Dr. Arellano studies the behavior of neutrinos, which are tiny particles that are notoriously difficult to detect. He conducts experiments using specialized detectors like MicroBooNE to measure how neutrinos interact with different materials, such as argon. His research helps to clarify fundamental questions about particle physics and tests hypotheses related to dark matter and other unexplained phenomena in the universe. Additionally, he explores cancer treatment methods, particularly using engineered gold nanorods to deliver precision therapies directly to cancer cells, aiming to overcome resistance that tumors often develop against traditional treatments.
Key findings
Measured the production rate of K+ particles from muon neutrino interactions at about 7.93 x 10^-42 cm² per nucleon, aiding future nucleon decay experiments.
Demonstrated that surface-engineered gold nanorods improve delivery of PD-L1 siRNA, leading to enhanced cancer cell death and better treatment outcomes.
Counted 4,971 instances of neutral pion production during neutrino interactions, revealing that existing models overestimate such events, especially at certain speeds.
Frequently asked questions
Does Dr. Arellano study neutrinos?
Yes, Dr. Arellano's research primarily focuses on the interactions of neutrinos, using advanced detectors to measure their behavior.
What treatments has Dr. Arellano researched for cancer?
He has developed targeted delivery methods using gold nanorods to effectively deliver cancer-fighting agents and overcome drug resistance.
Is Dr. Arellano's work relevant to patients?
Yes, his research on cancer therapies could lead to more effective treatment options for cancer patients.
What are the implications of Dr. Arellano's neutrino research?
His work helps improve our understanding of particle interactions, which is crucial for advancing theories in particle physics and potentially discovering new physics.
How does Dr. Arellano's research affect the field of particle physics?
It provides critical data that improves models of neutrino behavior and helps researchers test hypotheses related to dark matter and fundamental forces.
Publications in plain English
First Double-Differential Cross Section Measurement of Neutral-Current π^{0} Production in Neutrino-Argon Scattering in the MicroBooNE Detector.
2025
Physical review letters
Abratenko P, Alterkait O, Andrade Aldana D, Arellano L, Asaadi J +185 more
Plain English This study measured how often certain types of particles, called neutral pions (NC π^0), are produced when neutrinos collide with argon in a detector. The researchers found 4,971 cases of this event and discovered that existing models overestimate how frequently these neutral pions occur, especially when they have lower speed and scatter at certain angles. This information is important because it will help researchers predict how neutrinos behave more accurately, which is crucial for exploring potential new physics beyond what we currently understand.
Who this helps: This helps scientists and researchers studying neutrinos and their interactions.
First Measurement of ν_{e} and ν[over ¯]_{e} Charged-Current Single Charged-Pion Production Differential Cross Sections on Argon Using the MicroBooNE Detector.
2025
Physical review letters
Abratenko P, Andrade Aldana D, Arellano L, Asaadi J, Ashkenazi A +170 more
Plain English This research focused on how electron neutrinos interact with argon, specifically measuring a type of particle production called charged-pion production. The study found that the interaction rate, or cross section, is about 0.93 × 10^-39 cm² per nucleon when the neutrino energy is around 730 MeV. This information is important because it helps scientists better understand neutrino behavior, which is essential for studying both neutrino oscillations and potential new physics.
Who this helps: This benefits researchers in particle physics and helps improve neutrino experiments.
Search for an Anomalous Production of Charged-Current ν_{e} Interactions without Visible Pions across Multiple Kinematic Observables in MicroBooNE.
2025
Physical review letters
Abratenko P, Andrade Aldana D, Arellano L, Asaadi J, Ashkenazi A +174 more
Plain English This study looked at interactions of low-energy electron neutrinos at Fermilab to better understand an unexpected increase in similar events noted in a previous experiment called MiniBooNE. Researchers analyzed data from five years of the MicroBooNE experiment, showing that the new data aligns closely with expected results, but in specific areas, the predictions were higher than the actual data. Importantly, the findings ruled out a specific theory that linked the MiniBooNE excess to electron-like neutrinos with more than 99% confidence.
Who this helps: This benefits researchers studying neutrinos and potentially informs future experiments in particle physics.
Surface-engineered gold nanorods for targeted delivery of PD-L1 siRNA and cancer chemo-phototherapy.
