Dr. Stranges studies the impact of diet and environmental factors on health, particularly in populations exposed to high levels of air pollution or those managing chronic conditions. His research has shown that consuming antioxidant-rich foods can improve respiratory and cardiovascular health for outdoor workers, like street vendors exposed to pollution. He also examines the relationship between insulin resistance, as measured by the triglyceride-glucose index, and mortality risk, highlighting how simple measurements can indicate serious health risks. Additionally, he investigates how lifestyle habits influence conditions such as multiple sclerosis, revealing that factors such as obesity, diet, and sleep quality can significantly affect disease progression.
Key findings
Street vendors eating antioxidant-rich foods reported 55% less coughing and 92% fewer irregular heartbeats over a year compared to those who did not change their diet.
A one-unit increase in the triglyceride-glucose index raised the overall mortality risk by 14% and heart-related death risk by 16%.
A 1 µg/m3 increase in PM2.5 air particles was linked to a 0.317 ms increase in heart tissue measurement, indicating early heart damage.
Frequently asked questions
Does Dr. Stranges study air pollution effects on health?
Yes, he researches how air pollution can impact respiratory and cardiovascular health, especially in vulnerable populations.
What treatments has Dr. Stranges researched?
He has looked into dietary changes, such as eating antioxidant-rich foods, and their potential benefits for health in polluted environments.
Is Dr. Stranges's work relevant to people with multiple sclerosis?
Yes, his research explores how lifestyle factors can influence the progression of multiple sclerosis and potential ways to improve patient outcomes.
Publications in plain English
Trajectories and predictors of sleep quality during and after the pandemic in five European populations.
2026
Sleep health
Lepinteur A, Vögele C, D'Ambrosio C, Stranges S
Plain English This study looked at how sleep quality changed during and after the COVID-19 pandemic in five European countries, analyzing data from over 8,000 people. Researchers found that overall sleep quality improved over time, but was affected by the pandemic's ups and downs, with factors like being female, having steady income, being active, and good mental health being linked to better sleep. These insights are important because they show that social and mental health factors greatly influence how well people sleep, and highlight the need to focus on sleep health in healthcare.
Who this helps: This helps patients and healthcare providers understand the importance of addressing sleep issues, especially in the wake of a major health crisis.
Association of planetary health diet indices with diet composition, nutritional quality and environmental impacts in Italian adults.
2026
Nutrition, metabolism, and cardiovascular diseases : NMCD
Tucci M, Martini D, Godos J, Olvera-Moreira MA, Fresán U +10 more
Plain English This study looked at how well Italian adults follow a diet called the Planetary Health Diet (PHD) and its effects on their nutrition and the environment. Researchers found that people who adhered more closely to PHD-related diets consumed more beneficial nutrients like fiber and aligned better with healthy eating guidelines, but some still had lower levels of essential nutrients like vitamin B12 and calcium. Overall, diets that followed the Mediterranean pattern were linked to better health outcomes and less environmental impact.
Who this helps: This research benefits patients looking for healthier eating patterns and sustainable diets, as well as doctors advising on nutrition.
SmartAPPetite For Youth: pilot and feasibility study of an adolescent smartphone nutrition intervention.
2026
Pilot and feasibility studies
Gilliland J, Bowman D, Cappuccitti S, Caruso O, Clark A +13 more
Plain English The study tested a smartphone app called "SmartAPPetite for Youth," designed to help adolescents improve their eating habits by sending them healthy eating tips and reminders for eight weeks. Out of 108 eligible teens, 59 agreed to use the app, and 54 completed the study; most found it helpful and would recommend it to friends. The initial findings indicate that the app can positively affect teenagers' food knowledge and choices, suggesting it could lead to healthier diets when tested more thoroughly.
Who this helps: This helps adolescents looking to improve their nutrition and health.
Examining diet quality among postsecondary students: a cross-sectional analysis of personal, social, structural, and environmental correlates.
