Bicarbonate reabsorption in chronic renal failure studies in man and the rat.
1978Pflugers Archiv : European journal of physiology
Arruda JA, Nascimento L, Arevalo G, Baranowski RL, Cubria A +3 more
PubMedDR. THOMAS (TOMAS) CARRASQUILLO JR., M.D.
CAPE CORAL, FL
Surgery NPI registered 21+ years 2 publications 1976 – 1978 NPI: 1801899786
What does THOMAS (TOMAS) CARRASQUILLO research?
Dr. Carrasquillo studies how kidneys operate when they are healthy versus when they are not functioning properly, specifically in cases of chronic renal failure, a condition where the kidneys gradually lose their ability to filter waste from the blood. His work dives into how kidney damage affects the absorption of bicarbonate, a substance that helps maintain the body's pH balance. He investigates the underlying mechanisms that lead to changes in kidney function when they are injured, which is critical for developing better treatment options for individuals with chronic kidney disease.
Key findings
- In dogs with kidney failure, there was a recorded 21% reduction in blood filtration compared to healthy kidneys.
- Blood flow to the kidneys was reduced by 37% in the failed kidneys, highlighting serious impairments in function.
- Even in injured kidneys, bicarbonate absorption was still higher than expected, suggesting unknown factors influencing this process.
Frequently asked questions
- Does Dr. Carrasquillo study chronic kidney disease?
- Yes, he specifically researches kidney function in the context of chronic renal failure.
- What findings are important from his research?
- His studies found significant reductions in blood filtration and flow in kidneys that are not functioning properly, which can influence treatment strategies.
- How does his work help kidney disease patients?
- His research provides insights that could lead to improved treatments and management of chronic kidney disease.
- What is bicarbonate absorption and why is it important?
- Bicarbonate absorption is the process by which kidneys manage the levels of bicarbonate in the blood, which is crucial for maintaining acid-base balance in the body.
Publications in plain English
Bicarbonate reabsorption in chronic renal failure.
1976Kidney international
Arrud JA, Carrasquillo T, Cubria A, Rademacher DR, Kurtzman NA
Plain English
This study looked at how kidneys in dogs handle bicarbonate when they are not functioning properly due to kidney failure. It found that even when the kidneys are injured, they absorb more bicarbonate compared to healthy kidneys—specifically, around 21% less blood filtration and 37% less blood flow was recorded in the failed kidneys. This is important because it suggests that there are factors affecting bicarbonate absorption in kidney failure that are not yet understood, which can impact treatment strategies.
Who this helps: This benefits doctors and patients with chronic kidney disease.
Frequent Co-Authors
A Cubria N A Kurtzman J A Arruda L Nascimento G Arevalo R L Baranowski C Westenfelder J A Arrud D R Rademacher
Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.