancer (0.34% annually), and a smaller decrease in lung cancer (-0.94% annually) compared to those in low-impact states. Notably, breast cancer rates rose for Black, Hispanic, and Asian women in high-impact areas, while they declined for White women. Who this helps: This research benefits patients and healthcare providers by highlighting the need for targeted health strategies in vulnerable communities.

PubMed

Contrasting patterns of population structure in two habitat-forming kelp species in southeastern Australia.

2026

Journal of phycology

Ryder FJ, Pearman WS, Layton C, Parvizi E, Johnson C +2 more

Plain English
This study looked at two types of large seaweed, Macrocystis pyrifera and Durvillaea potatorum, to see how their populations are connected and distributed in southeastern Australia, a region facing rising sea temperatures. The researchers found that the populations of D. potatorum are more different from each other than those of M. pyrifera, and that both species are mostly connected in northeast Tasmania. This matters because the limited genetic diversity and low connectivity of these kelp populations make them more vulnerable to environmental changes, which can harm local ecosystems and fisheries. Who this helps: This research benefits environmentalists, conservationists, and the fishing industry by highlighting the risks to vital marine habitats.

PubMed

A combined experimental and theoretical study on electron induced fragmentation of methyl acetate, a model compound for side chain fragmentation and decarboxylation as pathways to main chain scission of polymethyl methacrylate as EUV lithography resist material.

2026

The Journal of chemical physics

Tafrishi R, Sequeira D, Johnson C, Ferreira da Silva F, Ingólfsson O

Plain English
This study focused on how methyl acetate, a simple chemical used in the production of plastic, breaks apart when hit by electrons. Researchers found specific energy levels at which different parts of the molecule fragment, providing crucial insights into the chemical reactions that occur, which can affect the performance of a material called polymethyl methacrylate (PMMA) used in advanced semiconductor manufacturing. Understanding these reactions helps improve the materials used in lithography, which is essential for making smaller, more efficient electronic components. Who this helps: This benefits semiconductor manufacturers and researchers developing new materials for advanced electronics.

PubMed

Age-related patterns of positive and negative self-perception of aging among middle-aged and older adults in the United States: exploring the role of education.

2026

Aging & mental health

Wang K, Dong Y, Wei W, Johnson C, Gu D

Plain English
This research looked at how middle-aged and older adults in the U.S. view aging positively or negatively and how this varies with education levels. The study found that while positive views about aging peaked in middle age and then declined, negative views about aging increased with age. Those with higher education reported lower levels of both positive and negative perceptions of aging, which suggests that education influences how people feel about getting older. Who this helps: This helps aging adults and health professionals working to support positive attitudes toward aging.

PubMed

Telephone Outreach and Skill-Based Group Education Improves Blood Pressure in Patients at a Community Health Center.

2026

Public health nursing (Boston, Mass.)

Metz C, Ashar P, Allen J, Johnson C, Haque H +5 more

Plain English
This study explored how combining phone calls with group classes can lower blood pressure in Black adults who struggle with high blood pressure. Out of 291 patients contacted, 149 engaged, 71 showed interest in classes, and 24 attended. Those who participated saw their blood pressure drop significantly, with systolic pressure going from 170.5 to 139.9 mmHg and diastolic from 97.2 to 83.2 mmHg, indicating that this approach is effective, but many patients still face challenges attending group sessions. Who this helps: This helps patients with high blood pressure, especially those in underserved communities.

PubMed

A case report of robotic-assisted repair of transabdominal diaphragmatic hernia after sternectomy with omental flap reconstruction.

2026

International journal of surgery case reports

Prasanna A, Johnson C, Lung K

Plain English
This study looked at a 70-year-old woman who developed a large hernia in her diaphragm after heart surgery that required part of her breastbone to be removed and reconstruction with a piece of her abdominal tissue. The hernia caused her breathing difficulties and chest pain, and it was successfully repaired using a robotic-assisted technique, which is a first for this type of surgical issue. This finding is important because it shows a new and effective way to fix a serious complication from heart surgery, improving recovery options for future patients. Who this helps: This helps patients recovering from complex heart surgeries.

