Chiara Lauritano

Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Via F. Acton 55, 80133 Napoli, Italy.

50 publications 2020 – 2026 ORCID

Publications in plain English

Special Issue "Microalgal Molecules and Enzymes 2.0".

2026

International journal of molecular sciences

Lauritano C, Saide A

Plain English
This study looked at the potential of microalgae to produce valuable substances like fats, sugars, and pigments that can be used in different industries. Researchers found that microalgae can effectively create these important molecules, which could be used in products ranging from food to cosmetics. This matters because using microalgae could lead to sustainable and more eco-friendly production methods. Who this helps: This benefits manufacturers and industries looking for sustainable raw materials.

PubMed

sp. Reduces Inflammation in LPS-Stimulated Human Malignant Melanoma and Immortalized Keratinocytes Influencing TNF-Release.

2026

Marine drugs

Montuori E, Hansen EH, McMullen CJ, Rietdorf K, Almeida C +3 more

Plain English
This study looked at a specific type of microalgae, referred to as sp. (BEA0050), to see if it could reduce inflammation in skin cancer cells. The researchers found that a substance derived from the algae, known as fraction D, significantly lowered inflammation and reduced a key inflammatory marker called TNF when tested on melanoma cells and skin cells affected by inflammation. Specifically, treating melanoma cells with 12.5 micrograms per milliliter of fraction D led to reduced activity in inflammatory pathways. Who this helps: This benefits patients with skin cancer and doctors looking for new treatment options.

PubMed

The Chemical Defensome: A Survey of Environmental Sensing and Response Genes in Copepods.

2025

International journal of molecular sciences

Roncalli V, Ascione D, Lauritano C, Carotenuto Y

Plain English
This study looked at how tiny ocean creatures called copepods respond to chemical stress in their environments by examining specific genes related to chemical defense. Researchers found that while the same set of protective genes is present across different types of copepods, the way these genes are expressed varies depending on the environment, indicating that copepods adapt to the specific challenges of their surroundings. Understanding this helps us monitor the health of marine ecosystems, which is crucial for predicting how changes in the environment may affect marine life. Who this helps: This information benefits marine biologists and environmental scientists who study ocean health.

PubMed

Chemical Defenses in Medusozoa.

2025

Marine drugs

Lincoln OJ, Houghton JDR, Zakariya M, Lauritano C, D'Ambra I

Plain English
This study looked at the different ways jellyfish and related creatures defend themselves, beyond just using toxins. Researchers found that these animals have various methods for protection, such as compounds that block UV light, antioxidants, and antimicrobial peptides. They noted that there is a lot of information on antimicrobial properties, which could be useful for developing new medicines, since many of these creatures are found in large groups and could be studied for their potential benefits. Who this helps: This helps researchers and medical professionals looking for new treatments and protective agents.

PubMed

Anthozoan Chemical Defenses: Integrating Compounds, Enzymatic Activities, and Omics-Based Discoveries.

2025

International journal of molecular sciences

Zakariya M, Lincoln OJ, D'Ambra I, Lauritano C

Plain English
This research focuses on a group of sea creatures called anthozoans, which have unique immune systems and produce various compounds that can help protect them from threats. The study found that these organisms have a variety of compounds with potential health benefits, such as fighting viruses, bacteria, and cancer. Understanding these natural defenses could lead to new medical treatments, but more research is needed to explore their full potential. Who this helps: Patients and healthcare providers looking for new treatment options.

PubMed

Greener Extraction Solutions for Microalgal Compounds.

2025

Marine drugs

Kopp G, Lauritano C

Plain English
This research paper looked at new, environmentally friendly ways to extract valuable compounds from microalgae, moving away from traditional methods that use harmful solvents. The review found that these green extraction methods can produce similar or even better yields of lipids and pigments compared to older techniques. This is important because it highlights a safer, more sustainable option for obtaining bioactive compounds that can be used in various applications. Who this helps: This benefits researchers and companies looking for safer extraction methods that are better for the environment.

PubMed

Lutein Production and Extraction from Microalgae: Recent Insights and Bioactive Potential.

