PrognosisWounds and InjuriesSurgical Procedures, OperativeMental HealthLogistic ModelsSeverity of Illness IndexLength of StayClopidogrelHospital MortalitySocial SupportPlatelet TransfusionAlopeciaIntensive Care UnitsPredictive Value of TestsIntracranial Hemorrhage, Traumatic
Dr. Muakkassa studies how various factors, particularly childhood experiences and traumatic events, affect adult health and recovery. For instance, he highlights the importance of emotional support during childhood in helping individuals cope with trauma in adulthood. Additionally, he examines practical medical questions, such as the appropriateness of platelet transfusions in patients with brain injuries who are taking blood-thinning medications. His research also delves into modern treatments for hair loss and the implications of infections in intensive care settings, ensuring that patients receive the most effective care based on their specific conditions.
Key findings
Emotional support during childhood leads to better social connections in adulthood, helping individuals adjust after trauma, while negative experiences worsen psychological issues over time.
In a study of 224 patients with traumatic brain bleeding, those receiving platelet transfusions had worse outcomes, with longer ICU stays and a higher risk of death.
Patients admitted due to trauma had a 100% survival rate from Clostridium difficile infections, compared to an 81% rate for medical patients, highlighting the differences in risk factors.
Low-level laser therapy devices for hair loss received 47 FDA approvals, indicating a growing trend in treatment options for androgenetic alopecia.
Among 498 cancer patients, survival rates were significantly lower (56%) for those who experienced physical trauma before their cancer diagnosis compared to those whose trauma occurred afterward (80%).
Frequently asked questions
Does Dr. Muakkassa study the effects of childhood experiences on mental health?
Yes, his research emphasizes how emotional support during childhood can improve coping mechanisms in adulthood after trauma.
What treatments has Dr. Muakkassa researched for hair loss?
He has studied low-level laser therapy devices that are approved for treating androgenetic alopecia, showing a growing number of options for patients.
Is Dr. Muakkassa's work relevant to patients with traumatic brain injuries?
Yes, his studies specifically address the effectiveness of treatments like platelet transfusions in patients with traumatic brain injuries, informing their care.
How does Dr. Muakkassa's research help ICU patients?
His work on Clostridium difficile infections and outcomes in ICU patients helps doctors better manage and identify risks for critically ill patients.
What is the impact of physical trauma on cancer survival according to Dr. Muakkassa's research?
His study found that patients with physical trauma before their cancer diagnosis had significantly lower survival rates compared to those who experienced trauma afterward.
Publications in plain English
Can the positive buffer the negative? Testing the impact of protective childhood experiences on adjustment in adults following trauma exposure.
2024
Anxiety, stress, and coping
Nguyen TNM, Disabato DJ, Gunstad J, Delahanty DL, George R +3 more
Plain English This study looked at how positive experiences during childhood, like having emotional support, affect how adults cope after experiencing trauma. Researchers found that while overall protective childhood experiences didn’t directly reduce psychological issues, having emotional support in childhood did lead to better social connections, which helped with adjusting after traumatic events. In contrast, negative childhood experiences made psychological issues worse over time.
Who this helps: This research benefits patients who have experienced trauma and their healthcare providers by highlighting the importance of emotional support during childhood.
Cardiac Oscillations Complicating Brain Death Diagnosis.
2023
Case reports in critical care
Bolt B, Muakkassa F, Bruening L, Marcus C, Cunningham B +3 more
Plain English This study looked at a 27-year-old man who suffered a cardiac arrest after being exposed to toxic gases and was later diagnosed with brain death. During his examination, doctors noted unusual heart activity known as cardiac oscillations, which made it challenging to determine his true condition. Clarifying these oscillations is crucial because they can lead to confusion in diagnosing brain death, ensuring patients are accurately assessed.
Who this helps: This helps doctors making critical decisions about brain death diagnoses.
Routine platelet transfusion in patients with traumatic intracranial hemorrhage taking antiplatelet medication: Is it warranted?
2022
Canadian journal of surgery. Journal canadien de chirurgie
Wolff C, Muakkassa F, Marley R, El-Khatib A, Docherty C +3 more
Plain English This study looked at whether giving platelet transfusions to patients with traumatic brain bleeding who were on blood-thinning medications like aspirin or clopidogrel is helpful. Researchers found that out of 224 patients, those who received platelet transfusions did not have better outcomes and may have faced worse situations, such as longer stays in the ICU and a higher risk of in-hospital death. This is important because it suggests that platelet transfusions in these cases may not be necessary and could lead to worse results for patients.
Who this helps: Patients with traumatic brain injuries and their doctors.
Shedding light on the FDA's 510(k) approvals process: low-level laser therapy devices used in the treatment of androgenetic alopecia.
2019
The Journal of dermatological treatment
Wang S, Seth D, Ezaldein H, Tripathi R, Merati M +2 more
Plain English This study looked at low-level laser therapy devices that treat hair loss, specifically androgenetic alopecia, by reviewing FDA approval records from 2000 to mid-2018. They found that 47 of these devices were approved, with more being introduced since 2007, indicating a growing trend in available treatments for both men and women. It's important because while there are many options now, some may not be clearly explained, which could confuse consumers.
Who this helps: This helps patients experiencing hair loss.
Clostridium difficile Infection in Trauma, Surgery, and Medical Patients Admitted to the Intensive Care Unit.