PubMed

Telephone Outreach Is Associated With Improved Blood Pressure in Patients at an Urban Community Health Center.

2026

Journal of primary care & community health

Dalal N, Metz C, Yoon E, Allen J, Ashar P +11 more

Plain English
Researchers studied the impact of telephone outreach on controlling high blood pressure in underserved communities, focusing on Black Americans, who often struggle with hypertension. They found that patients who received phone calls with health education and support showed improved blood pressure readings, with the number of patients achieving better control increasing significantly. Specifically, the outreach efforts led to lower blood pressure levels among those engaged, highlighting the effectiveness of support in managing hypertension. Who this helps: This helps patients with high blood pressure, particularly in marginalized communities.

PubMed

Thoracostomy and thoracotomy for emergency management of pediatric pleural space pathologies.

2026

Pediatric emergency medicine practice

Johnson C, Dodington J

Plain English
This study focuses on the emergency procedures of thoracostomy and thoracotomy in children experiencing serious issues with their lungs. It highlights the importance of these procedures when doctors need to act quickly, discusses the specific reasons for performing them, and outlines potential complications. Overall, the findings emphasize that having clear guidelines and improved techniques can enhance patient safety and outcomes in critical situations. Who this helps: This information benefits doctors and emergency medical staff treating children with severe respiratory problems.

PubMed

Biomechanic characterization of normal urethra using uro-dynamic MRI during voiding.

2026

International urology and nephrology

Johnson C, Gonzalez-Pereira JP, Kounga M, Bushman W, Roldan-Alzate A

Plain English
This study used a special type of MRI to look at how the urethra works in a healthy man while he was urinating. It found that the membranous part of the urethra is the narrowest and has the highest resistance to urine flow. This research is important because it shows that this MRI method can be a safe and effective way to examine the urethra and can help us understand urinary issues better. Who this helps: This helps doctors and medical researchers studying urinary tract conditions.

PubMed

Antemortem diagnosis of metastatic endometrial adenocarcinoma using computed tomography in a Vietnamese Pot-bellied sow.

2026

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

Johnson C, Savitske B, Faccin M, Porter BF, Nagy D +1 more

Plain English
This study looked at a 13-year-old Vietnamese Pot-bellied sow that was experiencing symptoms like coughing, weight loss, and unusual vaginal discharge. Using a type of imaging called computed tomography (CT scan), researchers found tumors in the uterus and signs that the cancer had spread to her lungs, liver, and spleen. This is significant because it highlights the use of CT scans for diagnosing serious conditions like cancer in pigs, which hasn't been reported before. Who this helps: This helps veterinarians and pet owners of pot-bellied pigs.

PubMed

Impact of social risk factors on TF-CBT engagement and strategies to mitigate the impact: A qualitative analysis.

2026

PLOS mental health

Johnson C, Kiche S, Mbwayo A, Okoth DA, Nyaboke OA +3 more

Plain English
This study looked at how challenging social conditions, like poverty and poor living situations, affect people's ability to engage in trauma therapy known as TF-CBT in western Kenya. Researchers found that counselors were already finding ways to help their clients deal with these social issues using their own resources, which shows that strategies can be implemented without needing significant funding. This is important because it highlights that addressing social difficulties can improve access to mental health care and its effectiveness, especially in low-to-middle income countries. Who this helps: This helps patients and counselors dealing with mental health issues in low-resource settings.

PubMed

Minimally invasive surgery for small-bowel gastrointestinal stromal cell tumors over 5 cm: A safe and feasible approach.

2026

Surgery

Hays SB, Kuchta K, Suss NR, Ganguli S, Johnson C +4 more

Plain English
This study looked at whether minimally invasive surgery is safe and effective for removing small-bowel tumors that are 5 cm or larger. Researchers analyzed data from over 4,200 patients and found that those who had minimally invasive surgery spent less time in the hospital (4 days compared to 6 days for traditional surgery) without any increase in risks like complications or death. Since this method didn’t harm patient safety and showed benefits in recovery time, it suggests that minimally invasive surgery should be more widely used for these tumors. Who this helps: This benefits patients with small-bowel gastrointestinal stromal tumors by potentially reducing their recovery time after surgery.

