Does Dr. Seltzer study sleep disorders?

Yes, Dr. Seltzer's research focuses on how sleep patterns affect memory and brain structure, which is directly relevant to sleep disorders.

What types of memory issues are affected by Dr. Seltzer's work?

His findings relate to memory consolidation and are particularly relevant for individuals with stronger fear memories and general memory problems.

Can Dr. Seltzer's findings help in treating memory problems?

His research may lead to better understanding of how sleep affects memory, which could inform future treatment approaches for those with memory difficulties.

PAUL DAVID SELTZER, D.O.

WEST PALM BEACH, FL

Research Active

Orthopaedic Surgery NPI registered 21+ years 1 publication 2020 – 2020 NPI: 1255334348

Orthopaedic Surgery

Mice Circadian Rhythm Neurons Extracellular Matrix Proteins Extracellular Matrix Nerve Net Thalamic Nuclei

Practice Location

2051 45TH ST
WEST PALM BEACH, FL 33407-2028

Phone: (561) 848-0330

What does PAUL SELTZER research?

Dr. Seltzer studies the role of perineuronal nets (PNNs), which are special structures that wrap around neurons (the brain's nerve cells), influencing their activity and memory processes. He investigates how these PNNs change throughout the day and night, particularly during sleep. His research explores the connections between sleep deprivation, memory consolidation, and the structural changes in the brain that can lead to stronger fear memories. This research is significant for individuals experiencing memory problems and sleep disorders, as it could lead to better understanding and potential treatments for these issues.

Key findings

In mice, perineuronal nets were found to decrease during the day and this natural rhythm was altered by sleep deprivation, leading to stronger fear memories.
Human studies indicated similar changes in perineuronal nets in specific brain areas, pointing to a key role in memory consolidation during sleep.
The disruption of PNN patterns due to lack of sleep has potential implications for understanding memory issues in patients.

Frequently asked questions

Does Dr. Seltzer study sleep disorders?: Yes, Dr. Seltzer's research focuses on how sleep patterns affect memory and brain structure, which is directly relevant to sleep disorders.
What types of memory issues are affected by Dr. Seltzer's work?: His findings relate to memory consolidation and are particularly relevant for individuals with stronger fear memories and general memory problems.
Can Dr. Seltzer's findings help in treating memory problems?: His research may lead to better understanding of how sleep affects memory, which could inform future treatment approaches for those with memory difficulties.

Publications in plain English

Circadian Rhythms of Perineuronal Net Composition.

2020

eNeuro

Pantazopoulos H, Gisabella B, Rexrode L, Benefield D, Yildiz E +6 more

Plain English
This study looked at how perineuronal nets (PNNs), which are structures surrounding neurons that help regulate brain activity, change throughout the day and night, particularly during sleep. The researchers found that in mice, PNNs decreased during the day and this rhythm was disrupted when the mice were sleep-deprived, resulting in stronger fear memories. In humans, similar changes in PNNs were observed in certain brain areas, suggesting these patterns are important for memory consolidation during sleep. Who this helps: This helps patients struggling with memory issues and sleep disorders.

PubMed

Frequent Co-Authors

Harry Pantazopoulos Barbara Gisabella Lindsay Rexrode David Benefield Emrah Yildiz Jake Valeri Gabriele Chelini Anna Reich Magdalena Ardelt Sabina Berretta

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.