LEAH WINER, M.D.

LEXINGTON, KY

Research Active
Surgery - Surgical Oncology NPI registered 11+ years 47 publications 2016 – 2026 NPI: 1124415922

Practice Location

800 ROSE ST WHITNEY HENDRICKSON BLDG STE 134
LEXINGTON, KY 40536-0558

Phone: (859) 323-6346

What does LEAH WINER research?

Dr. Winer studies the surgical education and training of general surgery residents, especially those who aspire to become surgical oncologists or breast surgeons. Her research investigates how different factors, such as gender and program type, affect residents' surgical experiences and the number of operations they perform during their training. She also explores how the surgical residency structure can be improved to better prepare graduates for their future careers, taking into account the impact of events like the COVID-19 pandemic on surgical opportunities.

Key findings

  • Residents pursuing breast surgical oncology fellowships performed 50% more breast operations than their peers but logged fewer cases in other surgical areas.
  • Female general surgery residents performed significantly fewer total surgeries than males, with female residents being 26% less likely to be categorized as high-volume residents.
  • The COVID-19 pandemic resulted in a 1.5% overall decrease and an 8% decrease in chief-level operative cases for residents who graduated in 2020 compared to those in 2019.
  • Characteristics like being female and training at low-volume programs were linked to decreased operational experience, creating disparities that can be targeted for intervention.
  • 88% of residency applicants felt more positively about programs after virtual interviews during the pandemic, with many supporting a hybrid interview model moving forward.

Frequently asked questions

Does Dr. Winer study disparities in surgical training?
Yes, Dr. Winer's research specifically examines disparities in operative experiences among surgery residents, particularly focusing on gender-related differences.
What conditions does Dr. Winer focus on in her research?
Dr. Winer focuses on surgical oncology and breast surgery, analyzing how residency training impacts future surgeons in these specialties.
How has COVID-19 affected surgical training according to Dr. Winer's research?
Her research shows that the COVID-19 pandemic led to significant reductions in surgery case volumes for residents, which could impact their training quality and competence.
What improvements does Dr. Winer suggest for surgical residency programs?
Dr. Winer advocates for restructuring residency programs based on her findings, particularly to address disparities and enhance hands-on surgical training opportunities.
Is Dr. Winer's work relevant to future surgical residents?
Absolutely, Dr. Winer's research provides insights that can help shape how residency programs are designed, improving training experiences for upcoming surgeons.

Publications in plain English

Making the House a Home: Cultivating Community in Surgery.

2026

Annals of surgery

Eruchalu CN, Cortez AR, Winer LK, Cho NL

PubMed

Defining the Surgical Oncology Experience during General Surgery Residency: A Multi-Institutional Study from the US ROPE Consortium.

2026

Annals of surgical oncology

Reagan AM, Montgomery KB, Woeste MR, Sutton JM, Smith SR +28 more

Plain English
Researchers analyzed case logs from 1,343 general surgery graduates across 20 programs to characterize the training experience of those who pursued a surgical oncology fellowship. Future oncology fellows performed more cancer-relevant operations — particularly liver, pancreas, and endocrine cases — and were more likely to train at university-based programs with dedicated oncology faculty and NCI cancer centers. Dedicated research time and institutional NIH funding were the strongest independent predictors of pursuing this fellowship path.

PubMed

ASO Visual Abstract: Defining the Surgical Oncology Experience During General Surgery Residency: A Multi-Institutional Study from the US ROPE Consortium.

2026

Annals of surgical oncology

Reagan AM, Montgomery KB, Woeste MR, Sutton JM, Smith SR +28 more

PubMed

Current patterns of care and outcomes for dermatofibrosarcoma protuberans: An international multi-institutional collaborative.

2025

Cancer

Winer LK, Akumuo R, Fredette JD, Deng M, Hasler JS +18 more

Plain English
This study looked at how dermatofibrosarcoma protuberans (DFSP), a type of skin cancer, is treated across different countries and what the outcomes are for patients. Researchers analyzed data from 347 DFSP patients and found that 89.5% were eventually able to have their tumors removed with no cancer left behind (R0 resection), but one in five patients needed additional surgery to achieve this. Importantly, the survival rate for these patients was very high at 98.8% over a median follow-up of nearly four years, showing that with proper treatment, the outlook for DFSP patients is optimistic. Who this helps: This information benefits patients with DFSP and their doctors by providing insights into effective treatment strategies.