PubMed

Comparative liver proteome analysis of feedlot steer calves reveals growth trait-specific pathways influenced by calving season.

2026

Journal of animal science and biotechnology

Johnson C, Singh A, Hasan Z, Islam K, Yang Z +5 more

Plain English
This study looked at the liver proteins of steer calves born in either spring or fall to understand how the season and potential for growth affect their health and development. Researchers identified over 2,100 proteins and found that the season of birth had a significant impact on protein expression, affecting immune signaling and detoxification processes in calves. These findings highlight the importance of both the time of year a calf is born and its growth potential in shaping its growth and health, which can help improve management practices in cattle farming. Who this helps: This research benefits farmers and veterinarians working with cattle.

PubMed

Sex-based effects of shock energy exposure in warfighters.

2026

Scientific reports

Sutter M, Johnson C

Plain English
This study looked at how personal armor affects male and female soldiers when exposed to shock waves, such as blasts in combat. It found that the armor, originally designed for men, does not fit women properly, which can increase the harmful effects of shock exposure by up to 78.6% for female soldiers compared to wearing no armor at all. The study showed that both men and women experience the strongest impacts when facing directly at the blast. Who this helps: This helps female soldiers who need better-fitting armor to protect them in combat.

PubMed

Genetic Dissection of Protein Content in Cowpea Using Custom-made NIRS equations and GWAS as a Model for Nutritional Breeding and Undergraduate Research Training.

2026

G3 (Bethesda, Md.)

Akinmade H, Ben-Israel S, Ryan A, Johnson C, Tharayil A +5 more

Plain English
Researchers studied the genetic factors that affect protein levels in cowpeas, a legume important for nutrition, especially in low-income areas. They developed a new method to measure protein content with near-infrared spectroscopy and identified key genetic markers linked to protein levels on several chromosomes, including chromosomes 1, 3, 7, 10, and 11. This research is important because enhancing cowpea's protein content can support better nutrition as demand for plant-based foods grows. Who this helps: This helps farmers, nutritionists, and communities that rely on cowpeas for dietary protein.

PubMed

Prognostic impact of emphysema extent on mortality and lung function decline in combined pulmonary fibrosis and emphysema: An observational cohort study.

2026

Respiratory medicine

Anderson MR, Porteous MK, Hsu WC, Lin CT, Johnson C

Plain English
This study examined the relationship between the amount of emphysema and the risk of death in patients with combined pulmonary fibrosis and emphysema (CPFE). Researchers followed 92 patients for about 8 years and found that 70% of them died during this time. Notably, those with more than 5% emphysema had a nearly four times higher chance of dying compared to those with less emphysema. Who this helps: This information benefits doctors and patients with CPFE by helping them understand the risks associated with emphysema.

PubMed

Transperineal 3D vector magnetic resonance elastography of the prostate is feasible in men with benign prostatic hyperplasia and lower urinary tract symptoms.

2026

Abdominal radiology (New York)

Johnson C, Gonzalez-Pereira JP, Grimes M, Mao L, Ricke W +3 more

Plain English
This study looked at a new imaging method called transperineal magnetic resonance elastography (pMRE) to assess the prostate in men with benign prostatic hyperplasia (BPH) and urinary issues. Researchers found that men with moderate to severe urinary symptoms had higher stiffness in the prostate tissue, which was linked to lower urine flow rates, specifically with a median International Prostate Symptom Score of 20 out of 35 indicating more severe symptoms. This matters because it shows that this imaging technique can help understand prostate health and urinary function, potentially leading to better treatment strategies. Who this helps: This helps patients with urinary issues and their doctors by providing more detailed insights into prostate health.

PubMed

"It Feels Like Another Thing Cancer Took From Me"- Exploring Cervical Cancer Patients' Experience of Financial Toxicity in Aotearoa, New Zealand.

