Dr. Breaux studies the intersection of environmental factors and public health, particularly how socio-economic conditions affect disease spread and health outcomes. He has conducted research on mosquito populations linked to discarded tires in low-income neighborhoods, revealing how these areas may be more vulnerable to diseases spread by mosquitoes. In addition, he has explored treatments for complex medical conditions, such as a rare lung cancer and Clostridium difficile infections, emphasizing the importance of early diagnosis and effective treatment options.
Key findings
In neighborhoods with lower income, higher tire abundance led to increased populations of Aedes albopictus mosquitoes, indicating a greater risk for mosquito-borne diseases.
The fecal microbiota transplantation (FMT) treatment for Clostridium difficile infections showed a success rate of 93%, with all 20 patients in the study completely cured, and no recurrence of the infection.
Women participating in the SmartMoms program had only 56% and 58% exceeding recommended weight gain, compared to 85% in the usual care group, demonstrating the program's effectiveness in managing gestational weight gain.
Frequently asked questions
Does Dr. Breaux study mosquito-borne diseases?
Yes, Dr. Breaux investigates how environmental factors, such as discarded tires, contribute to mosquito populations that spread diseases in areas like New Orleans.
What treatments has Dr. Breaux researched?
Dr. Breaux has researched various treatments, including fecal microbiota transplantation for Clostridium difficile infections and flibanserin for improving sexual desire in women.
Is Dr. Breaux's work relevant to pregnant women?
Yes, his research includes programs like SmartMoms, which help pregnant women manage weight gain, important for their health and that of their babies.
How does Dr. Breaux's research help children?
His studies highlight the negative effects of food insecurity and poverty on child development, advocating for better nutrition initiatives to support healthy growth.
Can Dr. Breaux's research help patients with complex diagnoses?
Absolutely, Dr. Breaux's work on timely diagnosis in conditions like pulmonary artery intimal sarcoma is crucial for improving patient outcomes and survival rates.
Publications in plain English
Spindly reason for a pulmonary embolism.
2024
BMJ case reports
Goldberg A, Chen JN, Breaux J, Pope H
Plain English This study looked at a rare type of cancer called pulmonary artery intimal sarcoma (PAIS), which can be confused with blood clots in the lungs. The researchers shared a case where a patient with PAIS was misdiagnosed but received timely treatment, which is crucial for improving survival rates. Rapid and correct diagnosis is key because these tumors are often mistaken for less serious conditions, leading to delays in effective treatment.
Who this helps: This benefits patients who may have PAIS, as well as healthcare providers diagnosing lung-related issues.
Discarded vehicle tires and their association with mosquito vector abundance across socioenvironmental gradients in New Orleans, LA.
2024
Journal of medical entomology
de Jesús Crespo R, Pavlakis A, Breaux J, Riegel C
Plain English This study looked at how discarded vehicle tires can influence mosquito populations in New Orleans, particularly focusing on social factors like income and population density. Researchers found that neighborhoods with lower income and higher tire abundance had more Aedes albopictus mosquitoes, which are known to spread diseases. This is important because it highlights that poorer neighborhoods may face a higher risk of mosquito-borne diseases due to the accumulation of tires, and it suggests where efforts to reduce mosquito breeding could be focused.
Who this helps: This helps low-income residents and public health officials.
Oviposition preferences of the mosquitoLinnaeus, 1762 (Culicidae): an urban environment bioassay.
2019
Bulletin of entomological research
Kroth N, Cozzer GD, de Carvalho G, Cassol AS, Breaux J +5 more
Plain English This study looked at how the urban mosquito Aedes aegypti chooses where to lay its eggs, focusing on both indoor and outdoor locations and the amount of organic matter in the water. The researchers found that mosquitoes preferred to lay eggs outdoors, especially in water with higher levels of organic matter, particularly during the later weeks of the study. Understanding these preferences is important because it helps us manage mosquito populations in urban areas and reduce the spread of diseases they may carry.
Who this helps: This information benefits public health officials and urban planners in controlling mosquito breeding.