2025
Nanoscale
Arellano L, Villar-Álvarez E, Cambón A, Costa-Santos A, Abelenda Ó +4 more
Plain English This study focused on developing a new treatment method for cancer by using specially designed gold nanorods to deliver a specific type of RNA (siRNA) that targets a protein called PD-L1, which helps tumors resist treatment. The researchers found that their gold nanorods effectively delivered the siRNA and other cancer-fighting agents to cancer cells, resulting in improved cell death and better treatment outcomes. This is important because it may help overcome the challenges of drug resistance in cancer therapies.
Who this helps: This helps cancer patients by providing a potentially more effective treatment option.
First Measurement of Charged-Current Muon-Neutrino-Induced K^{+} Production on Argon Using the MicroBooNE Detector.
2025
Physical review letters
Abratenko P, Andrade Aldana D, Arellano L, Asaadi J, Ashkenazi A +174 more
Plain English This study looked at how muon neutrinos interact with argon nuclei, specifically measuring the production of K+ particles, which are important for understanding strange particle interactions. Researchers found a specific rate for these interactions, calculated to be about 7.93 (with a margin of error) times 10^-42 cm² for each nucleon based on data from 6.88 x 10^20 protons. This finding is significant because it helps improve the accuracy of future experiments searching for nucleon decay and enhances particle detection methods.
Who this helps: This helps researchers working on neutrino experiments and particle physics.
Search for Heavy Neutral Leptons in Electron-Positron and Neutral-Pion Final States with the MicroBooNE Detector.
2024
Physical review letters
Abratenko P, Alterkait O, Andrade Aldana D, Arellano L, Asaadi J +182 more
Plain English This research focused on searching for heavy neutral leptons (HNLs) using a special detector called MicroBooNE. The study found limits on how likely these particles are to exist, showing the strongest restrictions to date for certain mass ranges, including a limit of 90% confidence for masses between 35 and 175 MeV. This matters because it helps scientists better understand the behavior of particles that may play a role in the universe's fundamental forces.
Who this helps: This helps researchers studying particle physics and the fundamental forces of nature.
First Measurement of η Meson Production in Neutrino Interactions on Argon with MicroBooNE.
2024
Physical review letters
Abratenko P, Alterkait O, Andrade Aldana D, Anthony J, Arellano L +183 more
Plain English This study looked at how neutrinos interact with argon by measuring a specific particle called the η meson. Researchers found that the rate of η meson production from these interactions is 3.22, with some uncertainty in the measurements. This is important because it provides a new way to understand these interactions, which can improve future experiments on how neutrinos behave.
Who this helps: This benefits scientists and researchers working in neutrino physics.
Assessing the Effect of Surface Coating on the Stability, Degradation, Toxicity and Cell Endocytosis/Exocytosis of Upconverting Nanoparticles.
2024
Journal of colloid and interface science
Arellano L, Martínez R, Pardo A, Diez I, Velasco B +4 more
Plain English This study looked at how different surface coatings on upconverting nanoparticles (UCNPs), which are tiny particles with potential uses in medicine, affect their stability, breakdown, toxicity, and interaction with cells. Researchers found that one type of coating, called PMA-g-dodecyl, keeps the nanoparticles stable and less toxic, while another common coating, PEG, actually prevents effective cell uptake. This research is important because it helps scientists design better nanoparticles for medical applications, enhancing their effectiveness as tools for diagnosis and treatment.
Who this helps: Patients and doctors looking for improved medical technologies.
Neural Signatures of Evidence Accumulation Encode Subjective Perceptual Confidence Independent of Performance.
2024
Psychological science
Dou W, Martinez Arango LJ, Castaneda OG, Arellano L, Mcintyre E +2 more
Plain English This research studied how the brain processes and measures a person's confidence in their decisions, regardless of how well they perform on a task. The scientists found that a specific brain signal called the central-parietal positive component (CPP) predicts a person's confidence level even when taking into account their accuracy and how quickly they respond. Specifically, this signal remained a strong predictor of confidence across three different experiments with 24 to 25 adults involved.
Who this helps: This helps patients and individuals making decisions, especially in uncertain situations.
First Search for Dark-Trident Processes Using the MicroBooNE Detector.
2024
Physical review letters
Abratenko P, Alterkait O, Andrade Aldana D, Arellano L, Asaadi J +182 more
Plain English This study looked for evidence of dark matter particles using a special detector called MicroBooNE at Fermilab. They analyzed data from 7.2 billion proton collisions and found no direct signals of dark matter interactions, but established new limits on how dark matter might behave, specifically regarding its interaction with a hypothetical particle called a dark photon. These findings help scientists narrow down the possibilities for dark matter, making it easier to identify its properties in future experiments.
