Dr. Stephenson studies how health factors before conception can affect pregnancy outcomes, emphasizing the importance of both men's and women's health in planning for families. He also investigates how external factors like climate change influence health risks, particularly the increased risk of strokes. In addition to these areas, he explores treatments for conditions such as swallowing disorders and cancer, focusing on how new technologies and therapies can enhance patient care and recovery processes.
Key findings
Dr. Stephenson found that improving preconception health can lead to better pregnancy outcomes, particularly for marginalized communities, highlighting the need for equitable healthcare practices.
In stroke research, exposure to cold weather increases stroke risk, particularly among older adults and low-income populations, revealing a critical link between climate change and brain health.
A study on liquid thickeners indicated that a new product, Precise Thick•N INSTANT, was preferred over traditional thickeners, improving patient satisfaction scores by an average of 3.83 points.
His systematic review on physiotherapy treatments for stroke patients showed an average improvement of 3 points on the Trunk Impairment Scale, a crucial measurement for sitting balance.
The development of CFT1946 demonstrated strong effectiveness against BRAFV600-mutant cancers, offering hope for patients with tumors resistant to traditional therapies.
Frequently asked questions
Does Dr. Stephenson study preconception health?
Yes, he focuses on how health before conception affects pregnancy outcomes for both men and women.
What impact does climate change have on health according to Dr. Stephenson?
He found that climate change, particularly cold weather, increases the risk of strokes, especially in vulnerable population groups.
What advancements in cancer treatments has Dr. Stephenson researched?
He researched a new drug called CFT1946, which effectively targets BRAFV600-mutant tumors, offering promising results for resistant cancer cases.
How does Dr. Stephenson improve rehabilitation for patients after trauma?
He examines the use of digital health tools to enhance recovery, finding positive outcomes especially in patients with spinal cord injuries.
What are the benefits of the new liquid thickener that Dr. Stephenson studied?
The new thickener, Precise Thick•N INSTANT, was found to be more enjoyable to drink, leading to higher patient satisfaction and better hydration for those with swallowing difficulties.
Publications in plain English
Impact of International Department of Defense Surgical Missions on Readiness: Perspectives from Military Surgeons.
2026
Military medicine
Kim S, Katawal P, Mitra D, Lee R, Raiciulescu S +5 more
Plain English This study looked at how participating in international surgical missions affects military surgeons' readiness for deployment. Out of 47 military surgeons surveyed, 55% found these missions beneficial for their readiness, particularly when they managed complex cases or treated critically ill patients, while others felt neutral or unhelpful about the experience. The findings emphasize the importance of exposure to complicated cases during these missions to maintain surgical skills, which is vital for military preparedness.
Who this helps: This benefits military surgeons who are preparing for deployment and improving their surgical skills.
Visualization of Breast Cancer Using Contrast-Enhanced Optical Coherence Elastography Based on Tissue Heterogeneity.
2026
IEEE transactions on medical imaging
Li J, Foo KY, Sanderson RW, Zilkens R, Hardie M +14 more
Plain English This study examined a new method for improving the detection of breast cancer using a technique called optical coherence elastography (OCE), which looks at the mechanical properties of breast tissue. Researchers developed a new approach that achieved a remarkable accuracy of 98.6% and a sensitivity of 95% in imaging, allowing them to better identify cancerous areas in the tissue. This advancement is important because it could lead to better outcomes in breast-conserving surgeries by ensuring that all cancerous cells are removed.
Who this helps: Patients undergoing breast cancer surgery.
CFT1946 Is an Orally Available Brain-Penetrant BRAFV600-Mutant Degrader That Overcomes BRAF Inhibitor Resistance.
2026
Cancer research
Kreger BT, Liang Y, Reilly NM, Spears ME, Scott WA +23 more
Plain English Researchers developed a new drug called CFT1946 to treat cancers driven by a mutation called BRAFV600. This drug is designed to work in the brain and to avoid some common issues seen with existing treatments, such as side effects and resistance to therapy. In tests, CFT1946 showed strong effectiveness against melanoma and colorectal cancer with this mutation, offering hope for patients who have not responded to traditional BRAF inhibitors.
