DR. FREDERICK E. BENEDICT, MD

RALEIGH, NC

Research Active
Orthopaedic Surgery NPI registered 21+ years 15 publications 1966 – 2023 NPI: 1427052240
CatsAnticonvulsantsElectroencephalographyHippocampusTubocurarineBenzodiazepinesNeuroprotective AgentsStrychnineAntipsychotic AgentsCarbacholIsoflurophatePicrotoxinScopolamineAnterior Temporal LobectomyFructose

Practice Location

3801 WAKE FOREST RD STE 220
RALEIGH, NC 27609-6864

Phone: (919) 872-5296

What does FREDERICK BENEDICT research?

Dr. Benedict studies how to enhance the performance and reduce environmental impact of both medical treatments and machinery. He conducts research on renewable fuels to replace traditional fuels like gasoline and diesel, aiming to improve energy efficiency and lower emissions. In addition, he explores the use of advanced materials, such as graphene and cellulose, in coolants that can significantly enhance heat transfer efficiency in car radiators and other systems. Furthermore, he investigates the effects of antiepileptic medications on mental health, especially in patients undergoing surgeries for epilepsy, highlighting the importance of understanding these side effects in clinical settings.

Key findings

  • Using response surface methodology, Dr. Benedict's research has shown that optimizing renewable fuel blends can lead to lower emissions and better engine performance.
  • In another study, a hybrid coolant made with graphene nanoplatelets and cellulose nanocrystals increased heat transfer efficiency by nearly 52% compared to traditional coolants.
  • The optimal coolant mixture of aluminum oxide and nanocellulose in one study achieved maximum heat transfer properties at a concentration of 0.9%.
  • In a study on epilepsy surgery, patients who experienced medication-induced psychosis were noted to have a higher risk of developing further mental health issues post-surgery, emphasizing the need for careful patient evaluation.
  • Dr. Benedict's study on anterior spine fusion reported an average curve correction of 63% in adult scoliosis patients, although it noted complications in some cases.

Frequently asked questions

Does Dr. Benedict study epilepsy?
Yes, Dr. Benedict researches the effects of antiepileptic medications on mental health, especially in patients undergoing surgery for epilepsy.
What treatments has Dr. Benedict researched?
He has researched various treatments including surgical options for scoliosis and the implications of medications for epilepsy.
Is Dr. Benedict's work relevant to car manufacturers?
Yes, his research on renewable fuels and advanced coolants directly benefits car manufacturers looking to improve vehicle performance and reduce emissions.
What advancements in cooling systems has Dr. Benedict made?
Dr. Benedict has focused on hybrid coolants made with innovative materials that significantly enhance heat transfer, improving efficiency in automobile radiators.
Who would benefit from Dr. Benedict's research on ovarian tumors?
His research on sclerosing stromal tumors can help young women who may be misdiagnosed with more serious conditions, guiding them towards appropriate treatment.

Publications in plain English

Heat Transfer Enhancement by Hybrid Nano Additives-Graphene Nanoplatelets/Cellulose Nanocrystal for the Automobile Cooling System (Radiator).

2023

Nanomaterials (Basel, Switzerland)

Yaw CT, Koh SP, Sandhya M, Kadirgama K, Tiong SK +5 more

Plain English
This study looked at a new type of coolant made from a blend of graphene nanoplatelets and cellulose nanocrystals designed to improve heat transfer in car radiators. The researchers found that this hybrid coolant increased the efficiency of heat transfer by nearly 52% and overall heat transfer by about 47%, compared to regular water-based coolants. This breakthrough could lead to smaller, lighter radiators that cool engines better, ultimately improving vehicle performance and efficiency. Who this helps: This helps car manufacturers and drivers looking for better engine performance and efficiency.

PubMed

An Approach for the Optimization of Thermal Conductivity and Viscosity of Hybrid (Graphene Nanoplatelets, GNPs: Cellulose Nanocrystal, CNC) Nanofluids Using Response Surface Methodology (RSM).

2023

Nanomaterials (Basel, Switzerland)

Yaw CT, Koh SP, Sandhya M, Ramasamy D, Kadirgama K +5 more

Plain English
This study focused on improving the heat transfer and flow properties of special fluids made with tiny graphene particles combined with cellulose. Researchers found that by adjusting temperature and concentration, they could significantly enhance these fluids, achieving a maximum thermal conductivity of 0.4962 W/m-K and a viscosity of 2.6191 cP. This research is important because better thermal fluids can lead to more efficient cooling systems in various applications, potentially improving energy use and performance. Who this helps: This helps engineers and manufacturers who design cooling systems for electronics and other machinery.

PubMed

Advancing renewable fuel integration: A comprehensive response surface methodology approach for internal combustion engine performance and emissions optimization.

2023

Heliyon

Siaw Paw JK, Kiong TS, Kamarulzaman MK, Adam A, Hisham S +7 more

Plain English
This study examined how alternative renewable fuels can replace traditional diesel and gasoline in internal combustion engines to improve performance and reduce harmful emissions. Researchers used a method called response surface methodology (RSM) to evaluate the effectiveness of various renewable fuels. They found that using RSM can provide better insights into how these fuels perform and affect emissions, which is important for meeting environmental regulations and improving engine efficiency. Who this helps: This benefits car manufacturers and environmental regulators looking to reduce pollution and improve fuel efficiency.