Who this helps: This helps researchers studying dark matter and its fundamental properties.
First Simultaneous Measurement of Differential Muon-Neutrino Charged-Current Cross Sections on Argon for Final States with and without Protons Using MicroBooNE Data.
2024
Physical review letters
Abratenko P, Alterkait O, Andrade Aldana D, Arellano L, Asaadi J +182 more
Plain English This research focused on measuring how muon neutrinos interact with argon, specifically looking at events that produce protons and those that do not. The scientists found that existing models used to predict these interactions do not accurately represent events without protons, indicating serious gaps in our understanding of how these interactions work. This is important because it can improve how we analyze and interpret future neutrino experiments, leading to better detection and understanding of these fundamental particles.
Who this helps: This benefits researchers and scientists working in particle physics and neutrino experiments.
Duration of Cattle Ranching Affects Dung Beetle Diversity and Secondary Seed Removal in Tropical Dry Forest Landscapes.
2024
Insects
Morales-Trejo JJ, Dáttilo W, Zurita G, Arellano L
Plain English This study looked at how long cattle ranching has been practiced in tropical dry forests in Mexico and its impact on dung beetle diversity and seed removal. It found that while the overall number of beetle species remained similar over time, there was a decrease in the variety of common and dominant native species and an increase in exotic species. This matters because dung beetles play a crucial role in the ecosystem by helping with seed removal, and changes in their community can lead to negative effects on the forest environment.
Who this helps: This benefits conservationists and environmental scientists who are working to protect ecosystems.
First Constraints on Light Sterile Neutrino Oscillations from Combined Appearance and Disappearance Searches with the MicroBooNE Detector.
2023
Physical review letters
Abratenko P, Andrade Aldana D, Anthony J, Arellano L, Asaadi J +181 more
Plain English This study looked for light sterile neutrinos using the MicroBooNE detector, which is designed to detect neutrinos from Fermilab's booster beam. After analyzing data from over 6 trillion protons, researchers found no signs of these neutrinos oscillating, setting strong limits on their existence within certain mass and mixing ranges. This matters because it helps refine our understanding of neutrinos, which are important for grasping fundamental physics and the universe.
Who this helps: This helps researchers and scientists studying particle physics and the fundamental forces of nature.
First Measurement of Quasielastic Λ Baryon Production in Muon Antineutrino Interactions in the MicroBooNE Detector.
2023
Physical review letters
Abratenko P, Andrade Aldana D, Anthony J, Arellano L, Asaadi J +180 more
Plain English This study measured how often a specific type of particle, called a Lambda baryon, is produced when muon antineutrinos interact with argon in a detector at Fermilab. The researchers analyzed data from two experiments, finding around five events where these baryons were detected, which aligns closely with a prediction of about 5.3 events. Understanding this production helps scientists learn more about neutrinos and their interactions, which could advance particle physics and improve our knowledge of the universe.
Who this helps: This helps researchers and physicists studying particle interactions and the fundamental forces of nature.
First Double-Differential Measurement of Kinematic Imbalance in Neutrino Interactions with the MicroBooNE Detector.
2023
Physical review letters
Abratenko P, Alterkait O, Andrade Aldana D, Anthony J, Arellano L +181 more
Plain English This study looked at how neutrinos (tiny particles that are difficult to detect) interact with argon using a special detector called MicroBooNE. Researchers discovered important details about these interactions, finding that specific measurements (called cross sections) revealed different effects of nuclear structures on how neutrinos behave with argon. This is crucial because it enhances our understanding of neutrino behavior and helps improve models used in other neutrino research.
Who this helps: This benefits scientists studying neutrinos and their interactions, which could lead to advancements in particle physics and related fields.
Dung removal increases under higher dung beetle functional diversity regardless of grazing intensification.
2023
Nature communications
Noriega JA, Hortal J, deCastro-Arrazola I, Alves-Martins F, Ortega JCG +62 more
Plain English This study looked at how different types of dung beetles help remove animal waste in pastures, particularly when farming practices get more intense. The researchers found that having a greater variety of dung beetles leads to better dung removal, with increases in species richness resulting in improved waste management. For example, in pastures with more diverse beetle populations, dung removal rates were consistently better, regardless of how intensely the land was grazed. This research is important because it shows that healthy beetle communities can support soil health and nutrient recycling even in more heavily farmed areas.
Who this helps: Farmers and land managers seeking to maintain healthy soil and ecosystem services.
