Dr. Knesek studies how treatments for conditions like osteoarthritis and issues arising from hip replacement surgeries can be affected by financial backing. In one of his major research areas, he investigated the impact of industry funding on studies involving hyaluronic acid injections for knee osteoarthritis. His findings revealed that more than 62% of the studies were funded by companies selling these injections, which tended to report only positive outcomes. Additionally, he has worked on creating better surgical methods to ensure that patients undergoing hip replacement surgery have equal leg lengths, preventing painful complications related to leg length discrepancies.
Key findings
In a review of 48 studies on hyaluronic acid injections for knee osteoarthritis, 62.5% were funded by the companies selling these injections.
Only 6.25% of the studies had no financial ties to the industry, and 35% of those reported that the injections were no more effective than placebo (fake injections).
A new measurement tool tested on 31 hip replacement patients ensured that leg-length differences were kept to less than 2 millimeters on average, leading to improved patient outcomes.
Frequently asked questions
Does Dr. Knesek study osteoarthritis?
Yes, Dr. Knesek researches treatments for osteoarthritis, particularly the effects of hyaluronic acid injections.
What treatments has Dr. Knesek researched?
He has looked into hyaluronic acid injections for knee osteoarthritis and developed a new technique to ensure equal leg lengths in hip replacement surgeries.
Is Dr. Knesek's work relevant to patients undergoing hip surgery?
Absolutely, his work directly addresses the challenges faced by patients during hip replacement surgeries, particularly in maintaining leg length.
How does funding affect medical studies according to Dr. Knesek?
Dr. Knesek found that studies funded by injection companies often do not report negative results, raising concerns about biases in reported outcomes.
What innovative methods has Dr. Knesek developed?
He has created a new measurement tool for surgeons to ensure precise leg lengths during hip replacements, significantly enhancing patient care.
Publications in plain English
Arthroscopic treatment of type II superior labral anterior to posterior (SLAP) lesions in a younger population: minimum 2-year outcomes are similar between SLAP repair and biceps tenodesis.
2021
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Dunne KF, Knesek M, Tjong VK, Riederman BD, Cogan CJ +4 more
Plain English This study looked at two different surgical treatments for young people aged 15 to 40 with a specific shoulder injury known as a type II SLAP lesion. It compared biceps tenodesis, which involves relocating a tendon, with labral repair, which fixes the torn part of the shoulder. The research found that over at least two years, patients experienced similar levels of pain relief and satisfaction from both treatments, with 63% of those who had tenodesis and 50% of those who had repair returning to their previous sports levels.
Who this helps: This benefits younger patients with SLAP injuries looking for effective treatment options.
Efficacy of Celecoxib for Early Postoperative Pain Management in Hip Arthroscopy: A Prospective Randomized Placebo-Controlled Study.
2017
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Kahlenberg CA, Patel RM, Knesek M, Tjong VK, Sonn K +1 more
Plain English This study looked at whether taking 400 mg of celecoxib an hour before hip arthroscopy surgery could help reduce pain and speed up recovery. The results showed that patients who took celecoxib reported lower pain scores (4.6) one hour after surgery compared to those who took a placebo (5.4), and they also left the recovery room faster (152.9 minutes for celecoxib vs. 172.9 minutes for placebo). Although there was no meaningful difference in the amount of narcotics used, the findings suggest that celecoxib can effectively help manage immediate postoperative pain and improve discharge times.
Who this helps: Patients undergoing hip arthroscopy surgery.
Patterns of strain and the determination of the safe arc of motion after subscapularis repair--A biomechanical study.
2016
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Knesek M, Brunfeldt A, Korenczuk C, Jepsen KJ, Robbins CB +4 more
Plain English This study looked at how the subscapularis tendon in the shoulder behaves under motion after surgery to repair it. They found that during certain movements, like external rotation and abduction, the inferior subscapularis tendon showed high strain (over 3% in 100% of cases), which suggests it is more sensitive to stress than the superior tendon. Understanding these strain patterns helps guide rehabilitation after surgery, ensuring that patients can move safely and recover effectively.
Who this helps: This helps patients recovering from shoulder surgery.
Assessment of Intraoperative Intra-articular Morphine and Clonidine Injection in the Acute Postoperative Period After Hip Arthroscopy.
2016
Orthopaedic journal of sports medicine
Cogan CJ, Knesek M, Tjong VK, Nair R, Kahlenberg C +3 more
Plain English This study looked at the effects of injecting morphine and clonidine into the hip joint during surgery for hip problems. Among 43 patients, those who received this combination used 17 milliequivalents less opioids after surgery compared to those who didn't get the injection, which is a significant reduction. This is important because lowering the amount of opioids needed after surgery can reduce side effects and improve recovery for patients.
Who this helps: This benefits patients undergoing hip arthroscopy.
Shoulder Arthroplasty Outcomes in Patients With Multiple Reported Drug Allergies: Does Number of Drug Allergies Have an Effect on Outcome?