Who this helps: This helps patients with BRAFV600-mutant tumors, especially those whose cancers have become resistant to other treatments.
The effectiveness of physiotherapy sitting balance treatments on sitting balance outcomes in early sub-acute stroke. A systematic review and meta-analysis.
Plain English This study looked at how effective different physiotherapy treatments are for improving sitting balance in people who have had a stroke within the last three months. They found that these treatments significantly improve sitting balance, with an average improvement of about 3 points on the Trunk Impairment Scale, which measures sitting control. This is important because better sitting balance is linked to improved ability to perform daily activities, influencing recovery and independence after a stroke.
Who this helps: This benefits patients recovering from stroke and their healthcare providers.
Preconception health as a target for improved pregnancy outcomes: Where do we go from here?
2026
Pregnancy hypertension
Jancsura MK, Bernstein I, Hansson SR, Cantonwine DE, Godfrey KM +5 more
Plain English This research looked at how the health of both women and men before pregnancy affects pregnancy outcomes. It found that a person's overall health — what scientists call the "exposome" — plays a critical role in increasing the risk for issues like preeclampsia. The findings highlight the need for better research and healthcare practices to improve pregnancy results by focusing on health before conception.
Who this helps: This benefits expectant parents and healthcare providers focused on prenatal care.
Clinicians' Perspectives of the Pressure Injury Treatment Advisory 'PITA' Quick Guide: An Evaluation Across Three Australian Healthcare Settings.
2026
International wound journal
Barakat-Johnson M, Ryan H, Leahy C, Stephenson J, Lai M +9 more
Plain English This study looked at how useful a guide called the Pressure Injury Treatment Advisory (PITA) Quick Guide is for healthcare workers managing pressure injuries, which can cause serious problems like infections and longer hospital stays. Out of 302 surveyed clinicians from different healthcare settings in Australia, over 95% found the guide effective and easy to use. This is important because it shows that the PITA Quick Guide could significantly improve how pressure injuries are treated, leading to better patient outcomes and reduced healthcare costs.
Who this helps: This helps patients with pressure injuries and the healthcare professionals treating them.
Stroke and climate change: A World Stroke Organization scientific statement.
2026
International journal of stroke : official journal of the International Stroke Society
Saad A, Khan M, Estol C, Wasay M, Kameda T +11 more
Plain English This research examines how climate change affects brain health, specifically its link to strokes. It found that exposure to cold weather, temperature changes, and extreme weather events can increase stroke risk, especially for older adults and those in low-income countries. For instance, cold temperatures were often tied to higher stroke rates, while changes in humidity and barometric pressure also play a role. Addressing climate change can help reduce these risks and improve health outcomes.
Who this helps: Patients at risk for strokes, particularly those in vulnerable populations.
Measuring progress in pregnancy planning and preconception health.
2026
Lancet (London, England)
Schoenaker D, Hall J, Verbiest S, Nonterah EA, Norman WV +14 more
Plain English This study focused on improving how we track and support pregnancy planning and preconception health across different countries. Researchers found that current methods for monitoring this vital area are lacking, as no comprehensive systems are in place, despite some progress in individual countries. They proposed a new framework that includes community input on what factors are most important before pregnancy, aiming to develop comparable indicators for monitoring health in various economic settings.
Who this helps: This benefits health policymakers and organizations working to improve care for individuals planning for pregnancy.
More equitable preconception health: paternal life course opportunities for better pregnancy, child, and family outcomes.
2026
Lancet (London, England)
Huang JY, Low FM, Kee MZL, Hopper LN, Sum KK +5 more
Plain English This study looked at how men’s health before conception affects pregnancy and family outcomes. It found that experiences during young men’s lives significantly influence both their own health and the health of their partners, emphasizing the need to consider men’s health in planning for families. This matters because it helps create fairer health practices that can improve overall family well-being, particularly for communities that have faced systemic inequalities.
Who this helps: This helps patients, especially future parents and families from marginalized communities.
A Liquid Thickener Presentation Format for the Therapeutic Management of Dysphagia-A Promising Step Forward in Addressing the Challenges Associated With Thickened Fluids in Swallowing Disorders?
