ROBERT T. TERRY, MD

BILLINGS, MT

Research Active
Internal Medicine - Interventional Cardiology NPI registered 21+ years 49 publications 2020 – 2025 NPI: 1588669071
MiceReproducibility of ResultsPregnancyMental HealthQuality of LifeSurveys and QuestionnairesQualitative ResearchAttitude of Health PersonnelSocial SupportLearningEnglandMidwiferyBehavioral Risk Factor Surveillance SystemKidney CalculiCalcium Oxalate

Practice Location

2900 12TH AVE N
BILLINGS, MT 59101-7502

Phone: (406) 237-5001

What does ROBERT TERRY research?

Dr. Terry's research spans multiple health conditions and treatments, focusing on how complex interactions affect patient outcomes. He explores issues like the rare complication of syringomyelia linked to TB meningitis, which can severely impact mobility and require extensive medical care. He also investigates the importance of social support for adults with serious mental illnesses, highlighting how strong relationships can enhance community engagement and overall well-being. Furthermore, Dr. Terry delves into the effectiveness of pelvic floor exercises led by midwives for new mothers to reduce urinary incontinence after childbirth. His studies support improving healthcare practices through better training and patient support systems.

Key findings

  • In a case study, a 30-year-old man developed syringomyelia due to TB meningitis, leading to significant complications and paralysis, underscoring the serious neurological risks involved.
  • In his study on pelvic floor exercises, 65% of women trained by midwives learned the exercises, compared to only 38% in the standard care group, and reported fewer urinary issues (44% vs. 54%).
  • The research on kidney stones found that patients who took medical treatments had a recurrence rate of 21.3%, compared to 37.5% for those who did not, showing the effectiveness of proper medication over time.

Frequently asked questions

Does Dr. Terry study complications from TB meningitis?
Yes, he has researched the rare neurological complication of syringomyelia that can occur in patients with TB meningitis.
What treatments has Dr. Terry researched for urinary incontinence?
He studied the impact of pelvic floor muscle exercises taught by midwives on reducing urinary incontinence in new mothers.
Is Dr. Terry's work relevant to patients facing kidney stones?
Yes, his research shows that specific medical treatments can significantly reduce the recurrence rates of kidney stones in patients.
What role does social support play in mental health according to Dr. Terry?
His research indicates that strong social support from friends and family enhances community participation for adults with serious mental illnesses.
How does Dr. Terry's research help medical students?
His studies highlight the importance of social connections for medical students, particularly those from diverse backgrounds, to support their learning and well-being.

Publications in plain English

Antenatal pelvic floor muscle exercise intervention led by midwives in England to reduce postnatal urinary incontinence: APPEAL feasibility and pilot randomised controlled cluster trial.

2025

BMJ open

MacArthur C, Bick D, Salmon V, Jones E, Hay-Smith J +11 more

Plain English
This study looked at whether training midwives to teach pregnant women pelvic floor muscle exercises (PFME) could help reduce urinary incontinence after childbirth. It found that 65% of women in the trained groups learned how to do the exercises, compared to only 38% in the standard care group. Additionally, only 44% of the women in the trained group reported having urinary issues, compared to 54% in the control group, suggesting the training makes a difference. Who this helps: This benefits new mothers who may face urinary incontinence after giving birth.

PubMed

The challenges faced by early-career international medical graduates in general practice and the opportunities for support: a mixed methods study.

2025

Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors

Jager A, Terry R, Harris M

Plain English
This study focused on the challenges faced by early-career international doctors working as general practitioners (GPs) in South West England. Researchers found that out of 29 survey responses and 9 interviews, many IMG GPs struggle with issues like language barriers, racism, feelings of exclusion, and difficulty adapting to their new environment. Additionally, even though some seek help, most believe the support offered is inadequate, which is critical since improving these circumstances is essential for keeping these doctors in the workforce and ensuring better patient care. Who this helps: This benefits international medical graduates, the healthcare system, and ultimately patients who rely on their care.

PubMed

Early career midwives' experiences of development opportunities and their relation to retention and job satisfaction: an interpretative phenomenological analysis study.

