Chien-Yu Pan

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This study examined how common convergence insufficiency (CI) is among elementary school students in Kaohsiung, Taiwan. The researchers found that about 35% of the 219 students assessed had at least one sign of CI, with 18% showing mild CI, 14% showing moderate CI, and 3% showing severe CI. These findings are important because they highlight the need for eye screenings in schools to catch and treat this vision problem early, particularly since girls were more likely to show mild signs while boys showed more serious issues. Who this helps: This helps students and their parents by identifying potential vision problems early.

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This study looked at a new type of surgery called single-port transoral robotic surgery (SP TORS) for treating various issues in the head and neck, including cancers and sleep apnea, in a hospital in Taiwan. Out of 12 patients who underwent this surgery, all had successful operations with minimal bleeding, and half did not need a feeding tube afterward. This matters because it shows that this robotic surgery can be done safely and effectively, offering a good option for patients with different head and neck conditions while promoting quicker recovery. Who this helps: This helps patients needing treatment for head and neck issues, including those with sleep apnea and tumors.

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This study focused on creating a new type of catalyst made from cobalt nanoparticles to improve the performance of aluminum-air batteries, which are energy sources that could replace expensive platinum-based catalysts. The researchers found that their cobalt-based catalyst had a peak power output of 191 milliwatts per square centimeter, surpassing the platinum catalyst's output of 132 milliwatts per square centimeter. This improvement is important because it could lead to more efficient and cheaper batteries for energy storage and conversion. Who this helps: This benefits battery manufacturers and consumers looking for more affordable and efficient energy solutions.

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This study looked at how to use machine learning to quickly identify urinary tract infections (UTIs) caused by a specific bacteria, rather than waiting for time-consuming lab culture results. Researchers examined data from 308 hospitalized patients and found that this bacteria was responsible for 51.3% of UTIs. They developed a machine learning model that can help predict UTIs with moderate accuracy, which could help doctors make faster treatment decisions. Who this helps: This helps patients and doctors by allowing quicker UTI diagnosis and treatment.

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This study looked at whether inline skating could help improve physical and thinking skills in Taiwanese children with ADHD. After 12 weeks of skating lessons, the children who participated showed better movement skills and cardiovascular fitness, with significant improvements in certain thinking abilities that lasted at least three months. This research is important because it shows a fun activity like skating can have lasting benefits for children with ADHD. Who this helps: This helps children with ADHD and their families.

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This study examined how a substance called Tilapia piscidin 4 (TP4), found in fish, affects bladder cancer cells. Researchers discovered that TP4 not only stopped these cancer cells from growing but also triggered their death through specific biological mechanisms. In laboratory tests, TP4 caused a 70% reduction in cell growth rates and led to significant increases in cell death markers. This research is important because it shows that TP4 might be a new treatment option for bladder cancer, potentially offering a safer way to combat this disease. Who this helps: This helps patients with bladder cancer looking for new treatment options.

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This study examined the effects of long-term Tai Chi and aerobic exercise on antioxidant levels and cognitive function in people with Parkinson's disease. After 12 weeks, those in the aerobic exercise group showed improved antioxidant levels and better cognitive function, while the Tai Chi group only had increased antioxidant levels. Overall, aerobic exercise was found to be more effective than Tai Chi in reducing oxidative damage and supporting brain health. Who this helps: This benefits patients with Parkinson’s disease, especially those in the early stages.

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This study looked at how a 6-week badminton class affects health and well-being in college students who had never played sports before. Twenty-two students, ages 18-23, participated in either badminton or soccer, meeting twice a week. Both groups got better in physical tests, but those playing badminton showed more improvement in agility. This is important because it highlights how university sports classes can improve both physical fitness and mental resilience, making activities like badminton a valuable option for beginners. Who this helps: This helps college students looking to improve their health and fitness.

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This study looked at the risks associated with using specific needles (20-22G) for a procedure called endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) on solid lesions in the upper digestive tract. Out of almost 10,000 patients, only 1.8% experienced complications, with bleeding occurring in 44% of those cases. This research is important because it shows that while complications can happen, they are generally mild and serious issues are rare, making this procedure relatively safe for patients. Who this helps: This benefits patients undergoing biopsies for digestive tract issues.

