DR. STERLING SCOTT REESE, M.D.

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This study examined how the indentation of stents in coronary arteries affects blood flow patterns and the risk of complications like stent re-narrowing (ISR) and blood clots. Researchers found that greater stent indentation leads to more frequent occurrences of harmful blood flow conditions, with high rates of critically low blood shear stress and other unfavorable indicators. These findings are important because they can help improve stent design and placement to reduce the risk of complications after heart procedures. Who this helps: This helps patients who receive stents, as well as doctors and researchers working on improving stent technology.

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This study focused on improving tissue-engineered implants by looking at how different conditions affect the growth of a key support structure called the extracellular matrix (ECM). Researchers found that growing these materials under stable conditions led to better ECM development, with non-reinforced scaffolds showing more collagen and better alignment with 63% higher collagen content. However, growing them under changing conditions actually suppressed ECM growth due to issues like washout. This matters because it helps create stronger and more effective implants for medical use. Who this helps: This benefits patients needing tissue repairs and doctors involved in implant procedures.

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This study looked at how effective two antiseptics, polyhexanide and hypochlorous acid, are for treating dog bite wounds to see if they could reduce the need for antibiotics. Researchers treated 34 dogs with bite wounds and found that 82.4% had positive bacterial cultures, with 41.2% showing drug-resistant bacteria. Both antiseptics worked similarly to clean the wounds, but choosing whether to use antibiotics depends on the severity of the wound. Who this helps: This helps veterinarians in deciding treatment plans for dogs with bite wounds.

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This study looked at how parents communicate with their adolescents and young adults (AYAs) who have blood cancer and identified topics that are uncomfortable for them to discuss. Researchers interviewed 20 parents and surveyed 80 more, finding that parents especially struggle with conversations about feelings, care information, sexual health, and mortality. Avoiding these discussions is linked to poorer communication skills and greater distress for parents. Who this helps: This research benefits parents caring for adolescents and young adults with blood cancer by providing tools to improve their communication.

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This study looked at the levels of a hormone called anti-Müllerian hormone (AMH) in dogs that have low sperm counts (oligozoospermia) or no sperm (azoospermia). Researchers found that the AMH levels in these dogs were significantly higher—almost certainly so—compared to healthy dogs, which could help identify dogs with fertility issues. This is important because it could aid veterinarians in diagnosing and treating fertility problems in dogs more effectively. Who this helps: This helps dog owners and veterinarians dealing with fertility issues in male dogs.

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This study looked at an enzyme called RslO9, which is involved in producing certain natural compounds that have potential medical benefits. Researchers discovered that instead of performing a previously thought oxidation reaction, RslO9 actually makes a different kind of chemical change, specifically producing a new intermediate called the Hooker intermediate. This finding changes how scientists understand this enzyme and similar ones, which can help in developing new drugs from these natural compounds. Who this helps: This benefits researchers and pharmaceutical developers working on new therapies.

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This study looked at how effective staying in your home can be during a radiological emergency, like a severe accident at a nuclear power plant. The researchers developed a method to analyze how well typical homes can protect people from radiation, finding that homes can significantly reduce radiation exposure for extended periods. For example, using the right ventilation can help keep indoor air cleaner, which is a new insight that goes against previous advice. Who this helps: This benefits patients living near nuclear plants and emergency responders.

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This study looked at how prostate cancer (PCa) showed up on MRIs in different racial groups, specifically focusing on lesions rated PI-RADS 3, which indicate uncertainty. Researchers found that among 646 patients, 45% of non-Hispanic Black men had detectable PCa, compared to 36% of Hispanic men and 35.8% of non-Hispanic White men. Notably, Black men had nearly five times higher odds of having significant prostate cancer from PI-RADS 3 lesions compared to the other groups. Who this helps: This research benefits clinicians and healthcare providers in understanding and managing prostate cancer risks in Black men.

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This study looked at the effects of high-impact chronic pain in people with sickle cell disease, focusing on how pain affects their daily activities and overall well-being. Researchers found that 56% of the participants experienced ongoing high-impact pain over six months, which was linked to more severe pain, greater fear of movement, and lower confidence in managing their pain. Understanding these dynamics is important because it highlights the need to address psychological factors in treating chronic pain among these patients. Who this helps: This helps patients with sickle cell disease and their doctors by identifying important factors that influence pain management.

