JOHN GIBBS, MD

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This study looked at how trauma-informed care (TIC) can be integrated into online sexual health services in England. Researchers talked to 125 users of these services, finding that many felt more comfortable using online self-sampling for sexual health testing because it offered them privacy and control. However, some users were still worried about sharing sensitive information online and felt there wasn't enough support for trauma survivors, highlighting areas that need improvement. Who this helps: This benefits patients, especially those who have experienced trauma.

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This study looked at how well remote consultations work for sexual and reproductive health services, especially because of funding cuts and changes from COVID-19. Out of nearly 8,700 studies reviewed, 48 were included, showing that while remote consultations can be convenient, they also highlight existing issues like access to technology and communication, which can increase inequalities. The research emphasizes the need for better quality studies that focus on making these services fairer and more accessible for everyone in the future. Who this helps: This helps patients who need sexual and reproductive health services, particularly those facing barriers to access.

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This study looked at how to improve treatment for acute myeloid leukemia (AML), particularly for patients who stop responding to the drug venetoclax. Researchers tested a combination of venetoclax and another drug called palbociclib in 302 patient samples and found that this combination was very effective, leading to better responses in cancer cells. Specifically, they discovered that when certain genes related to protein production were downregulated, the combination worked even better, helping to overcome resistance that often develops with standard treatments. Who this helps: This research benefits patients with acute myeloid leukemia who are resistant to current therapies.

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This study looked at how taking whey protein right after intense running affects certain proteins in the blood that are linked to bone health and inflammation in endurance runners. The research involved 14 runners who consumed either whey protein or water after exercising, but the results showed that the protein didn't change the levels of these blood markers compared to the water, even though some markers increased after exercise and returned to normal after 24 hours. This is important because it helps clarify that just adding protein after a workout doesn't seem to help with bone injuries or inflammation in these athletes. Who this helps: This helps endurance runners by providing insight into their recovery strategies.

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This study looked at how healthcare workers handle the mental health needs of young patients in hospitals, especially those focuses on physical health. Researchers interviewed 31 professionals and found that both groups felt overwhelmed and unprepared to address mental health issues, with many reporting difficulties in managing serious conditions like self-harm and eating disorders. They highlighted the pressing need for better training and resources to provide safe and effective care for these young patients. Who this helps: This benefits young patients with mental health needs and the healthcare workers caring for them.

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This paper discusses how the pathology field can better use artificial intelligence (AI) to improve patient care by establishing clear standards. The authors held discussions with leaders in healthcare and found that implementing AI successfully depends on consistent practices across the field. They emphasize that defining standards can lead to greater efficiency and effectiveness in using AI, which ultimately benefits patient diagnosis and treatment. Who this helps: This helps patients and healthcare providers by improving the accuracy and speed of pathology diagnoses through AI.

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This study focused on improving follow-up colonoscopies for patients with abnormal fecal immunochemical test (FIT) results, which are important for reducing colorectal cancer risks. Researchers found that many patients do not complete these colonoscopies, but with a patient navigation program (PN), they could successfully guide more people to finish the process. The program showed promise, helping to clarify how to implement and support patient navigation effectively in community health centers. Who this helps: This benefits patients at risk of colorectal cancer by ensuring they receive necessary follow-up care.

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This research looked at how plant-based diets affect levels of C-reactive protein (CRP), a marker of inflammation linked to heart disease. Out of nearly 3,000 studies reviewed, seven clinical trials with 541 participants showed that those on plant-based diets had an average CRP reduction of 1.13 mg/L compared to those eating meat. This matters because lowering CRP levels can reduce the risk of age-related diseases and heart problems. Who this helps: This helps patients looking to manage inflammation and improve their heart health.

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This paper corrects earlier findings about how implementing online postal self-sampling for sexually transmitted infection (STI) testing in England affected patient outcomes. The study analyzed service-level healthcare data and found notable improvements in STI detection rates, showing that more people were tested effectively after the online program started. This matters because it indicates that making testing more accessible can lead to earlier detection and treatment of infections, benefiting public health. Who this helps: Patients seeking convenient and effective STI testing.

