Reexposure to heparin of patients with heparin-associated antibodies.
1989Journal of vascular surgery
Laster J, Elfrink R, Silver D
Plain English
This study looked at the effects of giving heparin to patients who had previously developed antibodies against it, which can cause dangerous blood clots. Out of four patients who received heparin without any medication to prevent complications, three experienced serious issues, including blood clots. In contrast, nine patients who were given aspirin or dipyridamole before receiving heparin during various surgeries had a drop in their platelet counts but did not suffer any major complications.
Who this helps: This research is valuable for patients with a history of heparin reactions and their doctors.