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This study focused on creating recommendations to prevent hospital-onset urinary tract infections (HOUTIs), particularly highlighting non-catheter-associated UTIs, which haven’t had well-established prevention methods. The expert panel reached strong consensus on 37 key statements related to monitoring and preventing these infections, with at least 88% agreement on most topics. This is important because improving prevention strategies can significantly reduce the number of infections that patients acquire in hospitals, leading to better health outcomes and lower healthcare costs. Who this helps: This benefits patients in hospitals and healthcare providers who care for them.

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This study looked at a program called Bright IDEAS-Young Adults, which helps young adults with cancer develop problem-solving skills through telehealth sessions. A young adult patient participated in six sessions and reported feeling more confident in handling stress after completing the program, showing an improvement in their quality of life. This is important because it highlights how accessible support can make a difference for young cancer patients during a challenging time. Who this helps: Patients with cancer, especially young adults.

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This study looked at how the levels of a hormone called anti-Müllerian hormone (AMH) in female dogs relate to the number of puppies they have. The researchers found that AMH levels dropped during the heat cycle and that higher AMH levels were linked to larger litter sizes. Specifically, when body weight was taken into account, dogs with higher AMH levels had significantly larger litters, with a p-value of 0.022 for the first measurement and 0.030 for the second. Who this helps: This helps dog breeders by giving them a potential way to predict litter size based on hormone levels.

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This study looked at how well an "organ inventory" works for cancer screening instead of asking about a person's gender or sex assigned at birth. Researchers surveyed 333 people and found that the organ inventory was well-received, scoring an average of 18 out of 20 for acceptability. Using this approach identified some individuals who would have been missed if only gender or sex was considered, which is important for improving cancer screening for everyone. Who this helps: This benefits patients, especially those who are transgender, gender-diverse, or intersex.

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This study looked at how doulas can better support pregnant individuals dealing with substance use disorders in Montana. Researchers interviewed 29 people, including doulas and healthcare providers, and found three main areas for improvement: developing a trained doula workforce, removing financial and structural barriers to accessing doula care, and increasing acceptance of doulas focused on substance use issues in healthcare. This matters because enhancing doula support could lead to better outcomes for both mothers and infants during and after pregnancy. Who this helps: This helps pregnant individuals with substance use disorders, their families, and healthcare providers.

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This study explored a new way to use halogen bonding in a specific chemical reaction called the Diels-Alder reaction, which is important for making the drug fencamfamine. The researchers created a catalyst that successfully directed the reaction towards producing a single desired form of the drug with over 90% enantioselectivity, meaning it favored one version of the compound significantly over others. This is important because it could lead to more efficient and targeted methods for creating drugs in the future. Who this helps: This benefits pharmaceutical developers and researchers working on drug synthesis.

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This study looked at the whiskers, or vibrissae, of domestic dogs to understand their function. The researchers found that when the vibrissae are touched, dogs respond with reflex actions like blinking and moving their whiskers to investigate objects. The study confirmed that these whiskers have a complex structure with dense nerve connections, making them important sensory tools for dogs. Who this helps: This research is beneficial for dog owners and veterinarians who may consider the impact of grooming practices on a dog's sensory abilities.

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This study looked at how well a program called Mindful Self-Compassion (MSC) works for veterans dealing with feelings of guilt from moral injuries, as well as post-traumatic stress disorder (PTSD) and substance abuse problems. Twenty-six veterans participated in an 8-week MSC group, and the results showed that participants had meaningful improvements: self-compassion increased while PTSD symptoms, feelings of guilt and shame, and drinking days decreased. This is important because it highlights a potential new way to help veterans improve their mental health and reduce substance use. Who this helps: This benefits veterans struggling with PTSD and substance use issues.

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This study looked at the experiences of young adults with cancer who unexpectedly faced rapid health decline or death while participating in a support program called Bright IDEAS-YA. Researchers analyzed transcripts from 12 participants who completed 2 to 6 sessions of this program, revealing themes related to their cancer treatment, emotions, social systems, and thoughts about mortality. It highlighted the need for healthcare providers to actively engage with young patients to understand their values and goals, especially during critical times. Who this helps: This helps young cancer patients and their healthcare providers.

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This study focused on a type of cell called osteoclasts, which help break down bone tissue. Researchers found that mature osteoclasts, which have multiple nuclei, show different genetic activity compared to less mature osteoclasts, with those mature cells expressing more genes tied to their ability to function properly. This discovery is important because understanding the behavior of these cells can help improve treatments for cancer that spreads to bone. Who this helps: Patients with bone-related issues, especially those with cancer metastasis.

