DR. JOHN C. LINZ, M.D.

CINCINNATI, OH

Research Active
Orthopaedic Surgery - Foot and Ankle Surgery NPI registered 21+ years 14 publications 1979 – 2019 NPI: 1053316315
PlantsTemperatureVolatile Organic CompoundsFeeding BehaviorDose-Response Relationship, DrugFood MicrobiologyDrosophilaConsumer Product SafetyColony Count, MicrobialAflatoxinsAspergillusCenters for Medicare and Medicaid Services, U.S.AcetoinAnomuraIndian Ocean Islands

Practice Location

4355 FERGUSON DR
CINCINNATI, OH 45245-5136

Phone: (513) 232-2663

What does JOHN LINZ research?

Dr. Linz focuses on understanding how different organisms interact with their environments, particularly concerning their sensory perceptions and responses to various stimuli. He studies everything from how fruit flies detect smells to the impact of plant diversity on insect populations. Additionally, his research includes exploring how bacteria respond to stress and how these responses affect their resistance to antibiotics and sanitizers. This work is crucial as it relates to agriculture, food safety, and insights into managing diseases caused by pathogens.

Key findings

  • Giant robber crabs preferentially respond to acetoin, indicating it is the strongest attractant among 15 tested odors.
  • 48% of Campylobacter isolates from organic farms and 58% from conventional farms showed resistance to tetracycline, highlighting a widespread antibiotic resistance in bacteria from the food supply.
  • Grasshoppers laid more eggs in areas with diverse plant species, pointing to a direct correlation between plant variety and insect reproductive success.

Frequently asked questions

Does Dr. Linz study the effects of plant diversity on insects?
Yes, he has researched how different plant species affect the reproductive success of grasshoppers.
What pathogens has Dr. Linz researched?
He has studied the plant pathogen Ralstonia solanacearum and its chemical production, which impacts crop health.
Is Dr. Linz's work relevant to foodborne illnesses?
Yes, his research on antibiotic resistance in Campylobacter bacteria is crucial for understanding foodborne infections.
What discoveries does Dr. Linz have regarding fruit flies?
He has found that fruit flies have specialized senses to detect harmful microbes and food sources, which influence their behavior.
How does Dr. Linz's research help improve food safety?
His studies on the sensitivity of bacteria to sanitizers and mycotoxin inhibition contribute to safer food processing and agriculture.

Publications in plain English

Acetoin is a key odor for resource location in the giant robber crab.

2019

The Journal of experimental biology

Knaden M, Bisch-Knaden S, Linz J, Reinecke A, Krieger J +3 more

Plain English
Researchers studied how giant robber crabs find food on islands, focusing on their attraction to different odors from coconuts and arenga fruit. They discovered that out of 15 different smells tested, acetoin was the only one that strongly attracted the crabs. This finding is important because it shows how a specific scent can draw these crabs together to food, which can help us understand their behavior and ecology. Who this helps: This benefits ecologists and wildlife researchers studying crab behavior and island ecosystems.

PubMed

Host plant-driven sensory specialization in Drosophila erecta.

2013

Proceedings. Biological sciences

Linz J, Baschwitz A, Strutz A, Dweck HK, Sachse S +2 more

Plain English
This study looked at how the sense of smell in the fruit fly Drosophila erecta has evolved to help it find its preferred food, screw pine fruits. Researchers found that D. erecta is particularly good at detecting a specific scent called 3-methyl-2-butenyl acetate, thanks to having more sensory neurons dedicated to this smell. This ability to sense the smell more acutely is important because it directly influences where the flies lay their eggs, ensuring the survival of their offspring. Who this helps: This helps researchers and entomologists understand how specialized feeding habits shape sensory evolution in insects.

PubMed

Ralfuranone thioether production by the plant pathogen Ralstonia solanacearum.

2013

Chembiochem : a European journal of chemical biology

Pauly J, Spiteller D, Linz J, Jacobs J, Allen C +2 more

Plain English
Researchers studied how a plant pathogen called Ralstonia solanacearum produces a specific type of compound known as ralfuranones, including new forms that contain sulfur. They identified a unique process in which a sulfide from specific amino acids is transferred to these compounds, revealing details on how ralfuranone D is formed. Understanding these processes matters because it can help develop strategies to combat this pathogen that harms crops. Who this helps: This research benefits farmers and agricultural scientists looking for ways to protect plants from diseases caused by Ralstonia solanacearum.

PubMed

A conserved dedicated olfactory circuit for detecting harmful microbes in Drosophila.

2012

Cell

Stensmyr MC, Dweck HK, Farhan A, Ibba I, Strutz A +11 more

Plain English
Researchers studied how fruit flies detect harmful microbes using a specific smell, geosmin, which is released by bad yeast. They found that geosmin activates specialized nerve cells in the flies; when these cells are triggered, the flies avoid food that smells like geosmin, which helps them steer clear of toxic substances. This discovery is important because it shows how flies have developed a unique way to recognize unsafe food, which could relate to understanding similar mechanisms in other animals. Who this helps: This helps researchers studying animal behavior and safety in food sources.

PubMed

Plant species richness in montane grasslands affects the fitness of a generalist grasshopper species.

