CHRISTOPHER J. DRESSEL JR., M.D.

SCRANTON, PA

Research Active
Internal Medicine - Interventional Cardiology NPI registered 21+ years 7 publications 2001 – 2020 NPI: 1598760928
Cells, CulturedCell ProliferationAntineoplastic AgentsApoptosisHot TemperatureDose-Response Relationship, DrugMolecular Dynamics SimulationPolymersDrug Evaluation, PreclinicalStereoisomerismThiophenesPhase TransitionAlkanesEntropyTransition Temperature

Practice Location

746 JEFFERSON AVE
SCRANTON, PA 18510-1639

Phone: (570) 342-1776

What does CHRISTOPHER DRESSEL research?

Dr. Dressel's research primarily investigates the unique properties and behaviors of liquid crystals, which are materials that can flow like a liquid but have some properties of solids. He explores how different molecular arrangements, particularly the shapes and interactions of these molecules, can lead to interesting phenomena like chirality (the property of being non-superimposable on its mirror image) and structural transitions. Additionally, he studies how certain compounds, such as derivatives of tormentic acid, can induce cancer cell death, making strides toward better cancer therapies. His findings are crucial for enhancing technologies like displays and sensors, as well as for deepening our understanding of materials and their behaviors.

Key findings

  • In 2020, Dressel's research demonstrated that adjusting the size of cycloaliphatic rings can yield three distinct structures in liquid crystalline phases, important for future technology applications.
  • The 2018 study revealed that the smectic-Q phase of liquid crystals could form unique twisted structures even in achiral materials, suggesting new avenues for optical technology development.
  • In 2015, findings showed that a special liquid could behave like a mix of two distinct twisted liquids under specific conditions, which may inform future materials science advancements.
  • A 2014 study detailed how achiral molecules can self-organize into chiral structures at high temperatures, enhancing our knowledge of chirality and its relevance to natural processes.
  • Dressel's 2012 research identified a derivative of tormentic acid that significantly promoted cancer cell death, pointing toward potential new cancer treatments.

Frequently asked questions

Does Dr. Dressel study liquid crystals?
Yes, Dr. Dressel's research focuses extensively on the properties and behaviors of liquid crystals, including their molecular structures and applications.
What diseases or conditions are related to Dr. Dressel's research?
His work has implications for cancer treatment, particularly through the study of compounds that can promote cancer cell death.
Is Dr. Dressel's work relevant to technology?
Yes, his findings on liquid crystals are crucial for technological advancements in displays, sensors, and optical devices.
What techniques does Dr. Dressel use in his research?
He employs various experimental methods to study molecular structures, phase behaviors, and the effects of different compounds on cell viability.
How does Dr. Dressel's research impact patients?
His efforts to discover effective cancer treatments can lead to improved outcomes for patients, alongside advancements in material technologies that may enhance everyday devices.

Publications in plain English

Controlling spontaneous mirror symmetry breaking in cubic liquid crystalline phases by the cycloaliphatic ring size.

2020

Chemical communications (Cambridge, England)

Reppe T, Dressel C, Poppe S, Tschierske C

Plain English
This study looked at new materials made from rod-like molecules with special shapes to create different liquid crystal phases. The researchers found that by changing the size of certain rings in the molecules, they could create three distinct structures, including one with a twist that occurs when the angles between the molecules are between 8.6° and 9.5°. Understanding how to control these phases is important because it could lead to advancements in technology that use liquid crystals, like displays and sensors. Who this helps: This helps materials scientists and engineers working on liquid crystal technologies.

PubMed

The Solution of the Puzzle of Smectic-Q: The Phase Structure and the Origin of Spontaneous Chirality.

2018

Angewandte Chemie (International ed. in English)

Lu H, Zeng X, Ungar G, Dressel C, Tschierske C

Plain English
This study focused on understanding a special phase of liquid crystals known as smectic-Q (SmQ), which has puzzled scientists since its discovery in 1983. Researchers found that SmQ forms a unique structure made of twisted columns with special junctions, and it can occur even in materials that do not have chiral properties, suggesting a new way these structures can emerge. These findings are important because they can lead to new materials for technologies like circularly polarized light emitters, which can work more efficiently without needing complex arrangements. Who this helps: This benefits researchers and manufacturers working on advanced optical technologies.

PubMed

Spontaneous mirror symmetry breaking in a re-entrant isotropic liquid.

2015

Chemical communications (Cambridge, England)

Dressel C, Weissflog W, Tschierske C

Plain English
This study looked at a special type of liquid that changes its structure under certain conditions. Researchers found that when this liquid was in a specific state, it behaved like a mix of two separate liquids that each have a distinctive twist, or chirality. The research is important because understanding these unique liquid behaviors can lead to advancements in materials science and possibly new technologies. Who this helps: This benefits scientists and researchers working on materials and liquid technologies.

PubMed

Dynamic mirror-symmetry breaking in bicontinuous cubic phases.

2014

Angewandte Chemie (International ed. in English)

Dressel C, Liu F, Prehm M, Zeng X, Ungar G +1 more

Plain English
This research studied how certain molecules, which normally don't have a specific shape (called achiral), can still develop a preference for a certain twist or orientation when they form structured groups. Researchers found that in a specific type of structure called the Im3̅m cubic phase, these molecules showed a clear preference for a chiral twist, while in another structure, called Ia3̅d, they did not. This discovery helps explain why some materials have unique properties and how they can change between different structures. Who this helps: This helps scientists and engineers working with liquid crystals and materials used in displays or sensors.

PubMed

Chiral self-sorting and amplification in isotropic liquids of achiral molecules.

2014

Nature chemistry

Dressel C, Reppe T, Prehm M, Brautzsch M, Tschierske C

Plain English
This study looked at how chiral (mirror-image) forms of molecules can form organized structures from achiral (non-mirror-image) molecules in liquids, even at high temperatures around 200 °C. The researchers found that these molecules can separate into two distinct chiral liquid phases, demonstrating a strong amplification of chiral properties. This discovery is important because it enhances our understanding of how chirality can develop in natural processes, potentially influencing research on life's origins. Who this helps: This benefits scientists studying molecular chemistry and the origins of life.

PubMed

Tormentic acid derivatives: synthesis and apoptotic activity.

2012

European journal of medicinal chemistry

Csuk R, Siewert B, Dressel C, Schäfer R

Plain English
This research studied different versions of tormentic acid and their ability to kill cancer cells. One particular version, called dichloroacetate, showed strong effects in promoting cancer cell death through specific mechanisms, which were confirmed by various laboratory tests. This matters because finding effective new treatments for cancer can lead to better outcomes for patients. Who this helps: This helps cancer patients looking for more effective treatment options.

PubMed

Strangulation of the duodenum by the uterus during late pregnancy in two cows.

2001

Veterinary journal (London, England : 1997)

Koller U, Lischer C, Geyer H, Dressel C, Braun U

Plain English
This study looked at two pregnant cows that developed a serious blockage in their intestines because the weight of their uterus pressed against part of their digestive system. The problem happened because their intestines were not properly attached, making it easier for the uterus to cause a blockage. After surgery to fix the blockage, both cows recovered well and gave birth normally a couple of months later. Who this helps: This research benefits veterinarians and farmers by highlighting a rare but important complication in pregnant cows.

PubMed

Frequent Co-Authors

Carsten Tschierske Tino Reppe Xiangbing Zeng Goran Ungar Marko Prehm Silvio Poppe Huanjun Lu Wolfgang Weissflog Marcel Brautzsch Feng Liu

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.