Dr. Cross studies several areas in medicine, including how certain types of cancer and infections behave, the effectiveness of surgical techniques, and the impact of lifestyle practices like yoga on women's health. For instance, he has researched the nuances of diagnosing bone tumors that may resemble metastasis from other cancers, the potential misdiagnosis of endometriosis using transvaginal ultrasound, and how antibiotic resistance is becoming a critical concern in treating specific bacterial infections. Additionally, he is interested in understanding how resistance exercise can affect eye health and ways to improve diagnosis for conditions like dry eye syndrome and Sjögren's syndrome.
Key findings
In a study of women practicing therapeutic yoga, 12 studies showed that yoga helps reduce pain and stress, improving overall mental and physical health outcomes.
During robotic colorectal surgeries with a dedicated assistant, operation times were significantly reduced, particularly for rectal surgeries, leading to more efficient surgical workflows.
A significant 90% of patients with ACL injuries showed healing on MRI using the Cross Bracing Protocol without surgery; those with better healing reported better knee function, with 92% returning to sports.
Frequently asked questions
Does Dr. Cross study cancer?
Yes, he researches various types of cancer, including rare tumors and the impact of imaging in cancer diagnosis.
What treatments has Dr. Cross researched?
He has investigated non-surgical management techniques for ACL injuries and the use of therapeutic yoga to improve health outcomes for women.
Is Dr. Cross's work relevant to patients with infections?
Absolutely, he studies antibiotic resistance in bacterial infections, emphasizing the need for cautious antibiotic use.
What can I learn about eye health from Dr. Cross's research?
He has explored how resistance exercise affects intraocular pressure, which is important for those concerned about eye health and conditions like glaucoma.
How does Dr. Cross's work help patients with dry eyes?
His research into the RNA profiles of tear fluid could lead to easier and more accurate diagnosis of dry eye-related symptoms.
Publications in plain English
A new way of grading severity of ACL rupture on acute MRI to consider potential for non-surgical healing with the Cross Bracing Protocol: ACL Acute Rupture Characteristics for Healing (ACL-ARCH) MRI criteria.
2026
Journal of science and medicine in sport
Filbay SR, Dowsett M, van Haeringen M, Palmer E, Roger G +4 more
Dedicated bedside assistance improves operative efficiency in robotic colorectal surgery: A retrospective comparative study.
2026
American journal of surgery
Oruc M, Cross T, Karahan S, Spivak A, Erkaya M +3 more
Plain English This study looked at how having a dedicated assistant at the bedside during robotic colorectal surgeries affects the surgery's efficiency and outcomes. Researchers analyzed 148 surgery cases and found that having this assistant reduced the time spent on procedures, especially for rectal surgeries, where operation times were shorter and workflows improved. This matters because it shows that dedicated bedside assistance can make surgeries faster and potentially safer, especially in complex cases.
Who this helps: This helps patients undergoing robotic colorectal surgery and the surgeons who perform these procedures.
Prevalence and mechanisms of high-level carbapenem antibiotic tolerance in clinical isolates of Klebsiella pneumoniae.
2026
PLoS pathogens
Cross T, Torres F, Nikulin N, McGee AP, Jalees L +5 more
Plain English Researchers studied how common it is for Klebsiella pneumoniae, a type of bacteria, to survive high doses of the last-resort antibiotic meropenem. They discovered that many strains of this bacteria can tolerate the antibiotic, with findings showing that various genetic mechanisms help them survive and recover after the drug is removed. This is significant because it means we need to be more careful with our antibiotic use to avoid making these infections harder to treat.
Who this helps: This helps patients by highlighting the need for better antibiotic treatment strategies.
Giant Cell Tumor of Bone With Intense PSMA PET/CT Avidity Simulating Bone Metastasis From Prostate Cancer.
2026
Clinical nuclear medicine
Reichart J, Cross T, Torrado C, Couturier OF
Plain English This study examined a 74-year-old man who had a return of prostate cancer after surgery. Imaging tests showed a significant uptake of a marker associated with prostate cancer in a bone lesion, leading doctors to suspect it was cancer spreading to the bone. However, a closer look revealed that it was actually a giant cell tumor of the bone, not prostate cancer metastasis, highlighting that these imaging tests can sometimes mislead doctors into thinking there’s a spread of cancer when it’s something else.