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This study focused on creating a new way to predict how engineered tissue, like heart valves and blood vessel replacements, grows and changes over time in the lab. The researchers developed a model that looks at how the tissue develops and reacts to pressure, showing promising results that could lead to more reliable and effective implants. Specifically, they tested this model with different shaped tissue samples and validated it against real experimental data, indicating it could improve the design of heart and blood vessel implants. Who this helps: This benefits patients needing heart or vascular surgeries.

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This study looked at the presence of different types of a virus called PCV2 in pig farms in Germany in 2024. Out of 87 farms, 31% had the virus, with 8% infected with one type (PCV2a), and 11.5% with another type (PCV2d). The findings show that PCV2d is more common, and vaccination did not influence the amount of virus found. Who this helps: This benefits pig farmers by providing important information on virus prevalence, assisting them in managing livestock health.

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This study looked at how iodotrifluoroethylene (ITFE) interacts with certain chemicals called phosphines. Researchers found that when these compounds form bonds, a specific measurement changed significantly: the C–C stretching mode shifted down by a large amount. Understanding these interactions is important because they can help in developing new materials or chemical reactions. Who this helps: This benefits researchers working on new materials and chemical processes.

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This study examined how using a special dye during CT scans can improve the diagnosis of elbow problems in dogs. Researchers looked at 326 elbow joints from 163 dogs that showed lameness and found that the dye helped identify issues that regular scans missed. Specifically, 137 joints showed enhanced details when the dye was used, allowing for better detection of conditions like joint capsule issues and muscle involvement, which can lead to improved treatment plans. Who this helps: This benefits veterinarians and dog owners by providing better diagnostic tools for treating elbow disorders in dogs.

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This study looked at how factors like age, lifestyle choices, and diseases affect the movement of tiny hair-like structures (cilia) in the fallopian tubes, which are important for transporting eggs and embryos. Researchers found that ciliary movement decreased significantly with age and was harmed by obesity, smoking, and certain gynecological issues, with women over 45 showing a strong decline in ciliary beat frequency (CBF) and a decrease in CBF in patients with conditions like ovarian cysts and cervical cancer. These findings are important because impaired ciliary function can lead to lower chances of successful pregnancies, suggesting that improving ciliary transport might help enhance the success rates of fertility treatments. Who this helps: This helps women facing fertility issues and healthcare providers involved in reproductive health.

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This study looked at how the canning process affects the levels of phosphorus in pet food, particularly focusing on the difference between harmful inorganic phosphorus and safer organic phosphorus. Researchers found that when pet food was canned, the amount of phosphorus that was soluble (and potentially harmful) decreased significantly. In fact, while raw samples showed a strong link between added inorganic phosphorus and total phosphorus content, the canned versions had much lower levels of soluble phosphorus, suggesting that commercial pet foods may contain more harmful phosphorus than previously thought. Who this helps: This information benefits pet owners and veterinarians by highlighting potential phosphorus-related health concerns in pet diets.

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This study focused on improving how doctors predict the recurrence of blockages in heart stents, a condition known as in-stent restenosis (ISR). Researchers developed a new model using a method called physics-informed neural networks (PINNs) that combines physical laws with patient data to better estimate ISR risk. Their approach could increase prediction accuracy, leading to better treatment planning and potentially improve outcomes for patients; for instance, it can refine stent placement based on individual patient factors. Who this helps: Patients with coronary stents.

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This study looked at how cystic ovary disease (COD) affects the reproductive tubes in dairy cows. Researchers found that different types of ovarian cysts changed the structure and function of the Fallopian tubes, impacting their ability to support sperm and potentially leading to fertility issues. This matters because understanding these effects can help develop new treatments for cows suffering from COD, improving their fertility and overall health. Who this helps: This research benefits dairy farmers and veterinarians working with affected cows.

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This study focused on improving the measurement of leg alignment in dogs using CT scans to help with orthopedic surgery. Researchers created a free software tool that accurately calculates angles in three-dimensional space, tested on 113 CT scans, and found that their new method was just as reliable as existing techniques. This matters because it enhances the precision of surgery for dogs with complex limb issues, which can lead to better surgical outcomes. Who this helps: This helps veterinary orthopedic surgeons and the dogs they treat.

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This study looked at the results of a specific eye surgery (phacoemulsification combined with vitrectomy) in horses suffering from cataracts caused by uveitis, a painful eye condition. The researchers treated 32 eyes from 28 horses and found that 85% of the eyes without a certain surgical step were visual one month after surgery, compared to 67% with that step. Over time, they noticed that the number of horses going blind from retinal detachment increased, even though the surgery helped reduce persistent uveitis. Who this helps: This benefits horses with cataracts due to uveitis and their veterinarians.