Combined Therapeutics for Atherosclerosis Treatment Using Polymeric Nanovectors.
2022
Pharmaceutics
Leal BH, Velasco B, Cambón A, Pardo A, Fernandez-Vega J +7 more
Plain English This study looked at a new way to treat atherosclerosis, a condition that can lead to heart diseases, by using tiny particles to deliver both a drug and a molecule that helps regulate genes. Researchers created nanoparticles that can carry the drug atorvastatin and a specific microRNA, which together significantly lowered harmful substances in cells linked to inflammation, reducing levels of certain inflammatory proteins by up to 70%. This approach could lead to more effective treatments for atherosclerosis without the side effects of current medications.
Who this helps: This benefits patients with atherosclerosis and cardiovascular diseases.
Provider Perspectives on and Access to Palliative Care for Patients With Interstitial Lung Disease.
2022
Chest
Gersten RA, Seth B, Arellano L, Shore J, O'Hare L +8 more
Plain English This study looked at how doctors who treat patients with interstitial lung disease (ILD) view and access palliative care, which focuses on improving the quality of life for seriously ill patients. Among the 128 participating healthcare providers, most understood the importance of palliative care but tended to refer patients only when the disease worsened, rather than at the initial diagnosis. Key barriers to providing better palliative care included a lack of local services and standardized tools to assess patients' symptoms.
Who this helps: This benefits patients with ILD who need better support for managing their symptoms and improving their quality of life.
Search for Neutrino-Induced Neutral-Current Δ Radiative Decay in MicroBooNE and a First Test of the MiniBooNE Low Energy Excess under a Single-Photon Hypothesis.
2022
Physical review letters
Abratenko P, An R, Anthony J, Arellano L, Asaadi J +184 more
Plain English This study explored how neutrinos can produce certain particles, called Δ baryons, and how these particles decay, using a neutrino beam at the MicroBooNE experiment. Researchers recorded events during three years of operation, finding 16 cases of one photon plus one proton and 153 cases of one photon with no protons. These results showed that the process occurs less frequently than previously thought, making it less likely that a type of photon could explain some unexpected findings from another experiment called MiniBooNE.
Who this helps: This benefits researchers studying neutrinos and particle physics, as well as contributing to our understanding of fundamental particles and forces.
First Measurement of Energy-Dependent Inclusive Muon Neutrino Charged-Current Cross Sections on Argon with the MicroBooNE Detector.
2022
Physical review letters
Abratenko P, An R, Anthony J, Arellano L, Asaadi J +181 more
Plain English This research measured how muon neutrinos interact with argon, focusing on how often these interactions occur and how they depend on the energy of the neutrinos. The team collected data from 5.3 billion protons hitting a target, providing the first detailed look at the relationship between the energy of the neutrinos and the energy they transferred in their interactions. These findings are important because they help improve our understanding of neutrino behavior, which is essential for experiments in particle physics.
Who this helps: This helps scientists and researchers studying fundamental particles and their interactions.
Search for an Excess of Electron Neutrino Interactions in MicroBooNE Using Multiple Final-State Topologies.
2022
Physical review letters
Abratenko P, An R, Anthony J, Arellano L, Asaadi J +190 more
Plain English In this study, researchers measured interactions of electron neutrinos using a special detector at Fermilab to investigate a previous unexpected increase in low-energy interactions. They conducted three different types of searches, but ultimately found no significant excess of electron neutrino events—meaning their results aligned closely with expected rates, indicating everything is generally as expected rather than having any surprising increases. This is important because understanding neutrino interactions helps scientists learn more about fundamental particles and the universe.
Who this helps: This helps physicists and researchers studying particle physics and the nature of the universe.
Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.
2022
The European physical journal. C, Particles and fields
Abud AA, Abi B, Acciarri R, Acero MA, Adames MR +1222 more
Plain English This study examined how light generated by charged particles in a large liquid argon detector, called ProtoDUNE, was detected and measured. Researchers found that the system effectively captured light signals from cosmic muons even when the sources were up to 7 meters away. Understanding these light signals is crucial, as they enhance the accuracy of measurements in future neutrino research projects.
Who this helps: This benefits scientists and researchers working on neutrino physics and related experiments.
Recall of government healthy eating campaigns by consumers in five countries.