2026
International journal of language & communication disorders
Ullrich N, Mossel B, Pownall S, Burke J, Perry H +2 more
Plain English This study explored a new liquid thickener called Precise Thick®N INSTANT (PTI) for people with swallowing difficulties (called oropharyngeal dysphagia or OD). Researchers found that PTI thickened drinks were significantly more enjoyable to consume, scoring an average of about 3.83 points higher on a 10-point scale than traditional powdered thickeners. This matters because it can improve hydration and quality of life for patients who have trouble swallowing, making it easier and more pleasant for them to drink liquids.
Who this helps: Patients with swallowing difficulties.
Adaptation of COMPASS for use in Autism-Specific Schools in Australia: A Cluster Randomized Trial.
2025
Journal of autism and developmental disorders
Love AMA, Cai RY, Stephenson J, Gallagher E, Toland MD +1 more
Plain English This study looked at a program called COMPASS, which helps teachers set personalized goals for autistic students in Australian schools. The researchers found that students whose teachers used the COMPASS method made more progress on their individual goals compared to those who received regular services, reporting higher satisfaction with the program. This is important because it shows that a standardized approach can greatly improve the educational experience for autistic students.
Who this helps: This benefits autistic students and their teachers.
Preconception indicators and associations with health outcomes reported in UK routine primary care data: a systematic review.
2025
The British journal of general practice : the journal of the Royal College of General Practitioners
Schoenaker D, Lovegrove EM, Cassinelli EH, Hall J, McGranahan M +5 more
Plain English This study looked at health indicators, like age and mental health status, that could affect pregnancy outcomes using data from routine UK primary care records of people aged 15-49. It found that over 20% of women had issues like being overweight, smoking, or having a history of depression, which can impact future pregnancies. Understanding these preconception health issues can help improve care and reduce risks for mothers and babies.
Who this helps: This research benefits patients planning to become pregnant and healthcare providers focused on preconception care.
International Nurse Migration Experience of the First Two Years: A Mixed Methods Study.
2025
Journal of advanced nursing
Pressley C, Newton D, Sanderson L, Simkhada B, Stephenson J +4 more
Plain English This study looked at the experiences of international nurses working in England during their first two years. Researchers surveyed 773 nurses and found that many felt their previous skills weren't fully recognized, and they faced challenges related to communication, finances, and housing. The findings emphasize the importance of support systems and better integration for these nurses to improve their well-being, which ultimately leads to better care for patients.
Who this helps: This helps international nurses and healthcare organizations.
Clinical measures in chronic neuropathic pain are related to the Kennedy and endocannabinoid pathways.
2025
European journal of clinical investigation
Bourke SL, Suarez EG, Islam B, Stephenson J, Finn DP +1 more
Plain English This study looked at people with chronic neuropathic pain (CNP) and compared their blood samples to those from people without pain. Researchers found that a gene related to fat metabolism was more active in the pain group, and a specific endocannabinoid was higher in their blood, suggesting that changes in fat processing could be linked to CNP. These findings highlight the potential for new pain treatments that target these molecular changes.
Who this helps: Patients suffering from chronic neuropathic pain.
Do Extended Reality Interventions Benefit Patients Undergoing Elective Cardiac Surgical and Interventional Procedures? A Systematic Review and Meta-analysis.
2025
Journal of clinical nursing
Harris E, Fenton S, Stephenson J, Ewart F, Goharinezhad S +2 more
Plain English This study looked at how virtual reality (VR) could help reduce anxiety in patients getting heart surgery or other procedures. They found that using VR before and during procedures significantly lowered anxiety levels - by about 1.29 points before the procedure and 0.50 points during it, compared to standard care, but it did not help with pain relief. This matters because lower anxiety can improve patient experiences and outcomes during cardiac procedures.
Who this helps: Patients undergoing elective cardiac surgeries and interventions.
A co-registration method to validateoptical coherence tomography in the breast surgical cavity.