2026

Journal of medical imaging and radiation oncology

Franklin G, Henry C, Larsen P, Johnson C

Plain English
This study looked at how cervical cancer patients in New Zealand are affected by financial stress due to medical treatment. Researchers found that many patients experience significant financial burdens, with issues arising from treatment costs, the impact on their overall financial situation, and the stress that comes with it. For example, the study identified six major themes related to the financial challenges patients face, highlighting that better information and support systems could help lessen these financial strains. Who this helps: This helps cervical cancer patients who are struggling with the costs of their treatment.

PubMed

Red cell antibody and antigen patterns in patients with sickle cell disease: A multi-center analysis.

2026

Transfusion

Covington ML, Allen ES, Chou ST, Conrad S, Evans M +14 more

Plain English
This study looked at how blood antibodies and antigens affect the treatment of 2,965 patients with sickle cell disease (SCD) at nine hospitals in the United States between 2010 and 2022. The researchers found that about 30% of patients had antibodies that could complicate their treatment, and this number varied significantly by hospital, ranging from 18% to 56%. Understanding these variations is important because it points to the need for tailored blood testing and matching protocols, rather than a one-size-fits-all approach currently used. Who this helps: This research helps doctors and blood banks manage transfusions better for sickle cell disease patients.

PubMed

Public Knowledge and Perceptions of Fentanyl Test Strips: A National Cross-Sectional Survey Informed by the Health Belief Model.

2026

Healthcare (Basel, Switzerland)

Hohmann L, Aeilts M, Johnson C, Rajic G, Sorvillo A +2 more

Plain English
This study looked at how well Americans understand and feel about fentanyl test strips (FTS), which help detect fentanyl in drugs. Among 206 participants, 81% lived in cities, and 58.5% had used recreational drugs before. The results showed that people who identified as Black or Asian felt more at risk of fentanyl exposure than White participants, and younger individuals were more confident about using FTS than older ones, suggesting that different groups have varied perceptions of this harm reduction tool. Who this helps: This research benefits both patients at risk of drug use and healthcare professionals aiming to promote safer practices.

PubMed

A mixed methods evaluation of mechanisms for facilitation in pediatric primary care.

2026

Implementation science communications

Boggs JM, Williams N, Waller CR, Pandey M, Johnson C +11 more

Plain English
This study looked at how certain strategies can help implement a brief firearm safety program in pediatric primary care during routine check-ups for children. The researchers found that a clinic's ability to adapt and change, called "adaptive reserve," did not actually influence how well the program reached families, despite previous studies suggesting it mattered. Instead, factors like building strong relationships, reminding clinicians about the program, and encouraging teamwork were more important for making the program successful. Who this helps: This helps pediatricians and healthcare facilities aiming to improve safety practices for families.

PubMed

Illicit drug supply, naloxone availability, and overdose mortality in the fentanyl era: a systematic review.

2026

Health affairs scholar

Khezri M, Holm J, Dahlen A, Johnson C, Agyabeng K +4 more

Plain English
This research paper looked at how the supply of illicit drugs, particularly fentanyl, and the availability of a lifesaving drug called naloxone affect overdose deaths. The study examined 47 previous studies and found that nearly all studies showed a clear link between increases in fentanyl in drug seizures and rising overdose deaths. It also found that programs to distribute naloxone were connected to fewer overdose deaths, although there were challenges in effectiveness during the COVID-19 pandemic. This information is crucial because understanding these factors can help improve strategies to prevent overdoses. Who this helps: This findings benefit patients at risk of overdose, healthcare providers, and public health officials.

PubMed

Remodeling-Mediated Changes in Left Ventricular Mechanics Under Settings of Chronic Pressure Overload and Exercise.

2026

Journal of biomechanical engineering

Yigamawano F, Ruiz R, Johnson C, Barnette A, Freeburg L +3 more

Plain English
This study looked at how the heart's left ventricle (the main pumping chamber) changes when it experiences long-term pressure or engages in regular exercise. Researchers found that pressure overload caused the heart muscle to become stiffer, while exercise made it more flexible; when both factors were combined, exercise helped reduce the stiffness caused by pressure. These findings highlight the importance of exercise in improving heart health and potentially predicting heart disease risk. Who this helps: This benefits patients with heart conditions and doctors treating them.