2026
International journal of food sciences and nutrition
Schaafsma H, Seabrook J, McEachern LW, Haines J, Minaker L +4 more
Plain English This study looked at the eating habits of over 1,100 college students in Ontario, Canada, focusing on how personal beliefs, social factors, and living conditions affect their diet quality. The research found that students who had a positive view of healthy eating and more knowledge about nutrition tended to eat better, while those facing food insecurity or not following specific diets had poorer eating habits. Improving students' diets is important for their health and academic success, so efforts should aim to enhance their nutrition knowledge and address issues like food insecurity.
Who this helps: This helps college students who want to improve their eating habits.
The Role of Lifestyle Factors in Multiple Sclerosis: An Integrative Perspective.
2026
Brain sciences
Lanzillo R, Clerico M, Stranges S
Plain English This research looked at how daily habits like diet, sleep, exercise, and smoking influence multiple sclerosis (MS). Key findings revealed that being obese in adolescence increases the risk of MS, sleep problems can worsen brain health, and smoking speeds up disability progression. This matters because focusing on lifestyle changes alongside medical treatments could improve the health and well-being of people with MS.
Who this helps: Patients with multiple sclerosis.
Adherence to the Mediterranean Diet and Dietary Potassium Intake: A Narrative Review of Epidemiological Evidence.
2026
Nutrients
D'Elia L, Stranges S, Cappuccio FP, Strazzullo P, Galletti F
Plain English This research paper looked at how following the Mediterranean diet relates to potassium intake among adults. It found that people who closely follow this diet generally have higher potassium intake, though the results varied based on how adherence to the diet and potassium levels were measured. Understanding this connection is important because a higher potassium intake is linked to better health, especially in preventing diseases.
Who this helps: This benefits patients and health professionals looking to improve dietary recommendations for better health outcomes.
Association between Particulate Matter Air Pollution and Subclinical Myocardial Fibrosis in Structurally Normal Hearts: a CMR-based study.
2026
European heart journal. Cardiovascular Imaging
Figliozzi S, Filiberti G, Catapano F, Donia D, Lisi C +14 more
Plain English This study looked at how long-term exposure to fine air particles (PM2.5 and PM10) affects heart health in patients with normal hearts. Researchers found that higher levels of PM2.5 were connected to changes in heart tissue, which could indicate early signs of heart damage; specifically, a 1 µg/m3 increase in PM2.5 was linked to a 0.317 ms increase in a heart measurement that reflects tissue health. This is important because it suggests that air pollution may harm heart health even in people who don’t have visible heart problems.
Who this helps: Patients living in areas with high air pollution levels.
Triglyceride-Glucose Index and Mortality Risk in the General Population: A Systematic Review and Meta-analysis of Prospective Studies.
2026
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension
Lanfranco D, Stranges S, La Fata E, Fortunato F, Palladino R +2 more
Plain English This study looked at how the triglyceride-glucose (TyG) index, a simple and affordable way to measure insulin resistance, relates to the risk of death in the general population. Researchers found that for every one-unit increase in the TyG index, the risk of dying from any cause went up by 14%, and the risk of dying from heart-related issues rose by 16%. Knowing someone’s TyG index can help identify those at higher risk, making it a useful tool for early health assessments in the community.
Who this helps: This benefits patients, particularly those at risk for cardiovascular diseases and their doctors.
Consumption of antioxidant-rich foods attenuates respiratory and cardiovascular health effects in a population highly exposed to air pollution.
2026
Environmental epidemiology (Philadelphia, Pa.)
Amegah AK, Yeboah K, Quarshie E, Benjamin DO, Amonoo P +3 more
Plain English This study looked at how eating foods high in antioxidants can help street vendors in Accra, Ghana, who are regularly exposed to air pollution. Over a year, 155 street vendors who ate these foods had significantly fewer health issues, such as 55% less coughing, 60% less difficulty breathing, 92% fewer irregular heartbeats, and were 66% less likely to visit the hospital compared to those who did not change their diet. Despite some unexpected decline in lung function for those eating more antioxidants, the overall results show that these foods can improve health for people working in polluted environments.
Who this helps: This research benefits street vendors and other outdoor workers facing high air pollution.
