Phase II trial of 5-fluorouracil, folinic acid and recombinant alpha-2a-interferon in patients with advanced colorectal cancer.
1999Anti-cancer drugs
Ravandi F, Rytting ME, Osmon C, Braud EL, Roach RW +4 more
Plain English
Researchers studied a treatment combining 5-fluorouracil, folinic acid, and a drug called recombinant alpha-2a-interferon in patients with advanced colorectal cancer. They found that this combination had an overall response rate of 29%, with patients surviving a median of 15.5 months after starting treatment. However, the combination caused more side effects and was no more effective than using 5-fluorouracil with just one of the other drugs.
Who this helps: This information helps doctors in their treatment planning for patients with advanced colorectal cancer.