Dr. Sundstrom studies how various medical conditions and treatments affect both human and animal health. He examines how premenstrual dysphoric disorder (PMDD) impacts women with epilepsy and how antiepileptic medications can exacerbate symptoms. He also investigates surgical methods for correcting bunion deformities in the feet and evaluates treatments like vitamin C and baking soda on the performance of racing greyhounds. His work seeks to find better management strategies and improve outcomes for patients and their healthcare providers.
Key findings
Women with epilepsy often face greater severity of PMDD symptoms, especially those with right-sided epilepsy and on carbamazepine, indicating a need for specialized management.
In a study of 57 patients, the modified Lapidus arthrodesis method maintained correction of bunion deformities better, with an average loss of just 1.08 degrees compared to 2.55 degrees for the closing base wedge osteotomy.
Racing greyhounds given vitamin C ran an average of 0.2 seconds slower than without it, suggesting that it may hinder rather than help their performance.
Baking soda treatment in racing greyhounds did not improve sprint times or lactate levels, indicating it may not benefit racing performance as previously thought.
Low doses of phorbol ester made glioma brain cancer cells less susceptible to immune attacks, highlighting potential avenues for enhancing cancer therapy efficacy.
Frequently asked questions
Does Dr. Sundstrom study premenstrual dysphoric disorder?
Yes, he studies how PMDD affects women with epilepsy and its relationship with antiepileptic medications.
What treatments has Dr. Sundstrom researched for bunions?
He has researched surgical methods, comparing modified Lapidus arthrodesis and closing base wedge osteotomies for bunion correction.
Is Dr. Sundstrom's work relevant to racing greyhounds?
Yes, he studies the effects of nutritional supplements and treatments like vitamin C and baking soda on their racing performance.
What types of cancer research does Dr. Sundstrom conduct?
He has researched brain cancer, focusing on how specific chemicals affect tumor cells' sensitivity to immune therapies.
Who can benefit from Dr. Sundstrom's research?
Women with epilepsy, patients with bunion deformities, dog trainers, and brain cancer patients can all benefit from his findings.
Publications in plain English
Premenstrual dysphoric disorder in women with epilepsy: relationships to potential epileptic, antiepileptic drug, and reproductive endocrine factors.
2011
Epilepsy & behavior : E&B
Herzog AG, Smithson SD, Fowler KM, Krishnamurthy KB, Sundstrom D +7 more
Plain English This study looked at how premenstrual dysphoric disorder (PMDD) affects women with epilepsy compared to women without epilepsy. The researchers found that women with epilepsy often have more severe PMDD symptoms, especially if they have certain types of epilepsy or specific hormone levels. For instance, those with right-sided epilepsy experienced greater PMDD severity, and symptoms were linked to their antiepileptic medications, with carbamazepine showing a direct correlation with more severe symptoms.
Who this helps: This helps women with epilepsy and their healthcare providers understand the relationship between epilepsy and PMDD for better management of both conditions.
Maintenance of correction of first metatarsal closing base wedge osteotomies versus modified Lapidus arthrodesis for moderate to severe hallux valgus deformity.
2007
The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
Haas Z, Hamilton G, Sundstrom D, Ford L
Plain English This study looked at two surgical methods for correcting a foot problem called hallux valgus, which is commonly known as a bunion. Researchers reviewed 57 patients and found that the modified Lapidus arthrodesis method maintained the correction better than the closing base wedge osteotomy method, with an average correction loss of just 1.08 degrees compared to 2.55 degrees for the latter. This is important because it means that patients undergoing the modified Lapidus procedure may have better long-term results after surgery.
Who this helps: This benefits patients with moderate to severe bunion deformities.
Supplemental vitamin C appears to slow racing greyhounds.
2002
The Journal of nutrition
Marshall RJ, Scott KC, Hill RC, Lewis DD, Sundstrom D +2 more
Plain English This study looked at whether giving vitamin C to racing greyhounds would help improve their performance and reduce the oxidative stress from intense exercise. Researchers found that while blood levels of vitamin C increased when given before racing, the dogs actually ran about 0.2 seconds slower—equivalent to finishing 3 meters behind their best time—when they received the vitamin. This matters because it suggests that vitamin C may not be beneficial for greyhounds' racing performance, and could even be counterproductive.
Who this helps: This helps dog trainers and owners who are looking to optimize their pets' racing performance.
Effect of acute induced metabolic alkalosis on the acid/base responses to sprint exercise of six racing greyhounds.
1996
Research in veterinary science
Holloway SA, Sundstrom D, Senior DF
Plain English This study looked at how giving greyhound dogs a baking soda drink (sodium bicarbonate) affected their body’s response during sprint races. The dogs raced four times, and their results showed that there was no difference in how fast they ran or in their lactate levels (a measure of exercise intensity) whether they received baking soda or a control solution. However, after the baking soda treatment, the dogs had lower levels of chloride in their blood.
Who this helps: This research can help improve understanding for dog trainers and veterinarians about the effects of different treatments on racing performance and recovery.
Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity.
1990
Journal of neurosurgery
Maleci A, Alterman RL, Sundstrom D, Kornblith PL, Moskal JR
Plain English This study looked at how a chemical called phorbol ester affects brain cancer cells' sensitivity to immune cells that can kill them. Researchers found that when they treated a specific glioma cell line (SNB-19) with low amounts of phorbol ester, the cancer cells became less vulnerable to being killed by these immune cells, and this effect could be reversed. Understanding this interaction is important because it may lead to better ways to enhance the effectiveness of immune therapies against brain cancer.
Who this helps: This helps patients with brain cancer and the doctors treating them.
Andrew G Herzog Sarah D Smithson Kristen M Fowler Kaarkhuzali B Krishnamurthy Laura A Kalayjian Christi N Heck Sandra Oviedo Guadalupe Correl-Leyva Eduardo Garcia Katherine A Gleason
Physician data sourced from the
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Publication data from
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Plain-English summaries generated by AI.
Not medical advice.