CHARLOTTE WILLIS, MD

LITTLE ROCK, AR

Research Active
Pediatrics - Pediatric Emergency Medicine NPI registered 20+ years 18 publications 1967 – 2026 NPI: 1619067279

Practice Location

800 MARSHALL ST # 653
LITTLE ROCK, AR 72202-3510

Phone: (501) 364-1100

What does CHARLOTTE WILLIS research?

C B Willis studies the rich biodiversity of fungi, specifically large mushrooms, in subtropical environments. His work involves cataloging various fungal species at a nature preserve in Florida, where he identified over 546 distinct types of fungi through rigorous sampling and DNA testing. This research is crucial because fungi play a vital role in forest ecosystems by aiding in nutrient absorption for trees and breaking down organic matter. Understanding the diversity of fungi is just as important as studying plants and animals, but it has been less explored, making Willis's work particularly significant for ecological awareness and conservation efforts.

Key findings

  • Identified over 546 species of fungi at the Florida nature reserve, with an estimated total of 900 to 1,200 species present.
  • Established that the number of fungal species at this site exceeds the combined total of vertebrate animals and plants.
  • Utilized DNA testing techniques to accurately identify each fungal specimen, creating a reference collection for future research.

Frequently asked questions

Does Dr. Willis study fungi?
Yes, Dr. Willis focuses on the biodiversity of fungi, especially mushrooms, at subtropical sites.
What techniques does Dr. Willis use in his research?
He uses DNA testing to accurately identify different species of fungi, ensuring precise cataloging.
Why is Dr. Willis's research important?
His work helps understand the critical role fungi play in ecosystems, which is essential for conservation and ecological health.
Is Dr. Willis's work relevant to environmental conservation?
Absolutely, his findings contribute to better awareness and protection of biodiversity in subtropical ecosystems.
What kind of species has Dr. Willis discovered?
He has discovered a wide variety of mushroom species, with estimates suggesting that many more remain to be documented.

Publications in plain English

Femoral tunnel reaming method in anterior cruciate ligament reconstruction cannot be determined from plain radiographs alone.

2026

Annals of joint

Burnham JM, Drazick AT, Veillon-Bradshaw M, Aminake G, Schoondyke J +2 more

Plain English
This study looked at how well surgeons can determine the method used to create a tunnel during ACL surgery by looking at standard X-rays taken after the operation. Researchers found that surgeons only correctly identified the reaming method 64% of the time, and their accuracy was low, indicating that X-rays alone are not reliable for this purpose. This is important because it warns doctors not to jump to conclusions about surgery failures based on poor tunnel placement as judged from X-rays alone. Who this helps: This helps surgeons and their patients understand the limitations of using X-rays for assessing surgical techniques.

PubMed

Pediatric orthopedic all-terrain vehicle injury patterns, surgeries, and complications: appreciating the true morbidity and impact.

2025

Journal of pediatric orthopedics. Part B

Willis CB, Rabenhorst BM, Johnston K, Bumpass DB

Plain English
This study looked at the injuries caused by all-terrain vehicle (ATV) accidents in children, focusing on the types of fractures, surgeries needed, and complications. Researchers found that nearly half of the 489 patients treated suffered orthopedic injuries; 63% of these kids needed surgery, and 22% had to undergo multiple operations. The high rates of surgery for certain types of fractures suggest a serious need for better safety measures and education about ATV use. Who this helps: This research benefits parents, pediatricians, and safety advocates by highlighting the risks associated with ATV use in children.

PubMed

Think globally, barcode locally: nine years of macrofungi sampling reveals extensive biodiversity at the ordway-swisher biological station, a subtropical site in Florida.

2025

Fungal biology

Caiafa MV, Kaminsky L, Healy R, Sheffer LP, Willis CB +26 more

Plain English
Researchers spent nine years cataloging mushrooms and other large fungi at a Florida nature preserve, identifying over 546 species and estimating the actual total is probably between 900 and 1,200 species—meaning there are more fungal species at this one site than there are vertebrate animals or plants. They used DNA testing to precisely identify each specimen and created a reference collection for future research. This matters because fungi are essential to forest ecosystems (they help trees absorb nutrients and break down dead material), yet scientists know far less about fungal diversity than they do about plants and animals, making this comprehensive catalog a crucial foundation for understanding and protecting Florida's ecosystems.

PubMed

Tibiotalocalcaneal Arthrodesis with Intramedullary Fibular Strut Graft and Adjuvant Hardware Fixation.