2010

Ecology

Unsicker SB, Franzke A, Specht J, Köhler G, Linz J +3 more

Plain English
This study looked at how the variety of plant species in mountain grasslands affects the life and reproductive success of a common grasshopper species called Chorthippus parallelus. Researchers found that grasshoppers laid more eggs and had more offspring in areas with greater plant diversity, with specific findings showing that sites with rich plant variety led to increased grasshopper numbers. This is important because it highlights how losing plant diversity can threaten not just specialized insects but also general ones, which can have broader impacts on ecosystems. Who this helps: This helps conservationists and environmental planners working to protect insect populations and biodiversity.

PubMed

Genetic mechanisms contributing to reduced tetracycline susceptibility of Campylobacter isolated from organic and conventional dairy farms in the midwestern and northeastern United States.

2006

Journal of food protection

Halbert LW, Kaneene JB, Linz J, Mansfield LS, Wilson D +6 more

Plain English
This study looked at how resistant Campylobacter bacteria, which can cause stomach infections, are to antibiotics on both organic and conventional dairy farms in the Midwest and Northeast U.S. The researchers tested 1,216 samples and found that a significant number of these bacteria were resistant to tetracycline, with 48% of isolates from organic farms and 58% from conventional farms showing this resistance. This is important because it highlights a common resistance to tetracycline in bacteria that can come from our food supply, raising concerns about treating infections in humans. Who this helps: This information is valuable for doctors and public health officials who are concerned about antibiotic resistance in foodborne illnesses.

PubMed

Altered sensitivity to a quaternary ammonium sanitizer in stressed Listeria innocua.

2005

Journal of food protection

Moorman M, Nettleton W, Ryser E, Linz J, Pestka J

Plain English
This study looked at how stress from heat, cold, acid, and starvation affects a type of bacteria called Listeria innocua and its resistance to a common sanitizer, cetrimide. It found that when the bacteria were stressed by acid or starvation, they became less sensitive to cetrimide, meaning they survived better; specifically, the bacteria exposed to these stressors showed decreased sensitivity compared to unstressed controls. However, heat and cold stress made the bacteria more sensitive to cetrimide, which could help sanitation efforts in food processing. Who this helps: This helps food manufacturers and safety regulators.

PubMed

Novel procedure for identification of compounds inhibitory to transcription of genes involved in mycotoxin biosynthesis.

2000

Journal of agricultural and food chemistry

Annis SL, Velasquez L, Xu H, Hammerschmidt R, Linz J +1 more

Plain English
Researchers developed a new method to find substances that block the production of harmful toxins made by certain fungi. They tested extracts from plants and discovered that a compound from black pepper, called cp2, effectively stopped the production of aflatoxin, a dangerous mycotoxin, without affecting the fungus's growth. This finding is important because it could lead to safer food by reducing mycotoxin contamination. Who this helps: This helps patients, farmers, and food producers by improving food safety.

PubMed

DNA alterations in sporadic colorectal tumors do not correlate with tumor staging diagnosed by the TNM system.

1996

Cancer letters

Deuter R, Linz J, Pietsch S, Winde G, Hentsch S +1 more

Plain English
This study looked at DNA changes in tumors from 23 patients with sporadic colorectal cancer to see if these changes related to how advanced the tumors were according to the TNM staging system. The researchers found DNA alterations in 17 tumors, but there was no link between those genetic changes and the tumor stages identified by the TNM system. This is important because it suggests that current genetic markers may not provide additional insight into tumor progression beyond what the TNM system offers. Who this helps: This helps doctors and researchers looking for better ways to understand and classify colorectal cancer.

PubMed

Molecular biology of aflatoxin biosynthesis.

1995

Microbiology (Reading, England)

Trail F, Mahanti N, Linz J

PubMed

Developmental disabilities: opportunities in LTC.

1987

Contemporary longterm care

Rose T, Linz J

PubMed

Home care audits.

1985

Caring : National Association for Home Care magazine

Linz J

PubMed

Analysis of outer membrane proteins which are associated with growth of Bacteroides thetaiotaomicron on chondroitin sulfate.

1985

Journal of bacteriology

Kotarski SF, Linz J, Braun DM, Salyers AA

Plain English
This study looked at specific proteins on the surface of a bacterium called Bacteroides thetaiotaomicron and how they help the bacterium grow on a sugar called chondroitin sulfate. Researchers found 10 proteins linked to this growth, with 4 of them being directly related to the enzymes that break down chondroitin sulfate. This finding is important because it helps us understand how certain bacteria interact with complex carbohydrates, which can impact gut health and digestion. Who this helps: This helps researchers and healthcare professionals understand gut bacteria better.

PubMed

Investigation of the relationship between adaptation measured binaurally and monaurally.

1979

British journal of audiology

Weiler EM, Linz J, Mojdehi R, Glass EB

Plain English
This study looked at how our ears adjust to sounds when tested through one ear (monaurally) compared to both ears (binaurally). Researchers found that adaptation, measured in decibels, was similar: 11.75 dB for one ear and 12.17 dB for both ears. However, they also discovered that there wasn’t a strong relationship between the two methods, indicating they might be measuring different reactions to sound. Who this helps: This information benefits audiologists and researchers focusing on hearing and sound perception.

PubMed

Frequent Co-Authors

Bill S Hansson Markus Knaden Antonia Strutz Hany K M Dweck Silke Sachse Marcus C Stensmyr F Trail Sonja Bisch-Knaden Andreas Reinecke Jakob Krieger

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.