Dr. Mondal studies the effects of various medical conditions and treatments on patients undergoing kidney and pancreas transplants. He has investigated how different types of diabetes impact outcomes after simultaneous pancreas-kidney transplantation, ensuring that care protocols can be effectively standardized. His work also evaluates how conditions like coronary artery disease, obesity, and high blood flow in dialysis access devices affect transplant success and patient health. Through his research, he seeks to develop tools and strategies to improve patient selection and monitoring for transplant candidates.
Key findings
In pancreas-kidney transplantation, glucose levels and insulin use were nearly identical between patients with type 1 and type 2 diabetes, indicating that a single care protocol is effective for both.
When blood flow through arteriovenous (AV) fistulas exceeds 1.5-2 liters per minute, patients face higher risks of heart enlargement, high-output heart failure, and pulmonary hypertension, emphasizing the need for regular monitoring.
In a study of 225 kidney transplant candidates, 47% had significant coronary artery disease, yet 65% of prior stress tests failed to detect it, highlighting the reliability of coronary angiography.
The Kidney Transplant Morbidity Index (KTMI) predicts that each point increase in its score correlates with worse 3-year graft and patient survival, providing an accessible tool for clinicians.
Posttransplant amputation led to nearly triple the all-cause mortality and shorter graft survival compared to those without amputation, underscoring the importance of early detection of vascular disease.
Frequently asked questions
Does Dr. Mondal study diabetes?
Yes, he researches the effects of type 1 and type 2 diabetes on outcomes following pancreas-kidney transplantation.
What tools has Dr. Mondal developed for kidney transplant candidates?
He developed the Kidney Transplant Morbidity Index (KTMI), a scoring tool that predicts patient and graft survival based on existing health conditions.
Is Dr. Mondal's research relevant for dialysis patients?
Yes, he examines the effects of dialysis access on heart and lung health, which is critical for dialysis patients.
How does obesity affect kidney transplant candidates?
His research indicates that while morbid obesity leads to longer hospital stays, it may not be as significant a risk factor for candidacy as other health issues.
What impact does amputation have on kidney transplant outcomes?
Amputation post-transplant is associated with substantially shorter graft survival and higher mortality rates, making early detection of related issues vital.
Publications in plain English
Immediate Glycemic Outcomes Following Simultaneous Pancreas-Kidney Transplantation: Equivalent Early Metabolic Profiles in Type 1 and Type 2 Diabetes.
2026
Cureus
Jalalzadeh M, Mondal Z, Hashmi N, Bunin S, Shah M +6 more
Plain English Researchers compared how well a transplanted pancreas works in the first month after surgery in patients with two different types of diabetes—type 1 and type 2. They found that blood sugar levels, insulin requirements, and overall graft success were virtually identical between the two groups, despite type 2 patients being older and heavier while type 1 patients had had diabetes much longer.
This matters because it shows doctors can safely use the same surgical approach and post-surgery care protocols for both diabetes types, expanding who can benefit from this life-changing transplant procedure.
Hemodialysis Access Blood Flow and Cardiopulmonary Outcomes.
2025
Cureus
Mondal Z, Jalalzadeh M, Khalil S
Plain English Arteriovenous fistulas and grafts created for hemodialysis access redirect large volumes of blood through the heart, which can cause long-term cardiac strain. This review synthesizes how dialysis access blood flow affects heart structure and function, and when intervention is warranted. Understanding these hemodynamic effects is critical to preventing heart failure in dialysis-dependent patients.
Role of Coronary Angiography in the Assessment of Cardiovascular Risk in Kidney Transplant Candidates.
2016
The American journal of cardiology
Mann DM, Fernandez S, Mondal Z, Laskow D, Osband A +7 more
Plain English This study evaluated whether standard nuclear stress tests reliably detect coronary artery disease in kidney transplant candidates. Among 225 high-risk patients who underwent coronary angiography, 47% had significant disease, but 65% of their preceding stress tests were falsely negative. Coronary angiography with revascularization when needed reduced mortality both on the waiting list and after transplant.
The Kidney Transplant Morbidity Index (KTMI): a simple prognostic tool to help determine outcome risk in kidney transplant candidates.
2015
Progress in transplantation (Aliso Viejo, Calif.)
Pieloch D, Dombrovskiy V, Osband AJ, DebRoy M, Mann RA +3 more
Plain English Researchers developed the Kidney Transplant Morbidity Index (KTMI), a simple pretransplant scoring tool that predicts graft and patient survival using known comorbidities. Analysis of over 100,000 transplants showed that each point increase on the KTMI score corresponded to meaningfully worse 3-year graft and patient survival. The KTMI gives clinicians an easy-to-use tool to quantify outcome risk before placing a patient on the transplant list.
The impact of morbid obesity on hospital length of stay in kidney transplant recipients.
2014
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation
Pieloch D, Mann R, Dombrovskiy V, DebRoy M, Osband AJ +3 more
Plain English Using national data, researchers compared hospital length of stay after kidney transplant between morbidly obese and normal-weight recipients. While morbidly obese patients had higher crude rates of prolonged stays, multivariate analysis showed that obesity was no stronger a predictor than being African American, having diabetes, or having coronary artery disease. Morbid obesity alone should not drive decisions about kidney transplant candidacy based on hospital cost concerns.
Impact of renal posttransplantation amputation on allograft outcomes: a study of United States renal data system.
2013
Transplantation
Brar A, Jindal RM, Sumrani N, John D, Mondal Z +2 more
Plain English This study examined how amputation after kidney transplantation affected graft and patient survival using a large national dataset. Recipients who underwent posttransplant amputation had meaningfully shorter mean graft survival and nearly triple the all-cause mortality compared to those without amputation. Early detection and prevention of peripheral vascular disease in transplant candidates and recipients is critical to improving long-term outcomes.
Sonalis Fernandez Mojgan Jalalzadeh Steve Khalil Richard A Mann Daniel Pieloch Viktor Dombrovskiy Adena J Osband Meelie DebRoy David A Laskow Nooruddin Hashmi
Physician data sourced from the
NPPES NPI Registry
.
Publication data from
PubMed
.
Plain-English summaries generated by AI.
Not medical advice.