Practice Location

11900 E 12 MILE RD STE 300
WARREN, MI 48093-3491

Phone: (248) 465-5140

What does PHILIP SHAHEEN research?

Philip J Shaheen studies osteonecrosis, a condition where the blood supply to the femoral head (the ball part of the hip joint) is interrupted, leading to bone death. His research particularly looks at the inflammation in the synovial tissue—the lining of the hip joint—in patients suffering from this condition. He found that many patients exhibited notable inflammation even if they didn’t have any previously diagnosed inflammatory diseases, implying that the inflammation could be a direct consequence of the bone dying instead of an underlying inflammatory condition. This insight suggests new potential targets for treatments focused on managing inflammation in such patients.

Key findings

  • In patients with osteonecrosis of the femoral head, significant inflammation was observed in the synovial tissue.
  • Some patients demonstrated synovial inflammation without prior diagnosis of any inflammatory disease, indicating a novel relationship between bone death and inflammation.
  • The inflammation in synovial tissue was primarily driven by immune cells known as macrophages and T cells.

Frequently asked questions

Does Dr. Shaheen study osteonecrosis?
Yes, Dr. Shaheen specifically researches osteonecrosis and its effects on inflammation in the hip joint.
What is the significance of the inflammation found in Dr. Shaheen's research?
The inflammation may provide potential new targets for treatments aimed at managing osteonecrosis.
Are there any patient groups that could benefit from Dr. Shaheen's work?
Patients suffering from osteonecrosis or hip joint pain due to bone issues could benefit from his findings.

Publications in plain English

Single-Surgeon Experience and Complications of a Fixed-Bearing Total Ankle Arthroplasty.

2018

Foot & ankle international

Pangrazzi GJ, Baker EA, Shaheen PJ, Okeagu CN, Fortin PT

Plain English
This study looked at the experiences of a single surgeon with a specific type of ankle replacement surgery (Total Ankle Arthroplasty, or TAA) using a device called the Tornier Salto Talaris. Among 96 patients, there was a 34% rate of complications, leading to 11 reoperations, including 5 that were complete replacements of the ankle. These results are similar to what has been seen in other studies, which is important because it helps set expectations for patients and surgeons regarding recovery and potential issues with this type of surgery. Who this helps: This benefits patients undergoing ankle replacement surgery and their doctors.

PubMed

Synovial inflammation in patients with osteonecrosis of the femoral head.

2009

Clinical and translational science

Rabquer BJ, Tan GJ, Shaheen PJ, Haines GK, Urquhart AG +1 more

Plain English
Researchers examined the tissue lining the hip joint in patients with a condition where the thighbone dies from lack of blood supply, finding that many of these patients had significant inflammation in that lining tissue. Surprisingly, some patients showed this inflammation without having any diagnosed inflammatory disease, suggesting their hip inflammation was caused by the bone death itself rather than an existing condition. The inflammation was driven primarily by immune cells called macrophages and T cells, which may offer new targets for treatment.

PubMed

Frequent Co-Authors

Garett J Pangrazzi Erin A Baker Phillip J Shaheen Chikezie N Okeagu Paul T Fortin Bradley J Rabquer Giselle J Tan G Kenneth Haines Andrew G Urquhart Alisa E Koch

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.