Nutrition, metabolism, and cardiovascular diseases : NMCD
Chaput JP, Stranges S
Plain English This study focused on the importance of sleep for heart and metabolic health. It found that over 30% of people experience sleep issues like insomnia and sleep apnea, which can lead to serious health problems such as heart disease and diabetes. Improving sleep habits can significantly enhance overall health and reduce healthcare costs, making it crucial to include sleep health in medical care and public health strategies.
Who this helps: Patients and healthcare providers.
Identifying the factors affecting quality of life among brucellosis patients in Herat, Afghanistan: a case-control study.
2025
Infection ecology & epidemiology
Shayan NA, Rahimi A, Stranges S, Thind A
Plain English This study looked at how brucellosis, a serious infection, affects the quality of life of patients in Herat, Afghanistan. Researchers found that out of 155 participants, those with brucellosis had notably lower quality of life scores, especially males, with certain risk factors like being married, having lower education, and contact with pets linked to higher infection rates. Improving public health strategies is important to reduce these infections and enhance well-being in this area.
Who this helps: This helps patients suffering from brucellosis and healthcare providers working to treat them.
Differential expression of plasma proteins and pathway enrichments in pediatric diabetic ketoacidosis.
2025
Molecular medicine (Cambridge, Mass.)
Spagnolo P, Cela E, Patel MA, Tweddell D, Daley M +4 more
Plain English This study looked at the changes in proteins in the blood of children with type 1 diabetes who are experiencing a serious condition called diabetic ketoacidosis (DKA). Researchers found 214 proteins that were present in different amounts in kids with severe DKA compared to those safely managing their diabetes. Notably, 162 proteins were more abundant, indicating significant inflammation and stress related to the DKA condition, which could help explain the serious complications associated with it.
Who this helps: This research benefits pediatricians and healthcare providers who treat children with diabetes, as it offers insights into managing severe DKA more effectively.
Association between recorded physical activity and cancer progression or mortality in individuals diagnosed with cancer in South Africa.
2025
British journal of sports medicine
Mabena N, Rugbeer N, Lehmann S, Torres G, Patel D +6 more
Plain English This study looked at how physical activity levels before a cancer diagnosis affected the progression of the disease and overall mortality in people with stage 1 cancer in South Africa. Among 28,248 participants, those who were physically active experienced less cancer progression and lower death rates; specifically, moderate to high activity reduced the risk of progressing or dying by 27% compared to no activity. This matters because it shows that being active can significantly improve outcomes for cancer patients.
Who this helps: This helps cancer patients by highlighting the importance of physical activity in improving their health outcomes.
Prevalence of post-acute sequelae of SARS-CoV-2 infection in people living with HIV: a systematic review with meta-analysis.
2025
EClinicalMedicine
Pouliopoulou DV, Billias N, MacDermid JC, Miller E, O'Brien KK +7 more
Plain English This study looked at how common Long COVID is among adults living with HIV and if they are more likely to develop Long COVID compared to those without HIV. They found that about 43% of adults with HIV experience Long COVID symptoms, and those with HIV might be over twice as likely to develop Long COVID compared to others, although the evidence is not very strong. Understanding this is important because it points to the need for doctors and health policymakers to be more aware of the risks facing patients with HIV after COVID-19.
Who this helps: This helps patients with HIV and their healthcare providers.
The co-occurrence of multimorbidity and polypharmacy among middle-aged and older adults in Canada: A cross-sectional study using the Canadian Longitudinal Study on Aging (CLSA) and the Canadian Primary Care Sentinel Surveillance Network (CPCSSN).
2025
PloS one
Nicholson K, Salerno J, Borhan S, Cossette B, Guenter D +10 more
Plain English This study looked at the overlap of having multiple health conditions (multimorbidity) and taking many medications (polypharmacy) among middle-aged and older Canadians. It found that 66.7% of older adults in one group and 52% in another had multiple conditions, while 14.9% and 22.6% were on five or more medications, respectively. About 20% of older adults were dealing with both issues at once, highlighting a significant health concern as this is much higher than the nearly 10% in middle-aged adults.
Who this helps: This benefits older patients and healthcare providers working to manage their care.