2021
Public health nutrition
Goodman S, Armendariz GC, Corkum A, Arellano L, Jáuregui A +7 more
Plain English This study looked at how well people in five countries (Australia, Canada, Mexico, the UK, and the USA) remembered government campaigns about healthy eating from the past year. The findings showed that awareness was highest in Mexico at 50.9%, compared to much lower percentages in the UK (18.2%), Australia (17.9%), the USA (13.0%), and Canada (10.2%). Overall, men and those with higher education levels were more likely to recall these campaigns, and common themes included sugar, fruits and vegetables, and physical activity.
Who this helps: This benefits public health officials and organizations trying to promote better eating habits in the population.
Atmospheric deposition of semivolatile organic pollutants in European high mountains: Sources, settling and chemical degradation.
2021
The Science of the total environment
Fernandez P, van Drooge BL, Arellano L, Grimalt JO
Plain English This study looked at how various harmful chemicals from the air, including pollutants like PCBs and PAHs, settle in four high mountain lakes in Europe over a period from 2004 to 2006. Researchers found that wet deposition (rain and snow) was the main way these pollutants were removed from the atmosphere, with some lakes experiencing higher levels of specific pollutants from local sources rather than long-range transport. For example, the lake Skalnate in Slovakia received more PAHs and endosulfans from nearby areas, while the lakes in the Alps and Pyrenees were influenced by long-distance pollution.
Who this helps: This research benefits environmental scientists and policymakers working to protect mountain ecosystems and public health.
Assembly mechanisms of dung beetles in temperate forests and grazing pastures.
2020
Scientific reports
Ortega-Martínez IJ, Moreno CE, Rios-Díaz CL, Arellano L, Rosas F +1 more
Plain English This research looked at how dung beetles form their communities in forests and managed grasslands to see what factors affect their diversity. The study found that chance plays a larger role than environmental factors in shaping beetle populations, meaning that the way these beetles come together is more random than based on specific conditions. This is important because it shows that improving connections between habitats might be more beneficial for preserving diverse beetle species than trying to enhance individual habitats.
Who this helps: This helps conservationists and land managers working to protect biodiversity.
Combination of light-driven co-delivery of chemodrugs and plasmonic-induced heat for cancer therapeutics using hybrid protein nanocapsules.
2019
Journal of nanobiotechnology
Villar-Alvarez E, Cambón A, Pardo A, Arellano L, Marcos AV +8 more
Plain English This study looked at a new way to deliver cancer-fighting drugs using tiny carriers made from a combination of human proteins and chitosan, a natural substance. The researchers found that when these carriers combined two drugs—docetaxel and doxorubicin—and were activated by infrared light, they significantly increased the killing effect on cancer cells, achieving nearly 90% cell death with just a single dose of light treatment. This method is important because it could lead to more effective and targeted cancer therapies, particularly for hard-to-treat types like metastatic breast cancer.
Who this helps: This helps cancer patients, particularly those with triple-negative breast cancer.
Assessing Three Sampling Methods to Survey and Monitor Ground Beetles (Coleoptera: Carabidae) in Riparian Cloud Forests.
2018
Environmental entomology
Ramírez-Hernández A, Escobar F, Montes de Oca E, Arellano L
Plain English This study examined three different methods for collecting ground beetles in cloud forests to see which was the most effective for monitoring biodiversity. The researchers found that hand collection and light trapping were the best methods, with hand collection yielding the most beetles and light trapping capturing the largest variety of species. However, pitfall trapping was not effective in these diverse environments. This research is important because it helps establish better ways to survey beetle populations, aiding conservation efforts in these vulnerable ecosystems.
Who this helps: This benefits conservationists and scientists working to protect cloud forest ecosystems.
Persistent organic pollutant accumulation in seasonal snow along an altitudinal gradient in the Tyrolean Alps.
2014
Environmental science and pollution research international
Arellano L, Grimalt JO, Fernández P, Lopez JF, Nickus U +1 more
Plain English This study looked at how much pollution accumulates in seasonal snow on the Tyrolean Alps, focusing on different pollutants like polycyclic aromatic hydrocarbons (PAHs) and various brominated and chlorinated compounds. The researchers found that PAHs had the highest concentrations in the snow, ranging from 500 to 8,400 picograms per liter, while polychlorinated biphenyls (PCBs) and polybromodiphenyl ethers (PBDEs) were found in lower amounts. Understanding the levels of these pollutants is important because they can be harmful to the environment and human health, showing how pollution can travel and affect remote areas.
Who this helps: This helps environmental scientists and public health officials track pollution levels and assess risks.
Basaloid carcinoma of the prostate: an extremely rare tumor.
