Dr. Maestas primarily studies blacklegged ticks, which are known carriers of Lyme disease. Her research examines how these ticks adapt to different environments across the United States, revealing significant genetic differences based on geography. She has also investigated the types of bacteria in ticks that cause Lyme disease, discovering multiple strains that can influence the severity of infections. Additionally, she looks at the ecological factors that contribute to the prevalence of Lyme disease in various regions, helping to inform prevention efforts.
Key findings
Genetic analysis of 92 blacklegged ticks revealed three main population groups related to geography, indicating that ticks in the north and south have been isolated for over 50,000 years.
In Delaware, 40% of tick samples carried multiple strains of Borrelia burgdorferi, the bacteria that causes Lyme disease, highlighting an increased risk of severe disease in the area.
The study on host behavior showed that ticks in the north prefer small mammals like rodents, which carry Lyme bacteria, while southern ticks prefer reptiles like lizards, which do not pose a risk for the disease.
Frequently asked questions
Does Dr. Maestas study Lyme disease?
Yes, Dr. Maestas focuses on Lyme disease, particularly the ticks that carry the bacteria responsible for it.
What treatments has Dr. Maestas researched?
Dr. Maestas' work informs prevention strategies rather than specific treatments, highlighting the risks associated with different tick populations.
Is Dr. Maestas' work relevant to patients at risk for tick-borne diseases?
Yes, her research directly benefits patients at risk by identifying high-risk areas and informing public health measures.
What other ticks does Dr. Maestas study?
She also studies the Asian longhorned tick, exploring its origins and spread in the United States.
How can Dr. Maestas' research help public health?
Her findings help public health officials manage and reduce the risk of Lyme disease and other tick-borne illnesses.
Publications in plain English
Genome resequencing reveals population divergence and local adaptation of blacklegged ticks in the United States.
2024
Molecular ecology
Schoville SD, Burke RL, Dong DY, Ginsberg HS, Maestas L +2 more
Plain English This study looked at the genetic differences between blacklegged ticks in the United States to understand how they move and adapt to their environments. Researchers analyzed the genomes of 92 ticks and found that their populations are separated into three main groups based on geography, showing that ticks in the north and south have been isolated for at least 50,000 years. Additionally, they found evidence that ticks have adapted to survive based on their local conditions and that gene flow between populations is limited to a range of a few hundred kilometers.
Who this helps: This research benefits public health officials and patients at risk of tick-borne diseases.
Prevalence of Borrelia burgdorferi and diversity of its outer surface protein C (ospC) alleles in blacklegged ticks (Ixodes scapularis) in Delaware.
2023
Ticks and tick-borne diseases
Shifflett SA, Wiedmeyer T, Kennedy A, Maestas L, Buoni M +2 more
Plain English This study looked at the types of a specific gene (ospC) in the Borrelia burgdorferi bacteria found in blacklegged ticks in Delaware, which causes Lyme disease. Researchers found that 40% of the tick samples had multiple strains of the bacteria, and the types of strains present were more similar in nearby locations. This information is important because it shows that certain strains linked to severe Lyme disease are common in Delaware, which helps us understand the risk of infection in the area.
Who this helps: This helps patients and public health officials manage and reduce the risk of Lyme disease.
Why Lyme disease is common in the northern US, but rare in the south: The roles of host choice, host-seeking behavior, and tick density.
2021
PLoS biology
Ginsberg HS, Hickling GJ, Burke RL, Ogden NH, Beati L +11 more
Plain English This study examined why Lyme disease is more common in the northern United States compared to the south. Researchers found that in northern regions, ticks often attach to small mammals like rodents, which are effective carriers of the Lyme bacteria, while in the south, ticks prefer reptiles such as lizards, which do not carry the disease. This understanding is important because it helps explain the distribution of Lyme disease and can aid in prevention efforts.
Who this helps: This helps patients and healthcare providers by informing Lyme disease risk assessments and prevention strategies.
Correction: Why Lyme disease is common in the northern US, but rare in the south: The roles of host choice, host-seeking behavior, and tick density.
2021
PLoS biology
Ginsberg HS, Hickling GJ, Burke RL, Ogden NH, Beati L +11 more
Plain English This research examines why Lyme disease is more frequent in the northern United States than in the southern regions. The study found that specific animals (hosts) that ticks prefer to bite are more available in the north, leading to higher tick populations and more cases of Lyme disease. Understanding these patterns is important for better prevention and treatment strategies in areas where Lyme disease is more prevalent.
Who this helps: This benefits patients at risk for Lyme disease and healthcare providers treating these patients.
First glimpse into the origin and spread of the Asian longhorned tick, Haemaphysalis longicornis, in the United States.
2020
Zoonoses and public health
Egizi A, Bulaga-Seraphin L, Alt E, Bajwa WI, Bernick J +23 more
Plain English This study looked at the Asian longhorned tick, first found in the U.S. in 2017, to understand where it came from and how it spreads. The researchers analyzed tick samples from nine states and compared them to samples from Asia and other regions, uncovering three unique genetic types of the tick in the U.S. that likely originated from northeast Asia. The findings highlight the importance of controlling the spread of these ticks, as they can travel long distances with pets and livestock, which impacts public health and agricultural practices.
Who this helps: This helps patients, veterinarians, and public health officials.
Parasitology, virology, and serology of free-ranging coyotes (Canis latrans) from central Georgia, USA.
2014
Journal of wildlife diseases
Gates M, Gerhold RW, Wilkes RP, Gulsby WD, Maestas L +3 more
Plain English Researchers studied 31 coyotes in central Georgia to see if they carried certain parasites and viruses. They found that 16 of the coyotes had heartworms, and all of the coyotes tested had antibodies against canine parvovirus, while 48% had antibodies for canine distemper virus. This information is important because it shows that coyotes can harbor diseases that may spread to domestic dogs, highlighting the need to monitor disease transmission between these animals.
Who this helps: This helps veterinarians and pet owners by raising awareness of potential health risks related to dog diseases.
Russell L Burke Howard S Ginsberg Jean I Tsao Graham J Hickling Nicholas H Ogden Lorenza Beati Roger A LeBrun Isis M Arsnoe Richard Gerhold Seungeun Han
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Plain-English summaries generated by AI.
Not medical advice.