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The study looked at how well chronological age, health conditions, and frailty can predict whether patients who had surgery for degenerative scoliosis would be readmitted to the hospital within 90 days. Out of 8,104 patients, 9.8% were readmitted, mainly due to infections. While including age in the predictions did not make them significantly better, frailty alone was found to be a strong indicator of readmission risk. Who this helps: This helps doctors better assess which surgical patients are at higher risk of needing to return to the hospital.

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This study looked at how common osteoarthritis (OA) is in the shoulder, elbow, hip, and knee joints of dogs older than 8 years. Researchers found that about 39% of dogs had OA in their shoulders, 57% in their elbows, 36% in their hips, and 36% in their knees. This matters because it shows that OA is very prevalent among older dogs, highlighting the need for veterinarians to pay attention to joint health in aging pets. Who this helps: This information benefits dog owners and veterinarians by improving awareness and care for aging dogs.

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This study looked at a specific part of plant leaves called the petiole-lamina transition zone, which connects the leaf stem (petiole) to the leaf blade (lamina). Researchers used computer simulations to examine how well this area can handle different types of stress and found that the way fibers are arranged affects how much load this zone can bear. Understanding this zone is important because it helps in the transport of water and nutrients within the plant and can provide insights for creating better materials in construction. Who this helps: This benefits researchers studying plant biology and engineers designing new materials inspired by nature.

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This study looked at the levels of a hormone called anti-Müllerian hormone (AMH) in young male and female dogs and cats, specifically before and during puberty. Researchers collected 96 blood samples and found that male dogs and cats have higher AMH levels than females. In particular, female cats show a significant early rise in AMH levels compared to female dogs, where levels increase just before puberty. This is important because understanding these hormone levels can help in assessing the health and development of young pets. Who this helps: This research benefits veterinarians and pet owners by providing insights into the growth and reproductive health of dogs and cats.

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This study looked at how giving dogs with osteoarthritis (OA) a specific type of collagen supplement could help improve their movement and quality of life. Over 12 weeks, 31 dogs taking the collagen showed significant improvements in their mobility and less pain, measured through objective tests and owner questionnaires. This is important because it opens up a new treatment option for OA for both dogs and potentially humans, beyond just symptom relief. Who this helps: This benefits dogs with osteoarthritis, their owners, and may also help human patients with similar joint issues.

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This study created a calculator to help hospitals determine how many infection prevention specialists they need based on specific factors like hospital size and infection risk. The findings showed that the average number of specialists per 121 beds is not sufficient for about 79% of hospitals surveyed, leading to higher infection rates in certain conditions. This is important because having the right staff can significantly reduce infections, improving patient safety and care. Who this helps: This benefits patients and hospital administrators by ensuring adequate infection control staff.

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This study investigated the effects of a single injection of a treatment called stromal vascular fraction (SVF) in dogs suffering from elbow osteoarthritis that didn't improve with regular medications. Out of 23 dogs treated, 19 showed no worsening of their condition on X-rays, and over one-third had noticeable improvements in their limping. Additionally, about 26% of the dogs reported less pain during the study, with no side effects noticed. Who this helps: This information benefits dog owners and veterinarians seeking better treatment options for dogs with elbow osteoarthritis.

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Researchers studied respiratory diseases in pigs using a 24/7 artificial intelligence system that monitored coughing, alongside tests of oral fluids and air samples for pathogens. They found that higher levels of swine influenza virus in these samples were linked to poorer respiratory health in pigs, with oral fluids being more effective in detecting certain viruses compared to air samples. This matters because it can help farmers and veterinarians identify and manage respiratory diseases more effectively, leading to healthier pigs and better farm productivity. Who this helps: This benefits farmers and veterinarians working with pig populations.

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This study looked at a complex problem called coronary in-stent restenosis (ISR), which occurs when blood vessels narrow again after a stent is placed. The researchers developed a new method to analyze this process more efficiently, using advanced techniques to reduce the amount of data that needs to be processed. They found that the growth of tissue inside the stent happens most rapidly between 30 and 60 days after the procedure, and their model can predict how different drug dosages affect ISR rates, showing that certain dosages lead to more effective outcomes. Who this helps: This helps patients undergoing stent procedures and doctors guiding their treatment plans.

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This study examined how a virus that causes a deadly disease in cats, called feline infectious peritonitis (FIP), evades the immune system. Researchers found that in 31 cats with FIP, the infected cells were surrounded by proteins (called complement-regulating factors) that help protect these cells from being attacked by the immune system. Specifically, these protective factors were present in high amounts near the infected cells, while the immune system activation indicators were notably lower, showing how the virus manages to avoid destruction. Who this helps: This research benefits veterinarians and cat owners dealing with FIP.