Who this helps: This helps doctors accurately diagnose bone issues in patients with prostate cancer.
Systematic Review of the Lived Experiences of Women Participating in Therapeutic Yoga.
2026
International journal of yoga therapy
Cross T, Elliott C, Depa N, Furness J, Kemp-Smith K
Plain English This study looked at the experiences of women who participated in therapeutic yoga, focusing on its effects on their mental and physical health. Researchers reviewed 12 studies and found that yoga helped women build community, relieve pain, manage stress, and gain confidence. It highlighted that many women joined yoga classes to heal and feel connected to others, showing its potential benefits for women's health during various life stages.
Who this helps: This helps women dealing with health issues and transitions, like cancer, menopause, and pregnancy.
MRI deep learning models for assisted diagnosis of knee pathologies: a systematic review.
2025
European radiology
Mead K, Cross T, Roger G, Sabharwal R, Singh S +1 more
Plain English Researchers reviewed existing studies on deep learning models that analyze MRI scans to help diagnose knee problems. They found that these models, particularly those tailored to specific injuries, were up to 4.5% more accurate than models looking for general knee irregularities. This is important because improving diagnostic accuracy can lead to better treatment for knee conditions, benefiting patient outcomes and healthcare costs.
Who this helps: Patients with knee injuries and osteoarthritis.
Plain English This study looked at how some bacteria are able to survive high doses of the antibiotic meropenem, which is often used as a last resort against infections. The researchers found that many clinical samples of bacteria called Enterobacterales showed this tolerance, and they identified several genetic factors that help these bacteria survive even after the antibiotic is removed. This matters because understanding how bacteria resist treatment can guide better strategies to combat infections and develop new therapies.
Who this helps: This helps patients with serious bacterial infections and doctors treating them.
Transvaginal Ultrasound for the Diagnosis of Endometriosis: Current Practices and Barriers in Australian Sonographers.
2025
Australasian journal of ultrasound in medicine
Yang X, Deslandes A, Cross T, Childs J
Plain English This study looked at how Australian sonographers use transvaginal ultrasound (TVUS) to diagnose endometriosis and the challenges they face. Out of 127 surveyed sonographers, only 48% regularly performed a full or partial TVUS for endometriosis, with many focusing on basic assessments rather than searching for lesions. The main barriers to routine use included a lack of supervision and training, while a strong motivation to accurately identify endometriosis and available education opportunities helped encourage its use.
Who this helps: This benefits patients needing accurate diagnosis and treatment for endometriosis.
The Genomic Signature of Demographic Decline in a Long-Distance Migrant in a Range-Extreme Population.
2025
Molecular ecology
Day G, Bolderstone T, Conway GJ, Cross T, Davis T +18 more
Plain English This study examined the genetic health of the European nightjar, a long-distance migratory bird that has seen its population decline significantly in the British Isles and Northwestern Europe over the last century. Researchers found that these birds experienced a 34.8% loss in genetic diversity and an increase in inbreeding over the past 180 years, which could affect their ability to adapt to environmental changes. This is important because it indicates that declining populations may face greater risks in the future, not just in the UK but potentially across Europe.
Who this helps: This research benefits conservationists and wildlife biologists working to protect migratory bird species.
Acute Effects of Resistance Exercise on Intraocular Pressure in Healthy Adults: A Systematic Review.
2024
Journal of strength and conditioning research
Hackett DA, Li J, Wang B, Way KL, Cross T +1 more
Plain English This research looked at how resistance exercise affects the pressure inside the eyes (intraocular pressure, or IOP) in healthy adults under 55. The study found that during resistance exercises, IOP can rise significantly, with increases ranging from 3.1 to 28.7 mm Hg, especially when larger muscle groups are engaged, heavier weights are lifted, or breath-holding techniques are used. Most importantly, IOP generally returns to normal about one minute after exercise, which is crucial for understanding how physical activity impacts eye health.
Who this helps: This information is useful for doctors and patients concerned about eye pressure, particularly those with risk factors for glaucoma.
A Case Presentation of a Rare Pelvic Interdigitating Dendritic Cell Sarcoma.
2024
Cureus
Gordon TT, Cross T, Liu J
Plain English This study looked at a rare type of cancer called interdigitating dendritic cell sarcoma (IDCS) by sharing the case of a 34-year-old woman who was found to have a pelvic mass that turned out to be IDCS. The cancer was discovered by chance, as she had no obvious symptoms, and it was confirmed through a biopsy. Understanding these rare cancers is important because they can be difficult to diagnose, leading to delays in treatment.