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This study looked at how adjusting a plant hormone called gibberellin (GA) can help rice plants grow better in challenging environments, like alkaline soil and high temperatures. Researchers found that using the right amounts of GA not only protects the plants from damage but also can increase yields, improving growth in tough conditions. Specifically, they identified a gene called ATT2 that helps control GA levels, which could be key for farming in less-than-ideal land situations. Who this helps: This benefits farmers growing rice, especially in areas with difficult soil and climate conditions.

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This study focused on improving solid-state lithium-sulfur batteries, which are safer alternatives to traditional lithium batteries but currently underperform. Researchers tested two types of solid electrolytes and found that lower quality electrolytes caused uneven charge flow and more lithium build-up (dendrites), cutting battery lifespan significantly. Specifically, they noted that poor solid electrolyte quality led to more dendrite formation, which threatens battery reliability and performance. Who this helps: This benefits battery manufacturers and consumers looking for safer, longer-lasting batteries.

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This study looked at how a short educational video could help breast cancer patients better understand radiation therapy and care for their skin during treatment. The video, which was just 4 minutes long and accessible via a QR code, was well-received: 90% of the 51 patients who completed the study found it satisfying and helpful for reducing anxiety. Most patients noticed more skin discomfort as treatment progressed, highlighting the need for continuous support and education. Who this helps: This benefits breast cancer patients undergoing radiation therapy, helping them manage side effects and feel more supported.

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This study analyzed various injection treatments for hand osteoarthritis to see how effective they are in reducing pain and improving hand function. Researchers looked at 14 clinical trials involving 674 patients and found that injections of platelet-rich plasma and dextrose significantly reduced pain scores and improved hand function over a long period (at least six months). Specifically, platelet-rich plasma had a mean pain reduction of 4.03 points, and dextrose reduced pain by 1.06 points, both leading to better hand function. Who this helps: This helps patients suffering from hand osteoarthritis.

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This study looked at two separate norovirus outbreaks in Southern California linked to eating raw oysters from different regions in Mexico. Around 400 people reported gastrointestinal illnesses, and 179 of those cases were specifically connected to the outbreaks, with 24 confirmed as norovirus infections. The research highlights the importance of safely handling and cooking oysters to prevent foodborne illnesses. Who this helps: This helps consumers and food safety regulators.

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This study looked at how the brain chemical glutamate increases zinc levels in nerve cells, which is important for their function. The researchers found that glutamate boosts zinc by activating specific receptors in the cells. They discovered that blocking certain proteins in this process prevented the increase in zinc, highlighting the link between glutamate, zinc, and inflammation in nerve cells. This is important because understanding how these processes work can help us develop better treatments for neurodegenerative diseases. Who this helps: This benefits patients with neurodegenerative disorders and their doctors.

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Researchers created a special material using cobalt in a new way to improve the performance of zinc-air batteries. They found that this material performed better than traditional platinum-based catalysts, achieving a significant increase in efficiency, which is important for making batteries more effective. This advancement is particularly relevant, as it could lead to cheaper and more efficient energy storage solutions. Who this helps: This helps battery manufacturers and consumers looking for better energy storage options.

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This study looked at how oxocrebanine, a compound from the plant Stephania hainanensis, affects the growth of liver cancer cells (specifically HepG2 and Hep3B2.1-7). Researchers found that oxocrebanine reduces cell growth in a dose-dependent manner and increases the rate of cell death by apoptosis. Additionally, it appears to trigger a protective process called autophagy that also contributes to reducing the cancer cell population. Who this helps: This research benefits patients with liver cancer by exploring potential new treatments.

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This study looked at the Free Fatty Acid Receptor 2 (FFA2), a part of the body that responds to short-chain fatty acids. Researchers found that FFA2 is important for managing inflammation, fat processing, insulin release, and appetite control, and they explored how certain synthetic drugs can activate this receptor in targeted ways. Understanding FFA2 better could lead to new treatments for conditions like obesity and neurodegenerative diseases. Who this helps: This helps patients with metabolic disorders and doctors seeking new treatment options.

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This study examined the effects of oxocrebanine, a compound from a traditional Chinese medicinal plant, on liver cancer cells. The researchers found that oxocrebanine significantly slowed the growth of these cancer cells by promoting cell death (apoptosis) and self-digestion (autophagy). Specifically, it decreased the growth of the cancer cells by promoting apoptosis and increasing the levels of certain proteins related to these processes. Who this helps: This benefits patients with hepatocellular carcinoma, a common type of liver cancer.

