C Pintus

Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), Università degli Studi di Palermo, Piazza delle Cliniche 2, Via del Vespro 129, 90127, Palermo, Italy.; Internal Medicine and Stroke Care Ward, University Hospital, Policlinico "P. Giaccone", Palermo, Italy.

50 publications 1995 – 2025

What does C Pintus research?

C Pintus studies how faecal microbiota transplantation (FMT) can be used to treat various gut-related disorders, especially infections. FMT involves transferring healthy gut bacteria from a donor to a patient to restore balance in their digestive system. This research is particularly relevant for individuals suffering from chronic infections or conditions that alter gut health, as it aims to provide a new treatment option that could improve their quality of life.

Key findings

  • The consensus conference involved 28 experts from 10 countries, indicating a strong international interest and collaboration in this field.
  • Faecal microbiota transplantation (FMT) is recognized as a promising treatment for gut disorders, highlighting its potential benefits for patients.
  • Recommendations from the study aim to standardize procedures for FMT, ensuring safety and effectiveness in clinical practice.

Frequently asked questions

Does Dr Pintus study gut-related disorders?
Yes, Dr Pintus focuses on gut-related disorders, particularly how faecal microbiota transplantation (FMT) can be used to treat these conditions.
What treatments has Dr Pintus researched?
Dr Pintus has researched faecal microbiota transplantation (FMT) as a treatment for infections and other disorders of the gut.
Is Dr Pintus's work relevant to patients with chronic infections?
Yes, their research provides insights and potential treatment options for patients suffering from chronic gut infections.

Publications in plain English

Mortality and recurrence in acute ischemic stroke of all etiologies according to ultrasonographic assessment of carotid and aortic arch plaques: a prospective study.

2025

Internal and emergency medicine

Miceli G, Basso MG, Casuccio A, Pennacchio AR, Cocciola E +5 more

Plain English
This study looked at how ultrasound pictures of the neck and heart arteries could predict if stroke patients would have a repeat stroke or die within three years. Researchers examined 108 patients who had their first stroke and found that those without plaque in their arteries had better survival rates, while those with plaque in both neck arteries faced higher risk of death. This is important because it shows that simple ultrasound tests can help doctors identify patients who are at greater risk after a stroke and guide better care. Who this helps: Patients who have had a stroke and their doctors.

PubMed

Paraneoplastic Cerebellar Degeneration Associated with Breast Cancer: A Case Report and a Narrative Review.

2024

Brain sciences

Norrito RL, Puleo MG, Pintus C, Basso MG, Rizzo G +4 more

Plain English
This study explored a rare complication of breast cancer called paraneoplastic cerebellar degeneration, which affects the nervous system. Researchers presented a case of a young woman who developed muscle stiffness, difficulty walking, and double vision due to this condition linked to her breast tumor. Recognizing these symptoms early is important because it can improve treatment outcomes. Who this helps: This benefits patients with breast cancer and their doctors by highlighting the need for awareness of neurological symptoms related to cancer.

PubMed

Molecular Pathways of Vulnerable Carotid Plaques at Risk of Ischemic Stroke: A Narrative Review.

2024

International journal of molecular sciences

Miceli G, Basso MG, Pintus C, Pennacchio AR, Cocciola E +4 more

Plain English
This study looked at the features of vulnerable carotid plaques, which can lead to strokes, especially in people with artery hardening. Researchers found that certain characteristics, such as having a thin protective layer and signs of inflammation, increase the risk of plaque rupture, even when there’s not a significant blockage (less than 50%). Understanding these features helps predict strokes better and identify patients at higher risk. Who this helps: This benefits patients at risk of stroke and their doctors by improving risk assessment and treatment strategies.

PubMed

The Impact of Malnutrition on Chronic Obstructive Pulmonary Disease (COPD) Outcomes: The Predictive Value of the Mini Nutritional Assessment (MNA) versus Acute Exacerbations in Patients with Highly Complex COPD and Its Clinical and Prognostic Implications.

2024

Nutrients

Di Raimondo D, Pirera E, Pintus C, De Rosa R, Profita M +3 more

Plain English
This study looked at how malnutrition affects older patients with Chronic Obstructive Pulmonary Disease (COPD) and their risk of worsening symptoms over a year. Out of 120 patients, 32.5% were in good nutritional health, while 47.5% were at risk of malnutrition and 20% were malnourished. The researchers found that malnourished patients were significantly more likely to experience severe flare-ups of their COPD, with malnourished patients having a nearly five times higher risk of worsening symptoms compared to those with good nutrition. Who this helps: This helps elderly COPD patients by highlighting the importance of monitoring their nutritional health to improve outcomes.