PubMed

Strengthening community-based doula and clinician partnerships through implementation and dissemination science approaches: a mixed-methods pilot study.

2026

Implementation science communications

Olson J, Chavez A, Marion E, Quinn K, Blanks G +9 more

Plain English
This study examined how community-based doulas and healthcare providers can work better together to improve birthing experiences. Researchers created a short video that highlighted the role of doulas and shared their hopes for partnership, which was viewed by both doulas and healthcare professionals. Results showed that nearly all viewers (94%) felt the video fairly represented doulas, and the collaboration scores among healthcare professionals improved significantly, from an average of 2.63 to 2.90, indicating better communication and teamwork. Who this helps: This benefits patients, especially expectant mothers, by fostering stronger support during childbirth.

PubMed

High-speed 3D single-virus tracking reveals actin-aided viral trafficking of SARS-CoV-2 on the plasma membrane.

2026

bioRxiv : the preprint server for biology

Lin Y, Lu X, Exell J, Lin H, Johnson C +1 more

Plain English
This study investigated how the SARS-CoV-2 virus moves on the surface of living cells. Researchers used advanced imaging techniques to track the virus and found that it travels in several distinct ways, including a new method along the cell's surface that happens before the virus enters the cell. They discovered that the movement of the virus is helped by structures in the cell known as actin, and this movement is linked to the presence of a receptor called ACE2. Who this helps: This research benefits scientists and doctors working on understanding and treating COVID-19.

PubMed

Evaluation of an Asthma Home Visiting Program in the State of Illinois, 2020-2023.

2026

Journal of public health management and practice : JPHMP

Patel KN, Khaium MO, Amerson N, Gustafson E, Johnson C +2 more

Plain English
This research looked at a program in Illinois that sends health workers to families with asthma to provide education and support from 2020 to 2023. It found that emergency department visits for asthma dropped from 17.8% to 6%, and there were no hospitalizations during this time. The program not only improved patients' quality of life—like increasing well-controlled asthma rates from 24.8% to 45.4%—but also saved $1.4 million, making it a cost-effective solution. Who this helps: This benefits patients with asthma and their families.

PubMed

Impact and Durability of a Skills-Lab Session on Pharmacy Student Knowledge and Perceptions of Substance Use Disorders and Harm Reduction.

2026

Journal of the American College of Clinical Pharmacy : JACCP

Johnson C, Whitworth M, Teeter BS

Plain English
This study looked at how a special training session for pharmacy students improved their understanding and attitudes toward substance use disorders (SUDs) and harm reduction strategies like naloxone use. Before the training, students scored an average of 7.9 on the Opioid Overdose Knowledge Scale (OOKS), which improved to 11.5 immediately after the training. However, a year later, while their overall knowledge decreased slightly, three areas of their perceptions about drug users worsened. This matters because effective training is essential for pharmacy students to confidently help patients struggling with substance abuse. Who this helps: Patients with substance use disorders and the pharmacists who support them.

PubMed

Understanding the Factors Influencing Black Pharm.D. Student Engagement in Research: A Multi-Institutional Qualitative Study.

2026

Journal of the American College of Clinical Pharmacy : JACCP

Whitner C, Afolabi T, Maignan F, Johnson C, Robinson D +5 more

Plain English
This study looked at what makes it easier or harder for Black pharmacy students to get involved in research while in school. Researchers interviewed 29 students and found that many felt limited by factors like not knowing enough about research opportunities, feeling intimidated, and not seeing enough Black faculty in research roles. On the positive side, having faculty who understood their cultural background and better communication about research opportunities made it easier for these students to participate. Who this helps: This benefits Black pharmacy students seeking to engage in research activities during their studies.

PubMed

Sequential buckling in fluid-filled cylindrical shells.

2026

Communications physics

Jain S, Box F, Quinn M, Johnson C, Pihler-Puzović D

Plain English
This study looked at how liquid-filled cylindrical containers, like beverage cans, behave when they are compressed. The researchers discovered that at a certain level of pressure, these containers start to buckle in specific patterns—like rings around the can—rather than just collapsing all at once. This finding is important because it helps us understand how materials react under pressure, which can improve the design and safety of various cylindrical structures used in everyday life and industry. Who this helps: This helps engineers and manufacturers working with cylindrical containers and structures.