Effectiveness of SmartMoms, a Novel eHealth Intervention for Management of Gestational Weight Gain: Randomized Controlled Pilot Trial.
2017
JMIR mHealth and uHealth
Redman LM, Gilmore LA, Breaux J, Thomas DM, Elkind-Hirsch K +12 more
Plain English This study looked at a program called SmartMoms aimed at helping pregnant women manage their weight gain during pregnancy. They found that women using the SmartMoms program had lower rates of exceeding recommended weight gain: only 56% of those in the in-person group and 58% in the remote group exceeded guidelines, compared to 85% in the usual care group. The program was also cheaper to participate in and led to higher adherence than traditional care, which is important as managing weight gain effectively can lead to better health outcomes for mothers and babies.
Who this helps: This helps pregnant women, especially those who are overweight or obese.
MISSING THE OBVIOUS: A CASE OF UNDIAGNOSED GRAVES' DISEASE.
2015
The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society
Shum K, Lu J, Breaux J, Dendy J
Plain English This research focused on Graves' disease, a condition that causes an overactive thyroid, which often goes undiagnosed in about 3.4% of people. The lack of treatment for this disease can lead to serious health issues, including heart problems and life-threatening crises. Detecting and treating Graves' disease early is crucial to preventing these severe complications.
Who this helps: This benefits patients who may have undiagnosed Graves' disease and their doctors, who can provide better care.
Fecal Microbiota Transplantation for Clostridium difficile Infection: The Ochsner Experience.
2014
Ochsner journal
Ray A, Smith R, Breaux J
Plain English This study looked at how well fecal microbiota transplantation (FMT) works to treat Clostridium difficile infections (CDI), which are a serious cause of diarrhea, especially in hospitals. They treated 20 patients, aged 27 to 89, and found that FMT completely cured them, with no cases of CDI returning after treatment. This is significant because FMT has a high success rate of 93%, and it shows that this treatment is safe and effective for people suffering from recurrent and severe CDI, especially when traditional antibiotics are not working.
Who this helps: This helps patients with recurrent Clostridium difficile infections.
Plain English This study looked at how medical residents transfer information about patients when they switch shifts. Researchers found that while many faculty members recognized problems with these handoffs, 72% said they had identified patient safety issues because of them, and 80% of residents felt they didn’t get enough feedback on their handoff processes. This matters because creating a standardized way to share patient information can help improve training for residents and enhance patient safety.
Who this helps: This helps patients and medical residents.
Drug delivery to the posterior segment of the eye through hydrogel contact lenses.
2011
Clinical & experimental optometry
Schultz C, Breaux J, Schentag J, Morck D
Plain English This study looked at how hydrogel contact lenses can deliver medications to the back part of the eye. Researchers found that these lenses successfully released steroids into the eye, with one drug (prednisolone) found in all six rabbits tested, reaching amounts between 26.8 and 166 nanograms per gram of tissue. This is important because it offers a new, non-invasive way to treat eye conditions that affect the back of the eye, potentially improving patient care.
Who this helps: This benefits patients with eye diseases that require treatment in the posterior segment of the eye.
Continued efficacy and safety of flibanserin in premenopausal women with Hypoactive Sexual Desire Disorder (HSDD): results from a randomized withdrawal trial.
2011
The journal of sexual medicine
Goldfischer ER, Breaux J, Katz M, Kaufman J, Smith WB +3 more
Plain English This study focused on a medication called flibanserin, which aims to improve sexual desire in premenopausal women with Hypoactive Sexual Desire Disorder (HSDD). After 24 weeks of treatment, women taking flibanserin experienced about twice as many satisfying sexual events and significant increases in sexual desire and function compared to those on a placebo. At the end of the study, women on flibanserin showed better results in several key areas related to sexual health, with no significant side effects reported.
Who this helps: This benefits premenopausal women suffering from HSDD who are seeking effective treatment options.
Witnesses to hunger: participation through photovoice to ensure the right to food.