PubMed

Chest Pain: Wellens Syndrome Due to Spontaneous Dissection of the Left Anterior Descending Coronary Artery - A Case Report and Literature Review.

2024

Reviews in cardiovascular medicine

Clemente G, Quaranta C, Basso MG, Pintus C, Rizzo G +8 more

Plain English
This study examined a case of Wellens syndrome, a specific heart condition often related to temporary blockages in the coronary arteries, caused here by a rare event known as spontaneous coronary artery dissection (SCAD). The patient experienced chest pain and showed changes in heart activity on an ECG that matched Wellens syndrome, with slight elevations in heart damage markers, but these issues resolved by the time they reached the hospital. Understanding conditions like this is crucial because timely recognition can help prevent serious heart damage and improve outcomes for patients. Who this helps: This information benefits patients with unexplained chest pain and doctors diagnosing heart conditions.

PubMed

The Potential Impact of SGLT2-I in Diabetic Foot Prevention: Promising Pathophysiologic Implications, State of the Art, and Future Perspectives-A Narrative Review.

2024

Medicina (Kaunas, Lithuania)

Miceli G, Basso MG, Pennacchio AR, Cocciola E, Pintus C +5 more

Plain English
This research paper examines the impact of SGLT2 inhibitors (SGLT2-i), a type of medication for diabetes, on preventing diabetic foot problems. The study highlights that these drugs show promise in addressing issues linked to diabetic foot, such as inflammation and blood vessel health, but there's a lack of strong evidence from long-term studies confirming their effectiveness for this specific use. This matters because diabetic foot complications can lead to serious outcomes like amputations, which place a heavy burden on patients and healthcare systems. Who this helps: This helps patients with diabetes, particularly those at risk of developing foot problems.

PubMed

Heart rate variability is associated with disease severity and portal hypertension in cirrhosis.

2023

Hepatology communications

Miceli G, Calvaruso V, Casuccio A, Pennisi G, Licata M +12 more

Plain English
Researchers looked at how heart rate variability (HRV), a measure of the autonomic nervous system, relates to the severity of liver disease and portal hypertension in patients with cirrhosis. They studied 157 patients with cirrhosis and found that a specific HRV measurement (called SDANN) was lower in patients with more severe liver dysfunction and larger esophagogastric varices. This is important because it shows that changes in the autonomic nervous system are linked to worsening liver disease and portal hypertension, which could help in monitoring and treating affected patients. Who this helps: This helps doctors and patients with liver disease.

PubMed

Artificial Intelligence in Acute Ischemic Stroke Subtypes According to Toast Classification: A Comprehensive Narrative Review.

2023

Biomedicines

Miceli G, Basso MG, Rizzo G, Pintus C, Cocciola E +2 more

Plain English
This study examined how artificial intelligence (AI) can help doctors identify the cause of ischemic strokes, which are brain blockages that can lead to serious health issues. The research found that AI tools can significantly improve the detection of stroke causes, especially in patients who have undetermined reasons for their strokes, by accurately analyzing various medical images and data. This is important because understanding the specific cause of a stroke allows for faster and more effective treatment, which can prevent further brain damage. Who this helps: Patients who suffer from strokes and their doctors.

PubMed

The Role of the Cumulative Illness Rating Scale (CIRS) in Estimating the Impact of Comorbidities on Chronic Obstructive Pulmonary Disease (COPD) Outcomes: A Pilot Study of the MACH (Multidimensional Approach for COPD and High Complexity) Study.

2023

Journal of personalized medicine

Di Raimondo D, Pirera E, Pintus C, De Rosa R, Profita M +3 more

Plain English
This study looked at how well the Cumulative Illness Rating Scale (CIRS) can help predict the risk of serious flare-ups in patients with chronic obstructive pulmonary disease (COPD) who also have other health problems. Researchers found that a higher CIRS score was linked to an increased risk of moderate to severe flare-ups over a year, with the Comorbidity Index being particularly significant (with a Hazard Ratio of 1.58). This research is important because it helps identify patients who are at greater risk for complications, allowing for better management of their health. Who this helps: This helps patients with COPD and their doctors in managing their overall health.