Who this helps: This helps patients who may have rare cancers and their doctors in recognizing and managing these conditions.
COVID-19 booster enhances IgG mediated viral neutralization by human milk.
2024
Frontiers in nutrition
Valcarce V, Stafford LS, Neu J, Parker L, Vicuna V +11 more
Plain English This study investigated how a COVID-19 booster shot affects the levels of antibodies in the breast milk of vaccinated mothers and how these antibodies help fight the virus. The research found that after receiving the booster, mothers had a 90% increase in their blood's ability to neutralize the virus and a 60% increase in neutralization in their breast milk. This is important because it shows that booster vaccinations significantly strengthen the immune protection provided to infants through breastfeeding.
Who this helps: This helps breastfeeding mothers and their infants by enhancing immunity against COVID-19.
The effect of expiratory flow limitation on supine persistent hyperinflation in COPD: a prospective observational study.
2024
ERJ open research
Srinivasan M, Pollard H, Chapman DG, Tonga K, Patel K +6 more
Plain English This study looked at how lying down affects lung function in people with Chronic Obstructive Pulmonary Disease (COPD). It found that when COPD patients lay supine (on their backs), their lung inflation didn't improve compared to when they were seated, while healthy individuals saw improvements. Specifically, there was no significant change in lung capacity for 42 COPD patients, while 14 healthy subjects showed a notable increase in lung capacity when lying down. This matters because persistent lung hyperinflation in COPD can worsen symptoms like shortness of breath, especially while sleeping.
Who this helps: This benefits COPD patients by highlighting the challenges they face with lung function when lying down.
Healing of acute anterior cruciate ligament rupture on MRI and outcomes following non-surgical management with the Cross Bracing Protocol.
2023
British journal of sports medicine
Filbay SR, Dowsett M, Chaker Jomaa M, Rooney J, Sabharwal R +11 more
Plain English This study looked at how well the anterior cruciate ligament (ACL) heals in patients who had a rupture but did not have surgery, using a specific treatment called the Cross Bracing Protocol. The researchers found that 90% of the patients showed signs of healing on MRI after three months, with those showing more healing reporting better knee function and being able to return to their sport more often—92% of them were back in action compared to only 64% of those with less healing. This is important because it shows that non-surgical management of ACL injuries can be effective, helping many patients recover successfully.
Who this helps: This helps patients with ACL injuries and their doctors.
Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
2023
International journal of molecular sciences
Cross T, Haug KBF, Brusletto BS, Ommundsen SK, Trøseid AS +7 more
Plain English Researchers looked at the RNA found in tiny particles called extracellular vesicles in saliva from 11 patients with primary Sjögren's syndrome (pSS) and 11 healthy individuals. They discovered that 1,475 types of RNA were present in different amounts between the two groups, particularly noting that a specific type of RNA, tRNA-Ile-AAT-2-1, was half as abundant in pSS patients. This finding is important because it suggests that examining RNA in saliva could lead to easier and more accurate diagnosis of Sjögren's syndrome.
Who this helps: This helps patients with Sjögren's syndrome by providing a potential new way for doctors to diagnose their condition.
RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms.
2023
International journal of molecular sciences
Cross T, Øvstebø R, Brusletto BS, Trøseid AS, Olstad OK +5 more
Plain English This study looked at the RNA found in tiny particles from tears to see if it could help diagnose dry eye disease (DED) more effectively. Researchers collected tear samples from 10 patients and found that specific RNA types were significantly different between those with worse and better tear film stability, with one type of RNA being 3.8 times lower in patients with more severe symptoms. This matters because it suggests that testing tear fluid could simplify the way doctors diagnose and understand dry eye disease.
Who this helps: Patients suffering from dry eye symptoms.
Decreasing delivery room intubations: A quality improvement project.
2022
Journal of paediatrics and child health
Jardine L, Bates K, Bates A, Muirhead R, Bischoff E +13 more
Plain English This study looked at how to reduce the need for intubating premature babies (born before 32 weeks) in the delivery room, which can lead to breathing problems later on. Initially, about 48% of these babies required intubation, but after implementing a new method using bubble continuous positive airway pressure, that rate dropped to 28.2%. This is important because it shows a safer way to help these vulnerable babies breathe better right after birth, potentially leading to fewer complications.
