Dr. Nuvolone studies the health risks faced by communities living near geothermal power plants, which generate heat and electricity. Specifically, she investigates the effects of gases emitted by these plants, such as hydrogen sulfide, on residents' respiratory health. Her research looks at issues like asthma, lung cancer, and respiratory diseases, particularly how exposure levels to these gases can influence health outcomes.
Key findings
Exposure to low levels of hydrogen sulfide is linked to increased respiratory problems and hospitalizations, as well as higher rates of asthma and lung cancer.
High-level exposure to hydrogen sulfide correlates with paradoxically lower cancer rates but leads to increased hospitalizations for breathing and heart problems.
The review analyzed 19 studies and highlighted that many lacked individual tracking, indicating a need for better monitoring systems and stricter air quality controls.
Frequently asked questions
Does Dr. Nuvolone study the health effects of geothermal power plants?
Yes, she investigates how emissions from geothermal power plants affect the health of communities nearby.
What specific health issues has Dr. Nuvolone researched?
She has researched respiratory problems, asthma, lung cancer, and deaths related to respiratory diseases linked to exposure from geothermal emissions.
What has Dr. Nuvolone found about hydrogen sulfide exposure?
Her findings indicate that low-level exposure leads to significant respiratory health issues, while high-level exposure is linked to more hospitalizations despite lower cancer rates.
Are there recommendations from Dr. Nuvolone's work for residents near geothermal plants?
Yes, she emphasizes the need for better health monitoring and stricter air quality controls to protect public health.
Publications in plain English
Urinary levels of selected metals and associated individual-level characteristics in Tuscany, Italy: The EPIMETAL study.
2025
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
Caini S, Nuvolone D, de Bonfioli Cavalcabo N, Aprea MC, Ermini I +12 more
Plain English This study looked at the levels of certain metals in urine samples from 300 older adults in Tuscany, Italy, to understand how different factors affect these metal levels. Researchers found that the average levels of metals were lower than in previous surveys of contaminated areas, but factors like being female, smoking, and certain diets (like eating seafood and plant-based foods) were linked to higher metal levels. This information is important for public health, as it helps identify main sources of metal exposure and can guide efforts to reduce these risks in the community.
Who this helps: This helps patients and public health officials in Tuscany.
Levels and determinants of urinary and blood metals in the geothermal area of Mt. Amiata in Tuscany (Italy).
2023
Environmental science and pollution research international
Nuvolone D, Aprea MC, Stoppa G, Petri D, Barbone F +2 more
Plain English This study looked at how much heavy metals, like arsenic and mercury, are found in the urine and blood of people living in the volcanic area of Mt. Amiata, Italy. Researchers collected 2,034 samples and found that women and younger individuals generally had higher metal levels. Factors like smoking, diet (especially rice and fish), dental work, and drinking water sources also played a role in these levels.
Who this helps: This research benefits local residents and health officials by highlighting potential health risks from environmental exposure.
Long-term exposure to low-level arsenic in drinking water is associated with cause-specific mortality and hospitalization in the Mt. Amiata area (Tuscany, Italy).
2023
BMC public health
Nuvolone D, Stoppa G, Petri D, Voller F
Plain English This study looked at the health effects of long-term low-level arsenic exposure in drinking water for people living in the Mt. Amiata area of Tuscany, Italy, from 1998 to 2019. It found that people exposed to arsenic levels above 10 micrograms per liter had a higher risk of dying from non-accidental causes (7% increase) and a 14% higher risk of developing cancer in women. Additionally, long-term exposure was linked to greater hospitalization rates for issues such as cancer (10% increase for malignant tumors) and lung cancer (85% increase).
Who this helps: This research helps patients living in areas with arsenic-contaminated drinking water and informs public health officials and doctors about the risks associated with such exposure.
Exposure to low levels of hydrogen sulphide and its impact on chronic obstructive pulmonary disease and lung function in the geothermal area of Mt. Amiata in Italy: The cross-sectional InVETTA study.
2023
PloS one
Stoppa G, Nuvolone D, Petri D, Centi L, Nisticò F +3 more
Plain English This study looked at how low levels of hydrogen sulfide (H2S) from geothermal power plants in Mt. Amiata, Italy, affect the lung health of local residents. They examined the lung function of 2,018 adults and found that those exposed to higher levels of H2S had a 32.8% lower risk of having poor lung function (FEV1<80%) and a 51.7% lower risk for another measure (FVC<80%). This suggests that being around these low levels of H2S might actually be good for lung health.
Who this helps: This information benefits patients with lung conditions, especially those concerned about air quality and pollution.
Community Concern about the Health Effects of Pollutants: Risk Perception in an Italian Geothermal Area.