PubMed

The Role of the Coagulation System in Peripheral Arterial Disease: Interactions with the Arterial Wall and Its Vascular Microenvironment and Implications for Rational Therapies.

2022

International journal of molecular sciences

Miceli G, Basso MG, Rizzo G, Pintus C, Tuttolomondo A

Plain English
This study looked at how blood clotting plays a role in worsening Peripheral Arterial Disease (PAD), a condition caused by the hardening of arteries that can lead to serious health issues. The findings highlight the importance of the coagulation system in different types of artery plaques, which can affect how we treat PAD. For instance, recognizing the connection between clotting and inflammation may help tailor treatments to better suit individual patients. Who this helps: Patients with Peripheral Arterial Disease.

PubMed

A case of infective colitis due to Yersinia enterocolitica complicated by microliver abscesses mimicking multiple liver occult metastases: a case report.

2021

BMC infectious diseases

Norrito RL, Pintus C, Cataldi M, Del Cuore A, Daidone M +8 more

Plain English
This study describes a rare case of a 79-year-old woman who developed intestinal infection caused by the bacteria Yersinia enterocolitica, leading to small liver abscesses that appeared similar to cancer spread. After noticing her symptoms and conducting various tests, doctors identified the infection and treated it successfully with antibiotics. This case highlights that such infections can mimic more serious conditions like cancer, reminding healthcare providers to consider bacteria as a possible cause of liver issues even in patients without typical risk factors. Who this helps: This helps doctors who diagnose and treat similar infections.

PubMed

International consensus conference on stool banking for faecal microbiota transplantation in clinical practice.

2019

Gut

Cammarota G, Ianiro G, Kelly CR, Mullish BH, Allegretti JR +24 more

Plain English
This study focused on how to improve access to faecal microbiota transplantation (FMT) for patients suffering from recurrent infections like C. difficile. Experts from various countries agreed on important guidelines for setting up stool banks, which would help ensure safe, reliable access to FMT by standardizing donor selection, stool processing, and ongoing monitoring. This is important because it could lead to more patients receiving effective treatment for infections that are hard to manage with standard medications. Who this helps: This helps patients who need FMT, particularly those with recurrent C. difficile infections.

PubMed

Stem cells to restore insulin production and cure diabetes.

2017

Nutrition, metabolism, and cardiovascular diseases : NMCD

Sordi V, Pellegrini S, Krampera M, Marchetti P, Pessina A +5 more

Plain English
This research paper looks at using stem cells to treat diabetes, focusing on how they could help restore insulin production and address complications of the disease. Currently, no stem cell therapies are officially approved for diabetes treatment, but several are being tested in clinical trials. The study highlights three main areas for potential use: rebuilding insulin-producing cells, modifying the immune response in type 1 diabetes, and tackling complications from the disease. Who this helps: This benefits patients with diabetes looking for new treatment options.

PubMed

European consensus conference on faecal microbiota transplantation in clinical practice.

2017

Gut

Cammarota G, Ianiro G, Tilg H, Rajilić-Stojanović M, Kump P +24 more

Plain English
This study brought together 28 experts from 10 countries to create guidelines for using faecal microbiota transplantation (FMT) in treating infections and other gut-related disorders. They found that FMT is a promising treatment but requires standardized procedures for safety and effectiveness. Their recommendations aim to help doctors implement FMT more widely and effectively, ensuring that the treatment is both safe and regulated. Who this helps: This helps patients suffering from infections and gut-related disorders.

PubMed

Complete Resolution of Retroperitoneal Lymphangioma with a Single Trial of OK-432 in an Infant.

2016

Pediatrics and neonatology

Olivieri C, Nanni L, De Gaetano AM, Manganaro L, Pintus C

Plain English
This study looked at a rare condition called retroperitoneal lymphangioma in an infant, which is a non-cancerous growth that can cause problems by pressing on nearby organs. The researchers treated the baby with a single injection of a drug called OK-432, and it completely resolved the lymphangioma without the need for surgery. This is significant because it shows a less invasive treatment option that can prevent complications associated with surgery. Who this helps: This helps infants with retroperitoneal lymphangioma and their families.

PubMed

Role of the EU Framework in Regulation of Stem Cell-Based Products.

2013

Advances in biochemical engineering/biotechnology

Migliaccio G, Pintus C

Plain English
This study looked at how stem cell treatments are controlled in Europe. It found that there are two main sets of rules governing stem cell use: one for transplants, which ensures safety and tracking, and another for medicines that regulates production and approval. Understanding these regulations is important to ensure patients receive safe and effective stem cell therapies. Who this helps: Patients receiving stem cell treatments.