PubMed

ASO Author Reflections: Beyond the Binary: Using IHC Status to Predict Response to Neoadjuvant Therapy in HER2+ Early-Stage Breast Cancer.

2025

Annals of surgical oncology

Winer LK, Williams AD

PubMed

Examining the Impact of Biopsy Technique on Clinical and Pathologic Outcomes in Dermatofibrosarcoma Protuberans: An International, Multi-Institutional Study.

2025

Annals of surgical oncology

Winer LK, Fredette JD, Hasler J, Akumuo R, Greco SH +17 more

Plain English
This study looked at how different biopsy techniques for a rare skin cancer called dermatofibrosarcoma protuberans (DFSP) affect patient outcomes. Researchers analyzed data from 321 patients and found that those who had a preoperative biopsy had better results: 78.6% achieved a successful removal with clean margins compared to 60.1% of those who had an excisional biopsy, and fewer complications occurred with preoperative biopsy (25.6% versus 38.2%). These findings matter because they suggest that preoperative biopsies may lead to easier and safer surgeries for patients. Who this helps: This helps patients diagnosed with dermatofibrosarcoma protuberans and their doctors.

PubMed

ASO Author Reflections: Removing the Element of Surprise: Reducing Unplanned Excisions to Enhance Dermatofibrosarcoma Protuberans Outcomes.

2025

Annals of surgical oncology

Winer LK, Farma JM, Villano AM

PubMed

ASO Author Reflections: General Surgery Training for Future Breast Surgeons Reflects Early Specialization.

2025

Annals of surgical oncology

Reagan AM, Winer LK

PubMed

Characterizing the General Surgery Experience of Future Breast Surgeons: A Multi-institutional Study from the US ROPE Consortium.

2025

Annals of surgical oncology

Reagan AM, Jones VM, Ibrahim-Zada I, Smith SR, Postlewait LM +30 more

Plain English
A multi-institutional analysis of surgical training logs found that residents who went on to pursue breast surgical oncology fellowships performed 50% more breast operations during residency than their peers, despite having similar access to breast surgery rotations. However, these same residents logged fewer total cases across most other surgical domains. The pattern suggests future breast surgeons self-select toward breast cases early in training, with implications for how residency programs should be structured.

PubMed

Resident perspectives on the role of gender in operative experience during general surgery residency training: A mixed-methods study.

2024

American journal of surgery

Winer LK, Panzica N, Lynch K, Parker C, Lancaster R +6 more

Plain English
This study looked into why female residents in general surgery get less hands-on experience in the operating room compared to their male counterparts. Researchers found that 22% of women reported facing obstacles that hindered their ability to participate in surgeries, and more than half felt that their gender affected their training opportunities. The findings highlight that sexism and bias are significant barriers, and the residents suggested creating clearer guidelines and feedback systems to ensure fair access to surgical cases. Who this helps: This research benefits female surgery residents and helps ensure fair training opportunities for all genders.

PubMed

Defining the Disparity: A Multi-Institutional Analysis of Factors Associated With Decreased Resident Operative Experience.

2024

The Journal of surgical research

Price AD, Foote DC, Woeste MR, Winer LK, Montgomery KB +7 more

Plain English
A post-hoc analysis of training logs from 1,343 general surgery residents identified characteristics associated with landing in the bottom quartile for total operative volume. Low-volume residents were more likely to be female, underrepresented in medicine, and training at low-volume or highly NIH-funded programs. The findings highlight that disparities in operative experience are shaped by both individual and institutional factors that can be targeted for intervention.

PubMed

Are General Surgery Residencies Preparing Graduates for the Practice of Today's General Surgeon? An Analysis of American Board of Surgery Data From Applicants and Re-certifying Surgeons.