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This study looked at the effects of a new online postal self-sampling system for sexually transmitted infection (STI) testing in England, comparing testing rates before and after its implementation from 2015 to 2022. The findings revealed significant increases in testing: chlamydia and gonorrhea testing rates increased by 2.1 to 2.5 times, and HIV testing rates rose by 1.5 to 2.8 times in different areas after the new system was introduced. However, people in more deprived areas showed the lowest increase in testing, which highlights the need to ensure everyone knows about and can access this service equally. Who this helps: This benefits patients, especially those needing STI testing, and helps health services understand how to improve access for all groups.

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This study looked at how underserved groups access online consultations for chlamydia treatment and identified challenges they face, including concerns about privacy and unfamiliarity with online services. The researchers interviewed 35 participants, finding that over half were from deprived areas and 40% were from minoritized ethnic groups. They proposed strategies to make these online consultations easier and safer to use, such as improving awareness, simplifying language, and enhancing support. Who this helps: This helps patients, particularly those from underserved communities seeking sexual health care.

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This study assessed an online service for testing sexually transmitted infections (STIs) in London, known as Sexual Health London (SHL), over four years. Among 670,293 users, there were nearly 1.5 million orders for STI tests, with 79.5% returning chlamydia and gonorrhea tests, and 67.6% for HIV tests. The study found that 4.5% of chlamydia tests and 1.6% of gonorrhea tests came back positive, indicating a lower rate of infections compared to national averages, which might be due to the focus on asymptomatic screening before 2020. Who this helps: This benefits patients seeking STI testing, particularly those who prefer online services.

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This study explored how people from underserved communities in the UK find and use online sexual health information and support. Researchers interviewed 35 participants, discovering that many faced barriers like a lack of awareness and overwhelming information, while beneficial factors included clear, credible resources and personal assistance. The recommendations made—such as better education on online resources and simplifying access—aim to make it easier for these populations to seek sexual healthcare online, ultimately helping to reduce healthcare inequalities. Who this helps: This helps patients from underserved communities who struggle to access sexual health information and services online.

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This study looked at how people in Britain could collect samples for testing sexually transmitted infections (STIs) at home, particularly focusing on vaginal swabs. Out of 261 participants, 161 agreed to provide samples, and 129 actually submitted them, with 77% of the women providing vaginal swabs. This matters because it shows that self-collection is a practical and acceptable method for STI testing, especially significant as the country recovers from the COVID-19 pandemic and seeks to improve sexual health survey participation. Who this helps: This benefits patients by making STI testing more accessible and convenient.

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This study looked at a new treatment for high-risk ductal carcinoma in situ (DCIS), a type of breast cancer. Researchers tested a combination of two medications, pembrolizumab and mRNA-2752, administered directly into the tumors of 10 women. They found that 8 out of 10 patients responded positively to the treatment, with 3 patients showing complete cancer remission and avoiding surgery for over a year. Who this helps: This benefits women with high-risk DCIS, particularly those who may want to avoid more invasive surgeries.

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This study looked at how young adults with psychosis feel about their treatment and their communication with family members. Researchers interviewed 12 people diagnosed with a psychotic disorder in the last five years. They found that strong relationships with mental health workers and good communication with family are key to staying engaged in treatment. Who this helps: This benefits young adults with psychosis and their families.

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This study looked at two species of bees from the mountains of Mexico and Central America, specifically Lasioglossum (Eickwortia) hienae and L. (E.) alexanderi, which had only been known as females until now. Researchers found and described the males of these species for the first time and shared new information on where they can be found. This discovery is important because it helps improve our understanding of these bees and how to identify them. Who this helps: This benefits researchers and conservationists studying bees and biodiversity.

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This research looked at how child welfare workers make decisions about cases of neglect and found that factors in their work environment significantly impact those decisions. Specifically, it showed that heavy workloads and stress can make neglect a lower priority for action. Also, a lack of support services affects when intervention occurs, meaning increased investment and better training could lead to quicker and more effective help for neglected children. Who this helps: This helps child welfare workers and the children they protect.

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This study looked at whether providing support, called patient navigation, helps adults who had an abnormal stool test complete their follow-up colonoscopy. Researchers found that 55.1% of those who received navigation went on to get the colonoscopy, compared to only 42.1% of those who received standard care—showing a 13% increase in completion rates. This matters because more people getting their colonoscopies can lead to earlier detection of issues, potentially saving lives. Who this helps: Patients who need follow-up care after abnormal stool test results.