PubMed

Extrinsic colonic obstruction by congenital fibrous band in an infant.

2013

BMJ case reports

Catania VD, Olivieri C, Nanni L, Pintus C

Plain English
This study looked at a premature baby who had a blockage in their intestine caused by a rare congenital fibrous band. The blockage was identified during surgery, and there were no clear signs to diagnose it before the operation. This matters because understanding such rare cases can help doctors recognize similar issues in other infants more quickly. Who this helps: This helps doctors and healthcare professionals caring for newborns with intestinal problems.

PubMed

Endoscopic retrieval of a duodenal perforating teaspoon.

2013

World journal of gastrointestinal endoscopy

Boškoski I, Tringali A, Landi R, Familiari P, Contini AC +2 more

Plain English
This study looked at a case where a 16-year-old girl with bulimia swallowed a 12 cm long teaspoon to induce vomiting, which led to a hole in her duodenum. The doctors successfully removed the teaspoon using a procedure called endoscopy and were able to close the hole without needing surgery. This indicates that endoscopy can be an effective method for removing large foreign objects and treating related injuries, potentially reducing the need for more invasive surgeries. Who this helps: This helps patients with eating disorders who may accidentally swallow large objects.

PubMed

Invasive fetal therapies: approach and results in treating fetal ovarian cysts.

2012

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Noia G, Riccardi M, Visconti D, Pellegrino M, Quattrocchi T +5 more

Plain English
This study looked at how treating fetal ovarian cysts before birth can prevent complications for both the mother and the baby. Researchers monitored 14 cases of these cysts and found that 92% of the pregnancies were successful, with 69% resulting in vaginal deliveries and no complications reported. By draining these cysts early, especially those larger than 40 mm, the team showed that it can prevent serious issues later on and support the health of the baby. Who this helps: This benefits expectant mothers and their babies facing the diagnosis of ovarian cysts during pregnancy.

PubMed

Acute pancreatitis associated with herpes simplex virus infection in a child.

2012

Pancreas

Olivieri C, Nanni L, Taddei A, Manzoni C, Pintus C

PubMed

Cribriform-morular variant of papillary thyroid carcinoma in an 8-year-old girl: a case report with immunohistochemical and molecular testing.

2012

International journal of surgical pathology

Rossi ED, Revelli L, Martini M, Taddei A, Pintus C +2 more

Plain English
This study focuses on a rare type of thyroid cancer called the cribriform-morular variant of papillary thyroid carcinoma in an 8-year-old girl. The researchers found that the cancer was spreading aggressively, with signs of invasion into surrounding tissues and lymph nodes, but no specific genetic mutations were detected. Understanding this unique case helps doctors better recognize and manage similar rare cancers in young patients. Who this helps: Patients with rare thyroid cancers and their families.

PubMed

Intradiaphragmatic hybrid lesion in an infant: case report.

2012

Journal of pediatric surgery

Olivieri C, Nanni L, Busato G, Rindi G, Marano R +1 more

Plain English
This study discussed a rare medical case involving an infant who had a mixed lung condition called a hybrid lesion, which has characteristics of both a congenital cyst and a blocked lung section. The doctors used a special imaging test called a CT scan to plan the surgery, but they confirmed the exact location for treatment only during the operation. Understanding these unique conditions helps healthcare providers offer better care to affected infants. Who this helps: This helps infants diagnosed with hybrid lung lesions and their families.

PubMed

Successful management of congenital chylous ascites with early octreotide and total parenteral nutrition in a newborn.

2012

BMJ case reports

Olivieri C, Nanni L, Masini L, Pintus C

Plain English
This study focused on a rare condition called congenital chylous ascites (CCA) in a newborn, where fluid builds up in the abdomen due to lymphatic issues. The researchers treated the baby with a combination of fasting, total parenteral nutrition (TPN), and octreotide for 15 days, successfully reducing the swelling. After treatment, the baby was able to breastfeed and went home healthy after 33 days without any return of the condition. Who this helps: This approach benefits newborns with congenital chylous ascites and their families.

PubMed

[Sacrococcygeal teratoma: single center experience and functional long-term follow-up].