Investigation of rural-urban differences in hospitalization for ambulatory care-sensitive conditions: Analysis of linked survey, hospitalization, and tax data from Canada.
2025
The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association
Bai Y, Stranges S, Sarma S
Plain English This study looked at how often people in rural and urban areas of Canada are hospitalized for health issues that could have been managed with proper primary care, called ambulatory care-sensitive conditions (ACSCs). Between 2007 and 2019, researchers found that while the gap between rural and urban hospitalization rates for these conditions has narrowed, rural areas still saw higher hospitalization rates, especially among lower-income and less-educated populations. This is important because it highlights the need for better access to primary care in rural regions to prevent unnecessary hospital visits.
Who this helps: This benefits patients living in rural areas, especially those with lower income and education levels.
Diet, fruit and vegetables and One Health: benefits for health, environment, society and the consumer-proceedings of the 9th edition of EGEA conference.
2025
European journal of nutrition
Komati N, Riboli E, Dore J, Boyland E, Cravedi JP +35 more
Plain English This study focused on the benefits of diets high in fruits and vegetables for human health and the environment. Researchers found that eating more fruits and vegetables can help prevent heart disease and type 2 diabetes, and they emphasized the need for more research on how these foods might protect against cancer. Additionally, growing and eating more fruits and vegetables supports community health and is better for the planet, despite challenges like pesticide use.
Who this helps: This helps patients and communities by promoting healthier eating habits and sustainable agricultural practices.
Disability and unmet need for health care in Canada: Findings from the Canadian Community Health Survey.
2025
Disability and health journal
Pucchio AMR, Stranges S, Ali S
Plain English This study looked at how many people in Canada with disabilities are not getting the health care they need compared to those without disabilities. Researchers found that individuals with disabilities were over four times more likely to report unmet health care needs, mainly due to problems like long wait times and lack of services. This is important because it shows a significant gap in health care access for people with disabilities, highlighting the need for policies to improve care availability for this group.
Who this helps: Patients with disabilities and health care providers.
Dietary Patterns and Brain Health in Middle-Aged and Older Adults: A Narrative Review.
2025
Nutrients
Seabrook JA, Avan A, O'Connor C, Prapavessis H, Nagamatsu L +4 more
Plain English This study looked at how different diets affect brain health in middle-aged and older adults, who are more likely to experience memory loss and other cognitive issues. It found that the Mediterranean diet consistently helps improve memory and thinking skills, while the DASH and MIND diets show some benefits, but less consistently. On the other hand, a Western diet is linked to worse brain health, including memory decline and smaller brain size.
Who this helps: This helps patients and anyone looking to improve their brain health as they age.
Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attacks or Mild Non-Disabling Strokes: A Feasibility and Effectiveness Randomized Controlled Trial.
2025
Journal of cardiopulmonary rehabilitation and prevention
Majoni M, Stranges S, Chan RKT, Suskin N, Prior PL
Quick fixes, lasting problems: Rethinking obesity management through a public health lens beyond pharmacological solutions.
2025
Nutrition, metabolism, and cardiovascular diseases : NMCD
Cuschieri S, Cuschieri A, Ali S, Stranges S
Plain English This study looks at the growing trend of using medications to treat obesity and points out the problems with this approach. It found that while these drugs can lead to significant weight loss in the short term, they ignore deeper issues like unhealthy food environments and economic factors that contribute to obesity. By focusing too much on medications, we risk missing the bigger picture and making it harder for vulnerable groups to access treatment.
Who this helps: This helps patients struggling with obesity and healthcare providers seeking effective long-term solutions.
The socioeconomic patterning of physical activity among middle-aged and older adults in Canada using the Canadian Longitudinal Study on Aging (CLSA) data.
2025
Canadian journal of public health = Revue canadienne de sante publique
Yuan J, Ali S, Nicholson K, Stranges S, Thornton J
Plain English This study looked at how people's wealth and education affect their chances of meeting physical activity guidelines in Canada, specifically among middle-aged and older adults. It found that only 21.2% of participants met the recommended 150 minutes of moderate-to-vigorous physical activity each week. Those with more than $1 million in wealth were 50% more likely to be active compared to those with less than $50,000, highlighting significant socioeconomic inequalities in physical activity levels.
