DR. JOHN A. MECENAS, M.D.

ITHACA, NY

Research Active
Surgery NPI registered 21+ years 2 publications 2001 – 2018 NPI: 1821090036
MiceCase-Control StudiesPilot ProjectsBreast NeoplasmsMastectomyChromatography, GasBreastAntihypertensive AgentsCarotid Artery, InternalMCF-7 CellsCarotid StenosisArachidonic AcidsDelta-5 Fatty Acid DesaturaseFatty Acid DesaturasesSwiss 3T3 Cells

Practice Location

1301 TRUMANSBURG RD
ITHACA, NY 14850-1397

Phone: (607) 273-3161

What does JOHN MECENAS research?

Dr. Mecenas studies the role of specific fatty acids and surgical techniques in patient health. He has explored how a rare fatty acid called sciadonic acid is present in hormone-positive breast cancer tissue, suggesting it may influence the disease. Additionally, he has investigated the impacts of different surgical approaches to treat narrowed carotid arteries, specifically comparing the eversion technique to standard methods and assessing their effects on blood pressure post-surgery.

Key findings

  • Sciadonic acid was found in 3 out of 9 hormone-positive breast cancer samples, while absent in normal breast tissue, indicating its potential role in breast cancer biology.
  • Patients who underwent the eversion technique for carotid surgery had a 24% incidence of requiring blood pressure-lowering medications, compared to only 6% among those treated with the standard technique.

Frequently asked questions

Does Dr. Mecenas study breast cancer?
Yes, he studies the presence of fatty acids in breast cancer tissue, specifically focusing on hormone-positive cases.
What treatments has Dr. Mecenas researched?
He has researched different surgical techniques for carotid artery treatment and their effects on patients' blood pressure.
Is Dr. Mecenas's work relevant to patients with high blood pressure after surgery?
Yes, his findings highlight the importance of monitoring blood pressure in patients who undergo certain surgical techniques, like the eversion technique.

Publications in plain English

A rare eicosanoid precursor analogue, sciadonic acid (5Z,11Z,14Z-20:3), detected in vivo in hormone positive breast cancer tissue.

2018

Prostaglandins, leukotrienes, and essential fatty acids

Park HG, Zhang JY, Foster C, Sudilovsky D, Schwed DA +5 more

Plain English
This study investigated the presence of a rare fatty acid called sciadonic acid in breast cancer tissue, particularly in hormone-positive cases. Researchers found sciadonic acid in 3 out of 9 breast tumor samples but did not detect it in normal breast tissue. This discovery is important because it suggests that sciadonic acid could play a role in breast cancer biology, highlighting the need for further research on its potential effects. Who this helps: This helps researchers and doctors looking for new ways to understand and treat hormone-positive breast cancer.

PubMed

Eversion technique increases the risk for post-carotid endarterectomy hypertension.

2001

Journal of vascular surgery

Mehta M, Rahmani O, Dietzek AM, Mecenas J, Scher LA +4 more

Plain English
This study compared two surgical techniques for treating narrowed carotid arteries: the eversion technique and the standard technique. It found that patients who underwent the eversion technique experienced higher blood pressure after surgery, with 24% needing blood pressure-lowering medications compared to just 6% of those who had the standard procedure. This is important because high blood pressure after surgery can lead to complications, so doctors need to be especially careful in monitoring and treating patients who had the eversion technique. Who this helps: This helps patients undergoing carotid artery surgery and their doctors.

PubMed

Frequent Co-Authors

H G Park J Y Zhang C Foster D Sudilovsky D A Schwed S Devapatla P Lawrence K S D Kothapalli J T Brenna M Mehta

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.