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This study looked at whether cleaning the prepuce (the sheath covering the penis) of male dogs before mating is helpful in reducing harmful bacteria. Researchers tested 20 dogs and found that flushing with a specific solution called Caniprevent reduced bacterial growth by 20.8%. However, the overall benefits of this flushing before mating are still unclear, and more studies are needed for better guidance. Who this helps: Dog breeders and pet owners concerned about their dogs' health.

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The study looked at how injuries to blood vessels from stents might relate to a common problem known as in-stent restenosis (ISR), where arteries narrow again after being treated. Researchers found that strut indentation—where the stent presses into the blood vessel wall—was linked to greater injury and thicker arterial tissue growth. Specifically, they found a strong correlation between indentation and tissue growth, meaning more indentation led to more thickening (with scores like 0.5579 and 0.8620, both indicating a significant relationship). This research could help improve the way stents are implanted, potentially reducing the chance of complications for patients. Who this helps: This helps patients undergoing stent implantation and doctors performing the procedure.

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This study looked at infections related to stillbirth, mummification, embryonic death, and infertility in pigs, known as SMEDI syndrome, focusing on how multiple viruses might be present together. Researchers examined 158 fetuses from 40 affected litters across 18 farms and found that 69% of farms had the porcine parvovirus 1 (PPV1), while 55% had porcine circovirus 2 (PCV2) and 36% had porcine circovirus 3 (PCV3). The findings are significant because they show that fetuses infected with both PCV2 and PPV1 had worse outcomes, such as reduced size and weight, indicating that these combined infections can severely harm fetal development. Who this helps: This research benefits farmers and veterinarians managing pig health and reproductive issues.

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This study looked at the leg angles of six small dog breeds that are often affected by a knee condition called medial patellar luxation. Researchers used CT scans of 42 dogs and found significant differences in angles related to the thigh and shin bones between the breeds, showing that these angles vary by breed—Chihuahuas measured an average of 28.3 degrees for the anteversion angle, while Pugs measured 32.8 degrees. It’s important to understand these differences because they can help veterinarians make better decisions about surgeries for dogs with this condition. Who this helps: This research benefits dog owners and veterinarians dealing with knee issues in small dog breeds.

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This study looked at the challenges women face when trying to get mental health care during and after pregnancy, especially those dealing with substance use or existing mental health issues in rural Montana. Researchers interviewed seven women, revealing key problems like family history of mental health issues, stigma, a lack of awareness about postpartum depression, and feelings of isolation. Understanding these barriers helps create better mental health support for women in rural areas, enabling them to receive the care they need without fear of judgment. Who this helps: This benefits pregnant women and new mothers with mental health concerns and substance use issues.

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This study focused on creating a new type of support structure, called a scaffold, for artificial aortic valves made from heart tissue. The researchers found that their design, which used strong fibers and special materials, demonstrated good strength and function, meeting medical safety standards and performing better than natural heart valve tissue in several tests. This is important because it could lead to better artificial heart valves that work more effectively in patients' bodies. Who this helps: This benefits patients needing heart valve replacements.

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This study focused on developing a new type of imaging agent to help doctors distinguish between two conditions related to high aldosterone levels in the adrenal glands: bilateral hyperplasia and unilateral adenomas. Researchers created several compounds that could target the enzyme responsible for aldosterone production, finding some that were very effective, inhibiting the enzyme with very low amounts needed (less than 10 nanomoles) and showing strong selectivity (125 times stronger for one enzyme over the other). This matters because accurate diagnosis is crucial for effective treatment of patients with high blood pressure due to these conditions. Who this helps: Patients with primary aldosteronism and their doctors.

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This study focused on improving heart valves made from living tissue by modeling how they grow and strengthen. The research revealed that the new computer models can accurately predict how the tissue develops over time and how it responds under pressure, which is crucial for their function inside the body. These findings could lead to better heart valve implants that are more durable and effective for patients with heart conditions. Who this helps: Patients with cardiovascular diseases who may need heart valve replacements.

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This study focused on improving models that predict in-stent restenosis, which is when arteries become blocked again after being treated with drug-eluting stents. The researchers enhanced a computer model to better understand how certain drugs, like rapamycin, work in the body when embedded in these stents. They found that changing the amount of drug and how it's released can help improve treatment effectiveness, making the stents more beneficial for patients. Who this helps: This research helps patients who receive stents, as well as the doctors treating them.