2024

International journal of molecular sciences

Montuori E, Lima S, Marchese A, Scargiali F, Lauritano C

Plain English
This study looked at microalgae as a source of lutein, a pigment that is good for eye health and has other health benefits. Researchers found that microalgae can be effectively cultivated and engineered to produce more lutein, which can protect against cancer, inflammation, and heart disease. Given the aging population and the rising demand for lutein, finding efficient and sustainable ways to produce it is essential. Who this helps: This helps patients, especially older adults, who may benefit from lutein's health effects.

PubMed

Autonomic and hedonic response to affective touch in autism spectrum disorder.

2024

Autism research : official journal of the International Society for Autism Research

Capiotto F, Romano Cappi G, Mirlisenna I, Mazza A, Cicinelli G +3 more

Plain English
This study looked at how adults with Autism Spectrum Disorder (ASD) respond to affectionate touch compared to those without autism. Researchers found that while people with ASD reported stronger feelings—both positive and negative—about touch, their bodies did not react in the same way as those without autism; specifically, their skin didn't show the same increase in response when touch was meant to feel good. Understanding this gap is important because it sheds light on the unique challenges faced by individuals with ASD, which can help improve diagnosis and treatment options. Who this helps: This helps patients with autism and their healthcare providers.

PubMed

Marine Microalgal Products with Activities against Age-Related Cardiovascular Diseases.

2024

Marine drugs

Yurika N, Montuori E, Lauritano C

Plain English
This research focused on how products made from marine microalgae might help prevent heart diseases that often come with aging. The studies reviewed found particularly promising benefits from components of microalgae, such as polysaccharides, peptides, and carotenoids, suggesting they could play a role in reducing risks related to heart disease. This is important because heart disease kills about 17.9 million people every year, and finding effective prevention methods could save many lives. Who this helps: Patients at risk of heart disease, particularly the elderly.

PubMed

Comparative Transcriptomics to Identify RNA Writers and Erasers in Microalgae.

2024

International journal of molecular sciences

Ambrosino L, Riccardi A, Welling MS, Lauritano C

Plain English
This study looked at how certain enzymes that add or remove chemical markers on RNA behave in four types of microalgae when they face stressful conditions, like nutrient shortages. It discovered that almost all expected enzymes were present in the algae, with three specific enzymes missing likely due to them not being active under the conditions tested. Understanding these enzymes is important because they help regulate how microalgae respond to stress, which could affect their growth and survival in changing environments. Who this helps: This research helps scientists studying algae and their responses to environmental stressors.

PubMed

Salinity Stress Acclimation Strategies insp. Revealed by Physiological, Morphological and Transcriptomic Approaches.

2024

Marine drugs

Lauritano C, Bazzani E, Montuori E, Bolinesi F, Mangoni O +3 more

Plain English
This study looked at how a specific marine organism responds to different levels of salt in the water. Researchers found that it can grow well even in very salty conditions (up to 70 parts per thousand) and maintains good photosynthesis, but when the salinity is at its highest, it loses important structures called flagella. Understanding these adaptation strategies is important for marine biology and could help in developing better biotechnologies that use these organisms. Who this helps: This helps researchers and biotechnologists working with marine species.

PubMed

Physiology and functional biology of Rhizostomeae jellyfish.

2024

Advances in marine biology

Nagata RM, D'Ambra I, Lauritano C, von Montfort GM, Djeghri N +4 more

Plain English
This research looked at Rhizostomeae jellyfish, which are notable for their large size and unique shape, and how they function in their environment. The study found that these jellyfish have more than double the carbon content compared to other jellyfish, swim twice as fast, and consume more oxygen. This information is important because it helps scientists understand how these jellyfish interact with their ecosystems and affects human activities, such as fishing and tourism. Who this helps: This helps ecologists and environmental planners.

PubMed

Rhizostomes as a resource: The expanding exploitation of jellyfish by humans.

