Dr. Mostovych studies procedures and treatments for various heart issues, particularly persistent atrial fibrillation (AF) and angina. For AF, he explores a combined approach called the Convergent hybrid procedure, which merges two methods to provide better patient outcomes compared to traditional techniques. In his work on angina management, he examines the effectiveness of transmyocardial revascularization (TMR) alongside bypass surgery to improve blood flow and alleviate chest pain for patients who have not found relief through standard treatments. His research is pivotal for helping patients with severe heart conditions achieve better quality of life.
Key findings
In the CONVERGE trial, the Convergent hybrid procedure aimed to improve success rates for treating persistent AF, which currently succeeds in less than 40% of cases, involving 153 participants.
In a study of transmyocardial revascularization, patients had a mean angina score of 0.4 after TMR plus bypass surgery, compared to 0.7 for those who only had bypass, with 10% of bypass-only patients experiencing severe angina versus none in the TMR group.
In a trial comparing TMR and bypass, patients who underwent both procedures had a lower mortality rate of 1.5% compared to 7.6% in the bypass-only group, and a slightly higher one-year survival rate of 95% versus 89%.
Frequently asked questions
Does Dr. Mostovych study atrial fibrillation?
Yes, he investigates new treatments for persistent atrial fibrillation, including a combined procedure that could enhance treatment success.
What treatments has Dr. Mostovych researched?
He has researched transmyocardial revascularization and its effectiveness when used alongside traditional bypass surgery for heart patients.
Is Dr. Mostovych's work relevant to patients with chest pain?
Absolutely, his studies on transmyocardial revascularization aim to provide better relief for patients suffering from chronic chest pain due to inadequate blood flow.
Publications in plain English
Convergence of Epicardial and Endocardial RF Ablation for the Treatment of Symptomatic Persistent AF (CONVERGE Trial): Rationale and design.
2020
American heart journal
DeLurgio DB, Ferguson E, Gill J, Blauth C, Oza S +4 more
Plain English The CONVERGE trial studied a new treatment for patients with persistent atrial fibrillation (AF), a heart condition affecting more than 33 million people globally. It compared a dual approach called the Convergent hybrid procedure to the traditional endocardial catheter ablation, aiming for more effective results, especially since current treatments succeed in less than 40% of cases. The study includes 153 participants to see which method helps patients become free from AF without needing anti-arrhythmic drugs for at least three months.
Who this helps: This helps patients suffering from persistent atrial fibrillation and their doctors.
Adjunctive transmyocardial revascularization: five-year follow-up of a prospective, randomized trial.
2004
The Annals of thoracic surgery
Allen KB, Dowling RD, Schuch DR, Pfeffer TA, Marra S +7 more
Plain English This study looked at 263 patients who were at risk of not having enough blood flow to their hearts after surgery. It found that patients who had an additional treatment called transmyocardial revascularization (TMR) along with their bypass surgery experienced less chest pain (angina) over five years compared to those who only had bypass surgery. Specifically, the TMR group had a mean angina score of 0.4 compared to 0.7 for the bypass-only group, and none of the TMR patients had severe angina, while 10% of bypass-only patients did.
Who this helps: This benefits heart patients who may not get enough relief from angina through traditional bypass surgery alone.
Transmyocardial laser revascularization combined with coronary artery bypass grafting: a multicenter, blinded, prospective, randomized, controlled trial.
2000
The Journal of thoracic and cardiovascular surgery
Allen KB, Dowling RD, DelRossi AJ, Realyvasques F, Lefrak EA +6 more
Plain English The study looked at the safety and effectiveness of a heart procedure called transmyocardial revascularization combined with traditional heart bypass surgery in 263 patients who couldn't get complete relief from heart issues with bypass alone. The researchers found that those who had both procedures had a lower risk of dying during or shortly after surgery (1.5% vs. 7.6%) and needed less medication support after the operation. While these patients showed slightly better survival rates after one year (95% versus 89%), the relief from chest pain and exercise ability was similar for both groups after 12 months.
Who this helps: This research benefits patients with severe heart issues who are not suitable candidates for traditional bypass surgery alone.
Plain English This study looked at a 75-year-old man who developed a severe infection in a blood vessel due to an abscess from his appendix. This condition, called aortic sepsis, was linked to a rare placement of the appendix behind the intestinal tract, which allowed the infection to spread to the aorta. The treatment involved removing the affected tissue and repairing the blood vessel, which successfully cured the patient.
Who this helps: This information benefits doctors treating similar cases and helps improve patient outcomes.
David B DeLurgio Edward Ferguson Jaswinder Gill Christopher Blauth Saumil Oza Yashasvi Awasthi Nfii Ndikintum Karl Crossen Keith B Allen Robert D Dowling
Physician data sourced from the
NPPES NPI Registry
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Publication data from
PubMed
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Plain-English summaries generated by AI.
Not medical advice.