Dr. Mitri studies how specific factors like vitamin levels, technological training methods, and treatment combinations can improve health outcomes for patients with conditions such as fibromyalgia, chronic graft-versus-host disease, and various cancers. He uses both traditional clinical methods and innovative technologies, such as virtual reality, to enhance patient care, particularly for older adults and those at risk of severe health implications from diseases like COVID-19 and cancer.
Key findings
In a study on virtual reality training, older participants received physical feedback and had 0.63 collisions with obstacles compared to 0.75 without feedback.
In his research on fibromyalgia, it was found that 42.4% of 2,142 patients had low vitamin B12 levels, correlating with a 39% higher chance of reporting fatigue.
After COVID-19, 34.9% of surveyed patients reported lingering symptoms, with 75.9% experiencing fatigue and 60.3% suffering sleep issues.
Using extracorporeal photopheresis in chronic graft-versus-host disease patients showed a response rate of 74.1% compared to 60.9% for standard treatment alone.
Increasing use of febuxostat for managing gout led to a 6.3% increase in patients achieving target uric acid levels while decreasing gout flare-ups by 1.4%.
Frequently asked questions
Does Dr. Mitri study the treatment of fibromyalgia?
Yes, he researches the link between vitamin levels and symptoms like fatigue in fibromyalgia patients.
What is extracorporeal photopheresis and how is it used in treatment?
It's a therapy that involves treating blood outside the body with light and is used for conditions like chronic graft-versus-host disease.
Are Dr. Mitri's findings relevant for older adults at risk of falling?
Absolutely, his research on virtual reality training aims to help older adults avoid obstacles and reduce fall risks.
How does Dr. Mitri's work help patients recovering from COVID-19?
His studies address the ongoing effects after COVID-19, identifying which patients may need additional support for long-term symptoms.
What impact does Dr. Mitri's research have on gout patients?
His findings highlight cost-effective treatment options and improved management strategies for gout, particularly in patients with chronic kidney disease.
Publications in plain English
Virtual obstacle-avoidance training using daily-life obstacles with physical feedback in older people: A cross-over trial.
2025
Archives of gerontology and geriatrics
He Y, Lee J, Kim J, Brodie MA, Mitri G +4 more
Plain English This study tested a virtual reality (VR) training program designed to help older adults avoid obstacles while walking. Researchers found that when participants received physical feedback during the training, they had fewer collisions with obstacles—0.63 collisions with feedback compared to 0.75 without it. This training is important because it can lead to fewer falls, which can severely impact the health and independence of older people.
Who this helps: Older adults at risk of falling.
Determination of asbestos cement rooftop surface composition using regression analysis and hyper-spectral reflectance data in the visible and near-infrared ranges.
2024
Journal of hazardous materials
Sabat M, Fares N, Mitri G, Kfoury A
Plain English This study examined the materials used in asbestos-cement rooftops by analyzing their surface composition without taking samples directly. Researchers found varying amounts of weathered cement, dangerous asbestos fibers (specifically types called chrysotile and cummingtonite), and plant growth like lichens, using advanced imaging techniques combined with statistical methods. This is important because it provides a safer way to identify hazardous materials in building rooftops, which can help protect public health.
Who this helps: Patients, especially those living in urban areas with asbestos-related risks.
Perception, Prevalence, and Prediction of Severe Infection and Post-acute Sequelae of COVID-19.
2022
The American journal of the medical sciences
Knight DRT, Munipalli B, Logvinov II, Halkar MG, Mitri G +2 more
Plain English This study looked at how many people experienced long-term effects after having COVID-19, focusing on their symptoms and what factors made these effects more likely. Out of 437 patients surveyed, 34.9% reported ongoing symptoms like fatigue (75.9%) and sleep issues (60.3%) more than three months after infection, regardless of whether they had been hospitalized. Understanding these lasting effects helps identify which patients may need additional support and treatment to recover fully.
Who this helps: This helps patients recovering from COVID-19, especially those with long-lasting symptoms.
Association of Vitamin B12, Vitamin D, and Thyroid-Stimulating Hormone With Fatigue and Neurologic Symptoms in Patients With Fibromyalgia.
2022
Mayo Clinic proceedings. Innovations, quality & outcomes
Munipalli B, Strothers S, Rivera F, Malavet P, Mitri G +2 more
Plain English This study looked at the link between vitamin B12 levels and symptoms like fatigue and memory loss in people with fibromyalgia. Out of 2,142 patients, 42.4% had low vitamin B12 levels, and those patients were more likely to report fatigue. The findings indicate that those with B12 deficiency had 39% higher chances of experiencing fatigue, showing that addressing vitamin B12 deficiency could be crucial for improving quality of life in these patients.