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This study looked at a new type of bone scaffold designed to help heal large bone defects by balancing strength and nutrient flow. The researchers found that the best scaffold model, which had 70% porosity, allowed for efficient fluid transport and supported the growth of bone cells significantly better than traditional designs. Specifically, this scaffold improved nutrient delivery and cell adhesion, making it a strong option for future use in surgeries to repair major bone damage. Who this helps: This benefits patients needing bone repair and the doctors performing their surgeries.

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This study looked at how a 12-week inline skating program affects children aged 6-12 with attention-deficit/hyperactivity disorder (ADHD). The results showed that after the skating sessions, these children had better ADHD symptoms, improved executive functions, and enhanced motor skills. Specifically, improvements were statistically significant, meaning the program worked well, and the benefits lasted for at least 12 weeks after the program ended. Who this helps: This helps children with ADHD by providing an effective exercise option to improve their symptoms and skills.

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This study looked at using a minimally invasive technique called transoral robotic surgery (TORS) for patients with oral tongue cancer who have difficulty opening their mouths, a condition known as trismus. The researchers evaluated 67 patients and found that 98.5% had clean surgical margins, meaning the cancer was fully removed, with a low complication rate and most patients able to eat again within two weeks. This is significant because it shows that TORS is safe and effective even in complicated cases, offering a better option than traditional surgery. Who this helps: This benefits patients with oral tongue cancer, especially those with trismus.

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This study explored a new material called (AEPPz)SbClO, which is a hybrid of organic and inorganic components, for use in detecting X-rays. The researchers found that this material has a high ability to emit light, with a photoluminescence quantum yield of 80.26%, and can produce clear X-ray images with a low detection threshold of 41 nGy per second. This development is important because it could lead to better and safer imaging techniques in medical diagnostics. Who this helps: Patients undergoing X-ray imaging and doctors who interpret those images.

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This study looks at how the balance of bacteria in the nose, known as nasal microbiota, affects allergic rhinitis (AR), a common condition causing sneezing and a runny nose. Researchers found that changes in the types and amounts of these bacteria are linked to the severity of AR symptoms, particularly through their connection to immune markers like immunoglobulin E. Understanding and potentially adjusting the nasal microbiota could lead to new treatments that address the root causes of AR rather than just the symptoms, which is important since AR affects many people's quality of life. Who this helps: Patients suffering from allergic rhinitis.

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This study investigated how the chemotherapy drug doxorubicin affects the effectiveness of another drug, carfilzomib, in treating multiple myeloma, a type of blood cancer. The researchers found that doxorubicin improved carfilzomib's ability to kill cancer cells by disrupting the formation of cellular structures called aggresomes, which protect cells from stress. Specifically, it enhanced cell death in the U266B1 cell line, while other cell lines showed less benefit, indicating that targeting aggresome formation may be a key strategy in treatment. Who this helps: Patients with multiple myeloma, especially those whose cancer cells form aggresomes.

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This study looked at brain activity, specifically through EEG (a way to measure electrical activity in the brain), while people completed a challenging task that required them to imagine a situation from another person's point of view. Researchers used a new method called Graph Neural Networks (GNNs) to better understand the connections between different parts of the brain, resulting in improved interpretation of the data. They found that focusing on long-range connections in the brain is crucial for understanding decision-making during difficult tasks, particularly emphasizing the importance of connections in the fronto-parietal network. Who this helps: This benefits researchers and clinicians studying brain function and cognitive processing.

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This study looked at how kinesiology taping (KT) affects balance and performance in college athletes with unstable ankles. The researchers found that taping at 35% tension improved proprioception (the body's ability to sense its position) and performance on balance tests, while taping at 0% tension worsened these factors. Specifically, athletes using 35% KT showed better balance with closed eyes and scored more successful hops, while performance decreased with lighter taping. Who this helps: This benefits athletes with chronic ankle instability by improving their stability and performance.

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This study looked at how accurately intraoral scanners can capture images of teeth in patients with varying levels of crowding. Researchers found that when teeth are severely crowded, the scanner's accuracy decreases, with the worst results in the upper jaw (maxillary arch). Specifically, the most crowded models had the highest deviations in measurements, but overall, the scanning accuracy was still considered acceptable. Who this helps: This information is beneficial for orthodontists who use intraoral scanners to plan treatments for patients with crowded teeth.

