DR. VRIJESH SHANTANU TANTUWAYA, MD

POWAY, CA

Research Active
Neurological Surgery NPI registered 21+ years 1 publication 1995 – 1995 NPI: 1235134966
Neurological Surgery
RatsRats, Sprague-DawleyImmunohistochemistrySciatic NerveMembrane GlycoproteinsNerve Growth FactorsNerve Tissue ProteinsGAP-43 ProteinNeuropeptide Y

Practice Location

12630 MONTE VISTA RD
POWAY, CA 92064-2530

Phone: (858) 312-5016

What does VRIJESH TANTUWAYA research?

Dr. Tantuwaya studies how nerve injuries impact the body, specifically looking at the chemical changes that occur in response to such injuries. One of his main interests is a treatment known as neurotrophin-3 (NT-3), which has shown promise in reducing harmful responses in the spinal cord after a nerve injury. By understanding these processes, he aims to enhance recovery for patients suffering from various nerve injuries.

Key findings

  • Applying NT-3 near an injured sciatic nerve significantly reduced the increase of neuropeptide Y (NPY) in the spinal cord by a notable amount.
  • While NT-3 helped mitigate NPY-related responses, it did not affect the response of another chemical, CGRP, which is associated with nerve damage.
  • The findings suggest a potential pathway for improving recovery from nerve injuries, which may benefit patient outcomes.

Frequently asked questions

Does Dr. Tantuwaya study nerve injuries?
Yes, Dr. Tantuwaya focuses on nerve injuries and how different treatments can improve recovery.
What treatments has Dr. Tantuwaya researched?
He has researched the effects of neurotrophin-3 (NT-3) as a treatment for nerve injuries.
Is Dr. Tantuwaya's work relevant to patients with nerve damage?
Absolutely, his research aims to enhance recovery for patients suffering from nerve damage.
What chemical responses does Dr. Tantuwaya study?
He studies how chemicals like neuropeptide Y (NPY) and CGRP are affected by nerve injuries and treatments.

Publications in plain English

Exogenous NT-3 mitigates the transganglionic neuropeptide Y response to sciatic nerve injury.

1995

Brain research

Ohara S, Tantuwaya V, DiStefano PS, Schmidt RE

Plain English
This study looked at how a specific nerve injury affects certain chemicals in the body and tested a treatment using neurotrophin-3 (NT-3). Researchers found that applying NT-3 near the injured nerve reduced the increase of a chemical called neuropeptide Y (NPY) in the spinal cord by a significant amount, which helps protect nerve function after injury. However, this treatment didn’t change the response of another chemical called CGRP related to nerve damage. Who this helps: This benefits patients with nerve injuries by potentially improving their recovery.

PubMed

Frequent Co-Authors

S Ohara P S DiStefano R E Schmidt

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.