2011

La Clinica terapeutica

Manzoni C, Canali R, Narciso A, Nanni L, Pintus C

Plain English
This study looked at the long-term health and quality of life of 28 patients who had sacrococcygeal teratoma (SCT), a type of tumor found at the base of the spine. Out of the group, 14 patients were followed for an average of about 10 years, revealing that 14% had issues with bowel control, 36% reported urinary problems, and only 21% were happy with their surgical scars. It highlights the importance of ongoing medical support and care for these patients, especially in terms of their physical function and emotional well-being. Who this helps: This helps patients with sacrococcygeal teratoma and their families, as well as healthcare providers involved in their care.

PubMed

Peculiar type 1 congenital pyloric atresia: a case report.

2010

Italian journal of pediatrics

Zecca E, Corsello M, Pintus C, Nanni L, Zecca S

Plain English
This study looked at a rare condition called pyloric atresia, which affects about 1 in 100,000 newborns. The researchers described a unique case where a premature baby had a special form of this condition that involved an unusual connection between the stomach and duodenum—a part of the small intestine—which required a special type of surgery. Prompt diagnosis of this condition is crucial to prevent serious health issues and ensure better results for affected infants. Who this helps: This helps newborns with pyloric atresia and their doctors.

PubMed

Solitary Peutz-Jeghers Polyp in a Paediatric Patient.

2010

Case reports in gastroenterology

Retrosi G, Nanni L, Vecchio FM, Manzoni C, Canali R +2 more

Plain English
This study looked at a rare type of polyp called a solitary Peutz-Jeghers polyp (PJP) in a child who did not have the symptoms typically associated with Peutz-Jeghers syndrome (PJS). The researchers found that while the child had a polyp causing a blockage in the intestine, they did not meet the criteria for PJS because they had no family history of the syndrome and did not show other typical signs. This finding suggests that solitary PJP may be a distinct condition separate from PJS, which is important for better diagnosing and treating patients with these types of polyps. Who this helps: This helps doctors and pediatric patients who may have similar polyps.

PubMed

Plexiform schwannoma of the esophagus in a child with neurofibromatosis type 2.

2009

Journal of pediatric surgery

Retrosi G, Nanni L, Ricci R, Manzoni C, Pintus C

Plain English
This study looks at a rare type of tumor called a plexiform schwannoma that appeared in the esophagus of an 11-year-old child with neurofibromatosis type 2, a genetic condition that can cause tumors to grow on nerves. The child successfully had the tumor surgically removed. This is significant because esophageal schwannomas are extremely uncommon, especially in children, with most cases reported in adults, which expands our understanding of how neurofibromatosis can affect young patients. Who this helps: This helps doctors and researchers understand and treat rare tumors in children with neurofibromatosis.

PubMed

[Percutaneous endoscopic gastrostomy (PEG) in pediatric patients: our experience and proposal of follow-up methodology].

2008

La Clinica terapeutica

Canali R, Sciascia Cannizzaro G, Scaldaferri A, Retrosi R, Contini AC +2 more

Plain English
This study looked at how effective and safe a feeding tube method called percutaneous endoscopic gastrostomy (PEG) is for kids, focusing on 33 children and 5 adults over several years. The researchers found that there were very few problems during the procedure, with complications occurring in just 3 cases, and only 1 child experienced worsening symptoms related to acid reflux after the PEG was placed. This matters because it shows that PEG can be a good option for long-term feeding in children, and proper follow-up care is essential to monitor any issues. Who this helps: This benefits pediatric patients who need long-term feeding support and their families.

PubMed

[Esophageal atresia. Personal experience and review of the literature].

2007

Annali italiani di chirurgia

Buonuomo V, Nanni L, Canali R, Pintus C

Plain English
This study looked at a rare condition called long gap esophageal atresia, where the two ends of the esophagus are far apart and need surgery to connect them. Researchers examined 16 children treated at their hospital between 2000 and 2006, finding that 5 (31%) of them had a long gap. In four cases, surgery to connect the esophagus was done at an average of 63 days old, and many children had success with a method called circular myotomy, which helps lengthen the esophagus. Who this helps: This benefits patients with long gap esophageal atresia and their families.

PubMed

Complete epididymal separation presenting as polyorchidism.

2006

Journal of clinical ultrasound : JCU

Zuppa AA, Nanni L, Di Gregorio F, Visintini F, Buonuomo V +1 more

Plain English
In this study, doctors examined a 21-month-old boy who had an unusual case where his testis and epididymis were completely separated. Initially, they thought he had an extra testis, but imaging tests showed something different, and surgery confirmed that only one testis was present, and it was surgically fixed in place. This is important because it highlights a rare condition that can be misdiagnosed, helping to ensure that children receive the right treatment. Who this helps: This helps doctors and their patients in understanding and treating uncommon testicular conditions.

