Failure of fresh-frozen radial head allografts in the treatment of Essex-Lopresti injury. A report of four cases.
2005The Journal of bone and joint surgery. American volume
Karlstad R, Morrey BF, Cooney WP
PubMedDR. RYAN RICHARD KARLSTAD, MD
OAK PARK HEIGHTS, MN
Orthopaedic Surgery - Hand Surgery NPI registered 21+ years 2 publications 1994 – 2005 NPI: 1205832896
RadiographyRange of Motion, ArticularTransplantation, HomologousAccidents, TrafficElbow JointRadius FracturesAdministration, TopicalAccidental FallsCorneaRadiusCollagenFluorescent Antibody TechniqueTreatment FailureCorneal InjuriesEye Injuries
What does RYAN KARLSTAD research?
Dr. Karlstad studies how certain treatments can enhance the healing of the eye, specifically the cornea, which is crucial for vision. One of his main interests is a protein called platelet-derived growth factor (PDGF), which is applied directly to the eye to boost wound recovery. This research is particularly relevant for patients recovering from eye surgeries, where strong and quick healing is crucial to prevent complications and reduce the need for additional medical interventions.
Key findings
- Wounds treated with PDGF could withstand 360 mm Hg of pressure compared to 210 mm Hg in untreated wounds seven days after injury.
- After 17 days, PDGF-treated wounds could withstand 1042 mm Hg versus 707 mm Hg in untreated rabbits.
- The use of PDGF leads to a faster and stronger healing process, potentially reducing complications in eye surgery patients.
Frequently asked questions
- Does Dr. Karlstad study eye healing treatments?
- Yes, he focuses on how treatments like platelet-derived growth factor can improve healing in the cornea after injuries or surgeries.
- What is platelet-derived growth factor (PDGF)?
- PDGF is a protein that helps cells grow and repair tissues. In Dr. Karlstad's research, it is used to enhance the healing strength of corneal wounds.
- How does this research help patients?
- This research helps patients by providing treatments that lead to quicker and stronger healing of the eye, reducing the chances of complications after surgery.
Publications in plain English
Effect of topically administered platelet-derived growth factor on corneal wound strength.
1994Current eye research
Murali S, Hardten DR, DeMartelaere S, Olevsky OM, Mindrup EA +4 more
Plain English
This study looked at how a treatment called platelet-derived growth factor (PDGF) affects the strength of healing wounds in the cornea, which is the clear front part of the eye. In tests with rabbits, the results showed that the PDGF-treated wounds could withstand significantly more pressure before breaking apart—360 mm Hg compared to 210 mm Hg in untreated rabbits seven days after injury, and 1042 mm Hg versus 707 mm Hg in another model after 17 days. This is important because faster and stronger healing could lead to fewer complications and less need for stitches in eye surgeries.
Who this helps: This helps patients undergoing eye surgery and their doctors.
Frequent Co-Authors
Bernard F Morrey William P Cooney S Murali D R Hardten S DeMartelaere O M Olevsky E A Mindrup M L Hecht C C Chan E J Holland
Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.