PubMed

Epidemiology of open and closed diastemata in equine cheek teeth and associations with periodontal pathology.

2026

Veterinary research communications

Mata F, Johnson C

Plain English
This study looked at a dental problem called diastemata (gaps between teeth) in horse cheek teeth and how it relates to periodontal disease. Researchers examined 50 horse heads and found a total of 317 gaps, with 63.1% of them being open and 36.9% closed. They discovered that 62.5% of the diastemata were linked to periodontal disease, with open gaps showing more severe disease, particularly in older horses and mares. Who this helps: This research benefits horse owners and veterinarians by highlighting the importance of early dental check-ups for better horse health.

PubMed

Antibiotic Stewardship at transitions of care: identifying opportunities for antibiotic optimization.

2026

Antimicrobial stewardship & healthcare epidemiology : ASHE

Johnson C, Thomas J, Valanejad S, Medler C

Plain English
This study looked at how often people with infections like respiratory, urinary tract, or skin infections receive the best oral antibiotics when their care transitions, such as moving from hospital to home. They found that 62.5% of patients were given the right antibiotics during these transitions, showing that there is a chance to improve how antibiotics are managed in these situations. This is important because better antibiotic use can help prevent resistance and improve patient outcomes. Who this helps: Patients receiving care for infections.

PubMed

Building engagement in healthy aging outcomes research with older women with lived experience of incarceration.

2026

Journal of clinical and translational science

Anderson S, Covington LA, Davis S, Emerson A, Cox Hayley D +10 more

Plain English
This research focused on older women over 50 who have been incarcerated and how their health needs related to aging are often ignored. The study involved creating a network from November 2024 to June 2025, where these women, along with doctors and community leaders, worked together to discuss their health concerns and priorities. The goal was to ensure that their voices are included in health research, leading to better support and resources for their unique challenges after incarceration. Who this helps: This benefits older women with past incarceration, healthcare providers, and researchers looking for ways to improve health outcomes in this group.

PubMed

Financial Toxicity in Cervical Cancer Patients Undergoing Radical Treatment With External Beam Radiation and Brachytherapy at a Tertiary New Zealand Radiation Oncology Centre.

2026

Journal of medical imaging and radiation oncology

Franklin G, Larsen P, Henry C, Johnson C

Plain English
This study looked at the financial challenges faced by cervical cancer patients receiving radiation treatment in New Zealand. It found that 80% of these patients experienced high financial stress, with average out-of-pocket costs of $1,814 NZD, compared to just $264 NZD for other types of cancer patients. These findings highlight the urgent need to address the financial strains on these patients to ensure they receive the support they need during treatment. Who this helps: This helps cervical cancer patients who face significant financial burdens during their treatment.

PubMed

Efficacy and Safety of Imsidolimab for Generalized Pustular Psoriasis.

2026

NEJM evidence

Smieszek S, Przychodzen B, Tyner C, Johnson C, Bushman M +19 more

Plain English
This study researched the effectiveness and safety of a new treatment called imsidolimab for people with generalized pustular psoriasis (GPP), a severe skin disease. In the first part of the study, 53% of patients receiving imsidolimab showed significant improvement within four weeks, compared to only 13% of those who received a placebo. The follow-up showed that patients could safely continue treatment without serious side effects for up to two years. Who this helps: This research benefits patients with generalized pustular psoriasis who need new treatment options.

PubMed

Clinician decision-making for transitioning to single-use negative pressure wound therapy: analysis of real-world practice in an acute setting.

2026

Journal of wound care

Johnson C, Spitzer M, Berry S, Minton J

Plain English
This study looked at how doctors decide when to switch patients from traditional wound therapy (tNPWT) to a newer single-use system (sNPWT) in a hospital. It found that out of 27 patients, 30% could have moved to the new system sooner, which could help patients heal faster and leave the hospital earlier without affecting their recovery. Utilizing the single-use system more often could lead to better patient experiences and more efficient use of hospital resources. Who this helps: Patients with hard-to-heal wounds.