2025

BMC pregnancy and childbirth

Terry R, Spendlove Z

Plain English
This study focused on the experiences of early career midwives in the UK regarding their opportunities for professional development. Researchers found that many of these midwives felt there were few chances for growth, which negatively impacted their job satisfaction and career advancement. Specifically, factors like limited awareness and access to development opportunities, along with relationships with their managers, played a significant role in their experiences. Addressing these development needs could help retain skilled midwives and improve care for patients. Who this helps: This research benefits midwives and ultimately the families they care for during childbirth.

PubMed

A systematic review of how endocrine-disrupting contaminants are sampled in environmental compartments: wildlife impacts are overshadowed by environmental surveillance.

2025

Environmental science and pollution research international

Simms A, Robert K, Spencer RJ, Treby S, Williams-Kelly K +5 more

Plain English
This study looked at how environmental samples are collected to measure harmful chemicals called endocrine-disrupting contaminants (EDCs), which can impact both wildlife and humans. Researchers reviewed over 9,000 papers and found that most EDC research focuses on water samples, which were studied in 50-75% of cases, while wildlife samples were included in only about 30% of studies. This matters because understanding how EDCs affect animals is crucial, yet much of the research overlooks these important connections between environmental contamination and wildlife health. Who this helps: This helps wildlife conservationists and environmental scientists.

PubMed

Yb:LuOsingle-crystal fiber: spectroscopy, amplification, and lasing.

2025

Optics letters

Topper B, Benton A, Terry R, Pettes M, Ballato J +2 more

Plain English
This study focused on a new type of laser made from lutetium oxide single-crystal fibers. Researchers successfully created lasers that produced a maximum output of about 300 milliwatts at a specific wavelength of 1033 nanometers. These findings are significant because they show that lutetium oxide has the potential for advanced laser technologies, which could lead to more powerful and efficient lasers in the future. Who this helps: Patients and doctors who rely on advanced laser technologies for medical treatments.

PubMed

MIKROBE: a feasibility study for a randomised controlled trial of one-stage or two-stage surgery for prosthetic knee infection.

2025

Pilot and feasibility studies

Terry R, Dean S, Hourigan P, Waterson HB, Wylde V +7 more

Plain English
This study looked at whether one-stage or two-stage surgery is better for treating infections in knee replacements. Out of 136 screened patients, only 3 actually participated in the study, showing that it's challenging to organize a larger trial to compare the two surgery methods. This matters because better understanding the best treatment option could improve recovery for many patients with knee replacement infections. Who this helps: This helps patients with knee replacements who may develop infections.

PubMed

Exploring the influence of social support on community participation for adults with serious mental illnesses.

2025

American journal of community psychology

Terry R, Leickly E, Townley G

Plain English
This study looked at how support from friends, family, and other natural relationships affects participation in community activities for adults with serious mental illnesses. It found that stronger overall support was linked to more involvement in the community, with family and friends being the most common sources of support, while spouses and pets provided the most emotional support. Understanding these connections is important because enhancing social support can lead to greater community engagement for those facing mental health challenges. Who this helps: This benefits adults with serious mental illnesses and their families.

PubMed

Influence of Gallium Focused Ion Beam on Polyethylene: Study of Molecular Damage.

2025

Microscopy research and technique

Paśniewski M, Poleunis C, Delcorte A, Terry R, Abmayr DW +2 more

Plain English
This study looked at how a technique called gallium focused ion beam (FIB) affects the structure of a plastic called polyethylene. Researchers found that using this method can significantly damage the plastic, particularly by changing its molecular structure and causing a loss of hydrogen in the material, with the most damage occurring at certain depths below the surface. This matters because it raises concerns about using FIB for preparing samples when the surface properties are crucial for analysis. Who this helps: This helps researchers and companies that rely on precise material analysis, especially those working with plastics.

PubMed

Early-Onset Syringomyelia: A Rare Complication of TB Meningitis.

2025

Cureus

Adhikarla AK, Terry R, Ghrew M, Mohanraj R

Plain English
This study looked at a rare condition called syringomyelia that can develop in patients with TB meningitis, specifically when spinal fluid movement is disrupted. A 30-year-old man who traveled to a TB-affected area became seriously ill within a week, showing severe symptoms like loss of movement and difficulty walking. He was diagnosed with syringomyelia affecting parts of his spinal cord, which led to paralysis; despite treatment, he faced significant complications and required extensive medical care. Who this helps: This information is crucial for doctors treating patients with TB meningitis, as it highlights the risk of developing serious neurological complications.