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This study explored how adults in Britain use pornography, their reasons for using it, and how they deal with the stigma attached to it. Out of 40 participants, 34 had used pornography, with 18 using it regularly, mainly for personal arousal, mood enhancement, or sexual exploration. Many felt the pressure of stigma, so they hid their use or distanced themselves from negative views about it, which can hinder discussions about healthy use and access to help when needed. Who this helps: This research benefits patients and educators who address issues related to pornography and sexual health.

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The study looked at how the Hospital Harmony program affects teamwork and communication among healthcare staff in a busy hospital setting. Researchers found that after participating in the 6-week program, team members reported significant improvements: meeting effectiveness increased by 40%, team morale went up by 80%, and feelings of safety and focus improved as well. This is important because better communication and teamwork lead to better patient care. Who this helps: This helps healthcare staff and ultimately benefits patients receiving treatment.

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This study focused on a new drug called TAK-981, which targets a specific enzyme to boost immune responses in cancer treatment. Researchers developed a reliable method to measure the amount of TAK-981 in human blood, finding it effective at concentrations ranging from 0.1 to 100 ng/mL. This advancement is important because it helps in tracking the drug's levels during clinical trials, ensuring its effectiveness and safety. Who this helps: This benefits patients participating in clinical trials for cancer treatments.

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This research studied a new type of material called Atums Green (AG), which is a conjugated polymer designed to detect blue light, particularly in the 450 nm range that is important for many devices like smartphones and computers. The researchers found that adding a low-cost waste product, asphaltene, improved the sensitivity of the blue light detector. This matters because having better blue light sensors can help with safety and technology applications including screen displays and environmental studies. Who this helps: Patients and consumers using devices that emit blue light.

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This study looked at the use of corticosteroids before administering infliximab (IFX) in patients with inflammatory bowel disease (IBD). Researchers found that from 2015 to 2020, the percentage of patients receiving corticosteroid premedication dropped from 27.4% to 20.4%, but 38.7% of those who were premedicated still received it for more than 90% of their infusions, often without a prior reaction to justify its use. This is important because unnecessary corticosteroid use can lead to serious health issues, and reducing it could improve patient safety and health outcomes. Who this helps: Patients with inflammatory bowel disease.

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This study looks at safety issues related to all-terrain vehicles (ATVs) in agriculture, focusing on reducing injuries and deaths, especially for young riders. Experts from five countries highlighted key problems, such as the instability of ATVs and the need for better training and protective gear. They propose solutions like improved vehicle designs and stricter regulations to make riding safer. Who this helps: This benefits farmers, young ATV riders, and safety advocates.

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The study examined how remote consultations, like phone or video appointments, are used in sexual and reproductive health services in the UK. It found that the available guidance on these consultations is limited and often based on weak evidence. Although remote options could increase access for some patients, challenges like unequal access to technology and varying levels of digital skills remain significant. This research emphasizes the need for better, evidence-based guidelines that take into account the needs of all patients. Who this helps: This benefits patients seeking sexual and reproductive health services, especially those in disadvantaged groups.

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This study examined how the lack of a protein called IL-23 affects oral mucositis (OM) in cancer patients who receive radiation therapy for head and neck cancers. The researchers found that while mice without IL-23 didn't show extra damage to their oral tissue from radiation, they did experience much worse problems when they also had a fungal infection, making them more vulnerable. Specifically, those mice had dramatically increased susceptibility to the fungal infection when IL-23 was absent, which highlights the importance of this protein in protecting against oral infections after radiation treatment. Who this helps: This helps cancer patients undergoing radiation treatment, particularly those at risk for oral infections.

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This study looked at how many people in England are using online postal self-sampling (OPSS) for chlamydia tests instead of going to a clinic. Between 2015 and 2022, the number of tests done through OPSS rose significantly from 2.6% to 38.4% of all tests. However, people from poorer areas were less likely to use this method, and the positivity rate for chlamydia was lower with OPSS compared to in-person testing. Who this helps: This benefits patients, especially those seeking more convenient testing options.