2023

Annals of surgery

Cortez AR, Ibáñez B, Winer LK, Jones AT, Quillin RC +2 more

Plain English
A comparison of operative case logs from 5,482 general surgery graduates and 4,152 practicing surgeons found that resident training closely mirrors real-world practice in core domains like abdominal and alimentary tract surgery. Residents get more experience in subspecialty areas like trauma and vascular surgery due to their training environment, while practicing surgeons do more breast work. The data provide reassurance that surgical training is appropriately aligned with the operations graduates will encounter in practice.

PubMed

General Surgery Residency Virtual Recruitment During the Pandemic: An Analysis of Applicant Surveys.

2023

The Journal of surgical research

Vaysburg DM, Delman AM, Ammann AM, Turner KM, Winer LK +5 more

Plain English
A survey of 60 residency applicants who interviewed virtually during the 2020-2022 cycles found that 88% came away with a more favorable view of the program after a virtual interview, and factors like resident interactions and program culture were most influential. Half of applicants favored virtual-only interviews, but the majority wanted a hybrid option going forward. Applicants broadly supported capping interview numbers to reduce the burden on applicants and programs alike.

PubMed

Disparities in the Operative Experience Between Female and Male General Surgery Residents: A Multi-institutional Study From the US ROPE Consortium.

2023

Annals of surgery

Winer LK, Kader S, Abelson JS, Hammaker AC, Eruchalu CN +36 more

Plain English
Across 1,343 general surgery graduates from 20 programs over 11 years, women performed significantly fewer total cases than men, largely due to fewer surgeon junior cases — the core learning role. On multivariable analysis, female sex independently reduced the odds of being a high-volume resident by 26%. The gap appears to be narrowing slowly over time, with women increasing their annual case volume faster than men, but the disparity has not been eliminated.

PubMed

Examining the impact of COVID-19 restrictions on the operative volumes of US general surgery residents.

2022

Surgery

Ammann AM, Cortez AR, Vaysburg DM, Winer LK, Sussman JJ +3 more

Plain English
Case log data showed that the COVID-19 pandemic reduced general surgery resident case volumes nationally, with 2020 graduates completing about 1.5% fewer total cases and 8% fewer chief-level cases than 2019 graduates. At one institution, residents across all training levels performed 42% fewer operations during peak pandemic months. The magnitude of the impact on training quality and future competency warrants continued monitoring.

PubMed

Omission of Adjuvant Chemotherapy in Rectal Cancer Patients with Pathologic Complete Response: a National Analysis.

2021

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Morris MC, Winer LK, Lee TC, Shah SA, Rafferty JF +1 more

Plain English
This study looked at patients with rectal cancer who had a complete response to initial treatment and whether they received recommended follow-up chemotherapy. It found that 32% of these patients received chemotherapy after surgery, but those who did had a five-year survival rate of 92% compared to 85% for those who didn’t. This is important because it shows that follow-up treatment can significantly improve survival rates, yet many patients are not receiving it. Who this helps: This helps rectal cancer patients who may need further treatment after their initial therapy.

PubMed

Hitting the Vasopressor Ceiling: Finding Norepinephrine Associated Mortality in the Critically Ill.

2021

The Journal of surgical research

Singer KE, Sussman JE, Kodali RA, Winer LK, Heh V +5 more

Plain English
This study looked at how different doses of norepinephrine, a medication used to treat critically ill patients, affect survival rates in medical and surgical intensive care units (ICUs). Researchers analyzed data from 661 patients and found that mortality rates increased significantly when norepinephrine doses exceeded certain levels: specifically, a rate above 18 mcg/min or a total dose over 17.6 mg was linked to higher death rates, with trauma patients facing a mortality rate of 41.7% even at low doses of 5 mcg/min. Understanding these dose limits is crucial for doctors to make better decisions about treatment for critically ill patients. Who this helps: This helps doctors treating critically ill patients in ICUs.

PubMed

Evaluating the Impact of ESPAC-1 on Shifting the Paradigm of Pancreatic Cancer Treatment.