2024

Advances in marine biology

Brotz L, Angel DL, D'Ambra I, Enrique-Navarro A, Lauritano C +2 more

Plain English
This study focused on how jellyfish, particularly a group called Rhizostomeae, are being increasingly used by humans in various ways beyond just food. Researchers found that hundreds of thousands of tonnes of jellyfish are caught each year, with their benefits extending into areas like medicine, cosmetics, and agriculture, thanks to their rich collagen and potential for treating conditions like hypertension and cancer. This matters because it highlights a growing resource that could be valuable for health and environmental solutions, but we need to be careful about overfishing as interest in jellyfish grows. Who this helps: This helps patients, farmers, and the environment.

PubMed

Antiviral Activity of the Marine Haptophyta.

2024

Marine drugs

Montuori E, Ambrosino A, Della Sala G, Ragozzino C, Franci G +5 more

Plain English
This study looked at compounds derived from marine plants to see if they could fight viruses. Researchers found that a specific extract, known as fraction C, showed strong antiviral effects against the herpes virus, specifically HSV-1. This is important because, while many viral infections are still without effective treatments, discovering new antiviral options could help reduce illness and death from these infections. Who this helps: This research benefits patients suffering from viral infections, particularly those caused by the herpes virus.

PubMed

Marine Natural Products with Activities against Prostate Cancer: Recent Discoveries.

2023

International journal of molecular sciences

Montuori E, Hyde CAC, Crea F, Golding J, Lauritano C

Plain English
Researchers examined natural substances found in marine organisms to see if they could be used to treat prostate cancer, which is the most common cancer in men with over 52,000 new cases diagnosed each year. They found promising compounds that could potentially lead to new treatments and are currently being tested in clinical trials. This is important because current prostate cancer treatments can vary greatly in effectiveness and side effects, so new options could offer better outcomes for patients. Who this helps: Patients with prostate cancer.

PubMed

Transcriptome Sequencing of the Diatomand In Silico Identification of Enzymes Potentially Involved in the Synthesis of Bioactive Molecules.

2023

Marine drugs

Montuori E, Martinez KA, De Luca D, Ianora A, Lauritano C

Plain English
This study focused on two types of diatoms, a kind of microalgae known for their potential health benefits. Researchers sequenced their genetic material to identify specific enzymes linked to compounds that may fight cancer and support the immune system. They found several important enzymes that could be key to producing these beneficial compounds, with some showing increased activity under certain growing conditions. Who this helps: This information can help researchers and companies develop new treatments and products in health, nutrition, and cosmetics.

PubMed

In Silico Methodologies to Improve Antioxidants' Characterization from Marine Organisms.

2023

Antioxidants (Basel, Switzerland)

Lauritano C, Montuori E, De Falco G, Carrella S

Plain English
This study looks at how new computer-based methods can help identify and understand useful substances found in marine organisms, like antioxidants, which have many industrial applications. By using these in silico techniques, researchers can speed up the process of finding and testing these substances, potentially saving time and research costs. The review highlights that these methods are not yet widely utilized but could significantly enhance the discovery of bioactive molecules. Who this helps: This benefits researchers and companies looking to develop new health products from marine sources.

PubMed

Microalgae from Cold Environments and Their Possible Biotechnological Applications.

2023

Marine drugs

Montuori E, Saggiomo M, Lauritano C

Plain English
This paper studied microalgae that thrive in cold environments like deep oceans and polar regions. Researchers found that these microalgae have beneficial properties, such as fighting cancer and acting as antioxidants, and highlighted that they can be cultivated sustainably with minimal environmental impact. This is important because it opens up new ways to use these natural resources for human health without damaging their habitats. Who this helps: Patients and healthcare providers looking for sustainable treatment options.

PubMed

Microbial Interactions between Marine Microalgae and Fungi: From Chemical Ecology to Biotechnological Possible Applications.

2023

Marine drugs

Lauritano C, Galasso C

Plain English
This research paper examines how marine fungi and microalgae communicate chemically and how this interaction can lead to useful outcomes for humans. The review highlights the potential benefits of these chemical compounds in areas like improving human health, treating pollution, and enhancing water quality. Further research is needed since this area is less studied than the interactions between microalgae and bacteria, but the findings thus far show promise for significant advancements. Who this helps: This helps scientists, environmentalists, and health professionals looking for new ways to address ecological and health challenges.