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This study examined how online postal self-sampling (OPSS) for sexually transmitted infections (STIs) was implemented in three areas of England. Researchers interviewed 60 staff and stakeholders and reviewed 86 documents, finding that OPSS was influenced by changes in local health systems and financial pressures, with outcomes varying widely due to different regional approaches. For example, the COVID-19 pandemic sped up OPSS adoption in some areas while slowing it down in others, highlighting that these implementations were ongoing processes shaped by changing contexts. Who this helps: This research helps healthcare providers and policymakers improve STI screening services for patients.

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This study looked at how people living with HIV in the UK feel about tracking and sharing their personal health data using digital tools. Researchers interviewed 24 individuals, including patients and healthcare providers, and found that while tracking health data can help patients gain more control and improve their relationships with doctors, it can also be burdensome and raise privacy concerns. Overall, it highlights the need to balance the benefits of data sharing with the challenges that come with it, especially as digital healthcare becomes more common. Who this helps: This study benefits patients with HIV and their healthcare providers.

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This study looked at a type of immune cell called resident memory T (Trm) cells in macaques and how they respond to vaccination against a virus similar to HIV. Researchers found that after vaccination, these Trm cells were activated in over 30 different tissues, including in the reproductive system, and they helped to recruit other immune cells and enhance the body’s defense mechanisms against infections. This is important because it shows that vaccines can effectively stimulate a strong immune response in key areas of the body that might be vulnerable to infections. Who this helps: This research benefits patients at risk for viral infections, particularly in the reproductive tract.

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This study looked at how disabled people in Britain struggled to access sexual and reproductive health services during the first year of the COVID-19 pandemic. It found that 23% of disabled participants wanted to access these services but were unable to, compared to a much lower rate among those without disabilities. This matters because it highlights a significant gap in healthcare access for disabled individuals, which could lead to longer-term health issues and unmet needs. Who this helps: This benefits disabled individuals seeking sexual and reproductive health services.

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This study looked at the costs and benefits of taking X-rays after minimally invasive bunion surgery. Out of 245 patients, only four (1.6%) had X-ray results that led to a change in their treatment, meaning most X-rays did not provide useful information. Since routine X-rays can add significant costs—estimated between $3.5 million and $23.3 million a year for these procedures—eliminating them when not needed could save money in healthcare. Who this helps: This helps patients and healthcare providers by reducing unnecessary costs and focusing on more effective evaluations.

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This study examined the differences in sexual and reproductive health outcomes among women aged 16-24 in England from 2012 to 2019. The researchers found that women in poorer areas had significantly lower testing rates for chlamydia (65% lower) and gonorrhoea (21% lower), as well as lower abortion rates (55% lower) compared to those in more affluent areas. Additionally, black women had higher rates of positive tests for chlamydia (24% higher) and gonorrhoea (92% higher) and repeat abortions (31% higher) compared to white women. This matters because it highlights persistent inequalities that affect the health of young women, particularly those from deprived and racially minoritised backgrounds, and emphasizes the need for targeted health interventions. Who this helps: This helps young women, especially those from disadvantaged and racially minoritised communities.

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This study focused on understanding "unmet need" in sexual and reproductive health (SRH) services in England by gathering insights from professionals in the field. Researchers found that many experts believe that addressing unmet needs is crucial for improving SRH services, with concerns that specific groups aren't well represented in current data. The experts emphasized that including input from affected communities and using qualitative research methods are essential to fully grasp the complexities of unmet needs and enhance service delivery. Who this helps: Patients and vulnerable populations seeking better access to sexual and reproductive health services.

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This research looked at how digital tools can help individuals notify their sexual partners about sexually transmitted infections (STIs) and HIV. Out of 26 studies reviewed, many people preferred face-to-face notifications, especially for serious relationships, but digital methods were appreciated for notifying casual partners. This matters because using digital methods can improve notification and management of STIs and HIV, leading to better health outcomes. Who this helps: Patients and healthcare providers involved in STI and HIV management.

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This study looked at how effective Brain Gym exercises are compared to cognitive behavioral therapy (CBT) for improving sleep quality among healthcare university students, many of whom struggle with sleep. After four weeks, the students who did Brain Gym exercises showed a bigger improvement in their insomnia and sleep quality scores than those who received CBT; Brain Gym participants had scores of 20.55 for insomnia severity (ISI) and 18.09 for sleep quality (PSQI), while CBT participants had scores of 19 and 16.64, respectively, with both methods being significant. These findings suggest that Brain Gym exercises might be a helpful, non-drug option for students dealing with sleep problems. Who this helps: This benefits healthcare university students facing sleep issues.