Who this helps: This research benefits public health officials and policymakers aiming to improve physical activity among older adults.
How Accurate Is Multiple Imputation for Nutrient Intake Estimation? Insights from ASA24 Data.
2025
Nutrients
Woods N, Gilliland J, McEachern LW, O'Connor C, Stranges S +2 more
Plain English This study looked at how well a method called multiple imputation (MI) can estimate nutrient intake in adolescents when some dietary data is missing. Researchers analyzed data from 743 teenagers in Ontario and found that MI was not very accurate: the estimates of nutrient intake matched the actual values only about 25% of the time and the correlation between them was weak (around 0.24). This matters because accurate dietary assessment is essential for understanding nutrition in public health, but if the methods are unreliable, it could lead to incorrect conclusions.
Who this helps: This helps researchers and public health officials working with adolescent dietary data.
Sleep patterns of Canadian women across the life course: A systematic review.
2025
Women's health (London, England)
Woods SE, Nistor P, Anderson KK, Stranges S
Plain English This study looked at the sleep patterns of Canadian women throughout their lives, comparing them to men's sleep when possible. It found that among nearly 26 million participants, women faced more sleep issues, especially during key life stages like pregnancy and menopause, with a notable number of adult women experiencing sleep problems compared to men. Understanding these differences is crucial for improving women's sleep health and overall well-being.
Who this helps: This helps women, especially those going through specific life transitions like pregnancy and menopause.
Social and health determinants of wait times for primary care in Canada.
2025
Canadian family physician Medecin de famille canadien
Le B, Stranges S, Ali S
Plain English This study looked at the factors that influence how long people in Canada wait to see a primary care doctor. It found that about 57% of people waited less than a week for an appointment, but 11% faced waits of a month or longer. Key factors that led to longer waits included having only a high school diploma, identifying as Asian or Black, not having a regular healthcare provider, reporting excellent health, and having multiple chronic health issues. Understanding these issues is important because it can help make healthcare more equitable and accessible for everyone.
Who this helps: This helps patients by highlighting the barriers they face in getting timely care.
Mediating pathways between area-level deprivation and hypertension in Nepal: the role of nutritional status, food insecurity, and health behaviors.
2025
BMC public health
Sharma I, Campbell MK, Choi YH, Luginaah I, Were JM +2 more
Plain English This study looked at how living in poorer areas in Nepal relates to high blood pressure (hypertension) and found that about 22.9% of people have hypertension. Interestingly, the risk of high blood pressure was higher in wealthier areas (27.5%) compared to poorer ones (17.9%), and poor nutrition, measured by Body Mass Index (BMI), played a significant role in this relationship, accounting for around 70% of the impact. This matters because it highlights the importance of nutrition in managing health risks, especially as living conditions change in Nepal.
Who this helps: This helps patients and public health officials working to improve health strategies in low-income areas.
Protection from second booster vaccines and natural immunity against SARS-CoV-2 infections, 2022-2023.
2025
Epidemiology and infection
Bejko D, Vergison A, Stranges S, Mossong J, Zeegers M
Plain English This study looked at how effective second booster vaccines and natural immunity are at preventing COVID-19 infections in people aged 60 and older in Luxembourg. Researchers found that the effectiveness of the monovalent and bivalent vaccines dropped significantly over time, from about 65% in the first month to only 1.5% and 16.5%, respectively, after 5 to 6 months. In contrast, natural immunity from previous infections provided longer-lasting protection, with about 81% still protected at 4 to 8 months and 45% at 15 to 25 months after getting infected.
Who this helps: This information is beneficial for older adults and their healthcare providers when making vaccination decisions.
Short- and Long-Term Predicted and Witnessed Consequences of Digital Surveillance During the COVID-19 Pandemic: Scoping Review.