PubMed

Fibromyxoid sarcoma in a 4-year-old boy: case report and review of the literature.

2005

Pediatric surgery international

Rando G, Buonuomo V, D'Urzo C, Vecchio F, Caldarelli M +1 more

Plain English
Researchers studied a rare type of tumor called low-grade fibromyxoid sarcoma in a 4-year-old boy. This case is unusual because the tumor grew near the spine, affecting the area between the second and first lumbar vertebrae, and it is one of the youngest known cases of this disease. Understanding such cases helps improve awareness and treatment options for similar tumors in children. Who this helps: This helps doctors and families of young patients with rare tumors.

PubMed

Evaluation of satisfaction level by parents and children following pediatric anesthesia.

2005

Paediatric anaesthesia

Iacobucci T, Federico B, Pintus C, de Francisci G

Plain English
This study looked at how satisfied parents and children are after kids receive anesthesia for surgery. Researchers surveyed 179 parents and found that most were very satisfied, especially when their children felt comfortable and received good care from the medical staff. Specifically, parents reported high satisfaction linked to the environmental comfort and positive interactions with the anesthetists and nurses, while children who were calm before the surgery experienced less anxiety. Who this helps: This helps parents and children going through pediatric surgeries by improving their care experience.

PubMed

Major anastomotic dehiscence after repair of esophageal atresia: conservative management or reoperation?

2005

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

D'Urzo C, Buonuomo V, Rando G, Pintus C

Plain English
This study looked at how to handle a serious complication (called anastomotic dehiscence) that can occur after surgery to fix a condition called esophageal atresia in newborns. Researchers found that instead of redoing the surgery after the complication, they could safely manage it with supportive care, and in one case, this approach led to successful healing after 43 days. This finding is important because it shows that in stable patients, conservative treatment can be effective even when there is a significant leakage after surgery. Who this helps: This approach benefits both newborn patients with esophageal atresia and their doctors by providing alternative treatment options.

PubMed

Cystic dysplasia of the rete testis associated to cryptorchidism: a case report.

2005

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica

Nanni L, Buonuomo V, Gessi M, Lauriola L, Pintus C

Plain English
This study examined a unique case of cystic dysplasia of the rete testis in a 10-year-old boy who had previously undergone surgery for undescended testes. After nine months, he developed a noticeable lump in his scrotum, and tests revealed a large cyst in the testis, which was confirmed through surgery as cystic dysplasia. The findings are important because they help doctors recognize this rare condition in children, allowing for better treatment options. Who this helps: This helps pediatric patients and their healthcare providers.

PubMed

[Utility and safety endoscopic digestive procedure in pediatric age].

2005

La Pediatria medica e chirurgica : Medical and surgical pediatrics

Fundarò C, Pantanella A, Genovese O, Rando G, Pintus C

Plain English
This study looked at the safety and usefulness of endoscopic procedures, like taking a closer look inside the digestive system, in children with serious stomach problems. Out of 87 procedures performed on children aged 3 months to 15 years, 92.5% confirmed a diagnosis of gastrointestinal diseases, such as coeliac disease and gastritis, with very few complications observed. This is important because it shows that these procedures can be safely used to diagnose stomach issues in kids, helping to identify serious conditions early. Who this helps: Patients, especially children with gastrointestinal symptoms.

PubMed

Congenital cystic adenomatoid malformation of the lung (CCAM) in children. Indications to early treatment in asymptomatic patients.

2004

The Journal of cardiovascular surgery

Briganti V, Pintus C, Manzoni C, Vallasciani S, Nanni L +1 more

PubMed

Malignant retroperitoneal paraganglioma: case report and review of the literature.

2004

Pediatric hematology and oncology

Buonuomo V, Ruggiero A, Rando G, D'Urzo C, Manzoni C +1 more

Plain English
This study looked at a rare tumor called retroperitoneal paraganglioma in an 11-year-old boy who was diagnosed by chance. The researchers found that the best treatment is often surgery to remove the tumor, which may be preceded by chemotherapy to shrink it. They also noted that a type of radiotherapy can help ease pain and make surgery possible in cases that seem hard to operate on. Who this helps: This helps doctors treating young patients with rare tumors.