2018
Surgical infections
Watkins RR, Mangira C, Muakkassa F, Donskey CJ, Haller NA
Plain English This study looked at how Clostridium difficile infections (CDI) affect patients in intensive care units (ICUs) differently based on their type of admission—trauma, surgery, or medical reasons. Researchers found that trauma and surgery patients had longer ICU stays, more days on ventilators and catheters, and a better survival rate (100% vs. 81%) compared to medical patients. These results highlight that factors like longer ICU stays and specific antibiotic use may increase the risk of CDI, especially for trauma and surgery patients.
Who this helps: This information benefits doctors treating ICU patients by helping them better identify and manage the risk of CDI.
Feasibility of carotid artery PET/MRI in psoriasis patients.
2016
American journal of nuclear medicine and molecular imaging
Rajiah P, Hojjati M, Lu Z, Kosaraju V, Partovi S +9 more
Plain English This study looked at how well a special imaging technique called PET/MRI works for examining the carotid arteries in patients with psoriasis. Researchers tested eleven psoriasis patients and ten healthy individuals, measuring specific values related to arterial wall health. They found that while the imaging was successful, no significant plaque was identified in any of the patients, which is important because it shows that PET/MRI can be a useful tool for monitoring cardiovascular health in this group.
Who this helps: This helps patients with psoriasis by providing doctors with better ways to assess their heart health.
A comparison between survival from cancer before and after a physical traumatic injury: physical trauma before cancer is associated with decreased survival.
2015
Journal of trauma management & outcomes
Delahanty DL, Marley R, Fenton A, Salvator A, Woofter C +3 more
Plain English This study looked at how surviving a physical injury before being diagnosed with cancer affects overall survival rates in patients. Among the 498 patients analyzed, those who had a physical trauma before their cancer diagnosis had a survival rate of just 56%, compared to 80% for those who experienced trauma after their cancer diagnosis. This matters because it indicates that having a history of physical injury may significantly increase the risk of dying from cancer.
Who this helps: This information helps doctors in better understanding patient histories and potentially improving care for cancer patients with prior injuries.
Prospective study of the clinical predictors of a positive abdominal computed tomography in blunt trauma patients.
2004
The Journal of trauma
Beck D, Marley R, Salvator A, Muakkassa F
Plain English This study examined the factors that might indicate whether a CT scan would show serious injuries in patients with blunt trauma, analyzing data from 213 patients. It found that having an abnormal pelvic X-ray significantly raised the chances of a positive CT scan (6.6 times more likely), and being intubated also increased this risk (2.6 times more likely). These findings are important because they can help doctors make better decisions about who needs a CT scan, potentially speeding up treatment for those who are more likely to have serious injuries.
Who this helps: This helps doctors and trauma care teams prioritize CT scans for patients who might need them the most.
The economic effect of child abuse in the burn unit.
1998
Burns : journal of the International Society for Burn Injuries
Evasovich M, Klein R, Muakkassa F, Weekley R
Plain English This study looked at the financial impact of child abuse related to burn injuries at a hospital over five years, involving 104 children who were potentially abused. The total healthcare cost for treating these children was about $1.2 million, with 71% coming from single-parent homes. Understanding these costs highlights the need for better prevention and awareness of child abuse, as there are significant long-term effects beyond just the immediate healthcare expenses.
Who this helps: This benefits patients, social services, and policymakers working to prevent child abuse.
Comparison of APACHE II, Trauma Score, and Injury Severity Score as predictors of outcome in critically injured trauma patients.
1993
American journal of surgery
Rutledge R, Fakhry S, Rutherford E, Muakkassa F, Meyer A
Plain English Researchers compared three scoring systems (APACHE II, Trauma Score, and Injury Severity Score) to see which best predicts outcomes for critically injured trauma patients. They looked at data from 428 patients and found that 14% died, with the APACHE II score being the most accurate predictor of survival in the ICU and the hospital. This study highlights the importance of using these scoring methods alongside clinical assessments to better evaluate patient severity and risk of death.
Who this helps: This helps doctors in making more informed decisions for critically injured patients.
Prospective comparison of clinical judgment and APACHE II score in predicting the outcome in critically ill surgical patients.
1992
The Journal of trauma
Meyer AA, Messick WJ, Young P, Baker CC, Fakhry S +4 more
Plain English This study looked at how well doctors' clinical judgments compared to a scoring system called the APACHE II in predicting whether critically ill surgical patients would survive. Out of 578 patients, 40 died, making the survival prediction accuracy for doctors 95.2%, compared to 90.9% for the APACHE II score. The findings highlight that while clinical judgment is slightly better, neither method is very reliable since over 40% of those predicted to die by both methods actually survived.
Who this helps: This benefits doctors who assess critically ill patients, helping them make more informed decisions.
Acute Physiology and Chronic Health Evaluation (APACHE II) score and outcome in the surgical intensive care unit: an analysis of multiple intervention and outcome variables in 1,238 patients.
1991
Critical care medicine
Rutledge R, Fakhry SM, Rutherford EJ, Muakkassa F, Baker CC +2 more
Plain English This study looked at how well the APACHE II score, a system used to gauge the severity of illness, predicts outcomes for patients in surgical intensive care units (ICUs). Researchers analyzed data from 1,238 patients and found that while the APACHE II score was linked to various treatment measures and outcomes, its ability to accurately predict individual patient results was limited, with correlation values being quite low (from 0.03 to 0.22). This matters because it highlights that while the score can be useful for examining trends in large patient groups, it should not be relied upon for making decisions about individual patients' care.
Who this helps: This helps doctors make better-informed decisions regarding patient care in surgical ICUs.