Bivalirudin versus unfractionated heparin during percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndrome initially treated with fondaparinux: results from an international, multicenter, randomized pilot study (SWITCH III).
2013Journal of interventional cardiology
Waksman R, Bertrand O, Driesman M, Gruberg L, Rossi J +5 more
Plain English
This study looked at two anticoagulant medications—bivalirudin and unfractionated heparin (UFH)—to see which is safer for patients with acute coronary syndrome (ACS) undergoing a procedure called percutaneous coronary intervention (PCI) after being treated with fondaparinux. Among 100 patients, major bleeding occurred in just one patient treated with bivalirudin (2%) and none in the UFH group. The findings indicate that bivalirudin is as safe as UFH for these patients, which is crucial for improving treatment options.
Who this helps: This helps doctors and their patients with acute coronary syndrome undergoing PCI.