Massive tissue necrosis after hydroxyzine injection.
1995The Journal of the American Osteopathic Association
Tokodi G, Huber FC
Plain English
In this study, doctors looked at a 47-year-old man who developed severe tissue damage after receiving an injection of hydroxyzine, a medication often used for anxiety and allergies. Four weeks later, after experiencing increasing pain, the patient had to undergo surgery to remove 100 grams of dead tissue from his buttock, resulting in muscle loss and a permanent limp. The problem occurred because the injection accidentally hit a nearby artery, causing serious complications, leading researchers to advise against using hydroxyzine injections into muscles.
Who this helps: This information benefits doctors and patients by highlighting the risks associated with hydroxyzine injections.