2023

JBJS essential surgical techniques

Sankey M, Sanchez T, Young SM, Willis CB, Harrelson A +1 more

Plain English
This study looked at a surgical method for treating patients with severe damage to their ankle area, where traditional approaches had failed. Using a fibular strut autograft, the researchers achieved a bone healing rate of about 81%, comparable to traditional methods (which healed between 74% and 90% of the time), along with a significant reduction in pain from an average score of 6.9 to 1.2 after the procedure. This approach offers a reliable option for patients who have already had unsuccessful surgeries and need relief from pain to improve their daily activities. Who this helps: This helps patients with chronic foot pain, especially those with past surgical failures.

PubMed

Achilles Tendon Rupture Repair Using the Mini-Open Approach in a Supine Position.

2023

JBJS essential surgical techniques

Sanchez TC, Sankey MT, Willis CB, Young SM, Harrelson A +1 more

Plain English
This study looked at a new way to repair ruptured Achilles tendons using a mini-open technique with patients lying on their backs instead of their stomachs. Researchers found that this method had a lower complication rate (7.7%) compared to the traditional approach (9.3%), and it also saved about $1,823 on average in costs associated with surgery. This matters because it offers a safer and more cost-effective option for treating Achilles tendon injuries without compromising the quality of the repair. Who this helps: This benefits patients with Achilles tendon ruptures by providing them with safer and more affordable treatment options.

PubMed

Radial-to-Axillary Nerve Transfer Resolves Symptoms of Axillary Nerve Injury Due to Proximal Humerus Fracture-Dislocation in an Elderly Patient Treated With Hemiarthroplasty.

2019

Orthopedics

Willis CB, Ahmadi S

Plain English
This study looked at an elderly patient with a complex shoulder injury that caused damage to the axillary nerve, affecting shoulder function. After treating the injury with a type of shoulder replacement surgery, the doctors performed a special nerve surgery to connect another nerve to the axillary nerve because the patient’s shoulder didn’t improve on its own. This approach led to significant recovery in shoulder function, demonstrating that nerve transfer can effectively help patients with similar injuries. Who this helps: This benefits elderly patients recovering from shoulder injuries due to fractures.

PubMed

Bactericidal activity of starch-encapsulated gold nanoparticles.

2013

Frontiers in bioscience (Landmark edition)

Pender DS, Vangala LM, Badwaik VD, Willis CB, Aguilar ZP +3 more

Plain English
This study looked at how eco-friendly gold nanoparticles wrapped in starch can kill bacteria. The researchers found that a dose of 1.2 mg/mL of these nanoparticles eliminated 98% of Gram-positive bacteria, while 4.8 mg/mL was necessary for the same result with Gram-negative bacteria, both over a 12-hour period. This is important because it shows a new way to effectively fight bacterial infections using a safe and natural material. Who this helps: This benefits patients by providing a new treatment option for bacterial infections.

PubMed

Antibacterial gold nanoparticles-biomass assisted synthesis and characterization.

2013

Journal of biomedical nanotechnology

Badwaik VD, Willis CB, Pender DS, Paripelly R, Shah M +4 more

Plain English
This study explored how to create gold nanoparticles using xylose, a natural sugar found in materials like straw and corn cobs, in an eco-friendly way. The researchers made stable nanoparticles that are about 15 nanometers wide and found they effectively kill bacteria, including E. coli and Staphylococcus epidermidis, with their antibacterial effectiveness increasing with higher concentrations. This is important because these green gold nanoparticles could lead to new antibacterial treatments in healthcare. Who this helps: Patients who need better antibacterial treatments.

PubMed

Size-dependent antimicrobial properties of sugar-encapsulated gold nanoparticles synthesized by a green method.

2012

Nanoscale research letters

Badwaik VD, Vangala LM, Pender DS, Willis CB, Aguilar ZP +3 more

Plain English
This study looked at how different sizes of gold nanoparticles coated in sugar can kill bacteria. The researchers found that these sugar-coated gold nanoparticles significantly inhibited bacterial growth, showing that larger particles (like those averaging 120 nm) were more effective at harming bacteria than smaller ones. This is important because it suggests that these green-synthesized nanoparticles could be used as a new way to prevent and treat infections caused by harmful bacteria. Who this helps: This benefits patients who are at risk of bacterial infections.

PubMed

Single-step biofriendly synthesis of surface modifiable, near-spherical gold nanoparticles for applications in biological detection and catalysis.

2011

Langmuir : the ACS journal of surfaces and colloids

Badwaik VD, Bartonojo JJ, Evans JW, Sahi SV, Willis CB +1 more

Plain English
This study focused on creating gold nanoparticles (tiny gold particles) in a simple and environmentally friendly way. Researchers developed a method using dextrose, which allowed them to produce stable gold nanoparticles that are 10-120 nanometers in size, making them suitable for use in biological detection and other applications. This method is significant because it simplifies the process of incorporating these nanoparticles into living systems, such as bacteria, which can enhance their usefulness in medical and scientific settings. Who this helps: This helps researchers and scientists working in medicine and biotechnology.