Who this helps: This helps premature infants and their healthcare providers.
Role of club doctors in the mental health management of Australian rules football players: a Delphi study.
2022
British journal of sports medicine
Weber B, Bos J, Clancy EM, Menon R, Cross T +1 more
Plain English This study looked at how club doctors can better manage the mental health of Australian rules football players. It involved 28 doctors from professional AFL clubs who agreed on 77 important strategies for supporting athletes' mental health, with 50 of these receiving broad support from the doctors. This research is significant because it provides clear guidelines, helping to improve the way mental health issues are addressed in professional sports.
Who this helps: This benefits players, doctors, and mental health professionals working with athletes.
Adverse events following influenza immunization: understanding the role of age and sex interactions.
2022
Expert review of vaccines
Bohn-Goldbaum E, Cross T, Leeb A, Peters I, Booy R +1 more
Plain English This study looked at how age and sex affect the chances of experiencing side effects after getting the flu vaccine in Australia. Researchers found that 5.5% of people reported side effects, with women having higher odds of experiencing these between ages 30 and 70, while infants had higher odds among men. Understanding these trends can help improve vaccination by reducing side effects, especially for women in that age range.
Who this helps: This helps patients and healthcare providers by identifying higher-risk groups for vaccine side effects.
Murtha AN, Kazi MI, Schargel RD, Cross T, Fihn C +4 more
Plain English This study looked at how certain bacteria become tolerant to the antibiotic meropenem, which is crucial in treating infections. Researchers found that when exposed to meropenem, these bacteria modify their outer membranes to avoid damage, leading to a 10-fold increase in tolerance. This is important because it shows how bacteria can survive antibiotics, making infections harder to treat and contributing to antibiotic resistance.
Who this helps: This helps patients by informing doctors on how to treat bacterial infections more effectively.
Stray B, Lamb A, Kaushik A, Vovrosh J, Rodgers A +18 more
Plain English Researchers developed a new type of sensor that measures small changes in gravity more accurately and quickly than previous methods. This sensor was able to detect a 2-meter tunnel underground with great precision, achieving a high signal-to-noise ratio. The ability to gather this information faster and more accurately is important for applications like monitoring groundwater resources and assessing soil conditions, which can help prevent problems during construction projects.
Who this helps: This benefits engineers, environmental scientists, and archaeologists.
Rush or relax: migration tactics of a nocturnal insectivore in response to ecological barriers.
2022
Scientific reports
Lathouwers M, Artois T, Dendoncker N, Beenaerts N, Conway G +9 more
Plain English This research focused on how European Nightjars change their migration strategies depending on the types of landscapes they encounter. The study found that when flying through difficult areas (like ecological barriers), Nightjars flew faster and at higher altitudes at night, while in more hospitable places, they took their time, foraged more, and flew lower. Understanding these migration patterns is important for predicting how changes in land use could impact the birds' survival and their ability to refuel during migration.
Who this helps: This information benefits conservationists and wildlife managers working to protect migratory bird habitats.
Positive Indian Parenting: A Unique Collaborative Study in the Age of COVID-19.
2022
American Indian and Alaska native mental health research (Online)
Sahota PC, Contreras A, Kastelic S, Cross-Hemmer A, Ybarra Black A +5 more
Plain English This study looked at a parenting training program called Positive Indian Parenting (PIP) that has been used in Native American communities since the 1980s. Researchers found that during the COVID-19 pandemic, they had to adapt the program to deliver it online and collect data remotely. The study emphasizes the need for flexibility and teamwork to keep the program running in challenging times, which could help improve parenting skills in these communities.
Who this helps: This benefits Native American families and parents looking to enhance their parenting practices.
Associations between Serum 25-Hydroxyvitamin D Levels and Health-Related Quality-of-Life Measures in Patients with Breast Cancer: A Longitudinal Study.
2022
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cross T, George A, Attwood K, Zhang Y, O'Connor TL +5 more
Plain English This study looked at the relationship between vitamin D levels and quality of life in women who survived early-stage breast cancer. Researchers found that about 32% had low vitamin D levels when diagnosed, which decreased to 25% after one year. Women with inadequate vitamin D levels reported worse physical and mental health, indicating that vitamin D may improve well-being in breast cancer survivors.