2013
Archivos espanoles de urologia
Rodriguez-Carlin A, Arellano L, López-Fontana G, Bolufer E, Castillo OA
Plain English This study looked at a very rare type of prostate cancer called basaloid carcinoma, which affects the prostate's basal cells. Researchers reported on a 76-year-old man's case, showing he had significant urinary problems and low PSA levels before treatment. After surgeries in 2008 and 2009, follow-ups revealed he had no signs of cancer recurrence and maintained full bladder control for 23 months.
Who this helps: This information benefits doctors and patients dealing with rare prostate cancer types.
[Renal cell carcinoma of the collecting ducts of bellini with retroperitoneal recurrence by another histological subtype Of renal tumor].
2013
Archivos espanoles de urologia
Rodriguez Carlin A, Vidal Mora I, Arellano L, Castillo OA
Plain English This study discusses a rare and aggressive type of kidney cancer called collecting duct carcinoma (CDC) in a 59-year-old man who initially had surgery for a tumor in his kidney. Ten months after the surgery, scans revealed that the cancer had returned in the area around the kidney, leading to a second operation to remove the new tumor, which turned out to be a different type of kidney cancer. This research is important because it highlights the aggressive nature of CDC and the possibility of it returning as a different cancer, which can significantly impact treatment decisions.
Who this helps: This helps doctors and patients dealing with rare kidney cancers by providing insights into potential complications and treatment options.
[Quality of DNA from archival pathological samples of gallbladder cancer].
2013
Revista medica de Chile
Roa I, de Toro G, Sánchez T, Slater J, Ziegler AM +4 more
Plain English This study examined the quality of DNA from gallbladder cancer samples stored in hospitals in Chile to see how suitable they are for research. Out of 194 samples tested, the average DNA concentration was about 48 nanograms per microliter, but 22% of the samples did not yield usable DNA for analysis. The results showed that while most samples had sufficient DNA integrity for research, those from public hospitals were generally of lower quality compared to those from private clinics.
Who this helps: This benefits researchers who study gallbladder cancer by providing insights into DNA quality for future studies.
Implant-guided volumetric analysis of edentulous maxillary bone with cone-beam computerized tomography scan. Maxillary sinus pneumatization classification.
2012
The Journal of oral implantology
Tolstunov L, Thai D, Arellano L
Plain English This study examined the amount of bone available in the upper jaw of patients who have lost their teeth, using a special type of 3D imaging called a cone-beam CT scan. It found that, on average, there is 4,408.1 cubic millimeters of bone that can support dental implants without needing extra procedures like bone grafts, with most patients having enough good quality bone for treatment. This is important because it suggests that many patients can receive full sets of dental implants more easily and affordably.
Who this helps: This benefits patients needing dental implants, especially older adults.
[Human intestinal spirochetosis: clinical series and literature review].
2012
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
Lozano C, Arellano L, Yaquich P
Plain English This study looked at a condition called human intestinal spirochetosis (HIE), which is linked to long-lasting diarrhea. Researchers examined 115 patients at a hospital in Salvador, and found that 1.7% of those tested had HIE, specifically two cases in patients without HIV. This information is important because it helps understand the presence of this condition in different populations, guiding future research and treatment options.
Who this helps: This helps patients suffering from chronic diarrhea and their doctors.
[Partial laparoscopic adrenalectomy in primary hyperaldosteronism].
2011
Actas urologicas espanolas
Castillo OA, Díaz M, Arellano L
Plain English This study looked at a surgical treatment called partial laparoscopic adrenalectomy for patients with primary hyperaldosteronism, a condition that can cause high blood pressure. The researchers operated on 16 patients and found that all of them improved their blood pressure after the surgery, which took an average of about 71 minutes and had minimal bleeding (about 30 ml). This is important because it shows that a less invasive surgery can be effective for curing a condition that leads to high blood pressure, helping patients avoid more complications from traditional open surgery.
Who this helps: This helps patients with primary hyperaldosteronism and hypertension.
Long-range transported atmospheric pollutants in snowpacks accumulated at different altitudes in the Tatra Mountains (Slovakia).
2011
Environmental science & technology
Arellano L, Fernández P, Tatosova J, Stuchlik E, Grimalt JO
Plain English This study examined snow samples from different heights in the Tatra Mountains to see how much harmful atmospheric pollutants were present. The researchers found various pollutants in all samples, with polycyclic aromatic hydrocarbons (PAHs) being the most common, showing average levels between 90 and 300 nanograms per liter. They discovered that the concentration of these pollutants generally increased with altitude, indicating that colder temperatures in higher areas trap these pollutants, which is significant for understanding pollution in remote environments.