PubMed

The assessment of physiotherapy practice is a robust measure of entry-level physiotherapy standards: Reliability and validity evidence from a large, representative sample.

2025

PloS one

Reubenson A, Ng L, Lawton V, Nahon I, Terry R +25 more

Plain English
This study looked at a tool called the Assessment of Physiotherapy Practice (APP), which measures how well new physiotherapy graduates perform in both professional and clinical areas. Researchers analyzed nearly 9,000 assessments from 1,865 students across 19 universities in Australia and New Zealand and found that the tool works best when evaluating performance based on two main factors: professional skills and clinical skills. This is important because ensuring students are competent in both areas helps maintain high standards for new physiotherapists entering the workforce. Who this helps: This benefits students, educators, and ultimately patients who rely on skilled physiotherapists.

PubMed

Disparities in preconception health indicators in U.S. women: a cross-sectional analysis of the behavioral risk factor surveillance system 2019.

2024

Journal of perinatal medicine

Terry R, Gatewood A, Elenwo C, Long A, Wu W +3 more

Plain English
This study looked at the health of women in the U.S. who want to become pregnant but aren't using birth control. It found significant differences based on factors like age, race, education, and income. For example, women with lower incomes and less education had higher rates of obesity and depression and were less likely to have health insurance or a primary care doctor. Understanding these disparities is important because it can help improve services and support for women before they become pregnant, ultimately leading to better health outcomes for mothers and babies. Who this helps: This helps women planning pregnancies and healthcare providers working to improve maternal health.

PubMed

MicroSegNet: A deep learning approach for prostate segmentation on micro-ultrasound images.

2024

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society

Jiang H, Imran M, Muralidharan P, Patel A, Pensa J +10 more

Plain English
This study developed a new tool called MicroSegNet, which uses advanced computer algorithms to improve the accuracy of identifying the prostate in high-resolution micro-ultrasound images. The tool performed impressively, achieving a Dice coefficient of 0.939, meaning it matched expert annotations closely, and it did better than existing methods and even human experts. This improvement is important because it can lead to more precise measurements and better diagnoses for prostate cancer, helping doctors plan treatments more effectively. Who this helps: This benefits patients at risk for prostate cancer by improving diagnosis and treatment accuracy.

PubMed

Social connections and social identity as a basis for learning and support: Experiences of medical students with minoritised and non-minoritised ethnic identities.

2024

Medical education

Bull S, Terry R, Rice N, Carrieri D, Tarrant M +1 more

Plain English
This study looked at how medical students form social connections based on their ethnic backgrounds and how these relationships affect their learning and well-being. Researchers found that students generally connect with three to four peers, with 71.9% feeling a strong sense of belonging in these groups, regardless of whether they were from minoritised or non-minoritised ethnic backgrounds. These connections help students manage the stress of medical school and improve their academic success, highlighting the importance of creating supportive learning environments. Who this helps: This helps medical students, particularly those from minoritised backgrounds, by fostering a supportive community for their education.

PubMed

Pharmacotherapy and Stone Mineral Subtype Influence Long-Term Recurrence Rates in Calcium Stone Formers.

2024

Kidney360

Ruchi R, Di Valerio EA, Bozorgmehri S, Bacchus MW, Canales BK +3 more

Plain English
This study looked at how different treatments can affect the chance of kidney stones coming back in people who have had certain types of calcium stones for a long time. Researchers followed 149 patients for about 10.6 years and found that those who took medical treatments (like specific medications) had fewer stone occurrences—21.3% compared to 37.5% for those who did not take the treatments. This research is important because it shows that using the right medications can significantly reduce the risk of kidney stones over time, although the benefits may take up to five years to show. Who this helps: Patients at risk of recurrent kidney stones.

PubMed

Flu-Phobia: Influenza Vaccine Hesitancy in a Rural Primary Care Setting.

2024

Cureus

Lavertue SM, Terry R, Muggleton R

Plain English
This study looked at why people in a rural area of New York are hesitant to get the flu vaccine. Researchers found that over 50% of the patients decided not to get the flu shot this year, but only a small number of them connected their choice to the controversies surrounding the COVID-19 vaccine. Understanding these attitudes is important because it can help doctors create better strategies to encourage flu vaccinations in the future. Who this helps: This helps patients and doctors in rural communities.

PubMed

Infrastructure, capabilities, and capacities required for clinical trials design and delivery: A rapid scoping review of recommendations and regulations.