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This study examined a woman who developed postpartum psychosis, a serious condition that can affect new mothers, specifically focusing on her experience of misidentification delusions in the hospital. She recovered quickly with medication and did not have any relapses over the next three years. Her detailed accounts revealed key insights into what triggered her delusions and how social factors influenced her beliefs, showing that delusions can be complex and challenging current understanding of how they form. Who this helps: This benefits new mothers experiencing postpartum psychosis and mental health professionals treating them.

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This study looked at how dentists in the American Association of Endodontists have been using regenerative endodontic procedures from 2008 to 2019. Out of nearly 1,000 survey responses, they found that 55% of the cases were considered successful, and most patients were boys around 10 years old who had dental injuries. The findings highlight a wide range of techniques used and show that as time goes on after treatment, improvements in tooth structure are common, pointing to a need for better and more consistent treatment protocols. Who this helps: This helps dentists understand effective practices for treating dental injuries in children.

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This study examined bee populations at a nature preserve in southern Michigan over nearly a century, comparing data from 1921 to 2018. Researchers found that the number of bee species dropped from 135 in the 1970s to just 90 in recent years, with 64% of common species decreasing by over 30%. This decline in bee diversity and abundance indicates significant ecological changes, potentially linked to climate impacts, which could affect pollination and plant growth in the area. Who this helps: This benefits conservationists and environmental scientists working to protect bee populations and ecosystems.

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This study examined how people use an online postal self-sampling service for testing sexually transmitted infections (STIs) and what influences their decision to choose this option over visiting a clinic. Researchers interviewed 100 users and found that many prefer self-sampling because it offers more privacy and helps them avoid barriers like long wait times at clinics. While this method was generally easy to use, participants still valued the additional support clinics provide for more complex health concerns. Who this helps: This research benefits patients seeking STI testing and healthcare providers looking to improve access to sexual health services.

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This study looked at who was able to get sexually transmitted infection (STI) testing in Britain during the COVID-19 pandemic, focusing on how people accessed these services. Out of over 6,000 people, only 246 (about 4.2%) reported getting tested for STIs between March 2020 and March 2021, and of those, 35.8% used online services. The findings revealed that online testers tended to be healthier and more likely to be white compared to those who used other, in-person testing methods, indicating that online options may be primarily benefiting lower-risk groups. Who this helps: This helps patients seeking STI testing, especially those with lower health risks.

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This study focuses on preventing suicide-related behaviors in veterans after they leave psychiatric hospitals. Researchers are testing a new program called CLASP, which involves follow-up support for high-risk patients, compared to standard care. They enrolled 850 veterans, expecting to find that those receiving CLASP will have fewer suicide-related issues over six months. Who this helps: This research benefits high-risk veterans and their healthcare providers.

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This study looked at how different types of bees visit a rare flower called Silene spaldingii, which is primarily pollinated by a bumble bee called Bombus fervidus. Researchers found that out of 2211 bees captured, only about 11% visited S. spaldingii, with sweat bees being significant visitors; some species were even recorded for the first time in the Americas. This is important because understanding the role of these co-pollinators could help protect both the flower and the bees, especially if the bumble bee numbers keep dropping. Who this helps: This information benefits conservationists and environmentalists working to protect rare plants and their pollinators.

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This study looked at how certain genetic markers in mothers affected the way they interact with their infants and how those infants process sensory information. Researchers found that mothers with a specific genetic variant were more emotionally connected with their babies, while another genetic variant was linked to different interaction patterns. Babies of mothers with one genetic marker were 11 times more likely to have trouble with sensory processing, which is important for their development. Who this helps: This helps mothers and their infants by providing insights into how genetics can affect their interactions and the baby's sensory development.

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This study looked at a rare type of cancer called dedifferentiated liposarcoma (DDL) that can form in the upper limbs and has a unique hard bone-like part. The researchers described one unusual case where this DDL included a hard, bony component, which is not often seen. Understanding these rare cases is important because it can help doctors better diagnose and treat patients with unusual cancer profiles. Who this helps: This benefits patients with dedifferentiated liposarcoma and their doctors.