2022
International journal of environmental research and public health
Bustaffa E, Curzio O, Bianchi F, Minichilli F, Nuvolone D +4 more
Plain English This study looked at how people in the Mt. Amiata area of Italy feel about the health risks from pollutants produced by geothermal plants. Researchers surveyed 2,029 residents and found that 64% believed the environmental conditions were acceptable, while 32% thought they were serious but fixable, and 4% saw them as serious and unchangeable. Women, younger people, and those with higher education were more likely to feel at risk, especially if they noticed bad smells nearby. Understanding these perceptions can help further research on how pollution impacts health.
Who this helps: This helps residents of geothermal areas and public health officials.
Thallium Contamination of Drinking Water: Health Implications in a Residential Cohort Study in Tuscany (Italy).
2021
International journal of environmental research and public health
Nuvolone D, Petri D, Aprea MC, Bertelloni S, Voller F +1 more
Plain English This study looked at the health effects of thallium, a toxic metal, in the drinking water in Pietrasanta, Italy, between 2014 and 2015. Researchers found that while there was no increased risk of death or hospitalization among people living in areas with contaminated water, there was a 43% higher likelihood of low birth weight and a 40% higher risk of pre-term births for babies born to these residents. Understanding these impacts is important for protecting community health from environmental hazards.
Who this helps: This helps pregnant women and infants living in areas with thallium contamination.
Health effects associated with short-term exposure to hydrogen sulfide from geothermal power plants: a case-crossover study in the geothermal areas in Tuscany.
2020
International archives of occupational and environmental health
Nuvolone D, Petri D, Biggeri A, Barbone F, Voller F
Plain English This study looked at the health effects of short-term exposure to hydrogen sulfide gas from geothermal power plants in Tuscany, examining data from 2000 to 2017. Researchers found that men had a slight increase in risk of death from all causes and cardiovascular issues when hydrogen sulfide levels rose by 10 micrograms per cubic meter, with odds ratios of 1.11 for non-accidental deaths and 1.22 for cardiovascular deaths. Additionally, women were more likely to be hospitalized for respiratory problems with an odds ratio of 1.11.
Who this helps: This information is important for patients living near geothermal plants and healthcare providers.
Human biomonitoring to assess exposure to thallium following the contamination of drinking water.
2020
PloS one
Aprea MC, Nuvolone D, Petri D, Voller F, Bertelloni S +1 more
Plain English This study looked at how people in Pietrasanta, Italy, were exposed to harmful thallium levels in their drinking water between 2014 and 2016. Researchers collected urine and hair samples from over 2,000 residents and found significantly higher thallium levels in those living in contaminated areas compared to those from unaffected regions. Although thallium was found in the samples, it was mainly linked to where people lived and whether they consumed local water or produce; however, it was only related to sleep disturbances and not other health issues.
Who this helps: This benefits residents in contaminated areas and health officials monitoring water safety.
[Epidemiological study on the population resident in the neighbourhood of an incinerator in Tuscany Region (Central Italy)].
2020
Epidemiologia e prevenzione
Chellini E, Pieroni S, Martini A, Carreras G, Nuvolone D +2 more
Plain English This study looked at the health effects of emissions from two waste incinerators in a region of Tuscany, Italy. Researchers found that living near higher pollution levels was linked to increased rates of several cancers: liver cancer risk was 2.3 times higher from particulate matter and 4.4 times higher from dioxins, while non-Hodgkin lymphoma risk was 8.5 times higher from dioxins. These findings are important because they highlight potential health risks for local residents due to air pollution from the incinerators.
Who this helps: This helps patients and communities living near incinerators who may be at risk for these health issues.
The health of communities living in proximity of geothermal plants generating heat and electricity: A review.
2020
The Science of the total environment
Bustaffa E, Cori L, Manzella A, Nuvolone D, Minichilli F +2 more
Plain English Researchers reviewed 19 studies from New Zealand, Iceland, and Italy examining whether people living near geothermal power plants that produce heat and electricity suffer health problems from the gases these plants release, particularly hydrogen sulfide. They found that exposure to low levels of hydrogen sulfide increases respiratory problems, asthma, lung cancer, and respiratory disease deaths, while high-level exposure paradoxically shows lower cancer rates but more hospitalizations for breathing and heart problems.
The evidence suggests geothermal emissions do harm human health, but the research has major weaknesses—most studies looked at entire communities rather than tracking individuals—so better monitoring systems and stricter air quality controls around these plants are needed to protect public health.
Health effects associated with chronic exposure to low-level hydrogen sulfide from geothermoelectric power plants. A residential cohort study in the geothermal area of Mt. Amiata in Tuscany.