2025
Heliyon
Sanderson RW, Zilkens R, Gong P, Boman I, Foo KY +12 more
Plain English This study looked at a method to improve how doctors check for leftover cancer cells in the area where a breast tumor was removed during surgery. Researchers used a technique called optical coherence tomography (OCT) and found that they could accurately match 78% of their scans with tissue samples taken from the surgical area, involving 16 patients. This new method helps provide a clearer picture of whether any cancer remains, which is crucial since existing methods often miss cancer that could lead to more surgeries.
Who this helps: This benefits breast cancer patients undergoing surgery by reducing the chances of needing additional procedures.
Yarning about vaccinations: Empowering individuals to have supportive conversations with Aboriginal peoples about vaccinations, using a community-engaged approach.
2025
Australian and New Zealand journal of public health
Harwood E, Taylor K, Clark K, Murray P, Stephenson J +3 more
Plain English This study looked at how effective workshops led by Aboriginal people were in improving conversations about vaccinations for Aboriginal and Torres Strait Islander communities in Hunter New England, Australia. Seventy participants attended these workshops, with most feeling more confident discussing vaccines and satisfied with what they learned. The study shows that culturally relevant education can significantly boost knowledge and confidence about vaccinations in these communities, which is important for promoting health and wellness.
Who this helps: This benefits Aboriginal and Torres Strait Islander communities and healthcare providers.
Implementing interprofessional education in the nursing and pharmacy curricula: An evaluation of a workshop focused on optimising of medicines prescribed for mental health problems.
2025
Nurse education today
Morley R, Hemingway S, Stephenson J, Astles A
Plain English This study looked at a workshop where nursing and pharmacy students learned how to work together to improve medication use for mental health issues. Out of the 70 students who attended, 93% felt they gained useful knowledge, and 94% appreciated the teamwork aspect of the event. This is important because it shows how education that fosters collaboration among future healthcare professionals can lead to better patient care.
Who this helps: This benefits patients with mental health problems by ensuring their healthcare providers can work together more effectively.
Preconception health knowledge, attitudes and behavioural intentions among adults: a multi-country study.
2025
Reproductive health
Craig A, Mabetha K, Stephenson J, Schoenaker D, Norris SA
Plain English This study looked at how much adults in five countries know about preconception health—their health before getting pregnant—and what they think about it. The researchers surveyed 5,000 adults and found that just over half (50.3%) had good knowledge about preconception health, with the US showing the best understanding (13.8% having good knowledge) and Malaysia the poorest (42.5% lacking good knowledge). These differences highlight the need for customized health programs that take into account cultural and economic factors to improve health outcomes for mothers and babies.
Who this helps: This helps patients and healthcare providers understand the importance of preconception health.
The Effects of Aerobic and Resistance Exercise on Depression and Anxiety: Systematic Review With Meta-Analysis.
2025
International journal of mental health nursing
Banyard H, Edward KL, Garvey L, Stephenson J, Azevedo L +1 more
Plain English This research examined how different types of exercise—regular aerobic activities, strength training, or a combination of both—affect people suffering from depression and anxiety. The study analyzed data from 32 trials involving over 3,200 participants and found that exercise significantly helps reduce depressive symptoms by a considerable level (-0.97) and has a moderate impact on anxiety symptoms (-0.66). This matters because it shows that incorporating exercise into treatment plans can effectively improve mental health for those affected by these conditions.
Who this helps: Patients dealing with depression and anxiety.
Unique patterns of childhood adversity and associated clinical and behavioral functioning in minority youth entering a residential program.
2025
Child abuse & neglect
Gordon CT, Nguyen PT, Heath DM, Stephenson J, Tyler PM
Plain English This study looked at the different types of difficult experiences, known as childhood adversity, that Black and Hispanic/Latinx youth face while in residential care. Researchers found five distinct patterns of adversity in Black youth and four in Hispanic/Latinx youth, with each pattern linked to specific emotional and behavioral problems. Recognizing these differences is important because it helps tailor support and treatment based on a youth's cultural background.
Who this helps: This helps patients in residential care, especially minority youth, by ensuring they receive appropriate support for their unique experiences.
A health economic analysis of 'A novel implementation of best evidence practice for incontinence-associated dermatitis' (IMBED).