PubMed

Thermal Performance of Hybrid-Inspired Coolant for Radiator Application.

2020

Nanomaterials (Basel, Switzerland)

Benedict F, Kumar A, Kadirgama K, Mohammed HA, Ramasamy D +2 more

Plain English
This study looked at how different coolant mixtures, specifically those including nanocellulose and metal oxides, perform in heat transfer applications like radiators. Researchers found that a coolant made from a mix of aluminum oxide and nanocellulose had the best heat transfer properties, especially at a concentration of 0.9%. This is important because better cooling can lead to more efficient vehicle engines and industrial equipment, potentially saving energy and improving performance. Who this helps: This benefits engineers and manufacturers in the automotive and industrial sectors.

PubMed

Antiepileptic-induced Psychosis as a Possible Predictor of Post-temporal Lobectomy Alternative Psychosis.

2016

East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan

Benedict F, Lim KS, Jambunathan ST, Hashim AH

Plain English
This study looked at a patient who experienced psychosis from the medication topiramate and then developed another type of psychosis after having surgery to remove part of the brain for epilepsy treatment. The researchers noted that as more people are considered for this type of surgery, the number of patients with mental health issues is also rising. Understanding how medication-induced psychosis might predict further mental health problems is important for planning safer surgeries. Who this helps: This helps doctors and patients considering surgery for epilepsy.

PubMed

Sclerosing stromal tumour of the ovary. A case report.

1997

Indian journal of cancer

Benedict F, Jose R, Seshadri L

Plain English
This study looked at a rare type of ovarian tumor called a sclerosing stromal tumor (SST), which appears solid and has lots of blood vessels, making it seem like it might be cancerous. Even though these tumors occur mostly in young women, they are actually benign, meaning they are not cancer. The findings emphasize the need for careful evaluation before proceeding with major surgery since the SST can be mistaken for a more serious condition. Who this helps: This helps young women who might be diagnosed with ovarian tumors.

PubMed

Anterior spine fusion using Zielke instrumentation for adult thoracolumbar and lumbar scoliosis.

1991

Spine

Trammell TR, Benedict F, Reed D

Plain English
This study looked at how effective a specific type of spine surgery, called anterior spine fusion, was for adult patients with scoliosis, focusing on results from surgeries done between 1983 and 1986. The surgery resulted in an average curve correction of 63%, improved spine alignment by 8 degrees, and significantly reduced vertebral rotation by 37%. However, there were complications, including hardware failures in eight patients and one case of deep infection, particularly among older patients and those with more severe spine curves. Who this helps: This benefits adults with thoracolumbar and lumbar scoliosis who are considering surgery for pain and curve progression.

PubMed

Dynamic posterior shift test. An adjuvant in evaluation of posterior tibial subluxation.

1989

The American journal of sports medicine

Shelbourne KD, Benedict F, McCarroll JR, Rettig AC

Plain English
The study focused on a new test called the dynamic posterior shift test, which helps doctors evaluate certain knee injuries, specifically those related to instability at the back of the knee. The test was found to be reliable and more effective than other methods; it can accurately reproduce feelings of instability in patients by causing a noticeable "clunk" when their knee is nearly straightened. This matters because it gives doctors a better way to assess and diagnose knee issues, improving treatment strategies for their patients. Who this helps: This helps both patients with knee instability and doctors diagnosing these conditions.

PubMed

[Being a nurse in a vocational education high school].

1982

Soins; la revue de reference infirmiere

Benedict F

PubMed

Albumin Mexico (Al Me ) in the Guatemalan highlands.

1973

American journal of physical anthropology

Johnston FE, Alarcon O, Benedict F, Dary M, Galbraith M +1 more

PubMed

Influence of increased local cholinergic activity on discharge patterns of hippocampal foci.

1970

Electroencephalography and clinical neurophysiology

Baker WW, Benedict F

PubMed

Analysis of local discharges induced by intrahippocampal microinjection of carbachol or diisopropylfluorophosphate (DFP).

1968

International journal of neuropharmacology

Baker WW, Benedict F

PubMed

Differential responses of hippocampal repetitive discharges to scopolamine and pentobarbital.

1968

Experimental neurology

Baker WW, Benedict F

PubMed

Local electrographic responses to intrahippocampal d-tubocurarine and related neuromuscular blocking agents.

1967

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

Baker WW, Benedict F

PubMed

Effects of ethanol on chemically-induced hippocampal foci.

1966

Archives internationales de pharmacodynamie et de therapie

Baker WW, Benedict F

PubMed

Frequent Co-Authors

W W Baker K Kadirgama D Ramasamy Chong Tak Yaw Sieh Kiong Tiong M Samykano Johnny Koh Siaw Paw Tiong Sieh Kiong Mohd Kamal Kamarulzaman Abdullah Adam

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.