2019
The Science of the total environment
Nuvolone D, Petri D, Pepe P, Voller F
Plain English This study looked at the health effects of long-term low-level exposure to hydrogen sulfide gas from geothermal power plants in Mt. Amiata, Italy. Researchers analyzed health records of over 33,800 residents and found that higher exposure to hydrogen sulfide increased the risk of respiratory diseases, with a 12% higher risk of death and a 2% higher risk of hospitalization for these issues. However, exposure did not appear to increase the risk of cancer or cardiovascular diseases, which is important for understanding the potential health impacts of living near these power plants.
Who this helps: This information helps residents living near geothermal power plants and public health officials.
Environmental science and pollution research international
Nuvolone D, Petri D, Voller F
Plain English This study looked at how ozone, a harmful gas found in the air, affects human health. Researchers found that in 2013, ozone exposure caused about 16,000 premature deaths in the EU, equating to a loss of 192,000 years of life. Italy was particularly affected, with an estimated 3,380 premature deaths and a loss of 61 years of life for every 100,000 people due to ozone. This matters because it highlights the serious health risks associated with ozone pollution, emphasizing the need for better air quality management.
Who this helps: This helps patients, particularly those with respiratory issues, and policymakers focusing on air quality.
Health effects among a cohort exposed to low-level arsenic in a geothermal area of Tuscany, Italy.
2018
International archives of occupational and environmental health
Profili F, Nuvolone D, Barbone F, Aprea C, Centi L +3 more
Plain English This study looked at the health impacts of low-level arsenic exposure in a geothermal area of Tuscany, Italy, where drinking water contained arsenic levels below 50 micrograms per liter. Researchers followed about 900 people aged 20 to 55 from 1999 to 2015 and found that higher urinary arsenic levels were linked to increased risks of skin diseases and circulatory system issues, especially among men. For every 1 microgram per liter increase in urinary arsenic, the risk of skin diseases rose by 6%, and for circulatory diseases in men, it increased by 3%.
Who this helps: This research benefits patients living in areas with arsenic exposure, helping them understand health risks.
Mortality of populations residing in geothermal areas of Tuscany during the period 2003-2012.
2017
Annali dell'Istituto superiore di sanita
Bustaffa E, Minichilli F, Nuvolone D, Voller F, Cipriani F +1 more
Plain English This study looked at the death rates of people living in geothermal areas of Tuscany from 2003 to 2012. Researchers found that men in the southern part of Tuscany had a higher number of cancer deaths compared to other areas, while women in the northern part faced more death from brain and blood vessel diseases. Understanding these patterns is important for improving public health in these regions and investigating potential health risks linked to geothermal activity.
Who this helps: This helps patients living in geothermal areas and healthcare providers seeking to address local health challenges.
[Impacts of geocoding quality in environmental epidemiology studies: two case-studies in Tuscany Region (Central Italy)].
2016
Epidemiologia e prevenzione
Nuvolone D, Santini M, Pepe P, Cipriani F
Plain English This study looked at how accurate address geocoding is in two areas of Tuscany, Italy, to see how it affects health research. It found that the local geocoding system was more accurate than popular systems like Google and Bing, especially in the mountain area, where Google was off by more than 300 meters on average and sometimes by up to 7-8 kilometers. These inaccuracies can lead to serious mistakes in understanding how environmental factors impact health, highlighting the importance of using reliable geocoding services.
Who this helps: This benefits researchers and public health officials who need accurate data to assess health risks related to environmental exposure.
Ozone short-term exposure and acute coronary events: a multicities study in Tuscany (Italy).
2013
Environmental research
Nuvolone D, Balzi D, Pepe P, Chini M, Scala D +3 more
Plain English Researchers in Tuscany, Italy, studied how short-term exposure to ozone affects heart problems, specifically looking at heart attacks and sudden coronary deaths. They found that for every 10 micrograms per cubic meter increase in ozone, there was a 6.3% increase in deaths from coronary events outside of hospitals, particularly impacting women, older adults, and those with existing health issues. This matters because it highlights the health risks associated with ozone pollution and points to vulnerable groups who need more protection.
Who this helps: Patients with heart conditions and their doctors.
[Policies for the promotion of sustainable mobility and the reduction of traffic-related air pollution in the cities participating in the EpiAir2 project].
2013
Epidemiologia e prevenzione
Di Lonardo S, Nuvolone D, Forastiere F, Cadum E, Barchielli A +1 more
Plain English This research examined transportation policies in 15 Italian cities from 2006 to 2010, focusing on how well they promoted eco-friendly travel and cut down on air pollution. The study found that while many cities had updated their vehicle fleets, there were significant delays in improving public transport systems like subways and trams, leading to inconsistent progress across different cities. This matters because effective urban transport systems are essential for reducing pollution and improving the quality of life for residents.
Who this helps: Urban residents and city planners.
[State of health of populations residing in geothermal areas of Tuscany].