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This study focused on improving the growth and survival of purple sea urchin larvae in captivity to help with large-scale farming. Researchers found that mixing specific amounts of different kinds of microalgae and probiotics can significantly increase survival rates; for example, using 20,000 cells per mL of one type of algae and 5,000 cells per mL of a particular probiotic resulted in the best growth and survival outcomes. This matters because better-reared sea urchins can help meet the demand for seafood in the market. Who this helps: This benefits seafood producers and aquaculture farmers looking to optimize their production of sea urchins.

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This study focused on creating new materials that can effectively separate different types of water (HO and DO). The researchers found that these materials strongly attract HO, making them better at concentrating HO from mixtures compared to DO; this means they can improve the separation process. This is important because it could lead to better methods in water purification and related industries. Who this helps: This benefits researchers and engineers working on water treatment solutions.

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This study looked at new materials (borates) that can be used in zinc-air batteries, which are a type of battery designed to store and release energy. Researchers found that two specific compounds produced strong performance in helping these batteries work more effectively, with a key measurement (ORR performance) of 0.84 volts. This is important because it could lead to better and more efficient batteries for various uses. Who this helps: This benefits battery manufacturers and consumers looking for improved energy storage solutions.

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This study looked at the link between motor skills and thinking skills in children aged 6 to 12, comparing 48 children with autism to 48 typically developing children. The autistic children scored lower in motor skills and thinking tasks; for instance, they had significantly lower scores on tests measuring coordination and cognitive flexibility. These findings highlight the need for programs that can help improve both motor and thinking skills in autistic children. Who this helps: This research benefits children with autism and their caregivers by highlighting areas for targeted intervention.

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In this study, researchers developed a new type of lead-free material called In-based hybrid perovskites, which have special light-emitting properties. They found that by using different organic components and adding a substance called Sb, the materials produced bright light at various wavelengths, with photoluminescent efficiency values reaching up to 57.12%. This is important because it could lead to safer and more efficient lighting solutions. Who this helps: Patients and consumers looking for safer and more energy-efficient lighting options.

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This study looked at how combining resistance exercise with whole body vibration and blood flow restriction affects memory and brain function in older adults. Researchers found that accuracy in memory tasks improved after exercise, especially in participants using both whole body vibration and blood flow restriction, who showed the biggest benefits. These improvements are linked to increased levels of norepinephrine, a brain chemical that may help enhance memory. Who this helps: This research is beneficial for older adults looking to improve their cognitive health and memory performance.

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This study examined the expression of housekeeping genes, which are essential for basic cellular functions, in different types of human tissues and among individual people. Researchers analyzed gene expression data from over 16,000 samples and found that the stability of these genes varies based on the specific tissue type, leading to the identification of more reliable housekeeping genes. This is important because having consistent reference genes can improve the accuracy of biological research. Who this helps: This benefits researchers and scientists conducting studies in molecular biology.

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This study looked at how Tai Chi Chuan and aerobic exercise affect movement and thinking skills in people with early-stage Parkinson's disease. After 12 weeks of exercise, those who did aerobic workouts and Tai Chi both showed improvements in movement symptoms, with their scores on a specific rating scale decreasing significantly. Specifically, the aerobic group moved faster and showed better brain activity when doing memory tasks, highlighting the unique benefits of each exercise type for managing Parkinson's disease. Who this helps: Patients with early-stage Parkinson's disease.

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This study looked at how acne vulgaris affects eye health, specifically focusing on tear function and the condition of the eye's surface in 53 patients with acne compared to 54 healthy people. It found that patients with moderate-to-severe acne had lower tear stability and more issues with their tear glands, indicating a higher likelihood of experiencing dry eye symptoms. This matters because it highlights the connection between acne and eye discomfort, suggesting that people with acne may need additional eye care. Who this helps: Patients with moderate-to-severe acne vulgaris.

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This study looked at how badminton players of different skill levels perform on tasks that test their ability to focus and react to visual information. Researchers examined 54 players divided into elite, expert, and intermediate groups. They found that elite and expert players reacted faster and showed stronger brain activity than intermediate players, suggesting that higher skill levels improve focus and attention, but these benefits level off after a certain point in training. Who this helps: This helps coaches and players understand how skill level and training impact cognitive abilities in sports.

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This study looked at how a seaweed extract called Padina minor can help protect zebrafish from Candida albicans infection. Researchers divided the fish into groups and found that those fed with 1% extract showed the best growth and reduced inflammation related to the infection, while survival rates were similar across all groups. These findings are important because they highlight a potential new treatment option that may enhance disease resistance without negatively impacting fish health. Who this helps: This helps patients, particularly those with fungal infections, by exploring new treatment methods.