Who this helps: Patients with fibromyalgia suffering from fatigue and related symptoms.
Real-world use of extracorporeal photopheresis for patients with cutaneous T-cell lymphoma in the United States: 2010-2015.
2020
The Journal of dermatological treatment
Ling YL, Huang X, Mitri G, Lovelace B, Pham A +3 more
Plain English Researchers studied how extracorporeal photopheresis (ECP) was used to treat patients with cutaneous T-cell lymphoma (CTCL) in the U.S. between 2010 and 2015. They found that about 10.6% of patients receiving systemic therapy used ECP, which was linked to shorter hospital stays (6.67 days for ECP patients compared to 11.80 days for those not using ECP). This matters because ECP may be a valuable option for patients with CTCL, helping them spend less time in the hospital.
Who this helps: This helps patients with cutaneous T-cell lymphoma.
Derivatization and combination therapy of current COVID-19 therapeutic agents: a review of mechanistic pathways, adverse effects, and binding sites.
2020
Drug discovery today
El Kantar S, Nehmeh B, Saad P, Mitri G, Estephan C +3 more
Plain English This study examined how existing COVID-19 treatments can be improved by combining them with other drugs and modifying their structures to enhance their effectiveness. It found that using different drugs that work in various ways could lead to better treatment outcomes for patients. For example, focusing on how drugs bind to the virus's protein spikes can help researchers develop safer and more effective therapies.
Who this helps: This benefits patients battling COVID-19 by improving treatment options.
Risk assessment of asbestos-cement roof sheets in Chekka, North Lebanon.
2019
Environmental monitoring and assessment
Kfoury A, Mitri G, Arab D, El Zakhem H, Aouad G
Plain English This study looked at the safety of asbestos-cement rooftops in Chekka, North Lebanon, where these materials have been used since the 1950s. Researchers found that while many rooftops appeared to be in good condition, they were actually at a high risk of releasing dangerous asbestos fibers, especially in areas where people frequently interact with them. The presence of harmful fibers was confirmed through testing, highlighting significant risks to the local community.
Who this helps: This research benefits local residents and health officials in Chekka who need to address asbestos exposure risks.
Randomized controlled study of ECP with methoxsalen as first-line treatment of patients with moderate to severe cGVHD.
2019
Blood advances
Jagasia M, Scheid C, Socié G, Ayuk FA, Tischer J +8 more
Plain English This research studied the effectiveness of a treatment called extracorporeal photopheresis (ECP) combined with standard medications for patients with moderate to severe chronic graft-versus-host disease (cGVHD), a condition that can occur after a stem cell transplant. In a group of 53 patients, those receiving ECP along with standard care had a response rate of 74.1% after 28 weeks, compared to 60.9% for those receiving standard care alone. This is significant because it shows that adding ECP may improve treatment outcomes and maintain quality of life without a decline seen in the standard care group.
Who this helps: This benefits patients with moderate to severe cGVHD.
Assessing land degradation and identifying potential sustainable land management practices at the subnational level in Lebanon.
2019
Environmental monitoring and assessment
Mitri G, Nasrallah G, Gebrael K, Bou Nassar M, Abou Dagher M +3 more
Plain English This study looked at land degradation in Lebanon to help decision-makers manage the land effectively. Researchers used maps and on-the-ground data to track changes in vegetation, land productivity, and soil health. They found that understanding these changes is crucial for developing sustainable practices and preventing further damage, which can help achieve land degradation neutrality as part of a global sustainability goal.
Who this helps: This research benefits local farmers, environmental planners, and community leaders in Lebanon.
The role of screening MRI in the era of next generation sequencing and moderate-risk genetic mutations.
2018
Familial cancer
Macklin S, Gass J, Mitri G, Atwal PS, Hines S
Plain English This study looked at the importance of using breast MRI screenings for women who have certain genetic mutations that increase their risk of breast cancer. It found that combining breast MRI with mammograms detects 94% of breast cancers, making it a more effective screening method. The findings are particularly important for women with a lifetime breast cancer risk of 20% or more, as they should receive both screenings to better manage their health.
Who this helps: This helps women with moderate to high genetic risk for breast cancer.
Determining the Accuracy and Reliability of Indirect Calorimeters Utilizing the Methanol Combustion Technique.