2024

Wellcome open research

Merson L, Witt K, Hussaini A, Siddiqui A, Harriss E +9 more

Plain English
This research examined what is needed to effectively design and conduct clinical trials according to global standards. It found that specific infrastructure, skills, and resources must be developed to ensure high-quality trials, with a focus on guidelines from the World Health Assembly. The findings will help create a framework for assessing and improving the systems that support clinical research. Who this helps: This benefits researchers, healthcare providers, and patients involved in clinical trials.

PubMed

An Investigation into Equine Nutrition Knowledge and Educational Needs of Equine Veterinarians.

2023

Journal of veterinary medical education

Nichols JL, Robinson JS, Hiney KM, Terry R, Ramsey JW

Plain English
This study looked into how well veterinarians who mainly work with horses understand horse nutrition and what educational support they need. The results showed that only 21% of these veterinarians felt confident in their nutrition knowledge after finishing school, and although most provided nutritional advice, 75% had not taken any further education in the last year. The findings highlight a need for better training in specific nutrition topics, such as managing conditions like insulin resistance and metabolic syndrome, to improve horse care. Who this helps: This helps veterinarians and their horse-owning clients.

PubMed

A systematic review and thematic synthesis of qualitative literature on personal recovery and voice hearing.

2023

Clinical psychology & psychotherapy

Hall B, Terry R, Hayward M

Plain English
This study reviewed existing research on how people with psychosis experience recovery from hearing voices. It analyzed twelve studies and found that recovery has different stages, involves both support and challenges, and requires people to shift from seeing their voices as distressing to integrating them into their lives. Understanding these recovery processes is crucial because it can help improve the support services offered to individuals who hear voices. Who this helps: This benefits patients experiencing voice hearing and the professionals who support them.

PubMed

To the Editor: COMLEX-USA vs USMLE? Irrelevant.

2023

Journal of graduate medical education

Terry R, Lavertue S

PubMed

Trends and forecasted rates of adverse childhood experiences among adults in the United States: an analysis of the Behavioral Risk Factor Surveillance System.

2023

Journal of osteopathic medicine

Hartwell M, Hendrix-Dicken A, Terry R, Schiffmacher S, Conway L +1 more

Plain English
This study looked at the experiences of adults in the U.S. who had difficult childhoods, known as adverse childhood experiences (ACEs). Researchers found that the average number of ACEs has increased, with adults born in 1998 reporting an average of 2.74 ACEs, compared to just 0.79 for those born before 1940. This matters because higher ACE scores are linked to worse health outcomes, highlighting the urgent need for prevention programs to help children avoid these negative experiences. Who this helps: This benefits children, parents, and healthcare providers focused on improving child welfare and mental health.

PubMed

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.

2023

Genome medicine

Mayoh C, Gifford AJ, Terry R, Lau LMS, Wong M +39 more

Plain English
This study focused on understanding the immune environment of high-risk childhood cancers to improve immunotherapy options. Researchers discovered a new 15-gene "Immune Paediatric Signature Score" (IPASS) that shows over 31% of these cancers have T-cells present, indicating potential targets for treatment. The findings reveal that traditional biomarkers often used in adults, like PD-L1 expression, don't predict T-cell infiltration in children’s cancers, highlighting the need for personalized approaches for effective treatments. Who this helps: This research benefits children with high-risk cancers and their doctors by providing better ways to tailor immunotherapy treatments.

PubMed

Disparities in osteoarthritis diagnosis and symptoms between English- and Spanish-speaking Latinas over 40 years of age in the United States: a analysis of the Behavioral Risk Factor Surveillance System.

2023

Ethnicity & health

Dutcher A, Chinthalapally H, Terry R, Balcerak G, Guevara C +2 more

Plain English
This study looked at differences in osteoarthritis diagnosis and symptoms between English- and Spanish-speaking Latinas over 40 years old in the United States. It found that while both groups had similar rates of arthritis diagnosis, Spanish-speaking Latinas aged 65 and older were 55% more likely to report limitations due to pain, and they reported higher pain levels overall. This matters because it highlights the need for better support and resources for Spanish-speaking Latinas dealing with arthritis. Who this helps: This helps Spanish-speaking Latina patients dealing with arthritis.

PubMed

A Comparison of Surgical Subspecialty Match Rates in 2022 in the United States.