2012
Epidemiologia e prevenzione
Minichilli F, Nuvolone D, Bustaffa E, Cipriani F, Vigotti MA +1 more
Plain English This study looked at the health of people living in geothermal areas of Tuscany, investigating mortality and hospitalization rates, and certain birth outcomes like congenital malformations and low birth weight. The researchers found that from 2000 to 2006, men had a significant excess of deaths compared to expected numbers, particularly from infectious diseases and respiratory issues, with 2,312 deaths recorded versus 2,146 expected. In contrast, the women showed fewer excess deaths overall, but there was notable mortality from liver cirrhosis. Understanding these health patterns is important for addressing potential health risks associated with geothermal activity in these populations.
Who this helps: This information is valuable for healthcare providers and policymakers working to improve the health of residents in geothermal areas.
Geographical information system and environmental epidemiology: a cross-sectional spatial analysis of the effects of traffic-related air pollution on population respiratory health.
2011
Environmental health : a global access science source
Nuvolone D, Della Maggiore R, Maio S, Fresco R, Baldacci S +3 more
Plain English This study looked at how living near a busy road affects lung health. Researchers found that people living within 100 meters of the road experienced significantly worse respiratory issues, such as a 76% higher chance of wheezing and an 80% higher chance of being diagnosed with COPD, compared to those living further away. These findings are important because they show that traffic-related air pollution can harm breathing, especially for people living close to busy roads.
Who this helps: This helps patients living near major roadways and their doctors in understanding the health risks of air pollution.
Short-term association between ambient air pollution and risk of hospitalization for acute myocardial infarction: results of the cardiovascular risk and air pollution in Tuscany (RISCAT) study.
2011
American journal of epidemiology
Nuvolone D, Balzi D, Chini M, Scala D, Giovannini F +1 more
Plain English This study looked at how air pollution affects the risk of heart attacks (acute myocardial infarctions) in Tuscany, Italy, from 2002 to 2005. It found that increases in certain air pollutants, like fine particulate matter (PM10), nitrogen dioxide, and carbon monoxide, were linked to a higher risk of hospitalization for heart attacks, with a 1% increase per 10 micrograms of PM10. This is important because even low levels of pollution can harm vulnerable groups, such as the elderly and those with existing health conditions.
Who this helps: This helps patients, particularly the elderly and those with chronic health issues.
Body composition variables and leptin levels in functional hypothalamic amenorrhea and amenorrhea related to eating disorders.
2011
Journal of pediatric and adolescent gynecology
Bruni V, Dei M, Morelli C, Schettino MT, Balzi D +1 more
Plain English This study looked at two groups of young women who were not having periods: one group had issues related to eating disorders, while the other faced stressful life events. They found that women with eating disorders had a lower body mass index and lower levels of fat and muscle compared to those with stress-related issues, along with lower levels of leptin, a hormone linked to fat storage. These results show that understanding body composition and hormone levels can help better distinguish between the causes of amenorrhea, aiding in more accurate diagnoses and treatments.
Who this helps: This benefits doctors and healthcare providers when diagnosing and treating women with period problems related to eating disorders or stress.
Plain English This study looked at how polycystic ovary syndrome (PCOS) affects young girls, specifically focusing on 250 girls in their early teenage years. The researchers found that being overweight significantly worsens symptoms of PCOS and its impact on blood sugar levels. This is important because it highlights the need for early interventions and support for young girls who are overweight to help manage PCOS effectively.
Who this helps: Patients, particularly young girls with PCOS.
[Assessing the effectiveness of local transport policies for improvements in urban air quality and public health: a review of scientific literature].
2009
Epidemiologia e prevenzione
Nuvolone D, Barchielli A, Forastiere F,
Plain English This study looked at how local transportation policies impact air quality and public health by reviewing 19 different scientific articles. It found that better transport policies can lead to cleaner air and improved health, especially regarding respiratory and heart conditions, but the effects can be hard to measure due to various influencing factors. Understanding these impacts is crucial for creating effective local strategies that protect both the environment and people’s health.
Who this helps: This helps urban planners and local governments in making informed decisions.
[Traffic patterns regulations to reduce air pollution in the Italian cities participating in the EpiAir Project].
2009
Epidemiologia e prevenzione
Nuvolone D, Barchielli A, Forastiere F,
Plain English This study looked at how cities in Italy have changed their traffic rules to reduce air pollution between 2001 and 2007. Researchers found that while there were improvements in vehicle emissions, the number of cars per person was still higher than average in Europe, and cities saw an overall increase in vehicles, particularly diesel cars. Better transport policies, like promoting public transport and reducing car traffic, were noted, but these have not been effective enough to significantly improve air quality due to challenges like unclear regulations and a lack of proper enforcement.
Who this helps: This helps patients and residents in urban areas who are affected by poor air quality.