PHILIP H. SYMES, MD

ERIE, PA

Research Active
Internal Medicine - Medical Oncology NPI registered 21+ years 4 publications 1987 – 2017 NPI: 1033115464
Reproducibility of ResultsCaregiversNeoplasmsQuality of LifeSurveys and QuestionnairesEthnicityCyclic AMPPsychometricsMonocytesFactor Analysis, StatisticalLinguisticsTranslationsAdenylate Cyclase ToxinBordetella pertussisLuminescent Measurements

Practice Location

2508 MYRTLE ST STE 200
ERIE, PA 16502-2700

Phone: (814) 452-7822

What does PHILIP SYMES research?

Dr. Philip H. Symes studies how environmental factors, specifically climate change, affect plant life in Australian botanic gardens, as well as the emotional and psychological challenges faced by caregivers of cancer patients. His research involves planning the future of plant collections to ensure that they can thrive under expected climate conditions by selecting resilient species and using sustainable practices. In addition, he evaluates tools like the CareGiver Oncology Quality of Life questionnaire to better understand and improve the quality of life for caregivers, recognizing their vital role in supporting cancer patients.

Key findings

  • The Royal Botanic Gardens Victoria plans to ensure that by 2036, at least 75% of its 8,500 plant species will thrive in the climate expected in 2090, focusing on sustainable practices.
  • The American version of the CarGOQoL questionnaire was validated with 87 caregivers, showing strong consistency and responsiveness, especially in psychological well-being and social support.
  • Inhibition of immune responses by Bordetella pertussis toxin showed a 96% decrease in the ability of monocytes to generate reactive substances meant to fight infections, revealing important mechanisms of infection.

Frequently asked questions

Does Dr. Symes study climate change?
Yes, he studies the impact of climate change on plant biodiversity, particularly in the Royal Botanic Gardens Victoria.
What support does Dr. Symes provide for cancer caregivers?
He works on validating questionnaires that assess the quality of life for caregivers, helping improve support and resources for them.
Is Dr. Symes's research relevant to infection treatment?
Yes, his work on Bordetella pertussis provides insights into how the bacteria can evade the immune response, which can inform treatment strategies.

Publications in plain English

Adapting the botanical landscape of Melbourne Gardens (Royal Botanic Gardens Victoria) in response to climate change.

2017

Plant diversity

Entwisle TJ, Cole C, Symes P

Plain English
This study looks at how the Royal Botanic Gardens Victoria in Melbourne is planning to change its plant collections in response to climate change. The gardens host 8,500 plant species and receive 1.6 million visitors each year, so the strategy aims to ensure that by 2036, at least 75% of the plants will thrive in the climate expected in 2090. The focus is on selecting new plant species that can survive future climate conditions, improving irrigation systems, and using sustainable water sources, all while maintaining biodiversity. Who this helps: This benefits visitors, conservationists, and future generations.

PubMed

Validation of the American version of the CareGiver Oncology Quality of Life (CarGOQoL) questionnaire.

2016

Health and quality of life outcomes

Kaveney SC, Baumstarck K, Minaya-Flores P, Shannon T, Symes P +2 more

Plain English
Researchers focused on validating an American version of the CareGiver Oncology Quality of Life (CarGOQoL) questionnaire, which helps assess the quality of life of caregivers for cancer patients. They tested this questionnaire on 87 caregivers and found it to be reliable and effective, as most areas of the questionnaire showed strong consistency and responsiveness, with specific aspects like psychological well-being and social support scoring particularly well. This matters because understanding caregivers’ quality of life can lead to better support and resources for them, which ultimately helps improve care for cancer patients. Who this helps: This helps caregivers of cancer patients.

PubMed

Measurement of neutrino oscillations with the MINOS detectors in the NuMI beam.

2008

Physical review letters

Adamson P, Andreopoulos C, Arms KE, Armstrong R, Auty DJ +167 more

Plain English
Researchers studied how muon neutrinos change into different types, known as "neutrino oscillations," using detectors from the MINOS experiment over two years. They found strong evidence for these oscillations, with specific measurements indicating a mass difference of about 0.00243 eV² and a high mixing angle, which supports the idea that neutrinos behave according to quantum physics. This finding rules out two other possible explanations for why neutrinos seemed to disappear during travel, making the results more reliable. Who this helps: This helps scientists studying fundamental particles and could lead to advances in our understanding of the universe.

PubMed

Inhibition of monocyte oxidative responses by Bordetella pertussis adenylate cyclase toxin.

1987

Journal of immunology (Baltimore, Md. : 1950)

Pearson RD, Symes P, Conboy M, Weiss AA, Hewlett EL

Plain English
This study looked at how a toxin produced by the bacteria Bordetella pertussis affects immune cells called monocytes. The researchers found that this toxin significantly reduced the monocytes' ability to generate reactive substances meant to fight off infections, showing a 96% decrease in their response to certain triggers. This is important because it reveals a mechanism by which Bordetella pertussis may weaken the immune response, helping it cause disease without damaging the immune cells themselves. Who this helps: This research benefits doctors and scientists working to understand and treat infections caused by Bordetella pertussis.

PubMed

Frequent Co-Authors

Timothy J Entwisle Chris Cole Sarah C Kaveney Karine Baumstarck Patricia Minaya-Flores Tarrah Shannon Anderson Loundou Pascal Auquier P Adamson C Andreopoulos

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.