2023

Cureus

Lavertue SM, Terry R

Plain English
This study looked at how medical graduates were placed into specialized surgical training programs in 2022 in the U.S., comparing MDs (allopathic graduates) and DOs (osteopathic graduates). It found that MDs had higher match rates than DOs, but the reasons behind this difference are complex and not fully understood. This is important because understanding these match rate disparities can help improve opportunities for all types of medical graduates in competitive specialties. Who this helps: This helps medical students, especially those training as DOs, by providing insights into enhancing their chances in the match process.

PubMed

The challenges faced by early career international medical graduates in general practice and opportunities for supporting them: a rapid review.

2023

BJGP open

Jager A, Harris M, Terry R

Plain English
This study looked at the specific challenges faced by early career international medical graduates (IMGs) working as general practitioners (GPs) in the UK. Researchers found that these GPs encounter seven main challenges, including psychological and social issues, and noted that the support currently provided by the NHS may not be sufficient. This matters because better understanding and addressing these challenges could help ensure a stable workforce of GPs to meet the needs of an aging population. Who this helps: This helps international medical graduates, healthcare managers, and ultimately patients relying on general practice services.

PubMed

A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.

2022

Molecular therapy : the journal of the American Society of Gene Therapy

Maruggi G, Mallett CP, Westerbeck JW, Chen T, Lofano G +31 more

Plain English
This research focused on a new type of mRNA vaccine for COVID-19, designed to provide strong and lasting immunity. In tests with mice and hamsters, a two-dose version of the vaccine generated a strong immune response, effectively neutralizing the original virus and variants like Alpha, Beta, and Delta. It also showed no major safety concerns and significantly lowered viral levels in the hamsters’ airways, indicating it could protect against COVID-19 disease. Who this helps: This benefits patients, especially those at risk for severe COVID-19 and healthcare providers managing the virus.

PubMed

Inconsistent Country-Wide Reporting of Adverse Drug Reactions to Antimicrobials in Sierra Leone (2017-2021): A Wake-Up Call to Improve Reporting.

2022

International journal of environmental research and public health

Thomas F, Abiri OT, Komeh JP, Conteh TA, Bah AJ +5 more

Plain English
This study looked at how adverse drug reactions (ADRs) to antimicrobial medications were reported in Sierra Leone from 2017 to 2021. It found that out of 566 reports, most were about antiparasitics and there were serious delays in reporting, with 90% of reports taking over 30 days to be logged. The results show that patients experienced various outcomes, with almost 60% recovering and only a small fraction resulting in death. Who this helps: This helps patients and healthcare providers by highlighting the need for better and faster reporting of drug reactions to ensure safety.

PubMed

Impaired Arithmetic Fact Retrieval in an Adult with Developmental Dyscalculia: Evidence from Behavioral and Functional Brain Imaging Data.

2022

Brain sciences

Göbel SM, Terry R, Klein E, Hymers M, Kaufmann L

Plain English
This study looked at a 19-year-old student with developmental dyscalculia (DD), a condition that makes it difficult for people to do math. The researchers compared her ability to multiply and subtract to those of 18 peers without DD. They found that she struggled significantly with multiplication but not with subtraction, showing different brain activity patterns related to these math processes. This matters because it highlights that people with DD may have distinct challenges with different types of math, which can influence the way they are taught. Who this helps: This study helps patients with developmental dyscalculia and their educators.

PubMed

Benchtop Evaluation of Miniature Percutaneous Nephrolithotomy Lithotrites.

2022

Journal of endourology

Tabib C, Whelan P, Kim C, Dionise Z, Soto-Palou F +4 more

Plain English
This study looked at different tools used to break up kidney stones during a surgery called mini-percutaneous nephrolithotomy (mPCNL). Researchers tested four devices and found that the 1.9 mm Trilogy probe worked best, clearing stones at a rate of 11.69 mg per second, which was significantly faster than the other tools tested, like the ShockPulse at 6.29 mg per second and the laser at 4.73 mg per second. This matters because quicker stone removal can reduce surgery time and improve patient recovery. Who this helps: Patients with larger kidney stones who need treatment.

PubMed

COVID-19 Vaccine Hesitancy in a Rural Primary Care Setting.