PubMed

Anatomic anomalies and carpal tunnel syndrome: a review.

1999

Techniques in hand & upper extremity surgery

Willis CB, Alderman A, Louis DS

PubMed

Influence of Soil Temperature and pH on Pratylenchus Penetrans and P. crenatus in Alfalfa and Timothy.

1981

Journal of nematology

Kimpinski J, Willis CB

Plain English
This study looked at how soil temperature and acidity (pH) affect two types of tiny roundworms, Pratylenchus penetrans and P. crenatus, that live in alfalfa and timothy grass. Researchers found that warmer temperatures (from about 10°C to 30°C) led to a big increase in P. penetrans, but for P. crenatus in alfalfa, higher temperatures actually decreased their numbers. Raising the soil acidity from 5.0 to 6.9 increased P. penetrans in alfalfa but reduced P. crenatus significantly, showing how soil conditions can influence these pests’ populations. Who this helps: This helps farmers growing alfalfa and timothy grass by informing them on how to manage soil conditions for better crop health.

PubMed

Effects of Phenamiphos, Methyl Bromide, and Fallowing on Pratylenchus Penetrans, Yield of Medicago sativa, and Fusarium Infections.

1979

Journal of nematology

Willis CB, Thompson LS

Plain English
Researchers studied the impact of two chemicals (phenamiphos and methyl bromide) and a farming practice called fallowing on a harmful pest (root lesion nematodes) and diseases in alfalfa plants. They found that while fallowing helped control nematodes initially, after two years, their numbers returned to high levels. Methyl bromide was the most effective treatment, leading to a 34% increase in alfalfa yield over four years, highlighting how much microorganisms can harm crop production. Who this helps: This benefits farmers and agricultural producers who grow alfalfa.

PubMed

Effects of potassium fertilization and Pratylenchus penetrans on yield and potassium content of red clover and alfalfa.

1976

Journal of nematology

Willis CB

Plain English
This study looked at how adding potassium fertilizer and the presence of a specific plant pest, Pratylenchus penetrans, affected the growth and potassium levels in red clover and alfalfa. Researchers found that while potassium generally boosted crop yields, the nematode infection reduced yields overall; for example, red clover and alfalfa plants yielded less due to the pest, especially when potassium levels were higher. This matters because managing potassium levels can help farmers maximize their crop yields, even in the presence of nematode pests. Who this helps: Farmers growing red clover and alfalfa.

PubMed

Efficacy of multiple applications of oxamyl and phenamiphos for control of Pratylenchus penetrans in birdsfoot trefoil.

1976

Journal of nematology

Thompson LS, Willis CB

Plain English
This study looked at how two pesticides, oxamyl and phenamiphos, help control a type of harmful worm called Pratylenchus penetrans in birdsfoot trefoil, a type of plant. Researchers found that applying phenamiphos before planting substantially reduced the worm population in the soil and roots, boosting forage yields the following season. However, using oxamyl did not consistently increase the plant's yields, and both treatments failed to prevent declines in plant stands over time. Who this helps: This research benefits farmers growing birdsfoot trefoil by providing information on pest control options.

PubMed

Effects of Soil pH on Reproduction of Pratylenchus penetrans and Forage Yield of Alfalfa.

1972

Journal of nematology

Willis CB

Plain English
This study looked at how different soil acidity levels (pH) affect a type of nematode, Pratylenchus penetrans, and how that impacts alfalfa growth. Researchers found that the nematodes reproduced more in soils with pH levels of 5.2 and 6.4, which led to reduced alfalfa yields, while the crop thrived in very acidic (4.4) or very alkaline (7.3) soils. This is important because knowing the best soil conditions can help farmers improve alfalfa production despite nematode issues. Who this helps: Farmers growing alfalfa.

PubMed

Effect of various nitrogen sources on growth of Sclerotinia.

1968

Canadian journal of microbiology

Willis CB

PubMed

Effect of various carbon sources on growth of Sclerotinia trifoliorum.

1967

Canadian journal of microbiology

Willis CB

PubMed

Frequent Co-Authors

Chad B Willis Vivek D Badwaik Rajalingam Dakshinamurthy Dillon S Pender Rammohan Paripelly Lakshmisri M Vangala Sean M Young Alex Harrelson Matthew S Gonzalez Zoraida P Aguilar

Physician data sourced from the NPPES NPI Registry . Publication data from PubMed . Plain-English summaries generated by AI. Not medical advice.