PubMed

Laparoscopic approach to müllerian derivatives in a male with mixed gonadal dysgenesis.

2003

Surgical laparoscopy, endoscopy & percutaneous techniques

Nanni L, D'Urzo C, Pintus C, Riccipetitoni G, Perrelli L

Plain English
This study focused on a patient with mixed gonadal dysgenesis, a condition where the development of sexual organs is abnormal. The researchers successfully removed a large prostatic utricle using a minimally invasive laparoscopic technique, which is generally safer and leads to quicker recovery than traditional surgery. This matters because it shows a less risky option for treating patients with similar conditions, improving their health outcomes. Who this helps: This helps patients with mixed gonadal dysgenesis and similar conditions.

PubMed

Choledochal cyst in a pediatric patient: creation of a bilijejunal anastomosis with surgical staples. A case report.

2003

La Pediatria medica e chirurgica : Medical and surgical pediatrics

Vallasciani S, Pintus C, Grottesi A, Riccioni M

Plain English
This paper describes the successful surgery of a 12-year-old girl who had a type-IV choledochal cyst, a condition affecting the bile ducts. The doctors removed the cyst and connected the bile duct to the intestine using surgical staples, a method not often used for this type of surgery in children. This matters because it shows that surgical staples can be a safe and effective way to perform complex surgeries on children, potentially improving recovery times and outcomes. Who this helps: This helps pediatric patients with biliary issues and the surgeons treating them.

PubMed

Complications and conversions of pediatric videosurgery: the Italian multicentric experience on 1689 procedures.

2002

Surgical endoscopy

Esposito C, Mattioli G, Monguzzi GL, Montinaro L, Riccipetiotoni G +6 more

Plain English
This study looked at the safety of videosurgery for children by examining nearly 1,700 procedures conducted in eight hospitals in Italy over four years. The researchers found that 4.6% of these surgeries (79 cases) had complications, with 72% of those complications resolved using videosurgery and 28% needing to switch to open surgery. Importantly, there were no deaths, and all the children were healthy at follow-up, which highlights the effectiveness and safety of videosurgery when done correctly. Who this helps: This benefits pediatric patients and their families, ensuring safer surgical options.

PubMed

Sacrococcygeal teratoma. Outcome and management. An analysis of 17 cases.

2002

Journal of perinatal medicine

Perrelli L, D'Urzo C, Manzoni C, Pintus C, De Santis M +2 more

Plain English
This study looked at 17 cases of sacrococcygeal teratoma (SCT), a type of tumor found at the base of the spine in babies, to understand how it affects health and treatment outcomes. Out of the 17 cases, 14 babies had the tumors successfully removed, and 12 of them are now healthy and tumor-free. However, three babies died, including one with a dangerous tumor type, which highlights the importance of early detection and careful management of SCT. Who this helps: This information is useful for doctors, particularly those working with expectant parents and newborns affected by SCT.

PubMed

Bilateral renal vein thrombosis as a complication of gangrenous appendicitis.

2002

La Pediatria medica e chirurgica : Medical and surgical pediatrics

Nanni L, Vallasciani S, D'Urzo C, Rollo M, Chiaretti A +2 more

Plain English
This study looked at a rare case of a 10-year-old boy who developed blood clots in both of his renal veins after having surgery for a severely inflamed appendix. The researchers found that the best way to diagnose this condition quickly is by using a specific imaging test called color duplex Doppler, and they highlighted that peritoneal dialysis can effectively protect the kidneys from lasting harm. This matters because it shows a serious complication that can arise from a common surgery and emphasizes the importance of prompt diagnosis and treatment to safeguard kidney health. Who this helps: This helps doctors and pediatric patients facing similar surgical procedures.

PubMed

Varicocele in pediatric patients: comparative assessment of different therapeutic approaches.

2001

Urology

Pintus C, Rodriguez Matas MJ, Manzoni C, Nanni L, Perrelli L

Plain English
This study looked at different treatment methods for varicocele, a condition in boys that can affect testicular growth. Researchers examined 99 boys aged 9 to 16 and found that the original Palomo procedure had the lowest recurrence rate of varicocele at just 1.85%, compared to higher rates of 15% to 16.6% for other methods. This is important because it suggests a more effective way to treat this condition, helping to ensure better health outcomes for young patients. Who this helps: This helps pediatric patients with varicocele and their doctors in making treatment decisions.