2022

Cureus

Terry R, Asrar A, Lavertue S

Plain English
This study looked at why some people in rural Chemung County, NY, are hesitant to get the COVID-19 vaccine. Researchers found that many of these individuals have strong political beliefs that influence their decision, making them less likely to get vaccinated. Understanding these barriers is important because it can help improve efforts to encourage more people to get vaccinated, ultimately protecting community health. Who this helps: This benefits patients and public health officials working to increase vaccination rates.

PubMed

Computed tomographic arthrography, gross anatomy and histology demonstrate a communication between synovial invaginations in the proximal aspect of the third interosseous muscle and the carpometacarpal joint in horses.

2022

Frontiers in veterinary science

Gerdes C, Morgan R, Terry R, Foote A, Smith R

Plain English
This study looked at the relationship between a specific muscle in horses, called the third interosseous muscle or suspensory ligament, and a joint in their front legs. Researchers found that this muscle is directly connected to the joint, with 100% of the examined limbs showing this link through imaging techniques. This is important because it helps veterinarians understand how local anesthesia might affect both the joint and the ligament during treatments. Who this helps: This benefits veterinarians treating horses, particularly when diagnosing or injecting medicine into the carpal area.

PubMed

Correction: Standardized and reproducible measurement of decision-making in mice.

2022

eLife

, Aguillon V, Angelaki DE, Bayer H, Bonacchi N +33 more

PubMed

Advances in CAR T cell immunotherapy for paediatric brain tumours.

2022

Frontiers in oncology

Rao P, Furst L, Meyran D, Mayoh C, Neeson PJ +4 more

Plain English
This research paper focuses on new treatments for brain tumors in children, which are the most common type of solid tumor in kids and the leading cause of cancer deaths in this age group. It highlights recent developments in a type of treatment called CAR T cell immunotherapy, which uses modified immune cells to fight cancer. The study discusses various targets for this therapy and ways to make it more effective, aiming to provide better outcomes and reduce long-term disabilities for young patients. Who this helps: This benefits children with brain tumors and their families.

PubMed

Large-scale migration into Britain during the Middle to Late Bronze Age.

2022

Nature

Patterson N, Isakov M, Booth T, Büster L, Fischer CE +218 more

Plain English
Researchers studied the genetic ancestry of people in England and Wales from the Bronze Age to better understand how early European farmers influenced their ancestry. They found that between 1000 and 875 BC, these early farmers contributed about half of the ancestry of people in southern Britain, while this was not the case in northern Britain. This migration is important because it likely played a role in the spread of early Celtic languages in the region. Who this helps: This helps historians, archaeologists, and geneticists understand the cultural and linguistic development in Britain.

PubMed

Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-Scattering Fiber Diffuser.

2021

IEEE transactions on medical imaging

Li M, Vu T, Sankin G, Winship B, Boydston K +3 more

Plain English
This study focused on improving a type of medical imaging called photoacoustic tomography, which uses light to create images of tissues inside the body. The researchers developed a new type of light diffuser that costs less to make and provides consistent light distribution, allowing the imaging process to reach deeper areas of tissue—up to about 10 centimeters deep in tests. This advancement is important because it could enable doctors to image difficult-to-reach parts of the body more effectively, improving diagnosis and treatment strategies. Who this helps: This helps patients needing deeper tissue imaging, particularly for conditions affecting organs like the kidneys.

PubMed

Development of a small molecule that corrects misfolding and increases secretion of Z α-antitrypsin.

2021

EMBO molecular medicine

Lomas DA, Irving JA, Arico-Muendel C, Belyanskaya S, Brewster A +32 more

Plain English
Researchers developed a new small molecule aimed at treating severe α-antitrypsin deficiency caused by a specific genetic mutation. They found that this compound, when tested in lab models, increased the secretion of a key protein called Z α-antitrypsin by three times in cell cultures and by seven times in mice, although it did not reduce liver damage. This finding is important because it shows that small molecules can potentially correct problems caused by genetic mutations, paving the way for new treatments for patients with this condition. Who this helps: Patients with severe α-antitrypsin deficiency.

PubMed

Multimodal imaging of drug and excipients in rat lungs following an inhaled administration of controlled-release drug laden PLGA microparticles.

2021

The Analyst

Robinson E, Giffen P, Hassall D, Ball D, Reid H +9 more

Plain English
This study looked at how well tiny drug-filled particles used in inhalers distribute in the lungs of rats after being inhaled. The researchers found that after giving a single dose, the drugs were still detected in the lungs at various times, showing that these particles can effectively release medication over time. This is important because it could lead to less frequent dosing and fewer side effects for patients using inhaled medications for respiratory issues. Who this helps: This benefits patients with respiratory illnesses and their doctors.