2021

The Journal of surgical research

Winer LK, Cortez AR, Ahmad SA, Wima K, Olowokure O +3 more

Plain English
This study looked at how the treatment for pancreatic cancer changed in the U.S. after a key 2004 trial. Between 1998 and 2015, the use of chemotherapy after surgery for pancreatic cancer rose significantly from 2.9% to 51.6%, while the use of chemoradiation dropped from 49.5% to 22.9%. This shift matters because it shows that new research can take time to influence actual treatment practices, even though chemotherapy has proven to be more beneficial for survival than chemoradiation. Who this helps: Patients with pancreatic cancer.

PubMed

Extinguishing burnout: National analysis of predictors and effects of burnout in abdominal transplant surgery fellows.

2021

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Kassam AF, Cortez AR, Winer LK, Conzen KD, El-Hinnawi A +11 more

Plain English
This study looked at burnout in fellows training to become abdominal transplant surgeons. It found that 22.7% of these fellows experienced burnout, and those with lower resilience were more likely to feel burned out. Burnout led to long working hours, severe stress, a high likelihood of considering quitting, and an increased risk of making medical errors, highlighting the need for better support systems to help these doctors. Who this helps: This helps transplant surgery fellows and their patients by improving surgeon well-being and patient care.

PubMed

Acquisition and retention of surgical skills taught during intern surgical boot camp.

2021

American journal of surgery

Kassam AF, Singer KE, Winer LK, Browne D, Sussman JJ +2 more

Plain English
This study looked at how effective a surgical boot camp was in teaching new interns important surgical skills. After attending eight training sessions, interns became faster and better at tasks like knot-tying and skin closure, with significant improvements in completion times (for example, reducing skin closure time from 9.9 minutes to 8.3 minutes). By the end of the year, they maintained these skills and even got better at certain techniques. Who this helps: This benefits new surgical interns as well as the patients they will treat.

PubMed

Gender and ethnic diversity in academic general surgery department leadership.

2021

American journal of surgery

Kassam AF, Taylor M, Cortez AR, Winer LK, Quillin RC

Plain English
This study looked at who leads academic general surgery departments and found that leadership is still largely made up of men and white individuals. Out of 118 programs, 79% of department chairs were white and 85% were men, while only a small number of minority surgeons held leadership roles. Addressing these disparities in leadership is important because increasing diversity can lead to better mentorship and improved patient care. Who this helps: This helps patients and aspiring surgeons by promoting a more diverse leadership that can improve mentorship and healthcare outcomes.

PubMed

Is Surgery Necessary? Endoscopic Management of Post-transplant Biliary Complications in the Modern Era.

2020

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Cortez AR, Morris MC, Brown NG, Winer LK, Safdar K +3 more

Plain English
The study looked at complications with bile ducts that can happen after a liver transplant, focusing on how to manage these issues without surgery. Out of 449 patients who had transplants, 21% developed complications, mainly narrowed bile ducts (59%), leaks (29%), or both (12%). When treated endoscopically, most patients saw positive outcomes—94% for narrowed ducts, and 90% for leaks—showing that non-surgical methods can effectively resolve these issues without increasing risks for patients. Who this helps: Patients who undergo liver transplants benefit the most from these findings.

PubMed

Small Bowel Adenocarcinomas: Impact of Location on Survival.

2020

The Journal of surgical research

Lee TC, Wima K, Morris MC, Winer LK, Sussman JJ +3 more

Plain English
This study looked at small bowel cancers to see how the location of the tumor affects survival rates. Researchers found that tumors in the duodenum (the proximal area) have worse survival outcomes compared to those in the jejunum and ileum (the distal area). Specifically, patients with proximal tumors were more likely to have aggressive cancer types and a lower chance of survival, while those with distal tumors tended to be larger but were associated with better outcomes when treated with certain chemotherapy options. Who this helps: This information helps doctors understand how tumor location affects patient treatment and survival, guiding better care for cancer patients.

PubMed

Enigmatic role of coagulopathy among sepsis survivors: a review of coagulation abnormalities and their possible link to chronic critical illness.

2020

Trauma surgery & acute care open

Winer LK, Salyer C, Beckmann N, Caldwell CC, Nomellini V

Plain English
This research looked at how blood clotting problems in people recovering from sepsis may relate to long-term health issues. It found that patients in intensive care with blood clotting disorders were more likely to face serious complications and higher death rates, with 28-day mortality linked to these abnormalities. Understanding this connection is important as it could help doctors better manage care for sepsis survivors and improve their recovery chances. Who this helps: Patients recovering from sepsis and their healthcare providers.