2024
JMIR public health and surveillance
Comer L, Donelle L, Hiebert B, Smith MJ, Kothari A +10 more
Plain English This study looked at how various digital technologies, like mobile apps and drones, were used for monitoring public health during the COVID-19 pandemic across 90 countries. Researchers reviewed 226 publications and found that while these tools helped manage health efforts, they also raised serious concerns about privacy and the rights of marginalized groups. Recognizing these issues is crucial for ensuring that digital surveillance is used responsibly in future health crises.
Who this helps: This benefits patients and communities by advocating for responsible digital health practices.
Birth weight mediates the association of maternal undernutrition with child undernutrition prevalence in West Africa.
2024
European journal of clinical nutrition
Kofi Amegah A, Ayinemi R, Sewor C, Fenta HM, Yeboah K +5 more
Plain English This study looked at how mothers' poor nutrition affects their children's growth and health in West Africa. It found that 32.4% of young children in the region are stunted (too short for their age), and children born to underweight or anaemic mothers are more likely to be undernourished. Low birth weight is a key factor, linking maternal nutrition to childhood undernutrition, with significant effects on stunting (about 23% related to maternal weight) and anaemia (about 7% related to maternal anaemia).
Who this helps: This benefits mothers and children in West Africa by highlighting the need for better maternal nutrition to improve child health.
High vaccine effectiveness against severe COVID-19 outcomes and population preventable fraction during the Omicron era in Luxembourg: A nationwide retrospective risk factor analysis.
2024
Vaccine
Bejko D, Ernst C, Vergison A, Stranges S, Zeegers MP +1 more
Plain English This study examined the effectiveness of COVID-19 vaccines against severe outcomes like hospitalization and death in Luxembourg during the Omicron variant wave. Researchers found that fully vaccinated individuals had a 38.8% lower chance of being hospitalized compared to those unvaccinated, while those with one and two booster doses saw even greater effectiveness at 62.1% and 71.6%, respectively. Overall, vaccinations significantly decreased hospital admissions by 49.1% and deaths by 55.8%, demonstrating that vaccines greatly protect against severe COVID-19 effects.
Who this helps: This benefits patients, especially those at higher risk like the elderly and residents of nursing homes.
Risk factors for prevalent and incident hypertension in rheumatoid arthritis: data from the Canadian Early Arthritis Cohort.
2024
Rheumatology advances in practice
Hadwen B, Stranges S, Pope JE, Bartlett S, Boire G +11 more
Plain English This study looked at high blood pressure (hypertension) in patients with early rheumatoid arthritis (RA) using data from over 2,000 individuals. They found that 26% of patients had hypertension when they started the study, and over a 5-year follow-up, 24% of those without hypertension developed it, especially older individuals or those who were overweight or consumed a lot of alcohol. Understanding these risk factors is important because it highlights the need for monitoring and managing blood pressure in RA patients to prevent further health issues.
Who this helps: This helps patients with rheumatoid arthritis and their doctors.
Rural-Urban Divide in the Prevalence and Correlates of Overweight and Obesity Among Women of Reproductive Age in Nigeria: A Multilevel Analysis of Repeated Cross-Sectional Data.
2024
Ecology of food and nutrition
Were JM, Kyeremeh E, Annor BOH, Campbell MK, Stranges S
Plain English This study looked at the rates of overweight and obesity among women of reproductive age in both rural and urban areas of Nigeria. Between 2008 and 2018, the number of women classified as overweight rose from 16.1% to 18.2%, and those categorized as obese increased from 6.1% to 10.0%. Factors like age, marital status, and education were connected to higher risks for being overweight or obese, and unique challenges varied between rural and urban settings, impacting how these women's health is managed.
Who this helps: This helps healthcare providers and policymakers focus on specific risks for women in different regions.
The x-ray absorption spectrum of the tert-butyl radical: An experimental and computational investigation.
2024
The Journal of chemical physics
Schaffner D, Juncker von Buchwald T, Karaev E, Alagia M, Richter R +3 more
Plain English This study looked at the x-ray absorption spectrum of a chemical compound called the tert-butyl radical. Researchers used high-temperature methods to create this radical and then analyzed its properties, finding that the core electrons in different carbon atoms behave differently when excited. Notably, they discovered that certain excitations lead to the radical breaking apart into smaller pieces, which could inform how we understand chemical reactions involving similar compounds.
