Does Dr. Ripich study kidney health?

Yes, Dr. Ripich focuses on how harmful substances like ochratoxin A affect kidney function.

What treatments has Dr. Ripich researched?

While Dr. Ripich's work primarily investigates the effects of toxins, understanding these mechanisms can inform potential treatments for kidney damage.

Is Dr. Ripich's work relevant to patients exposed to toxins?

Yes, his research is directly relevant to patients at risk of kidney damage from mycotoxins, helping to highlight potential health risks.

What is ochratoxin A?

Ochratoxin A is a toxin produced by certain fungi, often found in contaminated food, that can harm kidney function.

How does ochratoxin A affect kidney function?

Dr. Ripich's research shows that ochratoxin A disrupts the normal transport processes in kidney cells, which is critical for filtering blood.

GREGORY GUIDO RIPICH, MD

HAMILTON, NY

Research Active

Surgery NPI registered 21+ years 1 publication 1988 – 1988 NPI: 1255336582

Surgery

Biological TransportDogsIn Vitro TechniquesTritiumNiacinamideKidney CortexMicrovilliOchratoxinsp-Aminohippuric Acid

Practice Location

150 BROAD ST
HAMILTON, NY 13346-9575

Phone: (315) 824-7040

What does GREGORY RIPICH research?

Dr. Ripich studies the effects of ochratoxin A (OTA) on kidney health. OTA is a toxin that can enter the body through contaminated food and is known to pose a risk to kidney function. In his research, he explores how OTA disrupts the normal transport of compounds in kidney cells, which is crucial for filtering waste from the blood. Understanding this process is important for protecting patients at risk of kidney damage from mycotoxins, which can lead to serious health issues.

Key findings

Ochratoxin A reduces the uptake of organic compounds by kidney membranes, requiring concentrations of about 20 micromoles for half of its effect in one type of membrane.
In another type of membrane, ochratoxin A requires concentrations of 32 micromoles to significantly affect the transport of compounds.
Understanding the transport mechanisms affected by ochratoxin A provides insights into potential risks for kidney damage in patients exposed to mycotoxins.

Frequently asked questions

Does Dr. Ripich study kidney health?: Yes, Dr. Ripich focuses on how harmful substances like ochratoxin A affect kidney function.
What treatments has Dr. Ripich researched?: While Dr. Ripich's work primarily investigates the effects of toxins, understanding these mechanisms can inform potential treatments for kidney damage.
Is Dr. Ripich's work relevant to patients exposed to toxins?: Yes, his research is directly relevant to patients at risk of kidney damage from mycotoxins, helping to highlight potential health risks.
What is ochratoxin A?: Ochratoxin A is a toxin produced by certain fungi, often found in contaminated food, that can harm kidney function.
How does ochratoxin A affect kidney function?: Dr. Ripich's research shows that ochratoxin A disrupts the normal transport processes in kidney cells, which is critical for filtering blood.

Publications in plain English

Mechanism of ochratoxin A transport in kidney.

1988

The Journal of pharmacology and experimental therapeutics

Sokol PP, Ripich G, Holohan PD, Ross CR

Plain English
This study looked at how a harmful substance called ochratoxin A (OTA), produced by a fungus, affects the transport of another compound in kidney cells. Researchers found that OTA significantly reduces the uptake of a typical organic compound by kidney membranes, requiring concentrations of about 20 micromoles for half its effect in one type of membrane, and 32 micromoles in another. Understanding how OTA interferes with kidney function is important because it highlights a potential risk for kidney damage from this toxin. Who this helps: This information benefits patients at risk of kidney damage from mycotoxins.

PubMed

Frequent Co-Authors

P P Sokol P D Holohan C R Ross

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.