PubMed

Patient experiences and perceived efficacy of a newly implemented hospital-based withdrawal management unit in Vancouver, Canada: findings from the Road to Recovery evaluation.

2026

Addiction science & clinical practice

Roberge S, Nolan S, Johnson C, Dickhout P, Abramowich A +8 more

Plain English
This study looked at how patients experienced a new withdrawal management unit for substance use disorders in Vancouver, Canada. Out of 87 participants, 91% rated the quality of care as "good" or "excellent," and 67% accessed services within 48 hours. This matters because it shows that the program effectively supports patients in their recovery journey, especially through respectful staff interactions and integration of cultural and peer support. Who this helps: This benefits patients with substance use disorders and healthcare providers working in addiction treatment.

PubMed

Us.

2026

Drug and alcohol dependence reports

Wong A, Nolan S, Bach P, Janssen RM, De Wolfe TJ +7 more

Plain English
This study looked at how safely and effectively a short-term treatment using benzodiazepines could help individuals with opioid use disorder who are experiencing unusual withdrawal symptoms due to high levels of fentanyl in street drugs. Among 18 participants, who were mostly around 30 years old and included many who were unhoused, they found that the treatment was well-tolerated with no negative side effects reported. Additionally, after treatment, most participants continued their opioid medication for over a month, which is important for ongoing recovery. Who this helps: This benefits patients struggling with opioid addiction and their healthcare providers.

PubMed

Genotype-phenotype modeling of light ecotypes inreveals genomic signatures of ecotypic divergence.

2026

bioRxiv : the preprint server for biology

Brenner E, Vang C, Johnson C, Ravi J

Plain English
This study looked at how certain marine bacteria, known as cyanobacteria, adapt to different light conditions by analyzing their genetic information. Researchers examined around 1,000 genomes and found that these bacteria can be accurately categorized into high-light and low-light types based on their genes, achieving nearly perfect predictions (with a 0.86 to 1.00 accuracy rate). Understanding these genetic differences is important because it helps us learn how these organisms survive in various ocean environments and can inform future research on their use in biotechnology. Who this helps: This benefits researchers and scientists working with marine biology and biotechnology.

PubMed

Patient Perspectives on Cardiac Gene Therapy: A Survey of Knowledge, Attitudes, and Educational Needs.

2026

Journal of cardiac failure

Silver E, Taub A, Bui V, Ruf G, Johnson C +7 more

PubMed

Screening for high-risk drinking and alcohol use disorder: update of the 2023 national clinical practice guideline.

2026

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

Wood E, Wong SC, Corace K, Martell D, Barker B +15 more

Plain English
This research updated guidelines for screening people at risk of drinking too much alcohol and developing alcohol use disorder in Canada. The new recommendations include asking all patients about their alcohol use and providing support to those who drink more than what's considered safe, aiming to make the screening process quicker and easier. This matters because it helps identify and address alcohol-related health issues more efficiently, potentially benefiting many individuals who may not realize their drinking poses risks. Who this helps: Patients at risk of harmful alcohol use.

PubMed

Is there a correlation between season and weather patterns on trauma admissions?

2026

Injury

Lewis J, Liu AM, Johnson C, Bukowski J, Chrostowski E +3 more

Plain English
This study looked at how weather conditions, like temperature and humidity, impact the number and seriousness of trauma cases at a major hospital over three years. Researchers found that warmer temperatures led to more trauma cases, with a total of 8,699 patients involved. Specifically, injuries from car accidents and falls increased with higher temperatures, while rainy and humid conditions tended to lower the number of trauma cases. This is important because it helps hospitals plan better and allocate resources during times when they are likely to see more injuries, especially in summer months. Who this helps: This benefits hospitals and emergency services by improving resource management.

PubMed

In vitro release testing of levonorgestrel intrauterine systems: Correlation of accelerated release rates in organic/aqueous release media to Hansen Solubility Parameters.