PubMed

spp.: From Toxicity to Potential Biotechnological Benefits.

2023

Marine drugs

Montuori E, De Luca D, Penna A, Stalberga D, Lauritano C

Plain English
This research paper looked into certain types of tiny ocean plants called dinoflagellates that can produce toxins harmful to marine life and humans. The study found that some species of these dinoflagellates might also create substances that could be used to fight cancer, bacteria, viruses, and diseases like Alzheimer's. Understanding how to encourage the growth of these beneficial compounds could lead to new health treatments and improvements in fish farming. Who this helps: This benefits patients, healthcare providers, and the aquaculture industry.

PubMed

First identification and characterization of detoxifying plastic-degrading DBP hydrolases in the marine diatom Cylindrotheca closterium.

2022

The Science of the total environment

Vingiani GM, Leone S, De Luca D, Borra M, Dobson ADW +3 more

Plain English
This study focused on a marine diatom called Cylindrotheca closterium, which has the ability to break down a common water pollutant known as di-n-butyl phthalate (DBP). Researchers discovered two enzymes, named DBPH1 and DBPH2, that help the diatom degrade DBP, with their activity increasing when exposed to higher concentrations of DBP. Specifically, after exposure to 5 and 10 mg/l of DBP for 24 and 48 hours, both enzymes showed increased production, indicating that they play a role in cleaning up this harmful chemical from water sources. Who this helps: This benefits environmental scientists and bioremediation specialists looking for natural solutions to reduce harmful pollutants in aquatic ecosystems.

PubMed

From the Sea for the Sight: Marine Derived Products for Human Vision.

2022

Frontiers in aging neuroscience

Brillante S, Galasso C, Lauritano C, Carrella S

Plain English
This research paper looks at how natural products from the ocean might help improve vision and treat eye diseases. It found that these marine compounds, such as those from sponges and algae, showed promising benefits in protecting and repairing cells in the eye, with various positive effects like reducing inflammation and oxidative stress. This is important because it could lead to new treatments for serious eye conditions that affect many people. Who this helps: This helps patients suffering from eye diseases.

PubMed

De Novo Transcriptome of the FlagellateIdentifies Genes Involved in the Metabolism of Antiproliferative Metabolites.

2022

Biology

Riccio G, Martinez KA, Ianora A, Lauritano C

Plain English
This study looked at a type of ocean microorganism called a flagellate, focusing on how it produces useful compounds that might help fight cancer. Researchers identified specific genes that become active during different growth phases of the microorganism and found that certain fractions of its extracts, particularly those rich in nucleosides and triglycerides, can inhibit the growth of human cancer cells without harming normal cells. These findings could lead to new treatments in the fight against cancer by leveraging the natural compounds produced by these organisms. Who this helps: Patients fighting cancer.

PubMed

Transcriptome Mining to Identify Genes of Interest: From Local Databases to Phylogenetic Inference.

2022

Methods in molecular biology (Clifton, N.J.)

De Luca D, Lauritano C

Plain English
This study looked at how to better use the increasing amount of genetic data available from many organisms, focusing on a method that helps scientists find specific genes and understand their relationships. The researchers developed a clear process for analyzing this data, which can be applied to various kinds of organisms, including marine protists. This matters because it makes it easier for scientists to explore and identify important genetic information that could lead to new discoveries in biology. Who this helps: This helps researchers and scientists studying genetics and evolution.

PubMed

Traumatic Brain Injury and Gut Brain Axis: The Disruption of an Alliance.

2022

Reviews on recent clinical trials

Ferrara M, Bertozzi G, Zanza C, Longhitano Y, Piccolella F +5 more

Plain English
This study looked at how traumatic brain injuries (TBI) affect the interactions between the brain and the gut, an area known as the brain-gut axis. The researchers reviewed 91 studies and found that four main pathways—microbiota, inflammation, nervous system signals, and hormones—show how the brain and gut influence each other. Understanding these connections is crucial for improving treatment and prevention of complications from TBIs. Who this helps: This benefits patients recovering from traumatic brain injuries and doctors treating them.