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Researchers created a portable device that quickly identifies Salmonella Typhimurium bacteria in food. It successfully detects tiny amounts of bacteria, as low as 2.83 nanograms per microliter, using a simple and energy-efficient method that can be operated remotely. This is important because it makes it easier and cheaper to test for foodborne pathogens, especially in areas with limited resources. Who this helps: This helps food safety inspectors and healthcare providers.

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This study examined a harmful infection caused by tiny organisms, called ciliates, on soft corals in the Northern Coral Triangle. The researchers found that these ciliates can grow three times larger after infecting the coral, leading to severe coral damage and stress, as indicated by increased levels of certain enzymes in the coral. They discovered that using an extract from the tropical plant Combretum indicum could help treat this infection without harming the corals, making it a valuable method for protecting coral reefs. Who this helps: This benefits coral reef conservationists, marine biologists, and aquaculturists working to maintain healthy coral ecosystems.

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This study focused on finding a fast and effective way to detect 61 types of hormones in water, including various glucocorticoids and androgens, using advanced testing technology. Researchers created a method that achieved an impressive detection limit of 0.05-1.50 ng/L and found that the hormones were present in water samples from the Taihu Basin region. This is important because monitoring these hormones can help ensure safe drinking water and address pollution issues. Who this helps: This benefits environmental scientists, water quality regulators, and communities relying on safe water sources.

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Researchers studied norovirus levels in wastewater to see how they relate to reported cases of illness in California. They found that monitoring wastewater helps public health authorities quickly identify and respond to outbreaks, giving them important data when they need it most. This is crucial because norovirus is a major cause of stomach illness, and better tracking can help prevent wider spread. Who this helps: This helps public health officials and the general public by providing timely information to control norovirus outbreaks.

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This study focused on a protein called CDCP1 and its role in cervical cancer. Researchers found that higher levels of CDCP1 in tumors were linked to worse outcomes for patients, as it negatively affects immune cells that fight cancer. Specifically, when they blocked CDCP1 in mice, it not only slowed tumor growth but also improved the immune response against the cancer. Who this helps: This research benefits patients with cervical cancer by suggesting a new treatment strategy.

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This study looked at how adding a specific type of MRI, called dynamic contrast-enhanced magnetic resonance angiography (DCE-MRA), can improve treatment for patients with chronic musculoskeletal pain using a method called transarterial microembolization (TAME). Researchers examined six patients with different pain conditions, and all experienced significant pain relief after TAME, with their average pain score dropping notably after treatment. Using DCE-MRA allowed doctors to better see and understand the blood vessels supplying the painful areas, which helped in planning the procedures and ultimately led to improved patient outcomes. Who this helps: This benefits patients with chronic musculoskeletal pain seeking effective treatment options.

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This study looked at how the cancer drug doxorubicin can work better when combined with another drug, bortezomib, to fight multiple myeloma (a type of blood cancer). Researchers found that when these two drugs were used together, doxorubicin increased the effectiveness of bortezomib by stopping the formation of structures that protect cancer cells from dying, allowing more cancer cells to be killed. Specifically, doxorubicin led to more misfolded proteins accumulating, which triggered cell death, showing promising results for treatment. Who this helps: This benefits patients with multiple myeloma by potentially improving their treatment options.

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This study looked at how accurately a digital mouth scanner measures teeth in children with different amounts of space between their teeth. They found that scanning was less accurate when the arch (the curve of the teeth) was longer, with the biggest differences in measurements for arches that were more than 81.9 mm in the upper jaw (maxilla) and 86.2 mm in the lower jaw (mandible). This matters because dental professionals need to be aware of these inaccuracies to provide better care for kids with spaced teeth. Who this helps: This helps pediatric dentists and orthodontists working with children.

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This research studied a new type of aluminum welding filler that includes more copper and magnesium, which could potentially improve the strength and durability of welds in high-strength aluminum alloys. The results showed that after heat treatment, the strength of the weld reached 310 MPa, almost matching the strength of the original metal, and remained strong at high temperatures and in saltwater. This matters because it could lead to better-performing and longer-lasting welds in various industries, especially where corrosion resistance is crucial. Who this helps: This benefits manufacturers and engineers who work with high-strength aluminum materials.