Who this helps: This benefits breast cancer survivors seeking to enhance their health and quality of life.
Analytical evaluation and critical appraisal of early commercial SARS-CoV-2 immunoassays for routine use in a diagnostic laboratory.
2021
British journal of biomedical science
Cramer A, Goodman N, Cross T, Gant V, Dziadzio M
Plain English This study examined various antibody tests for the SARS-CoV-2 virus to find out which ones are best for diagnosing COVID-19 in mild and asymptomatic patients. The research found that the Roche test and Euroimmun tests had high accuracy, with sensitivities reaching up to 95.6% when combining different assays. This information is important because accurately detecting antibodies can help improve COVID-19 diagnostics and better understand immunity levels in the population.
Who this helps: Patients and healthcare providers.
A multifaceted cellular damage repair and prevention pathway promotes high-level tolerance to β-lactam antibiotics.
2021
EMBO reports
Shin JH, Choe D, Ransegnola B, Hong HR, Onyekwere I +6 more
Plain English Researchers studied how the bacterium Vibrio cholerae, which causes cholera, becomes tolerant to β-lactam antibiotics like penicillin. They found that the VxrAB system helps control iron levels in the cells; when this system is mutated, the bacteria become more tolerant to these antibiotics, allowing them to survive better under treatment. This matter because understanding how bacteria resist antibiotics can help develop better treatments and combat antibiotic resistance.
Who this helps: This helps patients, especially those suffering from cholera and other bacterial infections.
External validation of the Surgical Outcome Risk Tool (SORT) in 3305 abdominal surgery patients in the independent sector in the UK.
2021
Perioperative medicine (London, England)
Oakland K, Cosentino D, Cross T, Bucknall C, Dorudi S +1 more
Plain English This study looked at a tool called the Surgical Outcome Risk Tool (SORT), which predicts the risk of death within 30 days after major abdominal surgery. Researchers analyzed data from 3,305 patients and found that SORT effectively identified most lower-risk patients; however, it underestimated risks for high-risk patients, with only 2.18% labeled as high risk but experiencing a much higher rate of ICU admissions (25%) and deaths (3.3%) compared to those with a lower risk. This matters because accurately identifying high-risk patients can help doctors better prepare and manage their care after surgery.
Who this helps: This helps surgeons and healthcare providers working with patients undergoing major abdominal surgery.
Patient and family experience with transthyretin amyloid cardiomyopathy (ATTR-CM) and polyneuropathy (ATTR-PN) amyloidosis: results of two focus groups.
2021
Orphanet journal of rare diseases
Rintell D, Heath D, Braga Mendendez F, Cross E, Cross T +6 more
Plain English Researchers studied the experiences of patients and families dealing with transthyretin amyloidosis, a rare and difficult condition that affects the heart and nerves. They found that many patients faced long delays and confusion during the diagnosis process, often resulting in inadequate care. Specific symptoms varied between two groups – those with heart problems (ATTR-CM) struggled with fatigue and inability to exercise, while those with nerve issues (ATTR-PN) dealt with fatigue, bowel problems, and sensory issues. This matters because understanding these experiences can lead to better support and faster diagnoses for patients.
Who this helps: Patients and their families affected by ATTR.
30-Day postoperative COVID-19 outcomes in 398 patients from regional hospitals utilising a designated COVID-19 minimal surgical site pathway.
2021
Annals of the Royal College of Surgeons of England
Chong S, Hung R, Gwozdz A, Irwin S, Eastbury J +6 more
Plain English This study looked at the outcomes of 398 patients who had elective surgery during the COVID-19 pandemic while following strict safety protocols to minimize infection risks. The researchers found that only one patient died due to COVID-19 (0.25%), and there was a low overall death rate of 1.26% within 30 days after surgery. This shows that with proper screening, major surgeries can be performed safely even during the pandemic.
Who this helps: This helps patients undergoing elective surgeries and their healthcare providers.
Improving the quality of discharge summaries through a direct feedback system.
2020
Future healthcare journal
Earnshaw CH, Pedersen A, Evans J, Cross T, Gaillemin O +1 more
Plain English Researchers focused on improving how hospitals write discharge summaries, which are important documents that help patients and their doctors understand what care was provided during a hospital stay. They introduced a new feedback system, along with training for doctors, which led to a significant improvement in the quality of these summaries across several important areas. For instance, the summaries now better explain the patient's hospital stay and provide clearer instructions for follow-up care.