PubMed

Jellyfish as an Alternative Source of Bioactive Antiproliferative Compounds.

2022

Marine drugs

Riccio G, Martinez KA, Martín J, Reyes F, D'Ambra I +1 more

Plain English
This study looked at jellyfish as a potential source of compounds that can slow down cancer cell growth. Researchers found that specific extracts from jellyfish significantly reduced the survival of cancer cells, with the most effective ones containing fatty acids and small peptides. This is important because it shows that jellyfish could lead to new treatments for cancer, offering a novel way to fight the disease. Who this helps: This benefits patients with cancer by providing new treatment options.

PubMed

Multiple Myeloma: Possible Cure from the Sea.

2022

Cancers

Capalbo A, Lauritano C

Plain English
This study looks at potential new treatments for multiple myeloma, a type of blood cancer that affects plasma cells. It highlights two existing marine-derived drugs, BLENREP and Aplidin, and discusses other promising natural products from the sea that are in various stages of testing. Researchers found specific compounds that could effectively target cancer cells, emphasizing the need to explore the wide range of substances produced by marine life. Who this helps: This helps patients with multiple myeloma and their doctors.

PubMed

Recent Discoveries on Marine Organism Immunomodulatory Activities.

2022

Marine drugs

Montuori E, de Pascale D, Lauritano C

Plain English
This research paper explores the potential of substances from marine organisms, like fish and algae, to help the immune system and treat conditions like cancer and inflammation. It highlights that various compounds from these organisms can modify immune responses, which could lead to new treatments; for example, some compounds have been shown to enhance or inhibit immune responses in laboratory studies. The findings are important because they provide a new avenue for developing effective drugs, especially as the ocean offers many unique biological resources. Who this helps: This helps patients with cancer and immune-related diseases.

PubMed

Marine Compounds for Melanoma Treatment and Prevention.

2022

International journal of molecular sciences

Montuori E, Capalbo A, Lauritano C

Plain English
This research paper examines natural compounds found in marine organisms to treat and prevent melanoma, a type of skin cancer that affects about 132,000 people each year worldwide. One promising compound mentioned is Marizomib, derived from a marine bacterium, which is currently being tested in advanced clinical trials. These marine compounds may offer new ways to fight melanoma and improve patient outcomes. Who this helps: Patients diagnosed with melanoma and their healthcare providers.

PubMed

Chemosensory-Related Genes in Marine Copepods.

2022

Marine drugs

Roncalli V, Uttieri M, Capua ID, Lauritano C, Carotenuto Y

Plain English
This study looked at the genes that help copepods, tiny marine animals, sense chemicals in their environment, which is crucial for finding food and mating. Researchers analyzed data from 18 different copepod species and found specific chemosensory genes that help these creatures recognize chemical signals, while noting that they do not have certain receptors found in insects. This research is important because it enhances our understanding of how copepods communicate with their environment and may help in studying marine ecosystems more effectively. Who this helps: This helps scientists studying marine biology and ecology.

PubMed

The MicroalgaInduces Apoptosis and DNA Damage in K562 Cell Line by Modulating NADPH Oxidase.

2022

Molecules (Basel, Switzerland)

Ciarcia R, Longobardi C, Ferrara G, Montagnaro S, Andretta E +5 more

Plain English
This study looked at how a marine microalga called Skeletonema marinoi affects leukemia cells. Researchers found that after 48 hours of treatment, the microalga reduced the number of living leukemia cells by 50% and increased cell death by promoting apoptosis. It also changed the levels of specific proteins and molecules related to cell death and survival, which is important for developing new treatments for leukemia. Who this helps: This helps patients with chronic myeloid leukemia and their doctors looking for new treatment options.

PubMed

Fish Waste: From Problem to Valuable Resource.