2025
Journal of tissue viability
Cunich M, Barakat-Johnson M, Arora S, Church J, Lai M +13 more
Plain English This study examined the impact of a new program called IMBED, aimed at improving care for patients with incontinence-related skin issues in six Australian hospitals. The research involved 799 patients and found that after implementing the program, the use of recommended treatment products increased from 55.2% to 82.8%, while the use of less effective underpads decreased from 28.5% to 12.9%. Overall, while staff costs increased slightly due to more time spent on care, the total cost of products used dropped, indicating that hospitals could provide better care without significantly raising costs.
Who this helps: This research benefits patients with incontinence and healthcare providers by improving treatment outcomes and resource efficiency.
Quantitative analysis of stimulants in whole blood using an evaporation free precipitation salt assisted liquid-liquid extraction (SALLE) sample preparation approach.
2025
Forensic toxicology
Stephenson J, Austin J, Carney B, Flater M, Mullarkey S +1 more
Plain English This research developed and tested a new method for detecting drugs like methamphetamine and cocaine in blood samples during forensic investigations. The new technique, called SALLE, was compared to an older method and proved to be faster and just as accurate, cutting preparation time by 67% and data processing by 80%. Accurately analyzing these drugs is crucial for solving cases and understanding drug-related deaths.
Who this helps: This benefits forensic labs and law enforcement agencies dealing with drug abuse cases.
Remote Digital Health Interventions to Support the Physical, Functional, or Psychological Rehabilitation of Adult Patients With Major Traumatic Injuries: Protocol for a Systematic Review of Randomized Controlled Trials.
2025
JMIR research protocols
Al-Jabr H, Salt E, Stephenson J, Hamdan E, Helliwell T
Plain English This study is looking into how digital health tools can help adults recovering from serious injuries by improving their physical, mental, or overall rehabilitation. So far, researchers have found seven relevant studies and aim to determine how effective these remote options are for enhancing recovery outcomes. Understanding this can help healthcare providers and policy makers choose the best methods for supporting patients and improving their quality of life.
Who this helps: Patients recovering from major traumatic injuries.
iKids study protocol: a longitudinal study to understand the impact of interactive electronic devices on the development and health of young children in England.
2025
BMJ open
De Azevedo LB, Stephenson J, Hughes A, Retzler J, Reilly JJ +6 more
Plain English The iKids study looks at how the use of interactive electronic devices like tablets and smartphones affects the growth and health of children aged 3 to 5 in England. Researchers will track 1,377 children to see how much time they spend on these devices and whether they are using them for educational purposes. Early findings may help shape guidelines for parents and teachers on the best ways to use technology with young children, as the study measures important skills like social interaction, physical activity, and readiness for school.
Who this helps: This helps parents, teachers, and health professionals understand the impact of screen time on young children's development.
Plain English This study looked at the risk of dementia among older people in different regions of Nepal, involving 933 participants aged 60 and over. The research found that over half (53.7%) of them showed signs of cognitive impairment or were at risk of developing dementia, with women (56.5%) more affected than men (51.7%). This is important because it highlights the need for better healthcare services and early screening for dementia, especially in mountain and hilly areas where risks are higher.
Who this helps: This helps patients and the healthcare system in Nepal by promoting better awareness and care for those at risk of dementia.
Physical health proficiencies in mental health nursing education: Student nurses' perspectives.
2025
Nurse education in practice
Hemingway S, Shiel E, Turner J, Stephenson J, Roberts S +7 more
Plain English This study looked at how mental health nursing students in the UK feel about learning physical health skills as part of their training. Out of 115 students surveyed, most agreed that these physical health skills are important and beneficial, but they also said they want to see more practical applications of these skills within mental health settings. This matters because incorporating physical health training effectively can enhance the overall care that nurses provide to patients with mental health issues.
Who this helps: This helps nursing students and ultimately benefits patients receiving mental health care.
A cluster randomised feasibility trial assessing an interactive film intervention to improve wellbeing of young people in school settings in the North of England.