PubMed

Antibiotic Use in Broiler Poultry Farms in Kathmandu Valley of Nepal: Which Antibiotics and Why?

2021

Tropical medicine and infectious disease

Koirala A, Bhandari P, Shewade HD, Tao W, Thapa B +3 more

Plain English
This study looked at how antibiotics are used in chicken farms in the Kathmandu Valley of Nepal. It found that 90% of the 30 farms surveyed used antibiotics, with the most common being tylosin and colistin. This is concerning because these antibiotics are important for treating human infections, and their use in animals can lead to antibiotic resistance, which poses a risk to public health. Who this helps: This information benefits public health officials and consumers concerned about antibiotic resistance.

PubMed

Guidance for ensuring fair and ethical broad consent for future use. A scoping review protocol.

2021

F1000Research

Maxwell L, Gilyan R, Chavan SA, Merson L, Saxena A +1 more

Plain English
This research paper focuses on how to manage consent for reusing data and samples from medical studies. The study found that while sharing this information can speed up research and improve trust with participants, it also involves risks like privacy concerns. The authors intend to create clear guidelines to help researchers implement broad consent fairly and ethically. Who this helps: This benefits researchers, patients, and communities involved in medical studies.

PubMed

Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.

2021

Clinical cancer research : an official journal of the American Association for Cancer Research

Xiao L, Somers K, Murray J, Pandher R, Karsa M +33 more

Plain English
This study explored a new treatment approach for high-risk neuroblastoma, a type of childhood cancer, by combining two drugs: CBL0137 and panobinostat. The researchers found that this combination significantly slowed tumor growth and even fully eliminated tumors in some cases, particularly in a specific animal model. This is important because it shows that this combined treatment could improve outcomes for children with aggressive neuroblastoma and may work well with other immune-based therapies. Who this helps: This helps patients with high-risk neuroblastoma, particularly children.

PubMed

Standardized and reproducible measurement of decision-making in mice.

2021

eLife

, Aguillon-Rodriguez V, Angelaki D, Bayer H, Bonacchi N +33 more

Plain English
This study examined how mice make decisions and whether these behaviors could be measured consistently in different laboratories. The researchers trained 140 mice in seven labs across three countries, gathering 5 million data points, and found that while learning speed varied, the decision-making behaviors were similar across all settings. This matters because it establishes a standard method for studying mouse behavior, helping ensure that results can be reliably compared and shared in neuroscience research. Who this helps: This benefits scientists studying brain function and decision-making.

PubMed

Evaluation of miRNA as Biomarkers of Emotional Valence in Pigs.

2021

Animals : an open access journal from MDPI

Marsh L, Hutchinson MR, McLaughlan C, Musolino ST, Hebart ML +4 more

Plain English
This study looked at whether certain molecules called miRNAs in pigs could be used to measure their emotions, specifically to tell if they were feeling good or bad. The researchers found that pigs kept in nicer, more stimulating environments had higher levels of dopamine, a chemical associated with positive feelings, compared to those in less stimulating environments. However, miRNAs themselves didn't show any significant changes, indicating they might not be a reliable way to measure emotions in pigs under the conditions tested. Who this helps: This helps animal welfare researchers and farmers understand how to better assess pig emotions and improve their living conditions.

PubMed

Association between nuclear grade of renal cell carcinoma and the aorta-lesion-attenuation-difference.

2021

Abdominal radiology (New York)

Grajo JR, Batra NV, Bozorgmehri S, Magnelli LL, O'Malley P +3 more

Plain English
This study looked at how the nuclear grade of kidney tumors, specifically renal cell carcinoma (RCC), relates to a measurement taken from preoperative CT scans called the aorta-lesion-attenuation-difference (ALAD). They found that while ALAD can help distinguish between low-grade and high-grade tumors, it was not very effective overall, showing a sensitivity of just 32% and an accuracy score of 0.60, which indicates limited usefulness in clinical settings. Understanding this relationship matters because it may help doctors better assess tumor severity before surgery, potentially influencing treatment plans. Who this helps: Doctors and patients undergoing treatment for renal cell carcinoma.

PubMed

Benefits of developing graduate medical education programs in community health systems.