2021

Marine drugs

Coppola D, Lauritano C, Palma Esposito F, Riccio G, Rizzo C +1 more

Plain English
This research paper looks at the significant problem of fish waste, which accounts for about two-thirds of all fish caught and can create serious economic and environmental issues. It highlights how fish waste can be transformed into valuable products like collagen and enzymes, which have various practical uses. By finding ways to recycle this waste, we can improve sustainability and support economic growth. Who this helps: This benefits the fishing industry, businesses that use fish byproducts, and the environment.

PubMed

A Metataxonomic Approach Reveals Diversified Bacterial Communities in Antarctic Sponges.

2021

Marine drugs

Ruocco N, Esposito R, Bertolino M, Zazo G, Sonnessa M +9 more

Plain English
This study looked at the types of bacteria living in four different Antarctic sponges. Researchers found a variety of bacteria that belong to important groups, including Proteobacteria and Bacteroidetes, with the sponges having many species known to produce useful compounds. This matters because these bacteria could lead to new medicines or treatments, especially since there have been few studies on Antarctic sponge bacteria. Who this helps: Patients and researchers looking for new medical treatments.

PubMed

Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds.

2021

International journal of molecular sciences

Saide A, Martínez KA, Ianora A, Lauritano C

Plain English
This research reviews the health benefits of microalgae, which can produce a variety of compounds that may help prevent and treat diseases due to their antioxidant, anti-inflammatory, anticancer, and antimicrobial properties. The study found that while some of these compounds are already known to have positive effects, more research is needed to fully understand how they work and how they can be used in medicine. This is important because harnessing these microalgae could lead to new treatments and healthier products for people. Who this helps: Patients looking for new treatments and doctors seeking innovative therapies.

PubMed

Promising Activities of Marine Natural Products against Hematopoietic Malignancies.

2021

Biomedicines

Saide A, Damiano S, Ciarcia R, Lauritano C

Plain English
This review looks at how products derived from marine organisms might help treat blood cancers, which are difficult to cure with current therapies. The study found that there are five marine-based compounds already used for treating these cancers, and two more that are being tested in clinical trials. This is important because many blood cancers still lack effective treatments, and marine products could offer new options with fewer side effects. Who this helps: This helps patients with blood cancers and their doctors by providing new treatment alternatives.

PubMed

Bioactivity Screening of Antarctic Sponges Reveals Anticancer Activity and Potential Cell Death via Ferroptosis by Mycalols.

2021

Marine drugs

Riccio G, Nuzzo G, Zazo G, Coppola D, Senese G +9 more

Plain English
This study looked at four types of sponges from Antarctica to see if they could help fight cancer by killing cancer cells. Researchers found that extracts from these sponges, particularly those containing a compound called mycalols, effectively reduced the growth of liver cancer (HepG2), lung cancer (A549), and melanoma cells (A2058). Specifically, certain genes related to a form of cell death called ferroptosis were significantly affected, indicating how these compounds may work in attacking cancer cells. Who this helps: This benefits cancer patients and researchers looking for new treatment options.

PubMed

First Report of OvoA Gene in Marine Arthropods: A New Candidate Stress Biomarker in Copepods.

2021

Marine drugs

Roncalli V, Lauritano C, Carotenuto Y

Plain English
This study examined a gene called OvoA in marine arthropods, particularly focusing on copepods. Researchers found that the OvoA gene is present in these creatures and plays a key role in helping them manage oxidative stress, especially during the copepod's developmental stage, where they undergo significant changes and show higher gene activity when under stress from harmful diets. This discovery is important because it may allow scientists to use OvoA as a reliable indicator of stress in copepods and could open up new pathways for developing marine-based medications. Who this helps: This benefits marine biologists and researchers in drug development.

PubMed

A Treasure of Bioactive Compounds from the Deep Sea.

2021

Biomedicines

Saide A, Lauritano C, Ianora A

Plain English
This study looks at the unique organisms living in the deep sea, which face extreme conditions like darkness, high pressure, and low oxygen. Researchers found that these organisms can create special compounds that could be useful for treating human diseases, but very few of these compounds have been studied due to the challenges of reaching and sampling deep-sea environments. Understanding and utilizing these compounds could lead to new medicines, making it an important area of research. Who this helps: This helps patients looking for new treatments and doctors seeking innovative medical solutions.