PubMed

Impact of side-to-side cavocavostomy versus traditional piggyback implantation in liver transplantation.

2020

Surgery

Lee TC, Dhar VK, Cortez AR, Morris MC, Winer LK +6 more

Plain English
This study looked at two different methods of attaching a new liver during transplant surgery: the traditional piggyback method and a newer side-to-side cavocavostomy method. Out of 290 liver transplant patients, those who had the side-to-side method needed fewer blood transfusions and had fewer complications like temporary abdominal closure—2 transfusions compared to 5, and an 8.3% complication rate versus 24.1%. This matters because it suggests that the side-to-side method may be safer and easier for surgeons, potentially leading to better recovery for patients. Who this helps: Liver transplant patients.

PubMed

Resident Operative Experience in Hepatopancreatobiliary Surgery: Exposing the Divide.

2020

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Cortez AR, Winer LK, Katsaros GD, Kassam AF, Shah SA +2 more

Plain English
This study looked at the training experience of general surgery residents in the U.S. regarding hepatopancreatobiliary (HPB) surgery, which includes surgeries on the liver, pancreas, and bile ducts, over 27 years. It found that while the number of surgeries residents performed increased—by 30% for biliary surgeries, 33% for liver surgeries, and 27% for pancreatic surgeries—most of these operations were laparoscopic cholecystectomies, which made up 90% of all biliary procedures. This focus on one type of surgery means that trainees may not get enough varied exposure to other important HPB surgeries, which is concerning for their overall training. Who this helps: This helps surgical residents and educators by highlighting the need for a more balanced surgical training experience.

PubMed

Outcomes of en bloc simultaneous liver-kidney transplantation compared to the traditional technique.

2020

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Lee TC, Cortez AR, Kassam AF, Morris MC, Winer LK +6 more

Plain English
This study looked at two methods for performing a combined liver and kidney transplant: the en bloc technique, where both organs are transplanted together, and the traditional method, where they are done separately. The researchers found that patients who received the en bloc transplant had a shorter time for the kidneys to be without blood supply and a quicker surgery, which could mean less risk during the operation. Overall, the outcomes were similar for both methods, with about 88% of en bloc kidney grafts surviving for a year. Who this helps: This research benefits patients needing a liver and kidney transplant, as it provides options that may lead to better surgery experiences.

PubMed

The impact of medical student interest in surgery on clerkship performance and career choice.

2020

American journal of surgery

Kassam AF, Cortez AR, Winer LK, Kuethe JW, Athota KP +1 more

Plain English
This study explored how interest in surgery affects medical students' performance during their surgical training and their future career choices. Out of 62 students surveyed, 51.6% were interested in surgery, with no minority students expressing that interest, compared to 51.1% of Caucasian and 71.4% of Asian students. Students who were not interested in surgery experienced more emotional exhaustion, scoring 25 on average compared to 20 for interested students, but there was no significant difference in their grades. Who this helps: This information benefits medical schools and educators by highlighting the importance of fostering interest in surgery among all student groups.

PubMed

Exploring the relationship between burnout and grit during general surgery residency: A longitudinal, single-institution analysis.

2020

American journal of surgery

Cortez AR, Winer LK, Kassam AF, Hanseman DJ, Kuethe JW +2 more

Plain English
This study looked at how burnout affects general surgery residents over their training from 2015 to 2018. Researchers found that burnout levels were highest during the first and third years of residency, with the risk of burnout significantly increasing during the third year (nearly 12 times more likely). Additionally, residents who experienced burnout had lower grit scores, which measure perseverance and resilience. This research highlights the importance of addressing burnout in training programs to better support surgical residents and their well-being. Who this helps: This helps residents and residency programs aiming to reduce burnout and improve training experiences.

PubMed

Swipe right for surgical residency: Exploring the unconscious bias in resident selection.

