Practice Location

5800 MONROE ST
SYLVANIA, OH 43560-2263

Phone: (419) 885-2525

What does JOHN STENGLE research?

Dr. Stengle studies the immune system's reactions, specifically to injuries like burns and infections such as sepsis. In one of his studies, he found that after a burn injury covering 15% of the body, there is a significant increase in immune cells called neutrophils in the lungs, indicating a robust response that occurs even when patients appear healthy. His research into sepsis highlights the risks older adults face due to their weakened immune systems and the importance of recognizing infections in this age group, as they often do not exhibit typical symptoms.

Key findings

  • After a burn injury of 15% of the body, neutrophil levels in mice increased significantly at 6 hours post-injury, returning to normal by 24 hours but rising again at 3 and 7 days.
  • Older adults with sepsis are at a higher risk for complications due to a weaker immune response, which requires prompt diagnosis and treatment to avoid severe outcomes.
  • Elderly patients may not show typical signs of infection, making early recognition critical in managing sepsis effectively.

Frequently asked questions

Does Dr. Stengle study burn injuries?
Yes, Dr. Stengle researches how the immune system responds to burn injuries, specifically focusing on neutrophils.
What conditions has Dr. Stengle researched?
He has researched sepsis, particularly in elderly patients, and how their immune systems react to infections.
Is Dr. Stengle's work relevant to elderly patients?
Yes, his research is crucial for understanding how sepsis affects older adults and highlights the need for early diagnosis and treatment.

Publications in plain English

Chest wall subcutaneous splenosis after remote trauma.

2016

Surgery

Bramos A, Stengle J

PubMed

Retropancreatic schwannoma in a young female.

2010

The American surgeon

Higgins JA, Castillo-Sang M, Godly S, Roc G, Strobel S +2 more

PubMed

Neutrophil recruitment after remote scald injury.

1996

The Journal of burn care & rehabilitation

Stengle J, Meyers R, Pyle J, Dries DJ

Plain English
This study looked at how the body responds to a burn injury and found that after a significant burn (15% of the body), there was a spike in certain immune cells called neutrophils in the lungs. Mice showed a significant increase in neutrophils at 6 hours after the injury, but this returned to normal by 24 hours, although neutrophil levels increased again after 3 and 7 days even when the mice seemed healthy. This matters because it highlights the body's ongoing immune response to burns, which can happen without obvious signs of infection. Who this helps: This research benefits doctors treating burn patients by improving their understanding of immune responses.

PubMed

Sepsis in the elderly.

1994

Critical care nursing clinics of North America

Stengle J, Dries D

Plain English
This study looked at how sepsis, a severe infection that can lead to organ failure, affects older adults. It found that older people are more at risk for complications because their immune systems are weaker and they may not show typical symptoms of infection. Quick diagnosis and immediate treatment are crucial to reduce the negative effects of these serious infections. Who this helps: This benefits elderly patients and the healthcare providers who care for them.

PubMed

Effects of chemotherapeutic agents on metabolism of human acute leukemia cells in vitro.

1958

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

LASZLO J, STENGLE J, WIGHT K, BURK D

PubMed

Certain metabolic and pharmacologic effects in cancer patients given infusions of 2-deoxy-D-glucose.

1958

Journal of the National Cancer Institute

LANDAU BR, LASZLO J, STENGLE J, BURK D

PubMed

Ultraviolet irradiation of blood in man; studies of sixty-eight patients.

1952

Journal of the American Medical Association

SCHWARTZ SO, KAPLAN SR, STENGLE J, STEVENSON FL, VINCENTI M

PubMed

The effect of antihistamine drugs upon serum-induced myocarditis in rabbits.

1947

The Journal of laboratory and clinical medicine

KYSER FA, McCARTER JC, STENGLE J

PubMed

Effect of antihistamine drugs on experimental myocarditis.

1947

The Proceedings of the Institute of Medicine of Chicago

KYSER FA, McCARTER JC, STENGLE J

PubMed

Frequent Co-Authors

J LASZLO D BURK F A KYSER J C McCARTER Athanasios Bramos Jonathan Amahl Higgins Mario Castillo-Sang Shelley Godly Gilbert Roc Stephen Strobel

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.