PubMed

Editorial of Special Issue "Microalgal Molecules and Enzymes".

2021

International journal of molecular sciences

Lauritano C, Saide A

Plain English
This paper focuses on microalgae, which are tiny plants that use sunlight to grow and can thrive in many different places, even extreme ones like very hot or cold areas. The research highlights that these organisms can produce valuable substances and enzymes that could be useful in medicine and industry. Understanding microalgae better could lead to new treatments or products that benefit health and sustainability. Who this helps: This helps researchers and industries looking for new natural resources and solutions.

PubMed

Potential ApproachesApproved or Developing Chronic Myeloid Leukemia Therapy.

2021

Frontiers in oncology

Andretta E, Costa C, Longobardi C, Damiano S, Giordano A +5 more

Plain English
This research paper looked at new treatment options for chronic myeloid leukemia (CML), especially for patients who have become resistant to the current medications called tyrosine kinase inhibitors (TKIs). It found that new therapies are being tested, including drugs that target specific cancer cells and innovative treatments like antioxidants and natural products from marine life. These developments are important because they offer hope for better ways to treat CML and prevent patients from relapsing or worsening their disease. Who this helps: This helps patients with chronic myeloid leukemia.

PubMed

Curcumin Supplementation Protects Broiler Chickens Against the Renal Oxidative Stress Induced by the Dietary Exposure to Low Levels of Aflatoxin B1.

2021

Frontiers in veterinary science

Damiano S, Jarriyawattanachaikul W, Girolami F, Longobardi C, Nebbia C +7 more

Plain English
This study looked at how curcumin, a natural compound found in turmeric, can protect chickens from kidney damage caused by a toxin called aflatoxin B1 (AFB1). Researchers found that when chickens were fed AFB1, their kidney health worsened, shown by changes in important stress-related markers; for example, antioxidant levels decreased while harmful substances increased. However, when curcumin was added to their diet, it reversed these negative effects, suggesting it could help manage the damage caused by this toxin. Who this helps: This benefits farmers and poultry producers by potentially improving chicken health and reducing economic losses from aflatoxin contamination.

PubMed

Effects of a Red Orange and Lemon Extract in Obese Diabetic Zucker Rats: Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidase.

2020

Journal of clinical medicine

Damiano S, Lauritano C, Longobardi C, Andretta E, Elagoz AM +4 more

Plain English
This study looked at the effects of a red orange and lemon extract on diabetic kidney damage in obese diabetic rats. After 24 weeks, the rats that received the extract showed less kidney damage and improved markers of oxidative stress compared to those that did not get the treatment. Specifically, the extract reduced harmful enzymes and restored a healthy balance of proteins involved in cell death, which could help protect kidneys from diabetes-related harm. Who this helps: This benefits patients with diabetes, especially those at risk for kidney disease.

PubMed

Ten-Year Research Update Review: Antiviral Activities from Marine Organisms.

2020

Biomolecules

Riccio G, Ruocco N, Mutalipassi M, Costantini M, Zupo V +3 more

Plain English
This research paper looks at the antiviral properties of substances found in marine organisms, highlighting discoveries from the past decade. It shows that while many compounds from the ocean can fight viruses, only one, Ara-A, is currently available for use, and another, Griffithsin, is undergoing early testing. This is important because it emphasizes the potential for new antiviral medications derived from marine life, especially in light of the recent COVID-19 pandemic. Who this helps: This helps patients seeking new antiviral treatments, especially during health crises.

PubMed

De novo Transcriptome of the Non-saxitoxin ProducingReveals New Insights on Harmful Dinoflagellates.

2020

Marine drugs

Vingiani GM, Štālberga D, De Luca P, Ianora A, De Luca D +1 more

Plain English
This research studied a type of microscopic algae called dinoflagellates, which can produce harmful toxins affecting health and the environment. The scientists found that, although this particular dinoflagellate does not produce saxitoxins, it has genes that suggest it might produce other toxic compounds. Specifically, they identified three genes linked to saxitoxin production and 44 other genes that could be involved in making different toxins. Who this helps: This information benefits researchers and public health officials trying to understand and manage harmful algae blooms.

