Does Dr. Rowin study high blood pressure?

Yes, Dr. Rowin's research specifically focuses on finding new ways to treat high blood pressure.

What treatments has Dr. Rowin researched?

Dr. Rowin has researched the compound L-681,176, which inhibits an enzyme linked to high blood pressure.

Is Dr. Rowin's work relevant to patients with hypertension?

Absolutely, his findings could lead to new treatments that help manage hypertension effectively.

DR. GREGORY SPENCER ROWIN, DO

MCALLEN, TX

Research Active

Otolaryngology - Plastic Surgery within the Head & Neck NPI registered 21+ years 2 publications 1967 – 1984 NPI: 1821093212

Otolaryngology - Plastic Surgery within the Head & Neck

RatsBrainDuodenumAngiotensin-Converting Enzyme InhibitorsOligopeptidesBlood PressureIn Vitro TechniquesEpididymisAdrenal GlandsGuanidinesElectron Transport Complex IVStreptomycesTeprotideAcid PhosphataseGlycoside Hydrolases

Practice Location

2101 S CYNTHIA ST
MCALLEN, TX 78503-1294

Phone: (956) 687-7896

What does GREGORY ROWIN research?

Dr. Rowin studies how specific substances can affect blood pressure regulation. His most notable research centers around a compound named L-681,176, derived from a type of bacteria. This compound acts by blocking an enzyme that plays a significant role in increasing blood pressure. By exploring this and similar substances, he aims to uncover new, effective treatments for patients suffering from high blood pressure, also known as hypertension.

Key findings

L-681,176 can inhibit the angiotensin-converting enzyme with a small effective dose of just 1.3 micrograms per milliliter.
In animal studies, a dose of 142 mg per kilogram of L-681,176 led to a significant decrease in blood pressure response.
The research indicates potential for L-681,176 to contribute to new treatments for high blood pressure.

Frequently asked questions

Does Dr. Rowin study high blood pressure?: Yes, Dr. Rowin's research specifically focuses on finding new ways to treat high blood pressure.
What treatments has Dr. Rowin researched?: Dr. Rowin has researched the compound L-681,176, which inhibits an enzyme linked to high blood pressure.
Is Dr. Rowin's work relevant to patients with hypertension?: Absolutely, his findings could lead to new treatments that help manage hypertension effectively.

Publications in plain English

Discovery, purification and characterization of the angiotensin converting enzyme inhibitor, L-681,176, produced by Streptomyces sp. MA 5143a.

1984

The Journal of antibiotics

Huang L, Rowin G, Dunn J, Sykes R, Dobna R +3 more

Plain English
Researchers studied a substance called L-681,176, which can block an enzyme involved in regulating blood pressure, and found it in the bacteria Streptomyces sp. MA 5143. They discovered that it is effective in small amounts, requiring only about 1.3 micrograms per milliliter to inhibit the enzyme, and in rats, it decreased the blood pressure response significantly with a dose of 142 mg per kilogram. This discovery is important because it could lead to new treatments for high blood pressure. Who this helps: Patients with high blood pressure.

PubMed

Mammalian alpha-acetylglucosaminidase. Enzymic properties, tissue distribution, and intracellular localization.

1967

Biochemistry

Weissmann B, Rowin G, Marshall J, Friederici D

PubMed

Frequent Co-Authors

L Huang J Dunn R Sykes R Dobna B A Mayles D M Gross R W Burg B Weissmann J Marshall D Friederici

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.