2025
Pilot and feasibility studies
Christie-de Jong F, Walker E, Corlett H, Hardarce C, Soulsby E +5 more
Plain English Researchers studied the impact of an interactive film designed to support the mental well-being of young people in schools in the North of England. The study involved 172 students from three schools, with 138 students completing follow-up questionnaires, showing that younger students (14-15 years old) were more likely to stay engaged than older students (16-17 years old). While schools were generally willing to participate, challenges like communication issues and consent processes need to be improved before a larger study can take place.
Who this helps: This benefits students in schools, particularly those dealing with mental health challenges.
Triggered: Qualitatively exploring structural and social drivers of firearm violence exposure among LGBTQ+ young adults of color in Detroit.
2025
Social science & medicine (1982)
Correll-King WM, Ubong IA, Monro D, Scott K, Strunk SN +4 more
Plain English This study looked at the reasons why LGBTQ+ young adults of color in Detroit face higher risks of gun violence. Researchers interviewed 24 people and found that racism and lack of safety were major factors; many participants viewed guns as a way to protect themselves when they felt unsafe. Understanding these issues is important for developing better safety measures and policies to help this community.
Who this helps: This helps LGBTQ+ young adults of color and those involved in creating safety policies for them.
Understanding overweight and obesity subgroups: a cluster analysis of data from the UK Yorkshire Health Study.
2025
BMC public health
O'Hara R, Stephenson J, Goyder E, Eastburn S, Jordan H
Plain English This study examined different groups of people who are overweight or obese in England to identify specific characteristics that could help create better weight management programs. Researchers analyzed data from over 47,000 people and found six distinct subgroups based on age, health, lifestyle, and mental well-being. For example, one group included younger, active women, while another involved older adults with poor health but a good quality of life. Understanding these differences is important because it can lead to more effective and personalized weight management approaches that better serve various population needs.
Who this helps: This research benefits patients struggling with weight issues by enabling more tailored support.
Advanced Practice Nurse Perceptions of Spirituality: A Global Quantitative Perspective in Everyday Life and Practice Settings.
2025
Journal of holistic nursing : official journal of the American Holistic Nurses' Association
Rogers M, Stephenson J, Ali G, Andrews C, Curran S +7 more
Plain English This study looked at how Advanced Practice Nurses (APNs) around the world view spirituality in their daily lives and work. It surveyed 641 APNs from 55 countries and found that they generally perceive spirituality as important, scoring above average in various measures related to it. Ultimately, the research emphasizes that spirituality plays a crucial role in providing full, compassionate care and suggests that APN education should focus more on integrating spirituality into their practice.
Who this helps: This information benefits patients and nurses by enhancing holistic care approaches in healthcare settings.
Can Remote Digital Health Interventions Improve Rehabilitation Following Major Trauma? Results of a Systematic Review.
2025
Archives of physical medicine and rehabilitation
Al-Jabr H, Salt E, Stephenson J, Hamdan E, Helliwell T
Plain English This research looked at whether digital health tools, like video calls and virtual reality, can help people recover from serious injuries such as traumatic brain injuries or spinal cord injuries. Out of the seven studies reviewed, three showed strong positive results, especially for spinal cord injury patients, with improvements in their physical and mental health. This is important because it suggests that using technology can enhance recovery, potentially leading to better outcomes for these patients.
Who this helps: Patients recovering from major trauma, especially those with spinal cord injuries.
Pre-Registration Mental Health Nursing Students Who Witness Self-Harm Amongst Service Users During Placement: A Cross-Sectional Study.
2025
International journal of mental health nursing
Stockton J, Lui S, Stephenson J, Hayes MC, Solomon D +2 more
Plain English This study looked at how mental health nursing students are affected when they see patients who self-harm during their training. Of the 84 students surveyed, 77% reported witnessing cutting and 74% saw head-banging, with many feeling stressed and wanting to leave their studies after these experiences. It’s important to better understand these challenges and provide training that focuses on trauma-informed care to support these students effectively.
Who this helps: This helps students in mental health nursing programs and their educators.
Recent trends in machine learning and deep learning-based prediction of G-protein coupled receptor-ligand binding affinities.