2021

Journal of community hospital internal medicine perspectives

Alweis R, Donato A, Terry R, Goodermote C, Qadri F +1 more

Plain English
This research examined how establishing graduate medical education programs in community and rural health systems can benefit both patients and healthcare providers. It found that these programs can help lower healthcare costs and improve patient outcomes by bringing in trained medical residents and students who can address staffing shortages and provide care during emergencies. Overall, investing in these education programs leads to better health services and prepares the next generation of doctors. Who this helps: This helps patients in community and rural areas who need better access to medical care.

PubMed

Synthetic Olfactory Agonist Use in the Farrowing House to Reduce Sow Distress and Improve Piglet Survival.

2021

Animals : an open access journal from MDPI

Terry R, Nowland TL, van Wettere WHEJ, Plush KJ

Plain English
This study looked at whether a synthetic smell compound could reduce stress in mother pigs (sows) during childbirth and improve the survival of their piglets. Researchers tested this on 47 sows in one study and 418 sows in another. They found that while the new smell did not change stress levels or improve piglet survival, it did slightly reduce the time first-time mother pigs took to give birth. Who this helps: This research is valuable for farmers and veterinarians working with pigs.

PubMed

A Public Health Research Agenda for Managing Infodemics: Methods and Results of the First WHO Infodemiology Conference.

2021

JMIR infodemiology

Calleja N, AbdAllah A, Abad N, Ahmed N, Albarracin D +67 more

Plain English
Researchers examined how to manage the overwhelming and often misleading information (infodemics) that spreads during public health crises, like the COVID-19 pandemic. They hosted the first global infodemiology conference with 110 experts from over 35 countries, resulting in 166 research questions aimed at improving infodemic responses. This is important because better management of infodemics can help protect public health and restore trust in health authorities during emergencies. Who this helps: This benefits public health officials and communities during health crises.

PubMed

After the Study Ends: A Qualitative Study of Factors Influencing Intervention Sustainability.

2020

Professional psychology, research and practice

Bearman SK, Bailin A, Terry R, Weisz JR

Plain English
This study looked at how community clinicians keep using a mental health intervention for young people after initial training and support has ended. All 13 clinicians interviewed reported they were still using the intervention, and they highlighted that adapting the program, previous training, and support from the creators of the intervention were key to their continued use. However, they also faced barriers related to their organization and clients, which need to be addressed for better long-term success. Who this helps: This benefits mental health professionals and the youth they serve by improving the sustainability of effective treatment practices.

PubMed

How LGBT+ scientists would like to be included and welcomed in STEM workplaces.

2020

Nature

Powell K, Terry R, Chen S

PubMed

Adding web-based behavioural support to exercise referral schemes for inactive adults with chronic health conditions: the e-coachER RCT.

2020

Health technology assessment (Winchester, England)

Taylor AH, Taylor RS, Ingram WM, Anokye N, Dean S +22 more

Plain English
This study looked at whether adding an online support program, called e-coachER, to regular exercise referral programs could help inactive adults with chronic health issues be more active over the course of a year. The results showed that those who used e-coachER increased their moderate to vigorous physical activity by only about 11.8 minutes per week compared to the control group, and there was little difference in overall health outcomes or attendance in exercise programs. However, the e-coachER support led to better confidence and a slight increase in quality-adjusted life years despite incurring additional costs. Who this helps: This benefits patients with chronic health conditions who are trying to become more active.

PubMed

Development and Field Validation of Lidocaine-Loaded Castration Bands for Bovine Pain Mitigation.

2020

Animals : an open access journal from MDPI

Saville JW, Ross JA, Trefz T, Schatz C, Matheson-Bird H +7 more

Plain English
This study looked at a new type of castration band for cattle that contains lidocaine, a local anesthetic, to help reduce pain during the procedure. The bands were found to release lidocaine effectively, providing pain relief for at least seven days, and performed better than regular lidocaine injections for long-term pain management. This matters because it can make the castration process less painful for calves and also save farmers time and money by reducing the need for injections or surgery. Who this helps: This helps cattle farmers and the calves undergoing the procedure.

PubMed

Frequent Co-Authors

Sarah Dean Micah Hartwell Chelsea Mayoh Alexandra Jager Michael Harris Laura Merson Samantha M Lavertue Shahab Bozorgmehri John Michael DiBianco

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.