Comparative analysis of von Willebrand factor profiles after implantation of left ventricular assist device and total artificial heart.
2017Journal of thrombosis and haemostasis : JTH
Reich HJ, Morgan J, Arabia F, Czer L, Moriguchi J +5 more
Plain English
This study looked at how two different heart support devices—a left ventricular assist device (LVAD) and a total artificial heart (TAH)—affect a protein called von Willebrand factor (VWF), which plays a key role in blood clotting. The researchers found that all patients with TAH had a significant loss of the largest VWF molecules, while those with LVAD had varying degrees of loss, with some losing more than others. These findings are important because they show that the type of device used can lead to different bleeding risks, helping doctors better manage and treat patients who have these devices.
Who this helps: This helps patients with LVADs and TAHs by improving understanding of their bleeding risks.