PubMed

An original technique for bladder autoaugmentation with protective abdominal rectus muscle flaps: an experimental study in rats.

2001

The Journal of surgical research

Manzoni C, Grottesi A, D'Urzo C, Pintus C, Fadda G +1 more

Plain English
This study examined a new surgical technique to improve bladder capacity by using muscle flaps to protect the bladder lining in rats. The researchers tested this method on 30 rats, finding that those who received the new technique saw their bladder capacity increase by 38%, while the control group did not see this improvement. This approach appears to prevent complications that can occur with traditional methods, making bladder surgeries safer and more effective. Who this helps: This benefits patients needing bladder surgery, particularly those at risk for complications.

PubMed

Thyroid tumors in children and adolescents: preoperative study.

2001

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie

Ardito G, Pintus C, Revelli L, Grottesi A, Modugno R +3 more

Plain English
This study examined how to effectively diagnose thyroid tumors in children and teenagers before surgery. Out of 15 confirmed cases of cancer in the 50 patients studied, 11 were correctly identified as malignant before surgery using a specific test called fine-needle aspiration cytology (FNAC). This finding is important because early and accurate diagnosis can lead to better treatment outcomes for young patients with thyroid tumors. Who this helps: This helps patients and doctors involved in the care of children and adolescents with thyroid issues.

PubMed

Recurrent peptic stenosis of the esophagus: treatment with a self-expanding metallic stent.

2000

Surgical laparoscopy, endoscopy & percutaneous techniques

Pintus C, Valeri S, Riccioni M, Ciletti S, Coppola R +1 more

Plain English
This study focused on a 12-year-old boy with a narrow esophagus caused by repeated scarring from acid reflux. He was treated with a self-expanding metallic stent, which safely stayed in place for three months and successfully improved his condition. This finding is important because it shows that using this type of stent can effectively help patients with similar esophagus problems. Who this helps: This helps patients with esophageal narrowing due to acid reflux.

PubMed

Laparoscopic approach for nonpalpable abdominal testis.

1997

Surgical laparoscopy & endoscopy

Pintus C, Coppola R, Talamo M, Ciletti S, Riccioni ME +2 more

Plain English
This study looked at a surgical method for fixing abdominal testicles in young boys who couldn't feel the testicle through the skin. Researchers used a two-stage laparoscopic technique on five boys aged 2 to 10 years, and it worked well for all of them without complications. After a follow-up of 6 to 18 months, none of the boys experienced testicle shrinkage, which is a common concern with other methods. Who this helps: This helps young boys with undescended testicles and their parents.

PubMed

[Cryptorchidism: a study of histological changes in undescended testis related to age].

1997

La Pediatria medica e chirurgica : Medical and surgical pediatrics

Perrelli L, Pintus C, Manzoni C, Lauriola L, Capelli A

Plain English
This study looked at 46 testicular samples to understand the tissue changes in undescended testicles, commonly known as cryptorchidism, in boys aged 2 months to 14 years. Researchers found that the older the child, the more tissue damage was present in the undescended testicles, but how far the testicle had descended did not clearly affect the level of damage. These findings highlight the importance of addressing undescended testicles earlier to potentially prevent more serious tissue problems. Who this helps: This helps children with undescended testicles and their doctors.

PubMed

The rationale for total hip replacement in over 60-year-old patients.

1996

Archives of gerontology and geriatrics

Gusso MI, Piso L, Capone A, Ennas F, Pintus C

Plain English
This study looked at how total hip replacements (THR) work for patients over 60 years old, focusing on the different materials and techniques used. It found that choosing the right type of hip implant based on a patient’s bone quality, health conditions, and activity level is crucial for long-term success. For patients aged 60 to 70, understanding these factors helps ensure the implant fits well and lasts longer, ultimately reducing the risk of complications. Who this helps: This helps older patients needing hip replacements and their doctors make better decisions about the surgery.

PubMed

Laparoscopic cholecystectomy in a 23-month-old infant.

1995

Surgical laparoscopy & endoscopy

Pintus C, Coppola R, Talamo M, Perrelli L

Plain English
This study looked at a 23-month-old girl who underwent a less invasive surgery called laparoscopic cholecystectomy to remove her gallbladder. The researchers found that using this method is safer for young children and doesn't add extra risks compared to traditional surgery. This is important because it can lead to quicker recoveries and less pain for pediatric patients undergoing similar procedures. Who this helps: This helps young patients and their families by providing safer surgical options.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.