2020

Surgery

Kassam AF, Cortez AR, Winer LK, Baker JE, Hanseman DJ +8 more

Plain English
This study looked at whether the photos applicants provide when applying for surgical residency programs influence selection decisions. Researchers analyzed 422 applications from 2018-2019 and found that certain factors like research experience and the overall photo score impacted interview invitations, but interestingly, the applicants' looks did not affect final selection. Specifically, scores for a photo's perceived professionalism significantly correlated with getting interviews, but this was less influential in final decisions, indicating that while appearance plays a role, other qualifications are ultimately more important. Who this helps: This helps applicants to surgical residency programs by highlighting the importance of qualifications over appearance.

PubMed

Exploring Medical Students' Perceptions of Organ Procurement: Need for a Formalized Medical Student Curriculum.

2020

Journal of surgical education

Winer LK, Vivero MP, Scully BF, Cortez AR, Kassam AF +4 more

Plain English
Medical students who assisted with organ procurements reported the experience was meaningful but lacked any formal educational structure. A survey of students who participated over several years found strong interest in surgery and donation but gaps in knowledge and guidance. The authors call for a standardized curriculum to make procurement education consistent and impactful.

PubMed

Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy.

2019

Shock (Augusta, Ga.)

Xia BT, Beckmann N, Winer LK, Kim Y, Goetzman HS +5 more

Plain English
This study looked at how the medication amitriptyline, commonly used as an antidepressant, affects blood clotting during sepsis, a severe infection. The researchers found that in mice with sepsis, amitriptyline treatment prevented dangerous changes in blood coagulation that typically occur, keeping their coagulation levels similar to healthy mice. This is important because it suggests that amitriptyline could be a useful treatment for sepsis, potentially reducing complications like excess bleeding or blood clots. Who this helps: This helps patients suffering from sepsis and their doctors by offering a new treatment option.

PubMed

Predictors of medical student success on the surgery clerkship.

2019

American journal of surgery

Cortez AR, Winer LK, Kim Y, Hanseman DJ, Athota KP +1 more

Plain English
This study looked at what factors predict how well medical students perform during their surgery rotation. It found that students who scored higher on their USMLE Step 1 exam and demonstrated more grit, or persistence, were more likely to achieve higher grades. Specifically, students with honors grades were more often individual learners with a grit score of 8.9 compared to 7.5 for others, highlighting the need for better ways to assess students' clinical skills beyond just tests. Who this helps: This information benefits medical educators and program directors looking to support student success in surgery training.

PubMed

Perioperative blood transfusions following hepatic lobectomy: A national analysis of academic medical centers in the modern era.

2019

HPB : the official journal of the International Hepato Pancreato Biliary Association

Dhar VK, Wima K, Lee TC, Morris MC, Winer LK +3 more

Plain English
This study looked at how often patients undergoing liver surgery (hepatic lobectomy) needed blood transfusions at top medical centers between 2011 and 2014. Out of nearly 6,500 patients, over 20% received blood during their hospital stay, with 35% of those needing more than 5 blood units. The findings show that patients who needed more blood had worse outcomes, such as higher chances of being readmitted (23.4% vs. 13.5% for those who didn't need transfusions) and longer hospital stays (9 days vs. 6 days). Who this helps: This information benefits patients and healthcare providers by highlighting the risks associated with higher blood transfusion needs during liver surgeries.

PubMed

The Impact of Tumor Location on Resection and Survival for Pancreatic Ductal Adenocarcinoma.

2019

The Journal of surgical research

Winer LK, Dhar VK, Wima K, Morris MC, Lee TC +3 more

Plain English
This study looked at how the location of pancreatic cancer tumors affects treatment outcomes and survival rates. Researchers found that tumors in the head of the pancreas were more likely to be detected at an earlier stage and to be operable compared to those in the body or tail, with 27.9% of head tumors successfully removed versus only about 10.7% of body tumors and 17% of tail tumors. However, even with surgery, patients with head tumors had worse survival rates than those with body and tail tumors, which raises questions about why this is happening. Who this helps: This information is valuable for doctors treating pancreatic cancer and can guide better diagnosis and treatment strategies for patients.