Who this helps: This helps patients, their families, and doctors by ensuring clear and effective communication after hospital discharge.
The Influence of Education and Specialty Certification on Nurses' Intent to Support Breastfeeding Post-Birth.
2020
The Journal of perinatal education
Cassar L, Bauley C, Friesen M, Brannon M, Brown L +2 more
Plain English This study examined how a nurse's education and specialty certification influence their willingness to help new mothers with breastfeeding after childbirth. The findings showed that nurses with higher education and specialty certifications are more likely to support breastfeeding—specifically, 60% of those with advanced training expressed strong intent to help, compared to only 30% of those without such credentials. This is important because increased nursing support can lead to better breastfeeding success, benefiting both mothers and their babies.
Who this helps: New mothers seeking to breastfeed.
What Does an Optimal District Standard For School Nursing Look Like?
2019
NASN school nurse (Print)
Cross T, Maughan ED, Mazyck D
Plain English This study focused on improving school nursing practices in the Mansfield Independent School District by creating a tool to assess and enhance the quality of health services provided to students and staff. The partnership with the National Association of School Nurses led to the development of a program that identifies effective practices, addressing challenges faced during implementation. The goal is to ensure that health services meet high standards, ultimately benefiting student health and academic success.
Who this helps: This benefits students and school nurses.
Intestinal ischemia due to methamphetamine use: A case report.
2019
International journal of surgery case reports
Choi K, Imrie A, Lourie R, Cross T
Plain English This study looked at a rare but serious complication of methamphetamine use: damage to the intestines due to lack of blood flow. In one case, a 48-year-old man experienced severe intestinal damage after using methamphetamine and required emergency surgery to remove the affected sections of his bowel. He recovered well after the surgery, highlighting the need for doctors to be alert to the possibility of intestinal problems in patients who use this drug.
Who this helps: This information helps doctors treating patients who use methamphetamine.
Increased multimodality treatment options has improved survival for Hepatocellular carcinoma but poor survival for biliary tract cancers remains unchanged.
2019
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Alabraba E, Joshi H, Bird N, Griffin R, Sturgess R +12 more
Plain English This study looked at the survival rates of patients with liver and bile duct cancers in the UK over eight years. It found that patients with Hepatocellular carcinoma (HCC) had better survival rates—about 900 days with curative treatment—compared to those with Cholangiocarcinoma and Gallbladder cancer, who had poorer outcomes of around 600 and 400 days, respectively. While the situation for HCC has improved thanks to new treatment options, the survival rates for Cholangiocarcinoma and Gallbladder cancer have not changed much and highlight a need for better therapies for these cancers.
Who this helps: This benefits patients with liver and bile duct cancers, especially those with HCC.
Spheroplast-Mediated Carbapenem Tolerance in Gram-Negative Pathogens.
2019
Antimicrobial agents and chemotherapy
Cross T, Ransegnola B, Shin JH, Weaver A, Fauntleroy K +3 more
Plain English This study examined how certain harmful bacteria can survive while being exposed to a strong antibiotic called meropenem, which is usually effective at killing them. The researchers found that various strains of Gram-negative bacteria showed moderate to high tolerance to the antibiotic, meaning they could keep living in its presence. Notably, this tolerance was due to a change in their shape that made them temporarily resistant, and they could return to normal growth once the antibiotic was removed. This is important because it highlights a potential reason why some antibiotic treatments fail.
Who this helps: This helps doctors treating infections caused by these resistant bacteria.
Validation of an algorithm using inpatient electronic health records to determine the presence and severity of cirrhosis in patients with hepatocellular carcinoma in England: an observational study.
2019
BMJ open
Driver RJ, Balachandrakumar V, Burton A, Shearer J, Downing A +3 more
Plain English This study focused on using hospital electronic health records to assess liver disease severity in patients diagnosed with hepatocellular carcinoma (HCC), a type of liver cancer. The researchers developed a system that accurately identifies cirrhosis, achieving a 99% accuracy for correctly diagnosing cirrhosis and 86% sensitivity overall. This is important because understanding the severity of liver disease can guide treatment decisions and improve patient outcomes.
Who this helps: This benefits doctors and patients with liver cancer by facilitating better treatment planning.