2018
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
Kaviani S, Schoeller DA, Ravussin E, Melanson EL, Henes ST +9 more
Plain English This study compared different machines that measure how our bodies use energy, using a special technique involving burning methanol. Out of 12 devices tested, three machines (Omnical, Cosmed Quark, and Parvo) were found to be very accurate, measuring energy use within 2% of the true values, while eight machines showed reliable performance. This research matters because it helps identify which devices provide the best data for assessing metabolism, ensuring patients receive accurate evaluations.
Who this helps: Patients and healthcare providers who rely on metabolic testing for health assessments.
Radar evidence of subglacial liquid water on Mars.
2018
Science (New York, N.Y.)
Orosei R, Lauro SE, Pettinelli E, Cicchetti A, Coradini M +17 more
Plain English Scientists studied the area under the ice at the south pole of Mars using radar and found clear signs of liquid water trapped there. They detected a bright zone about 20 kilometers wide that likely contains this water, with measurements showing it has properties similar to water. This discovery is important because it could have implications for understanding past life on Mars and future exploration.
Who this helps: This helps researchers studying Mars and the search for extraterrestrial life.
Febuxostat in the management of gout: a cost-effectiveness analysis.
2016
Journal of medical economics
Smolen LJ, Gahn JC, Mitri G, Shiozawa A
Plain English This study looked at the cost-effectiveness of two gout medications: febuxostat and allopurinol. Over five years, it found that using febuxostat could save money while also helping patients avoid flares and progression of kidney disease, with costs of about $5,377 to help a patient reach their target uric acid level and $1773 for each flare avoided. This is important because it shows that febuxostat is a better choice for managing gout, especially for patients with chronic kidney disease.
Who this helps: Gout patients, particularly those with chronic kidney disease.
Cost Comparison of Urate-Lowering Therapies in Patients with Gout and Moderate-to-Severe Chronic Kidney Disease.
2016
Journal of managed care & specialty pharmacy
Mitri G, Wittbrodt ET, Turpin RS, Tidwell BA, Schulman KL
Plain English This study looked at how much it costs to treat gout in patients with moderate-to-severe chronic kidney disease (CKD) using two medications: allopurinol and febuxostat. It found that patients starting on febuxostat had lower overall costs ($1,299) compared to those starting on allopurinol ($1,487) when using febuxostat as a first-line treatment. However, if they switched to febuxostat after using allopurinol, their costs went up significantly ($1,751). This information is important because it can help doctors choose the most cost-effective treatment for gout patients who also have CKD.
Who this helps: This benefits patients with gout and chronic kidney disease, as well as their doctors.
The Budget Impact of Increased Use of Febuxostat in the Management of Gout: A US Health Plan Managed Care Pharmacy and Medical Costs Perspective.
2016
Clinical therapeutics
Smolen LJ, Gahn JC, Mitri G, Shiozawa A
Plain English This study looked at how using more of the drug febuxostat for treating gout could impact healthcare costs over three years. As more patients switched to febuxostat, the study found that 6.3% more patients met the target uric acid levels and gout flare-ups decreased by 1.4%. While the total treatment costs rose by 1.4%, savings from reduced gout-related medical expenses, especially for kidney disease, largely balanced out these costs over time.
Who this helps: This benefits gout patients and their doctors by providing better treatment options and potential long-term savings.
Evaluating exposure to land degradation in association with repetitive armed conflicts in North Lebanon using multi-temporal satellite data.
2014
Environmental monitoring and assessment
Mitri G, Nader M, Van der Molen I, Lovett J
Plain English This study looked at how repeated armed conflicts in North Lebanon affect land quality using satellite images. The researchers created maps showing land changes and found that 90% of their assessments accurately reflected the impact of these conflicts on land degradation. Understanding this connection is crucial for planning recovery efforts and making informed policies that help restore the environment after such conflicts.
Who this helps: This benefits policymakers, environmental planners, and communities affected by conflict.
Work hour regulations: do we need further changes now? A survey of internal medicine faculty and residents.
2009
Journal of graduate medical education
Sloan S, Krishnamurthy M, Lyon DT, Mitri G, Chyshkevych I +1 more
Plain English The study surveyed internal medicine faculty and residents about work hour regulations for medical training, especially following recommendations for shorter hours to improve safety. The results showed that most faculty opposed these proposed changes, believing there is no clear proof that fewer work hours lead to better patient care or education, while first-year residents and those working extra jobs reported more stress and favored reduced hours. This matters because it highlights the differing views on how to best ensure the well-being of medical trainees and patient safety.
Who this helps: This helps medical residents and potentially improves conditions for patients.