Who this helps: This helps chemists and researchers working with organic radicals.
Structure and fragmentation of doubly ionized HNCS.
2024
The Journal of chemical physics
Wallner M, Olsson E, Ideböhn V, Parriani M, Squibb RJ +10 more
Plain English This study explored the behavior of isothiocyanic acid (HNCS) when it loses two electrons, a process known as double ionization. Researchers found that the energy required for this double ionization is about 27.1 electron volts and also determined a specific energy of 30.95 electron volts for one of the fragments produced during this process. These findings help us understand how molecules change when they lose electrons, which is important for fields like chemistry and materials science.
Who this helps: This benefits scientists and researchers working in chemistry and material science.
Using causal diagrams within the Grading of Recommendations, Assessment, Development and Evaluation framework to evaluate confounding adjustment in observational studies.
2024
Journal of clinical epidemiology
McIntyre KJ, Tassiopoulos KN, Jeffrey C, Stranges S, Martin J
Plain English This study looked at ways to improve the evaluation of observational studies, which can sometimes be misleading due to confounding factors. The researchers proposed using causal diagrams within the GRADE system to provide a clearer and more consistent way to assess whether these studies have properly accounted for such confounding. This new method could lead to better, more trustworthy recommendations in healthcare because it strengthens how we understand the evidence from studies.
Who this helps: Patients and doctors who rely on accurate study outcomes for treatment decisions.
Incorporating Social Determinants of Health in Infectious Disease Models: A Systematic Review of Guidelines.
2024
Medical decision making : an international journal of the Society for Medical Decision Making
Ali S, Li Z, Moqueet N, Moghadas SM, Galvani AP +9 more
Plain English This study looked at how infectious disease models, which help guide policy decisions (like during COVID-19), often ignore important social factors that affect health, such as age, gender, and socioeconomic status. Researchers reviewed 19 guidelines and found that 14 of them recognized the importance of these social factors, suggesting that including them can improve the accuracy of predictions and better address health inequalities. This is crucial because it can lead to more effective strategies for controlling diseases and ensuring that everyone has equal access to health resources.
Who this helps: This helps patients and public health policymakers.
Cross-sectional and prospective associations between sleep health and multimorbidity in middle to older-aged adults: Results from the Canadian Longitudinal Study on Aging (CLSA).
2024
Sleep medicine
Patel S, Speechley M, Nicholson K, Espin-Garcia O, Reid GJ +1 more
Plain English This study looked at how sleep health is linked to having multiple chronic health issues in adults aged 45 to 85 in Canada. Researchers found that for every 1-unit increase in a sleep health score (indicating worse sleep), the risk of having multiple chronic conditions increased by 48% at the start of the study and by 33% over time. This is important because it shows that improving sleep health might help reduce the number of chronic diseases in older adults.
Who this helps: Patients dealing with sleep problems and chronic health conditions.
Do COVID-19 Infectious Disease Models Incorporate the Social Determinants of Health? A Systematic Review.
2024
Public health reviews
John-Baptiste AA, Moulin M, Li Z, Hamilton D, Crichlow G +16 more
Plain English This study looked at how COVID-19 models considered social factors, like age, gender, and location, that can affect health. Out of 83 models reviewed, age was the most frequently included factor in 74 studies, while only a handful considered race or rural living. Understanding these social determinants is crucial because without them, we miss important insights on how different groups are affected by the pandemic and what targeted help they might need.
Who this helps: This helps public health officials and policymakers improve responses to COVID-19 for diverse communities.
Age and sex differences in the association of dental visits with inadequate oral health and multimorbidity: Findings from the Canadian Longitudinal Study on Aging (CLSA).