A survey of bolus tube feeding prevalence and practice in adult patients requiring home enteral tube feeding.
2019
The British journal of nutrition
Hubbard GP, Andrews S, White S, Simpson G, Topen S +19 more
Plain English A recent survey looked at how many adults on long-term home tube feeding use bolus feeding, which is a method that allows patients to eat larger amounts of nutrition at once. Out of 604 patients surveyed, 37% were using bolus feeding, and it was typically quick and convenient for them, with 85% also using oral nutritional supplements. This matters because it shows that bolus feeding is a popular option for many patients, helping them maintain a more normal eating routine while meeting their nutritional needs.
Who this helps: Patients needing home enteral tube feeding, especially those with conditions like head and neck cancer or cerebral palsy.
Ingested razor blades within the appendix: A rare case report.
2018
International journal of surgery case reports
Cui J, Cross T, Lockwood D
Plain English This study describes a unique case where a 25-year-old male prisoner ingested razor blades, which became stuck in his appendix. After trying conservative treatment for five days without improvement, doctors performed a surgery to safely remove the razor blades, which was successful and without complications. This case highlights the importance of understanding how foreign objects, even dangerous ones like razor blades, can end up in the appendix and be removed safely.
Who this helps: This helps doctors and healthcare providers manage similar cases of foreign body ingestion.
CyberKnife Radiosurgery of Skull-base Tumors: A UK Center Experience.
2018
Cureus
Wilson HP, Price PM, Ashkan K, Edwards A, Green MM +6 more
Plain English This study looked at how well the CyberKnife treatment works for patients with different types of tumors at the base of the skull. Out of 66 patients treated, those with specific benign tumors saw impressive results: 81% of patients with vestibular schwannomas and 83% of meningioma patients experienced no immediate side effects, while 100% had their tumors under control at follow-ups ranging from 11 to 22 months. These findings are important because they show that smaller tumors can be treated effectively with minimal harm, giving hope for improved outcomes in managing these conditions.
Who this helps: This helps patients with skull-base tumors and their doctors.
Tc-HMPAO-leukocyte scintigraphy for diagnosis and therapy monitoring of skull base osteomyelitis.
2018
Laryngoscope investigative otolaryngology
Rozenblum-Beddok L, Verillaud B, Paycha F, Vironneau P, Abulizi M +7 more
Plain English This study looked at a method called leukocyte scintigraphy (LS) to help diagnose and track the treatment of a serious infection called skull base osteomyelitis (SBO) in elderly diabetic patients. Out of 27 patients, 25 tested positive for infection when first diagnosed, and after treatment, 26 showed no signs of infection, indicating effective therapy. This technique is important because it helps doctors confirm when the infection has healed, which is crucial for managing this dangerous condition.
Who this helps: This helps patients with skull base osteomyelitis and their doctors.
A case report of a rare and challenging gangrenous splenic flexure volvulus in a pregnant patient.
2018
International journal of surgery case reports
Bullen A, Lewin J, Cross T, Woolven B
Plain English This research focused on a rare medical condition called splenic flexure volvulus, which can block the intestines. A 25-year-old pregnant woman experienced this condition but wasn't diagnosed until three days after she was admitted to the hospital, by which time her health had worsened. After urgent surgery, she recovered well and gave birth to her baby at full term, showing that prompt diagnosis and treatment are essential for both mother and child.
Who this helps: This helps pregnant women experiencing bowel obstructions and their healthcare providers.
Dose-Volume Histogram Analysis of Stereotactic Body Radiotherapy Treatment of Pancreatic Cancer: A Focus on Duodenal Dose Constraints.
2016
Seminars in radiation oncology
Goldsmith C, Price P, Cross T, Loughlin S, Cowley I +1 more
Plain English This study focused on how much radiation can safely be given to the duodenum (part of the small intestine) during stereotactic body radiotherapy (SBRT) for patients with difficult-to-treat pancreatic cancer. Researchers analyzed 44 patients and found that keeping the radiation dose to the duodenum below 31.4 Gy resulted in a low risk of serious complications, while higher doses increased the risk significantly—from 4.7% at 25.3 Gy to 20% at 37.4 Gy. This information is important because it helps doctors plan safer radiotherapy treatments that minimize damage to nearby organs, improving patient outcomes.
Who this helps: Patients with pancreatic cancer undergoing radiation therapy.