PubMed

Consumptive coagulopathy is associated with organ dysfunction during PICS.

2019

American journal of physiology. Lung cellular and molecular physiology

Winer LK, Beckmann N, Veile RA, Goodman MD, Caldwell CC +1 more

Plain English
This study looked at how a severe infection that can lead to persistent inflammation and weakness in the body, called PICS, affects blood clotting in mice. Researchers found that during PICS, mice had much more clot formation in their lungs and worse lung function, specifically showing a nearly sevenfold increase in small blood clots in the lungs and difficulties in breathing. Understanding these clotting issues is important because they could worsen organ damage and failure in patients recovering from severe infections. Who this helps: This helps doctors treating patients recovering from severe infections and potentially improves patient outcomes.

PubMed

Amitriptyline Reduces Inflammation and Mortality in a Murine Model of Sepsis.

2019

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Xia BT, Beckmann N, Winer LK, Pugh AM, Pritts TA +3 more

Plain English
This study looked at how the drug amitriptyline (AT) can help mice with sepsis, a severe infection that causes widespread inflammation. The researchers found that mice treated with AT had improved survival rates and less lung damage, with a notable decrease in harmful inflammatory markers and an increase in a protective protein called IL-10. Specifically, AT-treated mice showed a significant reduction in certain inflammatory proteins and improved IL-10 levels, suggesting that it could be an effective treatment option for controlling inflammation in sepsis. Who this helps: This helps patients suffering from sepsis and their doctors by potentially offering a new treatment option to reduce inflammation and improve survival.

PubMed

Incidence and Long-term Outcomes of Patients Requiring Early Reoperation After HIPEC.

2019

The Journal of surgical research

Lee TC, Wima K, Morris MC, Winer LK, Sussman JJ +2 more

Plain English
This study looked at patients who had a specific type of cancer surgery followed by chemotherapy (HIPEC) to see how often they needed additional surgery due to complications. Out of 141 patients, 15 (about 10.6%) needed early reoperations, typically within 18 days after the initial procedure. Those who had to undergo reoperations faced a longer hospital stay of 19 days compared to 9 days for those who didn't, and they had a much lower overall survival rate after three years (38% versus 72%). Who this helps: This information is useful for doctors and patients as it highlights the risks of complications following HIPEC and the importance of minimizing them for better outcomes.

PubMed

Flat epithelial atypia and the risk of sampling error: Determining the value of excision after image-guided core-needle biopsy.

2019

American journal of surgery

Winer LK, Hinrichs BH, Lu S, Hanseman D, Huang Y +3 more

Plain English
This study looked at how often flat epithelial atypia (FEA), a specific breast tissue finding, was misdiagnosed after a type of biopsy called core-needle biopsy. Among 27 biopsies reviewed, only 44.4% were correctly identified as FEA, and some lesions were found to be early (11.1%) or invasive cancer upon further examination. This matters because it highlights the importance of further surgical removal of suspicious findings, as some may turn out to be cancerous or pose a higher risk for developing cancer. Who this helps: This helps patients with breast abnormalities and their doctors by guiding better management decisions.

PubMed

Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for patients at High-Risk of Peritoneal Metastases.

2019

Surgical oncology

Morris MC, Dhar VK, Stevenson MA, Winer LK, Lee TC +5 more

Plain English
This study looked at a treatment called hyperthermic intraperitoneal chemotherapy (HIPEC) for patients at high risk of cancer spreading within the abdomen. Researchers followed 37 patients for over five years and found that 77% were free from cancer recurrence after five years, while all patients survived, indicating the treatment was both safe and effective. This matters because it provides a promising option for patients who are at high risk of their cancer progressing after surgery. Who this helps: Patients with high-risk abdominal cancers.

PubMed

The Impact of Medical Student Burnout on Surgery Clerkship Performance.

2019

Journal of surgical education

Cortez AR, Winer LK, Kassam AF, Kuethe JW, Athota KP +1 more

Plain English
This study looked at the burnout levels of third-year medical students during their surgery training and whether it affected their performance. The researchers found that 22.6% of students reported burnout before the training, which dropped to 17.7% after, but this change wasn’t significant. Students who experienced burnout had lower "grit" scores, indicating they may have less perseverance, yet overall, burnout did not negatively affect their performance or experiences in the program. Who this helps: This research benefits medical students and educators by highlighting the importance of resilience while not increasing concerns about burnout affecting their training performance.