PubMed

De Novo Transcriptome Assembly and Gene Expression Profiling of the CopepodFeeding on the PUA-Producing Diatom.

2020

Marine drugs

Asai S, Sanges R, Lauritano C, Lindeque PK, Esposito F +2 more

Plain English
This study explored how certain diatoms, which are a type of algae, produce chemicals that negatively affect their main predators, called copepods. Researchers found that copepod females exposed to these diatom-produced chemicals had noticeable changes in gene expression related to stress response and embryo development, with 27 specific genes showing altered activity when faced with higher concentrations of these chemicals. Understanding how these chemicals impact copepod reproduction is important because it can help identify early warning signs of reproductive issues in marine ecosystems. Who this helps: This helps researchers studying marine life and conservation efforts aimed at preserving healthy ocean ecosystems.

PubMed

RNA-Seq and differential gene expression analysis in Temora stylifera copepod females with contrasting non-feeding nauplii survival rates: an environmental transcriptomics study.

2020

BMC genomics

Russo E, Lauritano C, d'Ippolito G, Fontana A, Sarno D +3 more

Plain English
This study looked at a type of tiny ocean creature called a copepod, specifically female Temora stylifera, to understand how their genes affect how well their young survive in different conditions. Researchers found that the survival rate of the baby copepods was only 25% on one date but soared to 93% a week later. They identified over 331 gene sequences that changed between the two sampling times, with many related to how the copepods respond to environmental stress, suggesting that certain chemicals from algae may hurt the baby copepods' survival. Who this helps: This research benefits marine biologists studying ocean ecosystems and environmental changes.

PubMed

A Review of Toxins from Cnidaria.

2020

Marine drugs

D'Ambra I, Lauritano C

Plain English
This research paper reviews the toxins found in jellyfish and other related organisms known as Cnidaria, which can cause painful stings and even be deadly to humans. The paper highlights that while many toxins have been studied, especially from certain types of jellyfish, significant progress has been made recently using new scientific techniques to better understand these venoms. This knowledge is important because it helps improve our understanding of how to treat stings and potentially develop antidotes or other medical applications. Who this helps: This helps patients who experience jellyfish stings and healthcare providers treating those stings.

PubMed

Chemical Defense in Marine Organisms.

2020

Marine drugs

Lauritano C, Ianora A

Plain English
This study looked at how marine animals protect themselves from harmful chemicals in their environment. Researchers found that certain species, like sea cucumbers and sponges, have developed specific chemical defenses to survive in polluted waters, which can be crucial for their health and safety. Understanding these defenses helps us learn more about how marine life adapts to changing conditions and can inform efforts to protect ocean ecosystems. Who this helps: This helps marine biologists and environmental scientists.

PubMed

First De Novo Transcriptome of the Copepodfrom Antarctic Waters.

2020

Biology

Lauritano C, Roncalli V, Ambrosino L, Cieslak MC, Ianora A

Plain English
This study examined the genetic material of a common tiny crustacean called copepod found in Antarctic waters. Researchers created a detailed genetic map, or transcriptome, for these creatures and found that they have genes that help them survive in freezing temperatures, including three genes linked to antifreeze proteins. This resource is important because it helps scientists understand how marine life adapts to extreme environments. Who this helps: This benefits researchers studying climate change and polar ecosystems.

PubMed

Physiological and Molecular Responses to Main Environmental Stressors of Microalgae and Bacteria in Polar Marine Environments.

2020

Microorganisms

Lauritano C, Rizzo C, Lo Giudice A, Saggiomo M

Plain English
This study looked at how tiny organisms like microalgae and bacteria in polar regions respond to extreme environmental changes, such as low temperatures and varying levels of light and salt. Researchers found that these conditions can change the types of species present, their growth rates, and trigger the production of protective compounds, which help them survive harsh climates. Understanding these responses is important because it helps us learn about how life can adapt to extreme environments and highlights the need for more research on these organisms. Who this helps: This helps scientists studying climate change and marine ecology.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.