2016
Orthopaedic journal of sports medicine
Rosenthal BD, Knesek MJ, Kahlenberg CA, Mai H, Saltzman MD
Plain English This study looked at how having multiple drug allergies affects the recovery of patients who undergo shoulder replacement surgery. Researchers examined the results of surgery in 98 patients and found no significant differences in pain levels, shoulder movement, or patient satisfaction based on whether patients had no allergies, a single allergy, or multiple allergies. This matters because it suggests that having drug allergies does not negatively impact the success of shoulder arthroplasty.
Who this helps: This helps patients undergoing shoulder surgery, especially those with drug allergies.
New Developments in the Use of Biologics and Other Modalities in the Management of Lateral Epicondylitis.
2015
BioMed research international
Kahlenberg CA, Knesek M, Terry MA
Plain English This research paper looks at ways to treat lateral epicondylitis, a common condition that causes elbow pain and can interfere with daily activities. It found that while corticosteroids are often used, they might actually hinder healing. Instead, treatments like platelet-rich plasma (PRP) and stem cell therapy, which aim to deliver healing substances directly to the injured tendon, are being explored as potentially better options.
Who this helps: This benefits patients suffering from elbow pain, particularly those with persistent issues.
Nair R, Kahlenberg CA, Patel RM, Knesek M, Terry MA
Plain English This study looked at a new way to perform biceps tenodesis, a surgery to fix problems with the long head of the biceps tendon. The researchers developed an all-arthroscopic method that places the tendon attachment below the bicipital groove, which can help prevent pain and other complications that come with traditional open surgery. This new approach aims to be safer and more effective for patients.
Who this helps: Patients suffering from biceps tendon issues.
Osteochondral injury after acute patellar dislocation in children and adolescents.
2013
Journal of pediatric orthopedics
Seeley MA, Knesek M, Vanderhave KL
Plain English This study looked at the injuries that can happen to the knee in children and teenagers who experience a first-time dislocation of the kneecap (patella). Out of 122 young patients, 46 were found to have osteochondral injuries, meaning damage to the bone and cartilage, which often went unnoticed on initial X-rays. The findings showed that injuries to certain areas of the knee, especially those on weight-bearing surfaces, led to worse recovery scores, with patients who had damage to the lateral femoral condyle scoring an average of 72.3, compared to 91.1 for those with patellar injuries.
Who this helps: This research benefits doctors and orthopedic specialists treating young patients with knee injuries.
Diagnosis and management of superior labral anterior posterior tears in throwing athletes.
2013
The American journal of sports medicine
Knesek M, Skendzel JG, Dines JS, Altchek DW, Allen AA +1 more
Plain English This study looked at injuries to the superior glenoid labrum, which are common in athletes who throw, such as baseball players. Researchers found that these injuries can cause significant shoulder pain and may be challenging to diagnose because they often occur alongside other shoulder problems. They emphasized the importance of using advanced imaging techniques and understanding how to effectively treat these injuries, either through rehabilitation or surgery.
Who this helps: This benefits throwing athletes and their doctors by improving diagnosis and treatment strategies for shoulder injuries.
Novel method for ensuring leg length in total hip arthroplasty.
2013
Orthopedics
Maratt JD, Weber AE, Knesek M, Lien JR, Urquhart AG
Plain English Surgeons replacing hip joints often accidentally make one leg slightly longer or shorter than the other, which causes pain and walking problems for patients. This paper describes a new measurement tool that surgeons can use during hip replacement surgery to ensure both legs end up exactly the same length.
The researchers tested their method on 31 hip replacement patients and found that the new technique kept leg-length differences to less than 2 millimeters on average—essentially perfect alignment that patients won't notice or feel.
Conflict of interest in the assessment of hyaluronic acid injections for osteoarthritis of the knee: an updated systematic review.
2013
The Journal of arthroplasty
Printz JO, Lee JJ, Knesek M, Urquhart AG
Plain English Researchers looked at 48 studies testing hyaluronic acid injections for knee arthritis and checked who paid for them. They found that 62.5% were funded by the companies selling these injections, while only 6.25% had no industry money involved.
Studies paid for by injection companies never reported negative results, but 35% of studies with no company ties found the injections worked no better than fake injections.
This matters because it shows money influences what researchers conclude—companies funding studies are getting the results they want to see.
Inflammatory biomarker profiling in elderly patients with acute hip fracture treated with heparins.
2010
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Knesek MJ, Litinas E, Adiguzel C, Hopkinson W, Hoppensteadt D +2 more
Plain English This study looked at blood samples from elderly patients who had hip fractures and were treated with two types of blood thinners: enoxaparin and unfractionated heparin. Researchers found that a specific protein marker appeared in most patients shortly after surgery, with 80.3% showing it on the first day after surgery and 87.8% on the third day. Understanding these biomarkers is important because it can help doctors monitor the health and recovery of elderly patients after hip fracture surgery, allowing for better care and management of potential complications.
Who this helps: This helps elderly patients recovering from hip fractures and their doctors.
Michael Knesek Cynthia A Kahlenberg Michael A Terry Vehniah K Tjong Asheesh Bedi Kevin F Dunne Charles J Cogan Ronak M Patel Rueben Nair Answorth A Allen
Physician data sourced from the
NPPES NPI Registry
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Publication data from
PubMed
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Plain-English summaries generated by AI.
Not medical advice.