Antonio Cocchiaro

Department of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.

3 publications 2021 – 2023
Angioedemas, HereditaryComplement C1 Inhibitor ProteinAngioedemaGenitaliaDelayed Diagnosis

What does Antonio Cocchiaro research?

Antonio Cocchiaro studies how the mRNA vaccines for COVID-19 affect individuals with hereditary angioedema, a condition characterized by unexpected swelling episodes. His research specifically looks at whether these vaccines can trigger more attacks or have any negative effects on these patients. Notably, he investigates how the vaccinations impact the patients' overall health and if they help control the condition better.

Key findings

  • In a study of 31 patients with hereditary angioedema, the COVID-19 vaccine did not increase the frequency of swelling attacks, showing it is safe for this group.
  • Following vaccination, all participants developed protective antibodies against COVID-19, comparable to healthy individuals.
  • Patients reported improved control of their hereditary angioedema symptoms after receiving the vaccine.

Frequently asked questions

Does Dr. Cocchiaro study hereditary angioedema?
Yes, he specializes in research related to hereditary angioedema and how vaccinations affect patients with this condition.
What treatments has Dr. Cocchiaro researched?
He has researched the safety and efficacy of mRNA COVID-19 vaccines in patients with hereditary angioedema.
Is Dr. Cocchiaro's work relevant to COVID-19 immunization for patients with rare conditions?
Yes, his studies provide important insights into how COVID-19 vaccines can safely protect patients with rare conditions like hereditary angioedema.

Publications in plain English

Immunogenicity and Safety of Anti-SARS-CoV-2 mRNA Vaccines in a Cohort of Patients with Hereditary Angioedema.

2023

Vaccines

Mormile I, Gigliotti MC, Petraroli A, Cocchiaro A, Furno A +4 more

Plain English
Researchers gave 31 patients with hereditary angioedema (a rare condition causing sudden swelling attacks) two doses of the Pfizer COVID-19 vaccine to see if the shots would trigger more attacks or cause problems. While a few patients did have swelling attacks shortly after the first shot, the vaccine did not increase attack frequency overall, and patients' disease control actually improved after vaccination. All vaccinated patients developed protective antibodies against COVID-19 just like healthy people did, confirming the vaccine worked in this population.

PubMed

Clinical features and burden of genital attacks in hereditary angioedema.

2022

The journal of allergy and clinical immunology. In practice

Mormile I, Bova M, Cocchiaro A, Rossi FW, Granata F +3 more

PubMed

Gastrointestinal manifestations of angioedema: a potential area of misdiagnosis.

2021

European journal of gastroenterology & hepatology

Mormile I, Cocchiaro A, Bova M, Loffredo S, de Paulis A +2 more

Plain English
This study looked at abdominal pain caused by a rare condition called angioedema, which can affect the gastrointestinal tract. It found that in people with hereditary angioedema, 43-93% experience abdominal pain, often for many years, without any other symptoms like skin rashes or breathing issues. Recognizing this connection is crucial because it can prevent misdiagnoses and help avoid unnecessary medical procedures, leading to better treatment and less suffering for patients. Who this helps: This benefits patients experiencing unexplained abdominal pain and their doctors.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.