DR. REGINALD E. ISHMAN, M.D.

WARSAW, NY

Research Active
Ophthalmology - Ophthalmic Plastic and Reconstructive Surgery NPI registered 21+ years 2 publications 1976 – 1978 NPI: 1710980016
Ophthalmology - Ophthalmic Plastic and Reconstructive Surgery
LiverOxidation-ReductionCattleKineticsBinding SitesNADUridine Diphosphate Glucose DehydrogenaseCarbohydrate DehydrogenasesNicotinic AcidsAlcohol OxidoreductasesDithionitrobenzoic AcidIodoacetamideIodoacetatesUridine Diphosphate GlucoseUridine Diphosphate Xylose

Practice Location

2469 STATE ROUTE 19 N
WARSAW, NY 14569-9336

Phone: (585) 786-2288

What does REGINALD ISHMAN research?

Dr. Ishman's research centers around a key enzyme known as uridine diphosphate glucose dehydrogenase, which plays an important role in sugar metabolism. He studies how different compounds can affect the activity of this enzyme, particularly looking at how a chemical called 6,6-Dithiodinicotinate impacts its function. By examining these effects, Dr. Ishman helps provide insights into enzyme behavior and control, which is valuable for scientists exploring sugar metabolism and potential treatments related to enzymatic activity.

Key findings

  • Using 6,6-Dithiodinicotinate, the activity of the uridine diphosphate glucose dehydrogenase enzyme was reduced by 60%.
  • Another treatment was found to quickly restore the enzyme's function after its activity was inhibited.

Frequently asked questions

Does Dr. Ishman study sugar metabolism?
Yes, Dr. Ishman focuses on enzymes involved in sugar metabolism, particularly in the bovine liver.
What chemical has Dr. Ishman researched?
He has studied the effects of 6,6-Dithiodinicotinate on the activity of specific enzymes.
Is Dr. Ishman's work relevant to researchers studying enzymes?
Yes, his findings are particularly valuable for researchers looking at enzyme function and regulation.

Publications in plain English

Half-sites oxidation of bovine liver uridine diphosphate glucose dehydrogenase.

1978

The Biochemical journal

Franzen JS, Marchetti P, Ishman R, Ashcom J

Plain English
This study looked at how a specific chemical affects an enzyme from bovine liver that helps in processing sugars. Researchers found that when they used a compound called 6,6-Dithiodinicotinate, it reduced the enzyme's activity by 60% but that extra treatment with another chemical quickly restored its function. This research is important because it helps scientists understand how the enzyme works and how its activity can be controlled. Who this helps: This benefits researchers and scientists studying enzyme function and sugar metabolism.

PubMed

Half-of-the-sites reactivity of bovine liver uridine diphosphoglucose dehydrogenase toward iodoacetate and iodoacetamide.

1976

Biochemistry

Franzen JS, Ishman R, Feingold DS

PubMed

Frequent Co-Authors

J S Franzen P Marchetti J Ashcom D S Feingold

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.