Who this helps: This information aids environmental scientists and policymakers in addressing air quality and pollution control efforts in mountainous regions.
Diversifying Science: Underrepresented Student Experiences in Structured Research Programs.
2009
Research in higher education
Hurtado S, Cabrera NL, Lin MH, Arellano L, Espinosa LL
Plain English The study looked at how underrepresented undergraduate students experience structured science research programs at four different institutions. Researchers found that while students felt confident in their science abilities and developed clear career goals, they also faced challenges related to race and social stigma within the scientific community. These insights highlight the importance of fostering an inclusive environment in science to better support all aspiring researchers.
Who this helps: This benefits underrepresented students in science and the institutions that support them.
Analysis of whole congener mixtures of polybromodiphenyl ethers by gas chromatography-mass spectrometry in both environmental and biological samples at femtogram levels.
2009
Journal of chromatography. A
Vizcaino E, Arellano L, Fernandez P, Grimalt JO
Plain English This study focused on developing a highly sensitive method to measure certain harmful chemicals, known as polybromodiphenyl ethers, in both environmental samples (like snow) and biological samples (like human tissue). The researchers found they could reliably detect these chemicals at very low levels, down to less than 15 parts per trillion, showing good consistency in their results. This is important because it helps us understand the presence and impact of these harmful substances in the environment and human health.
Who this helps: This helps patients and environmental health researchers.
Laparoscopic adrenalectomy for adrenal masses: does size matter?
2008
Urology
Castillo OA, Vitagliano G, Secin FP, Kerkebe M, Arellano L
Plain English This study looked at how the size of adrenal tumors affects the safety and recovery of patients undergoing laparoscopic adrenal surgery. Researchers analyzed 227 patients and found that those with larger tumors (8 cm or more) took longer to operate on (80 minutes on average), lost more blood (100 mL), and had longer hospital stays (3 days) compared to patients with smaller tumors (less than 6 cm) who had a shorter average surgery time (60 minutes, 50 mL of blood loss, and 2 days in the hospital). Understanding these differences helps doctors plan better for surgeries and manage patient care more effectively, especially for those with larger tumors.
Who this helps: This helps patients undergoing adrenal tumor surgery and their doctors.
Analysis of polybrominated diphenyl ethers in atmospheric deposition and snow samples by solid-phase disk extraction.
2008
Journal of chromatography. A
Quiroz R, Arellano L, Grimalt JO, Fernández P
Plain English This study focused on analyzing a group of chemicals known as polybrominated diphenyl ethers (PBDEs) in water and snow samples. The researchers developed a method that successfully achieved a 97% efficiency in extracting these chemicals, with higher recovery rates for the more volatile PBDEs. This is important because it allows for precise measurement of PBDE levels in remote areas of Europe, where pollution levels can be low to medium.
Who this helps: This helps environmental scientists and policymakers monitor chemical pollution in remote ecosystems.
Laparoscopic adrenalectomy for adrenal myelolipoma.
2007
Archivos espanoles de urologia
Castillo OA, Vitagliano G, Cortes O, Sánchez-Salas R, Arellano L
Plain English This study looked at the results of a minimally invasive surgery called laparoscopic adrenalectomy for removing adrenal myelolipomas, which are rare benign tumors of the adrenal gland. Out of 226 surgeries performed at the hospital, 19 involved these tumors, with an average tumor size of 8.6 cm. The surgery had a mean duration of about 85 minutes, minimal blood loss, and patients typically stayed in the hospital for just over 2 days, with no serious complications.
Who this helps: This benefits patients with adrenal myelolipoma, providing them with an effective and safe surgical option.
[Single-stage laparoscopic adrenalectomy and pancreatic cyst exsicion in a patient with von Hippel-Lindau disease].
2007
Actas urologicas espanolas
Castillo O, Kerkebe M, Vitagliano G, Arellano L
Plain English This study examined a 20-year-old man with von Hippel-Lindau disease, who underwent a single surgical procedure to remove two growths: a 5 cm tumor on his adrenal gland and a 3 cm cyst from his pancreas. The surgery lasted 120 minutes, involved minimal bleeding (less than 50 mL), and he stayed in the hospital for just three days with no complications. This approach is important because it shows that complex surgeries can be safely performed at the same time, which can potentially improve outcomes for patients with similar conditions.
Who this helps: Patients with von Hippel-Lindau disease facing multiple tumors or cysts.