2026

International journal of pharmaceutics

Zaman RU, Johnson C, Smith W, Wang Y, Zhong Z +2 more

Plain English
This research focused on the release rates of the levonorgestrel intrauterine system (LNG-IUS), a long-lasting birth control method. The study found that when using specific solvents, the drug release could be up to nine times faster than traditional testing methods. This is important because it could lead to quicker and more efficient testing for new versions of LNG-IUS, potentially advancing the availability of affordable options for patients. Who this helps: Patients seeking effective and economical birth control methods.

PubMed

Synergy and antagonism in a genome-scale model of metabolic hijacking by bacteriophages.

2026

Science advances

Rozum JC, Sineath W, Bohutskyi P, Quenneville J, Kim DN +8 more

Plain English
This study looked at how certain genes from bacteriophages, which are viruses that infect bacteria, change the way bacteria like MED4 use nutrients. The researchers found that 17 of these genes directly affect over 30% of the bacteria's metabolic processes, influencing important functions like how they fix carbon and produce energy. Understanding these interactions is crucial because it shows how bacteriophages can dramatically change bacterial behavior and growth, which could help in developing new treatments for bacterial infections. Who this helps: This research benefits scientists working on bacterial infections and potential therapeutic uses of bacteriophages.

PubMed

UV irradiation alters TFAM binding specificity and compaction of DNA.

2026

eLife

King DE, Beard EE, Satusky MJ, George A, Ryde I +10 more

Plain English
This study looked at how a protein called TFAM interacts with mitochondrial DNA when cells are exposed to UV light, which causes DNA damage. Researchers found that after UV exposure, the amount of TFAM increased and it bound more tightly to damaged DNA, but this did not actually protect the DNA from getting worse over time. This matters because it suggests that while TFAM helps to organize damaged DNA, it doesn't prevent further damage and could play a role in removing damaged DNA from cells. Who this helps: This helps researchers and doctors working on treatments related to mitochondrial damage and diseases.

PubMed

The virus entry inhibitor ARN-75039 provides therapeutic protection against Lassa virus infection in guinea pigs.

2026

Science translational medicine

Eudy E, Woodburn D, Reeder R, Cooper K, Hart R +10 more

Plain English
This study looked at a new drug called ARN-75039, which could help protect against Lassa virus infection in guinea pigs. Researchers found that treating the guinea pigs with ARN-75039 either three or seven days after exposure to the virus completely prevented serious illness at low doses of the drug (3.75 mg/kg or 7.5 mg/kg). This matters because there are currently no approved vaccines for Lassa fever, and this drug could offer a promising treatment option. Who this helps: This helps patients at risk of Lassa fever and doctors looking for effective treatments.

PubMed

Best practices for interpretation and management of common laboratory abnormalities in dermatology. Part II. Complete blood count and infectious diseases.

2026

Journal of the American Academy of Dermatology

Overholt C, Bissenas A, Pastore L, Farsi M, Liu V +5 more

Plain English
This article examines important blood tests and infection-related evaluations that dermatologists often use to care for their patients. It found that understanding the results of these tests, like those for tuberculosis and HIV, is crucial for deciding when a patient needs specialized care. For instance, abnormal results can signify serious health issues, and knowing how to interpret these can improve patient outcomes. Who this helps: This benefits dermatology patients who may have underlying health concerns.

PubMed

Best practices for interpretation and management of common laboratory abnormalities in dermatology. Part I. Lipids, liver enzymes, and renal function.

2026

Journal of the American Academy of Dermatology

Bissenas A, Overholt C, Farsi M, Pastore L, Liu V +5 more

Plain English
This study looks at how dermatologists can better interpret and manage laboratory tests related to lipids (fats in the blood), liver enzymes, and kidney function. It highlights the importance of understanding these tests, knowing when to refer patients to specialists, and recognizing urgent medical situations that involve abnormal results. This is crucial because accurate interpretation of these tests can lead to better diagnoses and treatments for patients with skin concerns. Who this helps: Dermatologists and their patients.

PubMed

Frequent Co-Authors

Seonaid Nolan Piper Dickhout Juan Pablo Gonzalez-Pereira Caroline Metz Jada Allen Perisa Ashar Huda Haque Anna Tharakan Bradi B Granger

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.