Dr. Munoz studies a range of health issues that significantly affect vulnerable populations, including posttraumatic stress disorder (PTSD), cancer care among Latinos, and neurodegenerative diseases like X-linked dystonia parkinsonism (XDP). His research emphasizes the importance of communication in treatment options for PTSD patients to ensure they understand their therapies. He also investigates the various social and healthcare factors contributing to cancer disparities in the Latino community, identifying ways to improve treatment access and outcomes. Additionally, Dr. Munoz explores the relationship between immune responses and delirium in older patients, particularly those hospitalized with COVID-19, to find better treatment methods for this condition.
Key findings
In his PTSD study, less than half of the 887 participants remembered how effective their assigned treatments were, and only about one in three could describe their treatment correctly.
The cancer disparities research identified multiple factors, including social, economic, and healthcare-related issues, that contribute to higher cancer rates among Latinos.
For older COVID-19 patients experiencing delirium, persistent changes in immune gene expression were observed, with certain inflammation-related genes increasing over time.
The CancerClarity app developed in his study helps simplify cancer data for community cancer centers, making it easier for patients to understand statistics about cancer rates and outcomes.
In his research on XDP, longer genetic repeat sequences were linked to earlier disease onset, indicating potential new targets for therapies that could slow neurodegeneration.
Frequently asked questions
Does Dr. Munoz study PTSD?
Yes, Dr. Munoz studies posttraumatic stress disorder (PTSD) and how well patients recall their treatment information, which impacts their outcomes.
What does Dr. Munoz's research on cancer focus on?
He focuses on the disparities in cancer rates and outcomes among Latino patients, exploring the social and healthcare factors that contribute to these issues.
Is Dr. Munoz's work relevant to older patients with delirium?
Yes, his research examines how immune system responses affect delirium in older patients, particularly those hospitalized with COVID-19.
What treatments has Dr. Munoz researched for neurodegenerative diseases?
He has researched X-linked dystonia parkinsonism (XDP) and identified genetic elements that could be targeted for potential new treatments to slow down or prevent neurodegeneration.
How can Dr. Munoz's work help patients and communities?
His work aims to improve treatment understanding for individual patients and address broader cancer care disparities, ultimately enhancing healthcare access and outcomes for marginalized communities.
Publications in plain English
Recall of posttraumatic stress disorder treatment information.
2026
Journal of traumatic stress
Larsen SE, Grubbs KM, Grau P, Munoz E, Hamblen J
Plain English This research studied how well patients with posttraumatic stress disorder (PTSD) remember information about their treatment options. Out of 887 participants, less than half remembered how effective the treatments were, and only about one in three could correctly describe the treatment they were assigned. This matters because better recall can lead to better treatment results, highlighting the need for clearer communication about therapies.
Who this helps: Patients with PTSD.
Peripheral blood mononuclear cell transcriptomic trajectories reveal dynamic regulation of inflammatory actors in delirium.
2025
medRxiv : the preprint server for health sciences
LaHue SC, Takegami N, Simmasalam R, Baqai A, Munoz E +19 more
Plain English This research studied how the immune system's response changes in patients with delirium, particularly those hospitalized with COVID-19. The study found that while some immune responses were initially high, they became abnormal over time, with specific genes linked to inflammation remaining active, indicating ongoing issues. Understanding these patterns is important because it can help identify ways to treat delirium effectively and improve care for patients facing this serious condition.
Who this helps: This helps patients with delirium and their healthcare providers.
A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration.
2025
Cell reports
D'Ignazio L, Lorenzetti APR, Penney EB, Evans TA, Qamar B +21 more
Plain English This study looked at a specific genetic element called SINE-VNTR-Alu (SVA) and its effect on a brain disorder known as X-linked dystonia parkinsonism (XDP). Researchers found that longer repeat sequences within the SVA are linked to earlier onset of the disease, and when they removed this genetic element in laboratory models, the signs of nerve cell damage improved significantly. This is important because it suggests a new target for treatments that could potentially slow down or prevent neurodegeneration.
Who this helps: This helps patients with XDP and researchers looking for new treatment options.
CanerClarity App: Enhancing Cancer Data Visualization with AI-Generated Narratives.
2025
Preventive oncology & epidemiology
Munoz E, VanHelene AD, Yang NT, Ramirez AG
Plain English The study focused on developing the CancerClarity app to help community cancer centers better access and share cancer data. It provides easy-to-understand narratives about cancer statistics, making complex information simpler for patients and community members. This app allows users to explore data on cancer incidence and mortality across U.S. counties, improving communication and public health decisions.
Who this helps: This benefits patients, doctors, and community health professionals.
Uncovering multilevel drivers of cancer disparities among Latinos in the United States.
2025
Frontiers in public health
Ramirez AG, Munoz E, Rodriguez-Rodriguez L, Bernal-Mizrachi L, Lopez JA +7 more
Plain English This research focused on understanding why Latinos in the United States face higher rates of certain cancers and worse outcomes than other groups. The study identified several key factors contributing to this issue, including environmental dangers, genetic risks, cultural challenges, and systemic problems like discrimination and lack of healthcare access. To effectively tackle these disparities, a multi-layered approach is needed, including research tailored to Latino communities, better access to healthcare, and changes in policies.
Who this helps: This helps Latino patients and their families, healthcare providers, and policy makers working to improve cancer care and outcomes.
Delirium in hospitalized COVID-19 patients is associated with dynamic changes in peripheral immune gene expression.
2025
GeroScience
LaHue SC, Takegami N, Simmasalam R, Baqai A, Munoz E +18 more
Plain English This study looked at how changes in the immune system affect delirium in older adults hospitalized with COVID-19. Researchers analyzed blood samples from 64 patients and found that those with delirium had persistent changes in genes related to the immune response, especially those involved in inflammation. Specifically, certain immune genes increased over time in these patients, while others decreased, which can worsen delirium. Understanding these changes can help develop better treatments to prevent or manage delirium, especially in older patients.
Who this helps: Older patients in hospitals, their families, and healthcare providers.
Correction: Uncovering multilevel drivers of cancer disparities among Latinos in the United States.
2025
Frontiers in public health
Ramirez AG, Munoz E, Rodriguez-Rodriguez L, Bernal-Mizrachi L, Chalela P +8 more
Plain English The researchers looked into the different factors that cause cancer disparities among Latinos in the United States. They found that social, economic, and healthcare-related issues all play a big role in why Latinos experience higher rates of certain cancers. Understanding these factors is important because it can lead to better support and treatments tailored for these communities.
Who this helps: This helps Latino patients and the healthcare system in addressing cancer care more effectively.
Amelie G Ramirez Lorna Rodriguez-Rodriguez Leon Bernal-Mizrachi Jose Aron Lopez Paulo S Pinheiro Barbara Segarra-Vasquez Gregory Talavera Luis G Carvajal-Carmona Adolfo Diaz Duque Cliff Despres
Physician data sourced from the
NPPES NPI Registry
.
Publication data from
PubMed
.
Plain-English summaries generated by AI.
Not medical advice.