Castillo OA, Vitagliano G, Cortes O, Kerkebe M, Pinto I +1 more
Plain English This study focused on a type of surgery called bilateral laparoscopic adrenalectomy, which is used to remove both adrenal glands when other treatments have failed. Researchers looked at 44 cases over six years, finding the surgery was mostly successful: patients had an average recovery time of just over three days and very little bleeding, with only one complication occurring in the entire group. These findings show that this surgery is effective and safe, allowing doctors to treat adrenal issues more efficiently.
Who this helps: This helps patients with adrenal tumors or hormonal disorders.
Instability of copronecrophagous beetle assemblages (Coleoptera: Scarabaeinae) in a mountainous tropical landscape of Mexico.
2007
Environmental entomology
Halffter G, Pineda E, Arellano L, Escobar F
Plain English This study looked at how the types and abundance of certain beetles, which help in breaking down animal waste, change over time in different environments in a mountainous region of Mexico. Researchers found that while the overall richness of beetle species stayed somewhat stable across the landscape, the specific local diversity changed significantly, especially in places like cloud forests and pastures, suggesting these areas are sensitive to human activities. This matters because it highlights how even small changes in the environment can significantly impact local ecosystems and helps us understand the effects of human activity on biodiversity.
Who this helps: This helps environmental scientists and conservationists working to protect ecosystems.
Thermoregulation in endothermic dung beetles (Coleoptera: Scarabaeidae): effect of body size and ecophysiological constraints in flight.
2006
Journal of insect physiology
Verdú JR, Arellano L, Numa C
Plain English Researchers studied how body size affects temperature control during flight in a type of dung beetle. They found that larger dung beetles (weighing more than 1.9 grams) can keep their body temperature much warmer than the surrounding air, while smaller beetles do not. The maximum temperature they can handle while flying is 42 degrees Celsius, and they need it to be at least 25 degrees Celsius to fly, which may influence where these beetles are found in nature.
Who this helps: This helps scientists and conservationists understand how climate affects different sizes of beetles.
Plain English This study looked at 16 patients with inverted papilloma of the bladder, a rare type of growth. Most patients (44%) sought help because they urgently needed to urinate, and 38% had blood in their urine. Surgery was performed on all patients, and about 13% had another type of bladder cancer alongside the inverted papilloma, making it important to monitor for possible cancer growth in these cases.
Who this helps: This research benefits doctors and patients dealing with bladder issues.
[Laparoscopic surgery in the treatment of adrenal pathology: experience with 200 cases].
2006
Actas urologicas espanolas
Castillo O, Cortés O, Kerkebe M, Pinto I, Arellano L +1 more
Plain English This study looked at 200 cases of laparoscopic surgery on adrenal glands over a ten-year period, focusing on patients with various adrenal gland issues. The researchers found that most patients were women around 49 years old and reported a 6% complication rate, with an average surgery lasting about 83 minutes and hospital stays averaging 2.5 days. These findings show that laparoscopic surgery is a safe and effective option for treating adrenal problems, helping patients recover more quickly with less risk than traditional surgery.
Who this helps: This benefits patients needing adrenal surgery and their doctors.
[Inflammatory reconstitution immune syndrome associated to antiretroviral therapy and meningeal cryptococcosis].
2006
Revista medica de Chile
Sáez D, Bahamondes L, Lam G, Arellano L, Lillo P
Plain English This study looked at a 37-year-old woman with AIDS who had previously been treated for meningitis caused by a fungal infection. After starting a strong antiviral treatment, she experienced a sudden worsening of her symptoms eight months later, specifically developing aseptic meningitis and increased pressure in her brain, even though tests couldn't identify an active infection. This situation is known as Inflammatory Reconstitution Immune Syndrome (IRIS), which can happen when the immune system starts to recover and mistakenly reacts to past infections.
Who this helps: This information benefits patients with AIDS and their doctors by highlighting potential complications during treatment.
JSLS : Journal of the Society of Laparoendoscopic Surgeons
Castillo OA, Vitagliano G, Villeta M, Arellano L, Santis O
Plain English This study looked at two patients, ages 8 and 61, who had rare tumors called adrenal teratomas, which are found in the adrenal gland. The tumors were successfully removed using a minimally invasive surgical technique called laparoscopic surgery. Both patients were found to be cancer-free after the procedure, with one recovering in just two days and the other taking ten days due to some complications.
Who this helps: This benefits patients with adrenal teratomas and doctors performing similar surgeries.