PubMed

See None, Do Some, Teach None: An Analysis of the Contemporary Operative Experience as Nonprimary Surgeon.

2019

Journal of surgical education

Cortez AR, Winer LK, Kassam AF, Hanseman DJ, Kuethe JW +2 more

Plain English
This study looked at how the surgical training for general surgery residents in the U.S. has changed from 1990 to 2018, focusing on their roles as first assistants and teaching assistants during surgeries. The research found that the number of surgeries where residents acted as first assistants dropped from 21.8% to just 2.5%, and as teaching assistants from 7.4% to 3.5%. This is significant because it shows a concerning decline in hands-on surgical experience for trainees, which is crucial for their skills development. Who this helps: This benefits medical educators and the surgery residency program, ensuring they can maintain effective training standards for future surgeons.

PubMed

Use, Safety, and Effectiveness of Viremic Hepatitis B Virus Donor Livers: A Potential Opportunity to Expand the Donor Pool.

2019

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Lee TC, Kaiser TE, Luckett K, Wima K, Winer LK +7 more

PubMed

Gas off, room lights on: Shedding light on the surgical resident's experience in open and laparoscopic surgery.

2019

Surgery

Quillin RC, Cortez AR, Garcia MA, Winer LK, Kassam AF +2 more

Plain English
This study looked at how the surgical training experiences of medical residents have changed over the past 25 years, specifically comparing open surgery to laparoscopic (minimally invasive) surgery. Between 1994 and 2018, over 26,000 surgical residents graduated, and while they collectively performed around 955 major surgeries each, the study found an increase of nearly 10 laparoscopic surgeries performed each year and a decrease of over 3 open surgeries per year. This shift is important because it raises concerns that new surgeons may not be getting enough experience with open surgeries, which could be needed in more complex cases. Who this helps: This benefits surgical residents and their future patients by highlighting the need for balanced training in different surgical techniques.

PubMed

The Impact of a Comprehensive Resident Curriculum and Required Participation in "This Week in SCORE" on General Surgery ABSITE Performance and Well-Being.

2019

Journal of surgical education

Winer LK, Cortez AR, Kassam AF, Quillin RC, Goodman MD +3 more

Plain English
This study looked at how a mandatory online learning program for surgical residents, called "This Week in SCORE" (TWIS), affected their test scores and overall well-being. After making TWIS participation required, the average test scores on the American Board of Surgery In-Training Examination increased from the 65th percentile to the 77th percentile, and satisfaction with the learning environment improved significantly. These findings suggest that structured learning and regular assessments can lead to better performance and reduced feelings of burnout among surgical residents. Who this helps: This benefits surgical residents and their education programs.

PubMed

Perioperative Net Fluid Balance Predicts Pancreatic Fistula After Pancreaticoduodenectomy.

2018

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

Winer LK, Dhar VK, Wima K, Lee TC, Morris MC +3 more

Plain English
This research studied how the amount of fluid given to patients after surgery affects the risk of developing pancreatic fistulas—a complication after pancreatic surgery. Among 104 patients who underwent the surgery, 17.3% developed this complication. The findings showed that patients who received a lot of fluid in the first 72 hours after surgery had a higher risk of developing pancreatic fistulas (31.4%) compared to those with lower fluid levels (11.4% for medium and 8.8% for low fluid balance). Who this helps: This helps doctors in managing fluids for patients undergoing pancreatic surgery to reduce the risk of complications.

PubMed

An update on gastric cancer.

2016

Current problems in surgery

Ahmad SA, Xia BT, Bailey CE, Abbott DE, Helmink BA +7 more

PubMed

Frequent Co-Authors

Alexander R Cortez Ralph C Quillin Al-Faraaz Kassam Mackenzie C Morris Tiffany C Lee R Cutler Quillin Jeffrey J Sussman Shimul A Shah Syed A Ahmad Michael D Goodman

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.