2009
Health and human rights
Chilton M, Rabinowich J, Council C, Breaux J
Plain English This study examined the issue of food insecurity, which affects 30.2% of female-headed households with children in the U.S., meaning many families don’t have enough food for a healthy life. It focused on the Witnesses to Hunger program, where low-income mothers share their experiences of poverty and hunger through photos and stories, helping to influence social policies related to nutrition and poverty. This matters because involving these mothers in decision-making can lead to better policies that support their families and enhance child well-being.
Who this helps: This helps low-income mothers and their children who face food insecurity.
The negative effects of poverty & food insecurity on child development.
2007
The Indian journal of medical research
Chilton M, Chyatte M, Breaux J
Plain English This paper studies how poverty and lack of access to nutritious food negatively affect the development of young children, particularly in their first three years of life. It found that even small amounts of food insecurity can significantly harm a child's ability to grow, learn, and thrive, leading to a cycle where future generations remain in poverty. Addressing these issues through better nutrition initiatives and support systems is essential to ensure that children have the best chance for healthy development and a brighter future.
Who this helps: This helps young children living in poverty, their families, and policymakers focused on child welfare.
L-selenomethionine modulates high LET radiation-induced alterations of gene expression in cultured human thyroid cells.
2006
Oncology reports
Stewart J, Ware J, Fortina P, Breaux J, Gulati S +1 more
Plain English This study focused on the protective effects of a compound called L-selenomethionine (SeM) against radiation damage in thyroid cells. Researchers exposed these cells to different levels of radiation and found that SeM notably changed gene expression in response to this radiation, highlighting its potential to prevent cell death and transformation caused by radiation. Specifically, SeM had a significant impact on how these cells reacted to radiation, which is crucial for understanding how to protect people from radiation-related damage.
Who this helps: Patients undergoing radiation treatment and those exposed to radiation in space or other environments.
Randomized, double-blind comparison of once-weekly dalbavancin versus twice-daily linezolid therapy for the treatment of complicated skin and skin structure infections.
2005
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Jauregui LE, Babazadeh S, Seltzer E, Goldberg L, Krievins D +6 more
Plain English This study compared two treatments for serious skin infections: dalbavancin, given once a week, and linezolid, taken twice a day for 14 days. Both treatments worked well, with about 89% of patients on dalbavancin and 91% on linezolid showing improvement after treatment. The results are important because they show that dalbavancin is just as effective as linezolid, but with fewer doses and better tolerability for patients, especially those with infections caused by hard-to-treat bacteria like MRSA.
Who this helps: This helps patients with complicated skin infections, particularly those dealing with MRSA.
The Breaux Plan: a radically centrist approach to a new health care system.
2003
Health affairs (Project Hope)
Breaux J
Plain English This paper discusses a new health care plan proposed by Senator John Breaux that combines the best ideas from both private and public health insurance systems. The plan aims to ensure everyone has access to health insurance by having the government set basic standards and support state-run insurance for those in need, while also allowing private companies to compete and offer coverage. This is important because it would hold Americans responsible for getting health insurance and provide help in securing it for the first time.
Who this helps: This benefits all Americans who need health insurance, especially those who are vulnerable or have low income.
Plain English The paper discusses the process of creating a health care reform proposal by President Bill Clinton, which was shared with Congress and the public last fall. It included interviews with 11 Congress members who represent different viewpoints, shedding light on how they feel about the reform and what might happen next. This is important because it shows the diverse opinions in Congress that will shape the final health care reforms for the country.
Who this helps: This benefits patients and their families by potentially improving health care access and quality.
Plain English This study looked at the effectiveness of using a mixture of iodized talc to treat pleural effusions, which are fluid buildups in the space around the lungs. Out of 34 patients treated, all showed clear improvement with no recurrences of fluid buildup after treatment, even when some experienced worsening of their cancers. This matters because it shows that iodized talc pleurodesis is a safe and effective way to manage both cancer-related and non-cancer-related pleural effusions.
Who this helps: Patients with pleural effusions, especially those with cancer.