2025
Frontiers in bioinformatics
Stephenson J, Karnati KR
Plain English This research paper looked at how advancements in machine learning and deep learning can help predict how well drugs bind to specific proteins known as G protein-coupled receptors (GPCRs), which are important in drug development. It found that using different approaches—like analyzing protein sequences, molecular structures, and their spatial arrangements—can lead to better predictions, improving the odds of successful drug discovery. For example, newer models use techniques that allow for more accurate predictions without needing large amounts of pre-annotated data.
Who this helps: This benefits drug developers and researchers working on new medications.
The Variation in Practice of the Living Donor Kidney Transplant Pathway in the UK: Results of a National Survey.
2025
Transplant international : official journal of the European Society for Organ Transplantation
Nightingale K, Stephenson J, Sivaprakasam R, Brown T, Inston N +43 more
Plain English The study looked at the differences in how living donor kidney transplants are done across the UK, focusing on everything from the initial evaluation of donors to their long-term care. Researchers surveyed 23 transplant centers and found significant variations in criteria for accepting donors, which could include age limits and body weight requirements, with evaluation times ranging from 6 to 36 weeks. This matters because standardizing these processes could lead to quicker and more consistent care for donors, ultimately increasing the number of successful living donor transplants.
Who this helps: Patients needing kidney transplants and potential living donors.
The influence of human presence and footprint on animal space use in US national parks.
2025
Proceedings. Biological sciences
Gaynor KM, Hayes FP, Manlove K, Galloway N, Benson JF +63 more
Plain English This study looked at how human activity in national parks affects the movements of animals. Researchers tracked 229 animals from ten different species in 14 parks, finding that, on average, animals typically avoided areas with human presence. However, when parks were closed during the COVID-19 pandemic, animals in more developed areas began to use those spaces instead, while animals in remote areas continued to avoid humans. This research helps us understand how wildlife interacts with human activities and can inform better management of natural parks.
Who this helps: This information benefits park managers and conservationists focused on protecting wildlife.
Magnetic resonance enterography to predict subsequent disabling Crohn's disease in newly diagnosed patients (METRIC-EF)-multivariable prediction model, multicentre diagnostic inception cohort.
2025
European radiology
Taylor SA, Kumar S, Parry T, Mallett S, Travis S +28 more
Plain English This study examined whether a type of imaging called magnetic resonance enterography (MRE) could help predict if newly diagnosed Crohn's disease patients would develop severe disability from the condition within five years. The researchers followed 194 patients across nine hospitals and found that 42% of them did develop severe disability. They discovered that using MRE scores along with clinical information did not improve the ability to predict future disability risks compared to using clinical information alone.
Who this helps: This benefits patients newly diagnosed with Crohn's disease and their doctors in understanding prognosis.
Implementation of the London Measure of Unplanned Pregnancy in routine antenatal care: A mixed-methods evaluation in three London NHS Trusts.
2024
European journal of midwifery
Hall JA, Stewart C, Stoneman B, Bicknell T, Lovell H +3 more
Plain English The study looked at how the London Measure of Unplanned Pregnancy (LMUP) can be used in routine antenatal care at three hospitals in London. It found that both women and midwives found it acceptable and useful to discuss unplanned pregnancies during appointments. This approach can help tailor care to individual needs, potentially reducing risks associated with unplanned pregnancies.
Who this helps: This benefits pregnant women, midwives, and healthcare providers.
Predicted mechanistic impacts of human protein missense variants.
2024
bioRxiv : the preprint server for biology
Jänes J, Müller M, Selvaraj S, Manoel D, Stephenson J +11 more
Plain English This study looked at millions of human protein changes, focusing on how specific variants affect protein function and stability. Researchers used advanced computer modeling to analyze over 200 million variants and found around 100,000 critical areas on proteins where small molecules can bind, along with insights into protein interactions. Understanding these effects helps clarify how some variants can lead to diseases and trait differences in people.
Who this helps: This benefits patients by improving our understanding of genetic factors in diseases and helping doctors with more precise diagnoses.
Impact of an evidence-based bundle on incontinence-associated dermatitis prevalence in hospital patients: A quasi-experimental translational study.