2024
BMC public health
Limo L, Nicholson K, Stranges S, Gomaa NA
Plain English This study looked at how often people visit the dentist and how it’s related to their oral health and overall health, especially in older adults. The researchers found that those who visited the dentist regularly had better oral health and lower chances of having multiple chronic diseases; for instance, people who visited the dentist were 59% less likely to report poor oral health (0.41 odds), and 14% less likely to have multiple chronic conditions (0.86 prevalence ratio). These results show that regular dental visits can significantly improve health, especially for older adults and women.
Who this helps: This helps patients, particularly older adults, improve their oral and overall health.
Perioperative mortality in low-, middle-, and high-income countries: Protocol for a multi-level meta-regression analysis.
2024
PloS one
McIntyre KJ, Choi YH, John-Baptiste A, Lizotte DJ, Chan EYS +3 more
Plain English This study looks at how many adults die around the time of surgery in different countries, focusing on a specific type of surgery commonly used to gauge surgical safety. Researchers plan to review existing studies to find out the rates and causes of these deaths over time. Their findings will provide important data that can help improve surgical safety measures globally.
Who this helps: This information benefits patients and healthcare policymakers.
Prevalence, Characteristics, and Outcomes of People With A High Body Mass Index Across the Kidney Disease Spectrum: A Population-Based Cohort Study.
2024
Canadian journal of kidney health and disease
Sahi G, Reid J, Moist L, Chiu M, Vinson A +4 more
Plain English This study looked at how common obesity is among people with chronic kidney disease (CKD) in Canada. It found that 37% of patients with early-stage CKD and 40.9% of those with more advanced CKD had obesity (a BMI of 30 or higher), and these patients also faced more health issues and used more healthcare resources. Interestingly, while those with higher BMI had a lower likelihood of receiving a kidney transplant, they experienced fewer complications if they did get one.
Who this helps: This benefits patients with chronic kidney disease, particularly those who are also obese.
Suboptimal Oral Health, Multimorbidity, and Access to Dental Care.
2024
JDR clinical and translational research
Limo L, Nicholson K, Stranges S, Gomaa N
Plain English This study looked at how poor oral health is linked to having multiple health issues in adults aged 45 to 84 in Canada. The researchers found that people with bad oral health, like missing teeth or reported dental problems, were 44% more likely to have multiple chronic conditions, such as diabetes or heart disease. Access to dental care played a significant role; those who had fewer dental visits or could not afford dental care had an even higher risk of poor health.
Who this helps: This research helps patients with oral health problems and chronic conditions, as well as doctors and policymakers aiming to improve dental care access.
Metabolomic signature of pediatric diabetic ketoacidosis: key metabolites, pathways, and panels linked to clinical variables.
2024
Molecular medicine (Cambridge, Mass.)
Spagnolo P, Tweddell D, Cela E, Daley M, Clarson C +5 more
Plain English This study focused on understanding the metabolic changes that occur during diabetic ketoacidosis (DKA) in children with type 1 diabetes. Researchers analyzed blood samples from 34 participants and found 65 metabolites that significantly differed between those with severe DKA and those with controlled insulin levels, achieving an impressive 100% accuracy in identifying severe cases. These findings highlight the important metabolic disruptions in severe DKA and their link to clinical measures, which could help in early detection and treatment decisions.
Who this helps: This research helps doctors and healthcare providers manage and treat children with type 1 diabetes experiencing DKA.
Plain English This study looked at a program called Hockey Fans in Training (Hockey FIT) that aimed to help men with overweight or obesity improve their health by connecting them with their love for hockey. Men who participated in the program lost an average of 2.02 kg after a year, while those in a control group lost only 0.92 kg—showing a significant difference of 1.10 kg. This matters because it offers a fun and engaging way for men to make positive lifestyle changes, potentially reducing their risk of health problems.
Who this helps: This helps men with overweight or obesity who are fans of hockey, as well as healthcare providers looking for effective intervention strategies.
Shehzad Ali Kathryn Nicholson Colleen O'Connor Jason Gilliland Yun-Hee Choi Sarah Cuschieri Kelvin Yeboah Ngianga-Bakwin Kandala Ferruccio Galletti Louise W McEachern
Physician data sourced from the
NPPES NPI Registry
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Publication data from
PubMed
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Plain-English summaries generated by AI.
Not medical advice.