Consolidation hemibody radiotherapy following induction combination chemotherapy in high-tumor-burden multiple myeloma.
1992Journal of clinical oncology : official journal of the American Society of Clinical Oncology
MacKenzie MR, Wold H, George C, Gandara D, Ray G +5 more
Plain English
This study looked at a treatment approach for patients with advanced multiple myeloma, a type of blood cancer. Researchers tested giving chemotherapy first for eight cycles, followed by hemibody radiation therapy and more chemotherapy. Out of 72 patients, 22 had a complete recovery after the initial treatment, and the overall survival time was about 134 weeks, which was similar to other treatments. This matters because it shows that while the treatment was safe and could be done in community healthcare settings, it didn't lead to longer survival compared to existing options.
Who this helps: This helps patients with high-tumor-burden multiple myeloma and their doctors.