2024
International wound journal
Barakat-Johnson M, Stephenson J, Lai M, Basjarahil S, Campbell J +11 more
Plain English This study looked at how a specific care approach affected the occurrence of skin problems caused by incontinence in hospital patients across six hospitals in Australia. Before the new care methods were put in place, about 6.7% of patients developed incontinence-associated dermatitis (IAD); after implementing the methods, that number dropped to 4.3%, showing a 36.3% reduction even amid challenging circumstances like more severe patient cases and the COVID-19 pandemic. This is important because it demonstrates that targeted education and better skin care practices can significantly help patients avoid painful skin issues while hospitalized.
Who this helps: This helps patients who experience incontinence during their hospital stay.
Factors and Perceptions Associated with Post-Pandemic Food Sourcing and Dietary Patterns among Urban Corner Store Customers in Baltimore, Maryland.
2024
Nutrients
Lewis EC, Xie Y, Sundermeir SM, Poirier L, Williamson S +6 more
Plain English This study looked at how factors like income, housing status, and race affect the eating habits of people who shop at corner stores in Baltimore, especially after the pandemic. The researchers found that 62% of participants experienced food insecurity, while 67% were overweight or obese. Many shoppers were consuming a lot of sugary drinks (about one-third of their beverage calories) and not eating enough fruits and vegetables, with only 27% getting the recommended amount of fruits and only 10% for vegetables.
Who this helps: This information is valuable for community members, local health organizations, and policymakers working to improve access to healthy food options.
What Does 'Preconception Health' Mean to People? A Public Consultation on Awareness and Use of Language.
2024
Health expectations : an international journal of public participation in health care and health policy
Schoenaker D, Gafari O, Taylor E, Hall J, Barker C +10 more
Plain English This study explored how well people understand the concept of "preconception health," which is important for improving health outcomes for future children. The researchers found that out of 54 participants, very few knew what preconception health meant and believed that using clearer, more positive language would help. Key recommendations included promoting awareness through schools and social media, and replacing complicated terms with more relatable phrases like "health before pregnancy."
Who this helps: This helps patients and future parents by improving understanding and awareness of preconception health.
Psychosocial Support for Parents, Infants, Children, and Adolescents with Variations of Sex Characteristics: Results from a Pan-European Survey.
2024
Behavioral sciences (Basel, Switzerland)
Gramc M, Monro S, Stephenson J, Streuli J
Plain English This study looked at how well parents of children with variations of sex characteristics (VSCs) are supported emotionally and socially in Europe. It found that while most healthcare professionals believe support should start when a VSC is suspected, only a small number are actually providing it. This is important because good support can help families make better choices about their child’s care and avoid unnecessary medical procedures.
Who this helps: This helps families of children with VSCs, as well as the healthcare professionals caring for them.
Inequalities in diet quality by socio-demographic characteristics, smoking, and weight status in a large UK-based cohort using a new UK diet quality questionnaire-UKDQQ.
2024
Journal of nutritional science
Roberts K, Stephenson J, Holdsworth M, Relton C, Williams EA +1 more
Plain English This study looked at how different factors like gender, smoking, and weight affect the quality of people's diets in Yorkshire and Humber, UK, using data from over 43,000 adults. It found that on average, women had better diets than men, and non-smokers scored higher than smokers, with a difference of about 4 points in diet quality scores. The study highlights that those with lower income, younger people, and people classified as overweight tend to have poorer diets, which matters because it shows groups that may need more support to improve their eating habits.
Who this helps: This helps patients and public health officials working on nutrition and health interventions.
Strengthening Community Responses to Economic vulnerability (SeCuRE): a protocol of an HIV status-neutral pilot randomized clinical trial with transgender women of color in Detroit, Michigan.
2024
Pilot and feasibility studies
Gamarel K, Mayo-Wilson LJ, Jadwin-Cakmak L, Reyes L, Monro D +11 more
Plain English This study looks at how financial support and training can help transgender women of color in Detroit who face poverty and high rates of HIV. The research tested two different approaches: one group received standard aid that included $250 in emergency funds and peer support, while another group got additional help, including 12 weeks of job training and a $1200 grant for employment. The findings could pave the way for larger trials that aim to effectively reduce HIV disparities among this vulnerable group.
Who this helps: This helps transgender women of color who are at risk for economic hardship and HIV.