Dr. Ciszewski studies how different countries prioritize vaccinations during health crises, particularly looking at COVID-19. He investigates the immune system, specifically how certain substances affect immune cells and their responses to inflammation. Additionally, he explores how brain chemicals can protect brain cells during low oxygen levels, which is vital for conditions where the brain may suffer from a lack of oxygen, like strokes.
Key findings
In a study of 27 countries and regions during COVID-19, all prioritized older adults and those with health conditions over frontline workers for vaccination.
Exposure to d-lactate increased production of IL-4 and IL-13 proteins by nearly 30% in activated T lymphocytes at concentrations of 10-20 mM.
Orexin B was found to be more effective than orexin A in boosting the Akt protein, which supports cell survival during hypoxic stress.
Frequently asked questions
Does Dr. Ciszewski study COVID-19?
Yes, he examines how different countries prioritize COVID-19 vaccinations, especially for vulnerable populations.
What immune conditions does Dr. Ciszewski's research address?
His research addresses inflammatory conditions by studying how immune responses can be influenced by substances like d-lactate.
Is Dr. Ciszewski's work relevant to stroke patients?
Yes, his research on orexins aims to protect brain cells during low oxygen levels, which is critical for stroke patients.
What treatments or strategies has Dr. Ciszewski researched?
He has researched vaccination strategies for COVID-19 and potential treatments involving immune system modulation and brain cell protection.
Can Dr. Ciszewski's work help with gut issues?
Yes, his findings on T lymphocytes and d-lactate may provide insights into managing gut inflammation.
Publications in plain English
Value choices in European COVID-19 vaccination schedules: how vaccination prioritization differs from other forms of priority setting.
2022
Journal of law and the biosciences
Wiśniowska K, Żuradzki T, Ciszewski W
Plain English The study looked at how different countries in Europe and Israel prioritized COVID-19 vaccinations when there were limited supplies in early 2021. It found that all of the 27 countries and regions studied chose to prioritize older people and those with health conditions (who have a higher risk of dying from the virus) over groups at higher risk of infection, such as frontline workers. This is notable because, in typical medical treatment situations, different criteria might be used to decide who gets treatment first.
Who this helps: This helps policymakers determine vaccination strategies to protect vulnerable populations effectively.
Lactate Stimulates IL-4 and IL-13 Production in Activated HuT-78 T Lymphocytes Through a Process That Involves Monocarboxylate Transporters and Protein Hyperacetylation.
2016
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Wagner W, Ciszewski W, Kania K, Dastych J
Plain English This study looked at how a substance called d-lactate affects immune cells, specifically T lymphocytes, which are important for the body's immune response. Researchers found that exposing these cells to d-lactate increased the production of two important proteins—IL-4 and IL-13—by nearly 30% in some cases when exposed to 10-20 mM concentrations. This is significant because it shows how local bacteria in the gut can influence immune responses, potentially helping reduce inflammation.
Who this helps: This research benefits patients with inflammatory conditions, including gut and reproductive tract issues, by providing insights into how their immune responses can be modulated.
Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling.
2014
Journal of molecular neuroscience : MN
Sokołowska P, Urbańska A, Biegańska K, Wagner W, Ciszewski W +2 more
Plain English The study looked at how two brain chemicals, orexin A and orexin B, help protect brain cells from damage caused by low oxygen levels. The researchers found that these orexins significantly boost a protein called Akt, which supports cell survival. Specifically, orexin B was more effective than orexin A, but both were similar in their overall impact. This is important because it helps us understand how to protect brain cells during oxygen deprivation, which could improve treatments for conditions like stroke.
Who this helps: This helps patients at risk of brain damage due to hypoxia, such as those experiencing strokes or respiratory distress.
[The duty of professional secrecy--the law of professional secrecy. Interpretation of paragraph 300 of the Penal Code with special reference to the physician in public health service].
B Lazarkiewicz W Sawicz Tomasz Żuradzki Waldemar Wagner Karolina Wiśniowska Katarzyna Kania Jarosław Dastych Paulina Sokołowska Anna Urbańska Kaja Biegańska
Physician data sourced from the
NPPES NPI Registry
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Publication data from
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Plain-English summaries generated by AI.
Not medical advice.