Does Dr. Krikorian study schizophrenia?

Yes, Dr. Krikorian's research investigates how genetic variations linked to schizophrenia affect brain development.

What treatments has Dr. Krikorian researched?

While his work primarily focuses on understanding genetic influences on the brain, this research can inform potential treatments for neurodevelopmental disorders.

Is Dr. Krikorian's work relevant to autism?

Yes, his studies on the 22q11.2 gene region are directly relevant, as they explore genetic factors that may increase the risk of autism.

ENRIQUE KRIKORIAN, M.D.

HIALEAH, FL

Research Active

Orthopaedic Surgery - Sports Medicine NPI registered 21+ years 1 publication 2017 – 2017 NPI: 1689677015

Orthopaedic Surgery - Sports Medicine

BrainDNA Copy Number VariationsOrgan SizeBrain MappingGene RearrangementGene Dosage22q11 Deletion Syndrome

Practice Location

7100 W 20TH AVE
HIALEAH, FL 33016-1897

Phone: (305) 822-0401

What does ENRIQUE KRIKORIAN research?

Dr. Krikorian studies the impact of genetic variations in the 22q11.2 region on the brain’s structure. This includes looking at how different numbers of gene copies can lead to changes in brain features among individuals. Specifically, he examines patients with deletions or duplications of genetic material in this area, investigating conditions such as schizophrenia and autism. By mapping these gene dosage effects, his research helps shed light on how genetic differences contribute to neurodevelopmental issues, aiding in better diagnosis and treatment.

Key findings

Individuals with gene deletions in the 22q11.2 region showed thicker cortices compared to those with normal gene copies.
Patients with gene duplications exhibited larger brain volume and surface area but had thinner cortices, indicating distinct structural changes.
The study included 143 participants, providing a substantial dataset to analyze the relationship between gene dosage and brain morphology.

Frequently asked questions

Does Dr. Krikorian study schizophrenia?: Yes, Dr. Krikorian's research investigates how genetic variations linked to schizophrenia affect brain development.
What treatments has Dr. Krikorian researched?: While his work primarily focuses on understanding genetic influences on the brain, this research can inform potential treatments for neurodevelopmental disorders.
Is Dr. Krikorian's work relevant to autism?: Yes, his studies on the 22q11.2 gene region are directly relevant, as they explore genetic factors that may increase the risk of autism.

Publications in plain English

Mapping 22q11.2 Gene Dosage Effects on Brain Morphometry.

2017

The Journal of neuroscience : the official journal of the Society for Neuroscience

Lin A, Ching CRK, Vajdi A, Sun D, Jonas RK +9 more

Plain English
This study examined how different copies of genes in the 22q11.2 region of the genome affect brain structure in 143 people, including those with deletions or duplications of this genetic material. Researchers found that those with deletions had thicker cortices, while those with duplications had larger brain volume and surface area but thinner cortices. Understanding these differences is important because they highlight how genetic variations can lead to distinct brain development patterns, which may help explain risks for conditions like schizophrenia and autism. Who this helps: This benefits patients with neurodevelopmental disorders and their healthcare providers.

PubMed

Frequent Co-Authors

Amy Lin Christopher R K Ching Ariana Vajdi Daqiang Sun Rachel K Jonas Maria Jalbrzikowski Leila Kushan-Wells Laura Pacheco Hansen Boris Gutman Deepika Dokoru

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.