Dr. Mazow studies several conditions related to eye health, including rare tumors such as conjunctival extramedullary plasmacytoma, which can occur in the eyelid. He also investigates eye alignment issues, like strabismus, in children with spina bifida, aiming to identify factors that influence these conditions. Furthermore, he examines treatment methods like alternating occlusion for infants with esotropia, a condition where the eyes are crossed, to understand how they affect surgical outcomes. His research into botulinum toxin treatment offers insights into recovering eye function in patients with sudden muscle paralysis affecting eye movement.
Key findings
In a case of primary conjunctival extramedullary plasmacytoma, a patient showed no signs of tumor recurrence after six months without additional treatment.
In a study involving 112 children with spina bifida, it was found that factors like lower birth weight and younger gestational age increased the likelihood of developing strabismus in 42 children.
For infants with esotropia, alternative occlusion did not impact the overall surgical success rate; 75% achieved proper eye alignment post-surgery, and 91% of those aligned at six weeks remained so after one year.
In a study of 34 patients with acute sixth nerve palsy treated with botulinum toxin, 71% improved without surgery, compared to only 31% of untreated patients.
Frequently asked questions
Does Dr. Mazow study eye conditions in children?
Yes, he focuses on various eye conditions in children, particularly strabismus and esotropia.
What treatments has Dr. Mazow researched for eye muscle paralysis?
He has researched the use of botulinum toxin injections to treat acute sixth and third nerve palsy, which significantly helps in recovery.
Is Dr. Mazow's work relevant for patients with eye tumors?
Absolutely, he has published findings on rare eye tumors, helping medical professionals better understand and treat these conditions.
What is strabismus and how is it related to spina bifida?
Strabismus is an eye alignment issue where the eyes do not point in the same direction. Dr. Mazow studies its prevalence and causes in children with spina bifida.
Publications in plain English
Primary Conjunctival Extramedullary Plasmacytoma: A Case Report and Review of the Literature.
2025
Ophthalmic plastic and reconstructive surgery
Duncan NB, McCoskey M, Goodyear K, Belinsky I, Mazow M
Plain English This study looked at a 77-year-old man who had a painless growth on his lower eyelid discovered during a routine eye exam. After further tests, doctors diagnosed him with a type of tumor called primary conjunctival extramedullary plasmacytoma, which did not spread beyond the eye area. Remarkably, six months later, he showed no signs of the tumor returning, even without additional treatment.
Who this helps: This information benefits doctors by enhancing their understanding of rare eye tumors, aiding in quicker and more accurate diagnoses for patients.
Factors associated with strabismus in spina bifida myelomeningocele.
2012
Journal of pediatric ophthalmology and strabismus
Anderson HA, Stuebing KK, Buncic R, Mazow M, Fletcher JM
Plain English This study focused on the relationship between eye alignment issues, known as strabismus, and various factors in children with spina bifida myelomeningocele (SBM). Among 112 children aged 3 to 18, 42 were found to have strabismus. It was determined that lower birth weight, younger gestational age, and having had shunt revisions were linked to a higher likelihood of developing strabismus, especially when the spinal lesions were closer to the brain.
Who this helps: This helps doctors and caregivers of children with spina bifida by highlighting factors that may increase the risk of eye problems.
A prospective study of alternating occlusion before surgical alignment for infantile esotropia: one-year postoperative motor results.
2006
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
Ing MR, Norcia A, Stager D, Black B, Hoffman R +4 more
Plain English This study investigated whether a specific treatment called alternating occlusion could improve the surgical outcomes for infants with a condition known as esotropia, where the eyes are crossed. Researchers followed 44 infants and found that 75% were aligned correctly after their first surgery, and the same percentage was still well-aligned one year later, regardless of whether they received alternating occlusion before surgery or not. This matters because it shows that adding alternating occlusion doesn’t change the success rate of the surgery or improvement in eye alignment.
Who this helps: This helps infants with esotropia and their families.
A prospective study of alternating occlusion prior to surgical alignment for infantile esotropia: one-year postoperative motor results.
2005
Transactions of the American Ophthalmological Society
Ing MR, Norcia A, Stager D, Black B, Hoffman R +4 more
Plain English This study looked at whether a technique called alternating occlusion, where one eye is covered to strengthen the other, improves outcomes for infants with a condition called infantile esotropia, where the eyes are misaligned. The researchers followed 44 patients who either received this treatment or no extra treatment before surgery; they found that 75% were properly aligned after their first surgery, and 91% of those who were aligned at 6 weeks remained aligned a year later. However, alternating occlusion did not significantly change the results compared to those who did not receive this treatment before surgery.
Who this helps: This helps doctors and parents of infants with eye misalignment.
Botulinum toxin treatment of acute sixth and third nerve palsy.
1988
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Metz HS, Mazow M
Plain English This study looked at how botulinum toxin injections help patients with sudden eye muscle paralysis, specifically focusing on 34 patients with sixth nerve palsy and 9 with third nerve palsy. The results showed that 71% of the patients with sixth nerve palsy treated with the toxin improved without needing surgery, compared to only 31% of those who did not receive the treatment. For the third nerve palsy patients, all experienced recovery in their eye movement and none needed surgery. This is important because it offers a potential treatment option for patients with these conditions, helping them recover their eye function more effectively.
Who this helps: This benefits patients suffering from acute sixth and third nerve palsy.